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Cartesian Therapeutics (RNAC)
NASDAQ:RNAC
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Cartesian Therapeutics (RNAC) AI Stock Analysis

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RNAC

Cartesian Therapeutics

(NASDAQ:RNAC)

Rating:48Neutral
Price Target:
$13.50
▲(0.30%Upside)
The overall stock score of 48 reflects significant financial challenges, as evidenced by declining revenues, operational losses, and negative equity. Technical analysis suggests some short-term positive momentum, but valuation remains a major concern with a negative P/E ratio. Investors should be cautious due to the company's reliance on external financing and lack of earnings call insights.
Positive Factors
Clinical Trial Progress
The initiation of the Phase 3 AURORA trial for Descartes-08 in myasthenia gravis comes on schedule, aligning with prior guidance.
Efficacy and Safety
Descartes-08 has demonstrated impressive depth of response in MG that is durable for 12-18+ months in all patients with a single 6W course and does not require conditioning.
Financial Health
Cartesian ended 1Q25 with $182.1M in cash and equivalents which the company is guiding as sufficient to fund operations through completion of the Phase 3 AURORA trial and into mid-2027.
Negative Factors
Clinical Data Concerns
There remains significant upside potential in RNAC shares as Descartes-08/15's enabling features vs. DNA CAR T therapies in I&I continue to become better understood by investors.
Clinical Trial Risks
Risks include delays in moving candidates through trials and failure to generate favorable clinical data, particularly with Descartes-08 in myasthenia gravis.

Cartesian Therapeutics (RNAC) vs. SPDR S&P 500 ETF (SPY)

Cartesian Therapeutics Business Overview & Revenue Model

Company DescriptionSelecta Biosciences, Inc., a clinical-stage biopharmaceutical company, engages in the research and development of nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. The company's lead therapeutic gene therapy program is SEL-302 that is in Phase I clinical trial to enhance the treatment of methylmalonic acidemia. It is also developing biologic therapies, such as SEL-212 that is in Phase III clinical trials for the treatment of chronic refractory gout; and product candidates to treat IgA-mediated diseases, including IgA nephropathy, linear IgA bullous dermatitis, IgA pemphigus, and Henoch-Schonlein purpura. In addition, the company is developing gene therapies comprising for the treatment of pompe disease, duchenne muscular dystrophy, limb-girdle muscular dystrophy, lysosomal storage disorder, and other autoimmune diseases. Further, it develops tolerogenic therapies to treat autoimmune diseases. The company has license and collaboration agreements with Ginkgo Bioworks Holdings, Inc.; Genovis AB (publ.); Cyrus Biotechnology, Inc.; IGAN Biosciences, Inc.; Astellas Therapeutics, Inc.; Takeda Pharmaceuticals USA, Inc.; Swedish Orphan Biovitrum AB (publ.); Sarepta Therapeutics, Inc.; Asklepios Biopharmaceutical, Inc.; Massachusetts Institute of Technology; and Shenyang Sunshine Pharmaceutical Co., Ltd. Selecta Biosciences, Inc. was incorporated in 2007 and is headquartered in Watertown, Massachusetts.
How the Company Makes MoneyCartesian Therapeutics makes money through the development and commercialization of its RNA-based cell therapies. Revenue streams include partnerships with pharmaceutical companies for co-development and licensing agreements, as well as potential future sales of approved therapeutic products. The company may also receive funding through research grants and collaborations with academic institutions. Additionally, strategic partnerships and investments provide financial support and contribute to its earnings.

Cartesian Therapeutics Financial Statement Overview

Summary
Cartesian Therapeutics is facing significant financial challenges, with declining revenues, high operational losses, negative equity, and cash outflows. These factors highlight financial instability and raise concerns about the company's long-term sustainability.
Income Statement
32
Negative
Cartesian Therapeutics shows a concerning trend in profitability, with a negative TTM net profit margin of -112.1% and a declining revenue trend. The gross profit margin remains high at 99.4% in the TTM, but the company struggles with negative EBIT and EBITDA margins, indicating operational inefficiencies and high costs relative to revenue.
Balance Sheet
25
Negative
The company's balance sheet is weak, highlighted by a negative stockholders' equity of -$21.79 million in the TTM, indicating financial distress. The debt-to-equity ratio cannot be calculated due to negative equity, and the equity ratio is also negative. These factors point to potential liquidity issues and high leverage risk, despite having substantial cash reserves.
Cash Flow
40
Negative
Cartesian Therapeutics has a negative free cash flow in the TTM of -$40.43 million, indicating cash outflow concerns. The operating cash flow to net income ratio shows operational cash drain, reflecting inefficiencies. However, significant financing cash flow suggests reliance on external funding to sustain operations.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue38.91M26.00M110.78M85.08M16.60M
Gross Profit38.91M24.45M108.74M85.08M16.60M
EBITDA-77.14M-235.06M39.84M-5.16M-65.59M
Net Income-77.42M-219.71M35.38M-25.69M-68.88M
Balance Sheet
Total Assets435.02M305.05M165.89M159.88M165.44M
Cash, Cash Equivalents and Short-Term Investments212.61M76.91M134.60M128.06M138.69M
Total Debt13.98M10.96M37.92M35.28M35.35M
Total Liabilities441.82M745.23M72.06M137.36M183.44M
Stockholders Equity-6.80M-440.18M93.83M22.52M-18.01M
Cash Flow
Free Cash Flow-32.77M-51.37M-32.83M-61.47M34.07M
Operating Cash Flow-23.67M-51.16M-31.63M-60.38M34.88M
Investing Cash Flow-8.74M34.61M-15.00M-17.14M-741.00K
Financing Cash Flow168.43M-13.14M39.22M52.90M14.43M

Cartesian Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price13.46
Price Trends
50DMA
10.88
Positive
100DMA
12.12
Positive
200DMA
15.91
Negative
Market Momentum
MACD
0.60
Negative
RSI
61.63
Neutral
STOCH
56.37
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RNAC, the sentiment is Positive. The current price of 13.46 is above the 20-day moving average (MA) of 12.20, above the 50-day MA of 10.88, and below the 200-day MA of 15.91, indicating a neutral trend. The MACD of 0.60 indicates Negative momentum. The RSI at 61.63 is Neutral, neither overbought nor oversold. The STOCH value of 56.37 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for RNAC.

Cartesian Therapeutics Risk Analysis

Cartesian Therapeutics disclosed 46 risk factors in its most recent earnings report. Cartesian Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cartesian Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (46)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
$419.01M-27.40%15.40%35.42%
52
Neutral
$987.71M-34.26%271.44%26.65%
48
Neutral
$347.53M-938.38%38.82%-645.78%
46
Neutral
C$201.68M-3.28-23.14%1.87%20.75%-0.36%
46
Neutral
$588.32M-79.51%-100.00%10.73%
43
Neutral
$434.03M-56.24%9.22%
41
Neutral
$544.39M-39.06%-48.01%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RNAC
Cartesian Therapeutics
13.46
-3.12
-18.82%
ORKA
Oruka Therapeutics
14.23
-5.58
-28.17%
ARCT
Arcturus Therapeutics
14.95
-8.03
-34.94%
ATYR
aTyr Pharma
5.56
3.33
149.33%
VERV
Verve Therapeutics
11.13
3.65
48.80%
AURA
Aura Biosciences Inc
7.06
-3.21
-31.26%

Cartesian Therapeutics Corporate Events

Executive/Board ChangesShareholder Meetings
Cartesian Therapeutics Holds Annual Stockholders Meeting
Neutral
Jun 16, 2025

On June 13, 2025, Cartesian Therapeutics, Inc. held its Annual Meeting of Stockholders, where 21,868,804 shares were represented, accounting for approximately 84.31% of the company’s outstanding stock. During the meeting, three Class III Directors were elected to serve until the 2028 Annual Meeting, the compensation of the company’s named executive officers was approved on a non-binding basis, and Ernst & Young LLP was ratified as the independent registered public accounting firm for the year ending December 31, 2025.

The most recent analyst rating on (RNAC) stock is a Buy with a $43.00 price target. To see the full list of analyst forecasts on Cartesian Therapeutics stock, see the RNAC Stock Forecast page.

Executive/Board Changes
Cartesian Therapeutics CTO Transition to Consultant Role
Neutral
Apr 29, 2025

On April 29, 2025, Cartesian Therapeutics, Inc. announced that its Chief Technology Officer, Metin Kurtoglu, will end his employment with the company on May 1, 2025. Following this, he will transition to a consulting role from May 1, 2025, to April 30, 2026. The agreements include a separation deal where Dr. Kurtoglu will release any claims against the company in exchange for severance benefits, including 12 months’ salary, a pro-rated bonus, and accelerated vesting of equity awards.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 24, 2025