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Rafael Holdings Inc (RFL)
NYSE:RFL
US Market

Rafael Holdings (RFL) AI Stock Analysis

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RFL

Rafael Holdings

(NYSE:RFL)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$1.00
▼(-18.03% Downside)
Rafael Holdings faces significant challenges with profitability and cash flow, despite a strong balance sheet. Technical indicators suggest a bearish trend, and valuation metrics are unattractive due to negative earnings. These factors collectively result in a low overall stock score.
Positive Factors
Revenue Growth
The company's consistent revenue growth indicates positive sales momentum, suggesting potential for future expansion and market penetration.
Balance Sheet Strength
Minimal leverage reduces financial risk, providing the company with greater flexibility to invest in growth opportunities and withstand economic downturns.
Real Estate Diversification
Diversification into real estate offers a stable revenue stream, reducing dependency on biopharmaceutical operations and enhancing overall business resilience.
Negative Factors
Profitability Challenges
Ongoing operational challenges and negative profitability metrics indicate inefficiencies that could hinder long-term financial health and shareholder returns.
Cash Flow Issues
Poor cash flow management may limit the company's ability to fund operations and growth initiatives, posing a risk to its financial stability.
Leadership Changes
Leadership changes can create uncertainty and may impact strategic direction, potentially affecting long-term governance and operational effectiveness.

Rafael Holdings (RFL) vs. SPDR S&P 500 ETF (SPY)

Rafael Holdings Business Overview & Revenue Model

Company DescriptionRafael Holdings, Inc. (RFL) is a biopharmaceutical company focused on advancing innovative therapies to treat cancer and other life-threatening diseases. The company operates primarily in the healthcare sector, with a core emphasis on developing and commercializing targeted drug therapies. Rafael Holdings also engages in real estate investments, which provide additional financial stability and diversification to its business model.
How the Company Makes MoneyRafael Holdings generates revenue through its biopharmaceutical operations, particularly by developing and potentially commercializing drug candidates that target various forms of cancer. The company may receive milestone payments and royalties from partnerships with larger pharmaceutical companies for the development and commercialization of its therapies. Additionally, Rafael Holdings has a portfolio of real estate assets that contribute to its revenue through leasing and property management activities. The combination of these revenue streams, alongside strategic collaborations and partnerships in the pharmaceutical industry, underpins the company's financial performance.

Rafael Holdings Financial Statement Overview

Summary
Rafael Holdings shows strong revenue growth and gross profit margins, but faces significant profitability and cash flow challenges. The balance sheet is robust with low leverage, yet the negative return on equity highlights inefficiencies.
Income Statement
45
Neutral
Rafael Holdings shows a strong gross profit margin of 88.44% for the latest year, indicating efficient cost management. However, the company is struggling with profitability, as evidenced by a negative net profit margin of -33.28% and negative EBIT and EBITDA margins. Revenue growth is positive at 25.27%, but the persistent losses highlight significant challenges in achieving sustainable profitability.
Balance Sheet
50
Neutral
The balance sheet reflects a strong equity position with a low debt-to-equity ratio of 0.007, suggesting minimal leverage risk. However, the return on equity is negative at -32.33%, indicating that the company is not generating returns on its equity investments. The equity ratio is healthy, but the negative ROE points to inefficiencies in asset utilization.
Cash Flow
40
Negative
Cash flow analysis reveals a concerning trend with negative operating cash flow and free cash flow. Despite a significant free cash flow growth rate of 65.14%, the operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly positive, suggesting some alignment between cash flow and accounting profits.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue917.00K637.00K279.00K410.00K3.97M
Gross Profit495.00K483.00K279.00K410.00K3.90M
EBITDA-32.25M-66.79M-8.67M-139.89M-23.34M
Net Income-30.52M-34.41M-1.88M-124.66M-25.15M
Balance Sheet
Total Assets114.11M96.83M98.83M118.32M154.06M
Cash, Cash Equivalents and Short-Term Investments52.77M65.94M79.51M63.23M7.85M
Total Debt692.00K2.39M0.0015.00M14.53M
Total Liabilities15.74M10.57M2.20M21.11M17.35M
Stockholders Equity94.39M82.19M100.29M100.52M122.29M
Cash Flow
Free Cash Flow-18.93M-7.98M40.79M-26.08M-15.81M
Operating Cash Flow-18.92M-7.80M-10.89M-26.08M-15.60M
Investing Cash Flow44.03M-10.82M21.21M-63.80M-7.26M
Financing Cash Flow24.83M-179.00K-15.22M103.86M29.39M

Rafael Holdings Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.22
Price Trends
50DMA
1.30
Negative
100DMA
1.39
Negative
200DMA
1.57
Negative
Market Momentum
MACD
>-0.01
Positive
RSI
43.52
Neutral
STOCH
5.13
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For RFL, the sentiment is Negative. The current price of 1.22 is below the 20-day moving average (MA) of 1.29, below the 50-day MA of 1.30, and below the 200-day MA of 1.57, indicating a bearish trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 43.52 is Neutral, neither overbought nor oversold. The STOCH value of 5.13 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for RFL.

Rafael Holdings Risk Analysis

Rafael Holdings disclosed 78 risk factors in its most recent earnings report. Rafael Holdings reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Rafael Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (65)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
$2.17B12.193.79%4.94%3.15%1.96%
50
Neutral
$35.31M-1.28-43.75%32.78%36.50%
48
Neutral
$98.06M-0.69-42.01%-3.22%-280.23%
45
Neutral
$63.68M-1.41-34.57%47.63%48.30%
44
Neutral
$50.87M-0.72-104.99%-36.25%11.92%
* Real Estate Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
RFL
Rafael Holdings
1.20
-0.66
-35.48%
MAYS
JW Mays
37.75
-6.25
-14.20%
NEN
New England Realty Associates Partnershi
64.15
-11.69
-15.41%
FTHM
Fathom Holdings
1.03
-0.51
-33.12%
OPAD
Offerpad Solutions
1.40
-2.02
-59.06%
STHO
Star Holdings
7.61
-1.81
-19.21%

Rafael Holdings Corporate Events

Delistings and Listing ChangesM&A Transactions
Rafael Holdings Issues Warrants Amid Cyclo Merger
Neutral
Dec 2, 2025

Rafael Holdings, Inc. has issued 1,078,796 warrants, exercisable for 380,253 shares of its Class B common stock, as part of a merger with Cyclo Therapeutics, Inc. These warrants, listed on the NYSE American under the symbol ‘RFL-WT,’ were exchanged for Cyclo’s existing warrants and are set to expire on December 11, 2025.

Executive/Board Changes
Rafael Holdings Appoints Alan Grayson to Board
Neutral
Oct 28, 2025

On October 23, 2025, Rafael Holdings announced the appointment of Alan Grayson to its Board of Directors, following the passing of Stephen Greenberg, the Lead Independent Director. Grayson, a former Member of Congress and experienced attorney, will serve on several committees, while Markus Sieger, an existing board member, was appointed as Chair of the Audit Committee and Lead Independent Director. These changes aim to fill the leadership void left by Greenberg’s passing and strengthen the company’s governance structure.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 18, 2025