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Quoin Pharmaceuticals
(NASDAQ:QNRX)
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Rating:43Neutral
Price Target:
$4.00
▼(-65.87% Downside)
Action:Reiterated
Date:06/26/26
The score is held down primarily by weak financial performance (no revenue, persistent losses, and heavy cash burn) and a bearish technical setup (price below key moving averages and negative MACD). Positive corporate milestones around QRX003 provide some upside support, but they do not offset the current lack of commercial traction and cash-flow durability; valuation signals are also constrained by negative earnings and no dividend.
Positive Factors
FDA acceptance of brand name
Conditional FDA acceptance of the QYLEKI brand and the stated plan to start a pivotal Phase 3 in 2H 2026 (targeting a 2027 NDA) materially reduces regulatory uncertainty and clarifies a realistic pathway to first-in-disease commercialization for Netherton Syndrome.
Negative Factors
No revenue & persistent losses
The company remains pre-commercial with no revenue and recurring operating and net losses; absent product approval or external funding, continued losses will deplete resources and constrain the firm’s ability to self-fund pivotal trials and early commercialization efforts over the next 2–6 months.
Read all positive and negative factors
Positive Factors
Negative Factors
FDA acceptance of brand name
Conditional FDA acceptance of the QYLEKI brand and the stated plan to start a pivotal Phase 3 in 2H 2026 (targeting a 2027 NDA) materially reduces regulatory uncertainty and clarifies a realistic pathway to first-in-disease commercialization for Netherton Syndrome.
Read all positive factors
Quoin Pharmaceuticals (QNRX) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$8.30M
Dividend YieldN/A
Average Volume (3M)629.04K
Price to Earnings (P/E)―
Beta (1Y)-0.88
Revenue GrowthN/A
EPS Growth86.17%
CountryUS
Employees4
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-17.68
Shares Outstanding2,008,418
10 Day Avg. Volume1,633,105
30 Day Avg. Volume629,040
Financial Highlights & Ratios
PEG Ratio0.02
Price to Book (P/B)1.65
Price to Sales (P/S)0.00
P/FCF Ratio-1.60
Enterprise Value/Market Cap0.74
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-246.78
Enterprise Value/Ebitda-0.36
Forecast
1Y Price Target
$23.25Price Target Upside98.38% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering4
EPS Forecast (FY)-6.48
Revenue Forecast (FY)N/A
Quoin Pharmaceuticals Business Overview & Revenue Model
Company Description
Quoin Pharmaceuticals, Ltd. operates as a specialized pharmaceutical firm, concentrating its efforts on devising therapeutic solutions for rare and orphan medical conditions. Its flagship offering, QRX003, is a topical lotion specifically formulat...
How the Company Makes Money
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Quoin Pharmaceuticals Earnings Call Summary
Earnings Call Date:Mar 13, 2024
(Q4-2023)
| % Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Positive
The earnings call reflects a generally positive outlook for Quoin Pharmaceuticals, with significant progress in clinical trials, strong commercial partnerships, and a solid financial position. However, challenges remain in managing cash burn and executing M&A strategies.Positive Updates
Transformational Year for Quoin
2023 was a transformational year for Quoin, marked by the release of the first-ever clinical data from a trial in Netherton syndrome subjects under an open IND with the FDA. The initial data was positive across several clinical endpoints with no safety signals.
Negative Updates
Net Loss and Cash Burn
Despite a decrease in net loss from $9.4 million in 2022 to $8.7 million in 2023, Quoin still faces financial challenges with ongoing R&D expenses and a net loss of $2 million in Q4 2023.
Read all updates
Q4-2023 Updates
Positive
Negative
Transformational Year for Quoin
2023 was a transformational year for Quoin, marked by the release of the first-ever clinical data from a trial in Netherton syndrome subjects under an open IND with the FDA. The initial data was positive across several clinical endpoints with no safety signals.
Read all positive updates
Company Guidance
During the Q4 2023 earnings call for Quoin Pharmaceuticals (QNRX), key guidance included updates on clinical trials for QRX003, a potential treatment for Netherton syndrome. The company implemented several FDA-cleared protocol amendments, including increasing study size, altering dosing frequency, and lowering eligibility age to 14 years. They have 9 commercial partnerships covering 61 countries and completed a $6.5 million public offering, with an $8 million equity line of credit to extend their cash runway into the second half of 2026. Despite a net loss of $8.7 million for 2023, Quoin remains the only company with an open IND for Netherton syndrome, positioning itself for a pivotal year in 2024.Quoin Pharmaceuticals Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
38
Negative
Cash Flow
9
Very Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Gross Profit | -24.93K | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| EBITDA | -16.88M | -15.70M | -8.86M | -8.58M | -8.56M | -20.27M |
| Net Income | -16.98M | -15.80M | -8.96M | -8.69M | -9.38M | -21.46M |
Balance Sheet | ||||||
| Total Assets | 15.69M | 20.39M | 15.71M | 12.17M | 14.46M | 9.36M |
| Cash, Cash Equivalents and Short-Term Investments | 3.12M | 3.82B | 14.06M | 10.69M | 12.85M | 7.48M |
| Total Debt | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |
| Total Liabilities | 6.92M | 7.27M | 6.50M | 6.51M | 7.05M | 8.70M |
| Stockholders Equity | 8.77M | 13.12M | 9.20M | 5.66M | 7.41M | 657.03K |
Cash Flow | ||||||
| Free Cash Flow | -15.86M | -13.54M | -7.86M | -7.86M | -8.73M | -6.35M |
| Operating Cash Flow | -15.86M | -13.54M | -7.86M | -7.86M | -8.48M | -5.72M |
| Investing Cash Flow | -3.01M | -4.28M | -1.89M | 2.19M | -10.15M | -625.00K |
| Financing Cash Flow | 18.19M | 18.01M | 10.97M | 5.22M | 14.01M | 13.50M |
Quoin Pharmaceuticals Technical Analysis
Negative
11.72
Price Trends
4.95
Negative
6.13
Negative
9.14
Negative
Market Momentum
-0.11
Negative
45.24
Neutral
27.23
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For QNRX, the sentiment is Negative. The current price of 11.72 is above the 20-day moving average (MA) of 4.45, above the 50-day MA of 4.95, and above the 200-day MA of 9.14, indicating a bearish trend. The MACD of -0.11 indicates Negative momentum. The RSI at 45.24 is Neutral, neither overbought nor oversold. The STOCH value of 27.23 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for QNRX.
Quoin Pharmaceuticals Risk Analysis
Quoin Pharmaceuticals disclosed 57 risk factors in its most recent earnings report. Quoin Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
Quoin Pharmaceuticals Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
53 Neutral | $6.19M | -0.27 | -162.83% | ― | ― | 75.60% | |
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
43 Neutral | $8.30M | -0.25 | -334.42% | ― | ― | 86.17% | |
43 Neutral | $2.56M | -0.02 | ― | ― | ― | 76.55% | |
42 Neutral | $4.12M | -0.26 | -46.34% | ― | ― | 71.38% | |
42 Neutral | $10.93M | ― | 764.53% | ― | 155.96% | 87.56% |
* Healthcare Sector Average
QNRX
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4.21
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Quoin Pharmaceuticals Corporate Events
Business Operations and StrategyProduct-Related Announcements
Quoin Advances QYLEKI Toward First Netherton Therapy
Positive
Jun 23, 2026
On June 23, 2026, Quoin Pharmaceuticals said the U.S. Food and Drug Administration had conditionally accepted QYLEKI as the proposed brand name for QRX003, its investigational topical lotion for Netherton Syndrome. QRX003, now in Phase 2 whole-bod...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Quoin Wins Japan Orphan Drug Status for QRX003
Positive
Jun 4, 2026
On March 11, 2026, Quoin Pharmaceuticals announced that Japan’s Ministry of Health, Labour and Welfare granted Orphan Drug Designation to QRX003 lotion (4%) for Netherton Syndrome, a severe genetic skin disorder with no approved treatments. ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.