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Quantum-Si (QSI)
NASDAQ:QSI
US Market

Quantum-Si (QSI) AI Stock Analysis

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QSI

Quantum-Si

(NASDAQ:QSI)

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Neutral 46 (OpenAI - 5.2)
Rating:46Neutral
Price Target:
$0.73
▼(-2.40% Downside)
Action:ReiteratedDate:03/04/26
The score is mainly held back by weak financial performance (very small, inconsistent revenue with large losses and ongoing cash burn) and bearish technicals (below key moving averages with negative MACD). The earnings call provides partial support through a strong cash runway and tighter spending plans plus Proteus development progress, but near-term revenue guidance is very low and execution/commercialization risk remains high. Valuation offers limited signal due to negative earnings and no dividend.
Positive Factors
Cash runway / balance sheet
A liquid balance sheet with $215.8M supporting operations into Q2 2028 materially lowers near‑term financing risk and gives management time to finish Proteus development, execute commercialization, and build consumable demand without forced dilution or rushed cost cuts.
Negative Factors
Very low and inconsistent revenue
Revenue remains tiny relative to the cost base and is moving inconsistently, undermining unit economics and margin stability. Sustained low top line limits reinvestment, makes scaling consumables dependent on future instrument adoption, and prolongs negative operating leverage.
Read all positive and negative factors
Positive Factors
Negative Factors
Cash runway / balance sheet
A liquid balance sheet with $215.8M supporting operations into Q2 2028 materially lowers near‑term financing risk and gives management time to finish Proteus development, execute commercialization, and build consumable demand without forced dilution or rushed cost cuts.
Read all positive factors

Quantum-Si (QSI) vs. SPDR S&P 500 ETF (SPY)

Quantum-Si Business Overview & Revenue Model

Company Description
Quantum-Si incorporated, a life sciences company, develops a single molecule detection platform for sample preparation and sequencing. It offers a proprietary single molecule detection platform for use in semiconductor industry to field proteomics...
How the Company Makes Money
Quantum-Si generates revenue primarily through (1) instrument sales of its protein sequencing platform(s), (2) recurring consumables and reagents used per run (a razor/razorblade-style model where the installed base drives repeat purchases), and (...

Quantum-Si Key Performance Indicators (KPIs)

Any
Any
Revenue by Segment
Revenue by Segment
Details revenue contributions from each business unit, highlighting which areas are most lucrative and where growth or decline is occurring.
Chart InsightsRevenue remains overwhelmingly driven by product sales and showed a sharp run-up into late‑2024 followed by a sustained pullback through 2025, exposing high concentration and sensitivity to capital‑sales headwinds. Management’s 12 academic placements, successful Proteus prototype runs, and new kit releases signal potential to rebuild instrument and consumable momentum and to grow recurring reagent revenue—but long biotech/pharma sales cycles, NIH funding uncertainty and a one‑time lease charge keep near‑term traction uncertain despite a healthy cash runway.
Data provided by:The Fly

Quantum-Si Earnings Call Summary

Earnings Call Date:Mar 03, 2026
(Q4-2025)
|
% Change Since: |
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Neutral
The call presents a mixed but deliberate narrative: strong technical progress on Proteus, meaningful product and scientific milestones, a successful placement program and a healthy cash position that supports execution. These positives are tempered by very low near-term revenue, Q4 margin compression, significant GAAP charges and the need to demonstrate commercial traction and reliable manufacturing for Proteus. Management frames 2026 as a planned transition year prioritizing long-term platform value over near-term revenue.
Positive Updates
Strong Balance Sheet and Runway
Cash, cash equivalents and marketable securities of $215.8M as of 12/31/2025, providing a runway into Q2 2028 and supporting planned Proteus development and operations.
Negative Updates
Very Low Near-Term Revenue
Revenue for Q4 2025 was $451,000 and full-year 2025 revenue was $2.4M; management guides 2026 total revenue of approximately $1.0M as 2026 is a deliberate transition year focused on Proteus market prep rather than instrument sales.
Read all updates
Q4-2025 Updates
Negative
Strong Balance Sheet and Runway
Cash, cash equivalents and marketable securities of $215.8M as of 12/31/2025, providing a runway into Q2 2028 and supporting planned Proteus development and operations.
Read all positive updates
Company Guidance
Management guided 2026 as a deliberate transition year, forecasting total revenue of approximately $1.0M (driven largely by consumables and services), adjusted operating expenses of $98M or less (adjusted OpEx excludes stock‑based compensation), and total cash usage of $93M or less; they closed 2025 with $215.8M in cash, cash equivalents and marketable securities (supporting operations into Q2 2028), expect a >25% increase in consumable kits run year‑over‑year, plan a modest inventory build for commercial readiness, and reiterated a Proteus launch by end‑2026 with a $425,000 list price; for context, Q4 2025 revenue was $0.451M (Q4 gross margin 27%), FY2025 revenue was $2.4M (FY gross margin 47%), Q4 GAAP OpEx was $21.2M (adjusted $18.3M) and FY GAAP OpEx was $117.3M (adjusted $86.3M), the company has placed 17 new customers via its placement program, expects very limited Platinum Pro capital sales in 2026 (including customer upgrade credits that can defer near‑term revenue), and plans adjusted spending to finish Proteus development while preserving financial flexibility.

Quantum-Si Financial Statement Overview

Summary
Low revenue scale and volatility alongside persistent large net losses and negative free cash flow weigh heavily. Offsetting positives are a low-debt balance sheet and historically solid gross margins on limited revenue, but the shrinking equity base and ongoing cash burn remain key risks.
Income Statement
22
Negative
Balance Sheet
58
Neutral
Cash Flow
26
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue2.44M3.06M1.08M0.000.00
Gross Profit-3.30M1.60M488.00K0.000.00
EBITDA-92.59M-103.98M-91.80M-111.77M-93.94M
Net Income-101.34M-101.01M-95.96M-132.44M-94.99M
Balance Sheet
Total Assets245.61M247.87M298.25M391.49M503.23M
Cash, Cash Equivalents and Short-Term Investments162.91M209.60M257.74M351.31M471.30M
Total Debt4.17M12.95M15.30M17.45M8.08M
Total Liabilities25.38M32.45M26.63M32.78M26.19M
Stockholders Equity220.23M215.42M271.62M358.71M477.03M
Cash Flow
Free Cash Flow-97.23M-92.38M-99.31M-101.30M-72.58M
Operating Cash Flow-94.72M-87.80M-94.04M-90.56M-66.81M
Investing Cash Flow-28.32M-32.67M143.43M137.19M-450.94M
Financing Cash Flow95.42M35.88M149.00K1.91M516.63M

Quantum-Si Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.75
Price Trends
50DMA
0.97
Negative
100DMA
1.14
Negative
200DMA
1.39
Negative
Market Momentum
MACD
-0.06
Positive
RSI
35.07
Neutral
STOCH
19.10
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For QSI, the sentiment is Negative. The current price of 0.75 is below the 20-day moving average (MA) of 0.87, below the 50-day MA of 0.97, and below the 200-day MA of 1.39, indicating a bearish trend. The MACD of -0.06 indicates Positive momentum. The RSI at 35.07 is Neutral, neither overbought nor oversold. The STOCH value of 19.10 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for QSI.

Quantum-Si Risk Analysis

Quantum-Si disclosed 69 risk factors in its most recent earnings report. Quantum-Si reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Quantum-Si Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$5.54B-8.47-32.00%45.66%
55
Neutral
$692.58M-7.71-32.72%-40.26%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$95.92M-1.64-26.04%13.77%-4.76%
46
Neutral
$161.80M-2.15-43.90%40.20%-4.07%
45
Neutral
$289.39M-4.58105.48%-3.91%37.89%
44
Neutral
$150.73M-1.20-85.20%46.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
QSI
Quantum-Si
0.75
-0.38
-33.89%
FHTX
Foghorn Therapeutics
4.93
1.49
43.31%
SEER
Seer
1.70
-0.01
-0.58%
DSGN
Design Therapeutics
11.23
7.83
230.29%
ERAS
Erasca
17.81
16.65
1435.34%
TNYA
Tenaya Therapeutics
0.69
0.20
39.36%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 04, 2026