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NextCure Inc (NXTC)
NASDAQ:NXTC

NextCure (NXTC) AI Stock Analysis

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NXTC

NextCure

(NASDAQ:NXTC)

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Neutral 54 (OpenAI - 5.2)
Rating:54Neutral
Price Target:
$11.00
▼(-19.88% Downside)
Action:ReiteratedDate:03/06/26
Overall score is held back primarily by weak financial performance (no revenue, ongoing losses and cash burn, and reduced equity), partially offset by a moderately positive technical trend and supportive pipeline/runway updates. Valuation provides limited support due to negative earnings and no dividend.
Positive Factors
Advancing ADC clinical programs
Advancing two ADC programs through Phase 1 dose-escalation (SIM0505 and LNCB74) creates durable R&D value drivers: upcoming SIM0505 data and broader enrollment for LNCB74 can materially de-risk assets, enable partnering/licensing opportunities, and support long-term pipeline value if signals are positive.
Negative Factors
Pre-revenue, persistent losses
The company remains pre-revenue with substantial recurring net losses, meaning sustainable operations depend on external capital. Persistent negative profitability limits reinvestment capacity and increases long-term execution risk if clinical programs do not produce value-driving outcomes.
Read all positive and negative factors
Positive Factors
Negative Factors
Advancing ADC clinical programs
Advancing two ADC programs through Phase 1 dose-escalation (SIM0505 and LNCB74) creates durable R&D value drivers: upcoming SIM0505 data and broader enrollment for LNCB74 can materially de-risk assets, enable partnering/licensing opportunities, and support long-term pipeline value if signals are positive.
Read all positive factors

NextCure (NXTC) vs. SPDR S&P 500 ETF (SPY)

NextCure Business Overview & Revenue Model

Company Description
NextCure, Inc., a clinical-stage biopharmaceutical company, engages in discovering and developing novel immunomedicines to treat cancer and other immune-related diseases by restoring normal immune function. Its lead product candidate is NC318, whi...
How the Company Makes Money
NextCure’s primary source of cash flows is funding from financing activities (e.g., issuing equity or other capital-raising transactions) because it is a clinical-stage company and does not have product sales from approved therapies. Operating rev...

NextCure Financial Statement Overview

Summary
Financial profile remains weak: $0 revenue from 2021–2025 with continued sizable losses (2025 net loss ~$55.8M) and persistent negative operating/free cash flow (~-$49.6M in 2025). Positives include narrowing losses versus 2022–2023 and low leverage (~$4.1M debt; debt-to-equity ~0.12), but sharply reduced equity (~$233.4M in 2021 to ~$34.9M in 2025) signals ongoing funding/dilution risk.
Income Statement
18
Very Negative
Balance Sheet
55
Neutral
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-2.19M-2.87M0.000.000.00
EBITDA-55.43M-54.34M-63.95M-71.78M-66.59M
Net Income-55.84M-55.65M-62.72M-74.73M-69.39M
Balance Sheet
Total Assets50.18M80.86M128.04M184.16M242.39M
Cash, Cash Equivalents and Short-Term Investments41.82M68.62M108.30M159.91M219.59M
Total Debt4.15M5.95M6.61M7.12M0.00
Total Liabilities15.24M15.39M13.62M16.63M9.00M
Stockholders Equity34.94M65.47M114.42M167.53M233.39M
Cash Flow
Free Cash Flow-49.61M-41.28M-53.79M-56.00M-59.60M
Operating Cash Flow-49.61M-40.80M-52.97M-53.89M-57.24M
Investing Cash Flow25.56M55.31M39.27M67.98M36.60M
Financing Cash Flow22.31M144.00K154.00K200.00K-3.27M

NextCure Technical Analysis

Technical Analysis Sentiment
Positive
Last Price13.73
Price Trends
50DMA
11.83
Negative
100DMA
12.04
Negative
200DMA
9.21
Positive
Market Momentum
MACD
-0.24
Negative
RSI
54.30
Neutral
STOCH
76.03
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For NXTC, the sentiment is Positive. The current price of 13.73 is above the 20-day moving average (MA) of 10.87, above the 50-day MA of 11.83, and above the 200-day MA of 9.21, indicating a neutral trend. The MACD of -0.24 indicates Negative momentum. The RSI at 54.30 is Neutral, neither overbought nor oversold. The STOCH value of 76.03 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for NXTC.

NextCure Risk Analysis

NextCure disclosed 70 risk factors in its most recent earnings report. NextCure reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

NextCure Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$41.44M-0.72-152.90%3.78%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
$7.41M-5.72-9.02%-1979.68%
45
Neutral
$7.18M-2.52-229.48%71.57%
44
Neutral
$238.44M-0.04506.72%-323.61%
41
Neutral
$7.25M-0.33-925.11%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
NXTC
NextCure
11.64
7.90
211.23%
NERV
Minerva Neurosciences
5.51
3.94
251.63%
MTVA
MetaVia
1.41
-18.83
-93.03%
ATON
AlphaTON Capital
0.31
-8.57
-96.52%
APM
Aptorum Group
0.91
0.09
10.98%

NextCure Corporate Events

Business Operations and StrategyFinancial DisclosuresProduct-Related Announcements
NextCure Updates ADC Pipeline Progress and Cash Runway
Positive
Jan 23, 2026
On January 23, 2026, NextCure reported program and financial updates, highlighting progress in its two antibody-drug conjugate candidates and outlining its cash position. The company plans to present Phase 1 dose-escalation data for SIM0505, a cad...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 06, 2026