Revolution Medicines (RVMD)
NASDAQ:RVMD
Cetuximab, Daraxonrasib, Ivonescimab, Elironrasib, Zoldonrasib, Carboplatin/Cisplatin + Pemetrexed
Advanced Solid Tumors, Non-Small Cell Lung Cancer (Nsclc), Nsclc, Metastatic Solid Tumors, Colorectal Cancer (Crc), Crc
Phase I/II
Recruiting
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
Feb 02, 2026
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Cetuximab, Daraxonrasib, Rmc-5127
Pancreatic Cancer, Advanced Solid Tumors, Non-Small Cell Lung Cancer (Nsclc), Nsclc, Pancreatic Adenocarcinoma, Colorectal Cancer (Crc), Pdac, Crc, Pancreatic Ductal Adenocarcinoma (Pdac), Lung Cancer (Nsclc)
Phase I
Recruiting
Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors
Jan 09, 2026
Rmc-6236, Tng462, Rmc-9805
Pancreatic Cancer Metastatic, Lung Cancer, Nsclc, Pdac, Pdac - Pancreatic Ductal Adenocarcinoma, Ras Mutation, Mtap Deletion, Thoracic Cancer
Phase I/II
Recruiting
Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients
Mar 28, 2025
Gemcitabine, Nab-Paclitaxel, Oxaliplatin, Irinotecan, Rmc-6236, Leucovorin, 5-Fluorouracil, Liposomal Irinotecan
Pancreatic Cancer, Pdac, Pdac - Pancreatic Ductal Adenocarcinoma
Phase III
Recruiting
Phase 3 Study of Daraxonrasib (RMC-6236) in Patients With Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
Sep 20, 2024
Gemcitabine, Bevacizumab, Nab-Paclitaxel, Rmc-6236, Cetuximab, Rmc-9805, Mfolfox6 Regimen, Mfolfirinox Regimen
Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Metastatic Pancreatic Ductal Adenocarcinoma, Pdac, Crc, Gastrointestinal Cancer
Phase I/II
Recruiting
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
May 20, 2024
Pembrolizumab, Rmc-6291, Pemetrexed, Rmc-6236, Carboplatin, Cisplatin, Rmc-9805
Non-Small Cell Lung Cancer, Nsclc, Kras, Nras, Hras-Mutated Nsclc, Kras G12c-Mutated Solid Tumors, Lung Cancer, Lung Cancer Stage Iv, Advanced Solid Tumor, Cancer, Ras G12d-Mutated Nsclc
Phase I/II
Recruiting
Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC
Nov 30, 2023
FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Revolution Medicines (RVMD) have in its pipeline
RVMD is currently developing the following drugs: Cetuximab, Daraxonrasib, Ivonescimab, Elironrasib, Zoldonrasib, Carboplatin/Cisplatin + Pemetrexed, Cetuximab, Daraxonrasib, Rmc-5127, Daraxonrasib. These drug candidates are in various stages of clinical development as the company works toward FDA approval.