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Pelthos Therapeutics (PTHS)
:PTHS
US Market

Pelthos Therapeutics (PTHS) AI Stock Analysis

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PTHS

Pelthos Therapeutics

(PTHS)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$26.00
▲(0.23% Upside)
The score is held back primarily by weak financial performance (large losses and ongoing cash burn) and a soft technical setup (below key short-to-mid moving averages). Offsetting factors include a constructive earnings update tied to the ZELSUVMI launch and supportive corporate actions that improve funding and expand the commercial portfolio, though valuation support is limited by negative earnings.
Positive Factors
Commercial Launch & Revenue Traction
A strong initial commercial launch provides a durable revenue base and real-world demand signals. Early traction validates market fit for the at‑home molluscum therapy, supports scale-up of distribution and prescribing habits, and materially de‑risks commercialization versus purely pipeline-stage peers.
Favorable Product Economics (Gross Margin)
A mid‑50s gross margin on current sales implies attractive unit economics. As fixed commercial costs are leveraged with volume, these margins can drive margin expansion and improved operating leverage, helping convert revenue growth into sustainable cash flow if GTN and SG&A are controlled.
Strengthened Liquidity via Non‑Dilutive Financing
A largely non‑dilutive, term loan facility with delayed amortization materially extends runway to execute launches and product relaunches. This financing reduces immediate equity dilution risk, provides capital for commercial scale and M&A integration, and improves near‑term balance sheet flexibility.
Negative Factors
Sustained Cash Burn & Large Losses
Persistent negative operating cash flow and deep operating losses indicate the business is not yet self‑funding. Continued cash burn raises reliance on external financing, increasing execution and refinancing risk that could impair long‑term viability if commercial ramp underperforms expectations.
Rising Gross‑to‑Net (GTN) Pressure
An increasing GTN percentage materially reduces realized net revenue from gross sales, pressuring margins and cash generation. If GTN settles higher, revenue forecasts and break‑even timelines become harder to achieve, making scale economics and return on promotional spend less favorable.
Execution & Scale Risk from Limited Internal Infrastructure
A very small internal headcount facing rapid commercial expansion and multiple product relaunches raises execution risk. Rapidly scaling sales, supply and integration of acquisitions can inflate SG&A and operational complexity, risking execution errors, higher costs, or slower-than-expected market penetration.

Pelthos Therapeutics (PTHS) vs. SPDR S&P 500 ETF (SPY)

Pelthos Therapeutics Business Overview & Revenue Model

Company DescriptionPelthos Therapeutics Inc., a bio-pharmaceutical company, develops and commercializes therapeutic products to help patients with unmet treatment burdens. The company offers ZELSUVMI for the treatment of molluscum contagiosum in adults and children 1 year of age and older. It also provides NITRICIL, a proprietary nitric oxide-based technology platform. The company was formerly known as Channel Therapeutics Corporation and changed its name to Pelthos Therapeutics Inc. in July 2025. Pelthos Therapeutics Inc. was founded in 2002 and is based in Durham, North Carolina.
How the Company Makes Money

Pelthos Therapeutics Financial Statement Overview

Summary
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
28
Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue7.41M0.000.000.000.00199.93K
Gross Profit4.02M0.000.000.00-209.05K61.35K
EBITDA-21.10M-7.17M-6.86M-2.32M0.000.00
Net Income-23.58M-7.96M-7.38M-2.46M-595.39K-660.58K
Balance Sheet
Total Assets126.43M1.37M96.39K55.07K0.0071.87K
Cash, Cash Equivalents and Short-Term Investments14.25M513.44K96.39K55.07K0.000.00
Total Debt3.48M2.19M1.27M540.43K1.10M241.79K
Total Liabilities68.18M4.08M6.54M3.76M3.68M3.65M
Stockholders Equity58.25M-2.71M-6.44M-3.71M-3.68M-3.58M
Cash Flow
Free Cash Flow-17.01M-5.79M-981.03K-1.57M-1.59M-3.63M
Operating Cash Flow-17.01M-5.79M-981.03K-1.57M-1.59M-3.63M
Investing Cash Flow2.76M0.000.000.000.000.00
Financing Cash Flow27.25M6.21M1.02M1.62M1.59M3.63M

Pelthos Therapeutics Risk Analysis

Pelthos Therapeutics disclosed 69 risk factors in its most recent earnings report. Pelthos Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Pelthos Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$101.80M-13.0010.35%-0.32%94.05%
56
Neutral
$127.12M-2.21234.73%81.16%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$77.48M-1.41
44
Neutral
$78.19M-0.74-398.50%30.16%
44
Neutral
$48.76M-0.62-50.60%1.40%
41
Neutral
$63.16M-1.84-234.46%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
PTHS
Pelthos Therapeutics
25.94
6.94
36.53%
IMUX
Immunic
0.64
-0.31
-33.05%
FBIO
Fortress Biotech
3.48
1.61
86.10%
VRCA
Verrica Pharmaceuticals
7.61
0.84
12.36%
TIL
Instil Bio
7.11
-13.86
-66.09%
TVGN
Tevogen Bio Holdings
0.33
-0.95
-74.53%

Pelthos Therapeutics Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Pelthos Therapeutics Secures $50 Million Venture Loan Financing
Positive
Jan 13, 2026

On January 12, 2026, Pelthos Therapeutics and its subsidiaries entered into a senior secured venture loan and security agreement with Horizon Technology Finance for a term loan facility of up to $50 million, of which $30 million was funded at closing and an additional $20 million may be drawn upon achieving specified milestones. The facility, maturing in January 2031, carries interest at prime plus 3.75% with interest-only payments through at least early 2029, is secured by substantially all of the borrowers’ assets, and includes customary covenants and default provisions, while Pelthos also issued Horizon five-year warrants to purchase 65,488 common shares at $27.49 per share. According to the company’s January 13, 2026 announcement, the largely non‑dilutive financing is intended to accelerate commercialization of ZELSUVMI, support the launches of Xepi and Xeglyze, and bolster working capital, strengthening Pelthos’ balance sheet and providing growth capital for its expanding dermatology portfolio with limited equity dilution to existing shareholders.

The most recent analyst rating on (PTHS) stock is a Hold with a $25.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Pelthos Therapeutics Details Q1 2026 Growth Strategy
Positive
Jan 12, 2026

On January 6, 2026, Pelthos Therapeutics’ board, acting on its compensation committee’s annual review, approved revisions to cash and equity compensation for non-employee directors effective January 1, 2026, increasing the annual cash retainer for the Non-Executive Chairman from $50,000 to $60,000 and introducing new cash retainers for members and chairs of the audit, compensation, and nominating and corporate governance committees, while maintaining the base director and committee member retainers. Under the updated policy, non-employee directors may receive an initial equity grant at the board’s discretion when they join, but will not receive recurring annual equity awards, a structure that brings Pelthos’s board pay more in line with its peer group and may support governance stability as the company scales its dermatology portfolio. On January 12, 2026, the company also posted a Q1 2026 corporate presentation outlining its strategy to build a differentiated cutaneous infection franchise around Zelsuvmi and the Xepi and Xeglyze acquisitions, highlighting the large addressable markets, expected product launch timelines through 2027, and a peak net revenue forecast of $175 million per year from Zelsuvmi alone by 2028, signaling an aggressive commercial growth plan aimed at strengthening its position in the dermatology therapeutics market.

The most recent analyst rating on (PTHS) stock is a Buy with a $75.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Business Operations and StrategyM&A Transactions
Pelthos Therapeutics Acquires Global Rights to Xeglyze
Positive
Jan 2, 2026

On December 23, 2025, Pelthos Therapeutics acquired from Australian biotech Hatchtech all rights and related assets to Xeglyze (abametapir), an FDA-approved topical prescription treatment for head lice, for a total purchase price of $1.8 million, following an earlier $450,000 down payment in November 2025 and completion of the transaction by the scheduled closing date of December 29, 2025. The deal gives Pelthos worldwide commercialization rights to the patent-protected pediculicide without future milestone or royalty obligations, adding a complementary, single-application head-lice therapy with both ovicidal and lousicidal activity to its portfolio and strengthening its commercial infrastructure in dermatology-related conditions, with plans to relaunch the product in 2027 and potentially expand its presence in a sizable pediatric head-lice market.

The most recent analyst rating on (PTHS) stock is a Buy with a $75.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Pelthos Therapeutics Adds Veteran Finance Executive to Board
Positive
Dec 23, 2025

On December 23, 2025, Pelthos Therapeutics expanded its Board of Directors from seven to eight members and appointed veteran finance executive Andrew J. Einhorn as an independent director, with a term running until the company’s 2026 annual meeting of shareholders. Einhorn, who has more than four decades of experience in investment banking, capital markets and C‑suite finance roles at clinical and commercial-stage life science companies, will serve on Pelthos’ Audit and Compensation Committees and receive standard non-employee director compensation, including a grant of 12,000 restricted stock units vesting on January 1, 2027, and an indemnification agreement consistent with those of other directors and officers. The move brings additional capital markets and strategic financial expertise to Pelthos’ boardroom as the company continues to build out its governance and financial leadership infrastructure following its emergence as a newly public, commercially focused biopharmaceutical company.

The most recent analyst rating on (PTHS) stock is a Buy with a $75.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Executive/Board ChangesShareholder Meetings
Pelthos Therapeutics Concludes 2025 Annual Stockholder Meeting
Positive
Dec 17, 2025

On December 17, 2025, Pelthos Therapeutics Inc. conducted its 2025 Annual Meeting of Stockholders where three key proposals were addressed. The election of seven directors to the board was approved, ensuring leadership continuity until the 2026 Annual Meeting. Additionally, stockholders approved a proposal to waive share issuance limits tied to senior secured convertible notes and ratified the appointment of CBIZ CPAs P.C. as the company’s independent auditor for the fiscal year ending December 31, 2025. These decisions reflect robust stakeholder participation and support for the company’s strategic and operational positioning.

The most recent analyst rating on (PTHS) stock is a Buy with a $75.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Financial DisclosuresM&A TransactionsPrivate Placements and FinancingProduct-Related Announcements
Pelthos Therapeutics Reports Q3 2025 Financial Results
Positive
Nov 13, 2025

Pelthos Therapeutics announced its financial results for the third quarter of fiscal 2025, highlighting the successful commercial launch of ZELSUVMI, an FDA-approved at-home treatment for molluscum contagiosum, which generated $7.1 million in net revenues since its launch in July 2025. The company also completed the acquisition of XEPI, a topical treatment for impetigo, and secured $18 million in financing to support its operations. These developments position Pelthos to capitalize on large market opportunities and unmet needs in pediatric dermatology.

The most recent analyst rating on (PTHS) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

M&A TransactionsPrivate Placements and FinancingProduct-Related Announcements
Pelthos Therapeutics Acquires Xepi and Secures Financing
Positive
Nov 7, 2025

On November 6, 2025, Pelthos Therapeutics acquired the U.S. commercialization rights to Xepi, a topical treatment for impetigo, from Biofrontera and Ferrer. This acquisition adds a complementary product to Pelthos’ portfolio, aimed at addressing antimicrobial resistance in pediatric dermatology. Concurrently, Pelthos closed an $18 million private convertible notes financing with investors, including Ligand Pharmaceuticals, to support the acquisition, relaunch Xepi, and accelerate the commercialization of ZELSUVMI. The financing reflects investor confidence and is expected to strengthen Pelthos’ balance sheet and support its commercial growth.

The most recent analyst rating on (PTHS) stock is a Buy with a $50.00 price target. To see the full list of analyst forecasts on Pelthos Therapeutics stock, see the PTHS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 14, 2026