Clinical Trial SuccessNuvalent reported positive topline data from the ongoing ALKOVE-1 study which paves the way for neladalkib to be filed as a 2L therapy for ALK-positive NSCLC patients.
Commercial PotentialThe company is well-positioned to become a commercial entity by the end of 2026, with expectations for zildesamtinib to receive accelerated approval as a therapy for ROS1-positive NSCLC.
Efficacy And SafetyNeladalkib showed good intracranial activity in the 2L patient cohort with an IC-ORR of 63% and an IC-CR of 21%.