NeOnc Technologies Holdings, Inc. (NTHI)
NASDAQ:NTHI
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NeOnc Technologies Holdings, Inc.
(NASDAQ:NTHI)
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Rating:42Neutral
Price Target:
$5.00
▼(-43.69% Downside)
Action:Reiterated
Date:05/19/26
The score is driven primarily by very weak financial performance (zero TTM revenue, deep losses, heavy cash burn, and negative equity), which raises financing and dilution risk. Technicals are also unfavorable with price below key longer-term moving averages and negative MACD, while valuation is constrained by ongoing losses (negative P/E) and no dividend support.
Positive Factors
Clinical de-risking (NEO212 RP2D)
Completion of NEO212 Phase 1 with a recommended Phase 2 dose and early efficacy signals materially reduces program risk. This validates the oral bioconjugation platform, enables a defined Phase 2 pathway, and strengthens the company’s negotiating leverage with regulators and partners over the medium term.
Negative Factors
Zero TTM revenue
No product revenue means the business is fully pre-commercial and dependent on financing to sustain operations. Without commercialization, revenue generation remains uncertain; the company must convert clinical progress to reimbursable therapies to achieve self-sustaining cash flow beyond the next funding cycles.
Read all positive and negative factors
Positive Factors
Negative Factors
Clinical de-risking (NEO212 RP2D)
Completion of NEO212 Phase 1 with a recommended Phase 2 dose and early efficacy signals materially reduces program risk. This validates the oral bioconjugation platform, enables a defined Phase 2 pathway, and strengthens the company’s negotiating leverage with regulators and partners over the medium term.
Read all positive factors
NeOnc Technologies Holdings, Inc. (NTHI) vs. SPDR S&P 500 ETF (SPY)
Market Cap
$138.91M
Dividend YieldN/A
Average Volume (3M)103.40K
Price to Earnings (P/E)―
Beta (1Y)1.54
Revenue GrowthN/A
EPS GrowthN/A
CountryUS
Employees8
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-1.94
Shares Outstanding26,013,136
10 Day Avg. Volume39,098
30 Day Avg. Volume103,402
Financial Highlights & Ratios
PEG Ratio0.00
Price to Book (P/B)-9.07
Price to Sales (P/S)3973.02
P/FCF Ratio-7.62
Enterprise Value/Market Cap0.79
Enterprise Value/RevenueN/A
Enterprise Value/Gross Profit-3.43K
Enterprise Value/Ebitda-3.17
Forecast
1Y Price Target
$16.00Price Target Upside80.18% Upside
Rating ConsensusStrong Buy
Number of Analyst Covering3
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
NeOnc Technologies Holdings, Inc. Business Overview & Revenue Model
Company Description
Neonc Technologies Holdings, Inc. develops novel molecular technology that provides enhanced targeted delivery of technologies for treating central nervous system diseases. Its lead products in development include NEO100, which is in Phase 2a clin...
NeOnc Technologies Holdings, Inc. Financial Statement Overview
Summary
Income Statement
6
Very Negative
Balance Sheet
12
Very Negative
Cash Flow
10
Very Negative
| Breakdown | Mar 2026 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|
Income Statement | |||||
| Total Revenue | 39.99K | 83.00K | 70.46K | 20.00K | 0.00 |
| Gross Profit | 39.99K | 83.00K | 70.46K | 20.00K | 0.00 |
| EBITDA | -59.61M | -9.10M | -12.20M | -2.85M | -3.26M |
| Net Income | -62.15M | -11.90M | -14.92M | -3.05M | -3.38M |
Balance Sheet | |||||
| Total Assets | 2.82M | 3.42M | 1.27M | 728.68K | 32.49K |
| Cash, Cash Equivalents and Short-Term Investments | 58.73K | 64.89K | 31.86K | 633.30K | 25.03K |
| Total Debt | 6.31M | 24.72K | 6.61M | 50.00K | 1.15M |
| Total Liabilities | 20.33M | 8.92M | 15.25M | 2.30M | 2.65M |
| Stockholders Equity | -17.51M | -5.50M | -13.99M | -1.58M | -2.62M |
Cash Flow | |||||
| Free Cash Flow | -20.86M | -4.21M | -1.88M | -881.74K | -396.69K |
| Operating Cash Flow | -20.36M | -4.21M | -1.88M | -881.74K | -396.69K |
| Investing Cash Flow | -500.00K | 0.00 | 0.00 | 0.00 | 0.00 |
| Financing Cash Flow | 20.86M | 4.25M | 1.28M | 1.49M | 250.00K |
NeOnc Technologies Holdings, Inc. Risk Analysis
NeOnc Technologies Holdings, Inc. disclosed 83 risk factors in its most recent earnings report. NeOnc Technologies Holdings, Inc. reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks
NeOnc Technologies Holdings, Inc. Peers Comparison
UnderperformOutperform
Sector (51)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
51 Neutral | $7.86B | -0.30 | -43.30% | 2.27% | 22.53% | -2.21% | |
50 Neutral | $13.14M | -0.92 | -356.99% | ― | ― | -152.00% | |
48 Neutral | $7.68M | -0.13 | -489.66% | ― | -84.76% | 79.01% | |
43 Neutral | $26.70M | -0.06 | -83.59% | ― | ― | 19.36% | |
42 Neutral | $138.91M | -4.63 | 284.28% | ― | ― | ― | |
42 Neutral | $3.53M | -0.15 | ― | ― | ― | 76.55% |
* Healthcare Sector Average
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NeOnc Technologies Holdings, Inc. Corporate Events
Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresPrivate Placements and FinancingProduct-Related Announcements
NeOnc Advances Glioma Programs and Strengthens Financial Position
Positive
May 18, 2026
In the first quarter of 2026, NeOnc Technologies Holdings, Inc. reported completing the Phase 1 dose-escalation study of NEO212 and setting 610 mg as the recommended Phase 2 dose, with early signs of efficacy in heavily pretreated recurrent gliobl...
Business Operations and StrategyPrivate Placements and Financing
NeOnc Raises Capital Through Private Equity Offerings
Positive
Apr 24, 2026
Between January 29 and April 20, 2026, NeOnc Technologies Holdings, Inc. executed a series of four securities purchase agreements to issue common stock and accompanying five-year warrants at per-share prices of $7.20 and $9.00, respectively. Acros...
Business Operations and StrategyFinancial DisclosuresPrivate Placements and Financing
NeOnc CEO Increases Stake Amid Advancing CNS Cancer Programs
Positive
Apr 16, 2026
On April 14, 2026, NeOnc Technologies Holdings, Inc. reported that Chairman and CEO Amir Heshmatpour bought roughly $300,000 of company stock in the prior week, signaling management’s confidence as it approaches key milestones for its CNS ca...
Private Placements and FinancingRegulatory Filings and Compliance
NeOnc Technologies Launches $75 Million ATM Equity Program
Neutral
Apr 10, 2026
On April 10, 2026, NeOnc Technologies Holdings, Inc. entered into an Equity Distribution Agreement with BTIG, LLC and A.G.P./Alliance Global Partners to establish an at-the-market equity program allowing the company to sell up to $75 million of it...
Business Operations and StrategyExecutive/Board ChangesFinancial DisclosuresPrivate Placements and Financing
NeOnc Technologies Reports Q4 Results and Trial Progress
Neutral
Apr 3, 2026
NeOnc Technologies reported Q4 and full-year 2025 results on April 1, 2026, highlighting completion of the Phase 1 trial for NEO212 with a recommended Phase 2 dose of 610 mg and early signs of anti-tumor activity in recurrent glioblastoma and brai...
Business Operations and StrategyPrivate Placements and Financing
NeOnc Announces New Private Placement to Support Liquidity
Neutral
Mar 23, 2026
NeOnc Technologies Holdings, Inc. has been executing a series of private securities offerings since January 29, 2026, issuing common stock and five-year warrants at fixed prices of $7.20 and $9.00, respectively. The first Securities Purchase Agree...
Business Operations and StrategyExecutive/Board ChangesRegulatory Filings and Compliance
NeOnc Technologies Appoints New Chief Accounting Officer
Positive
Mar 17, 2026
On March 12, 2026, NeOnc Technologies Holdings, Inc. appointed David Choi as Chief Accounting Officer and entered into an employment agreement granting him a $162,500 annual base salary and 170,000 restricted shares, with time-based and performanc...
Business Operations and StrategyProduct-Related Announcements
NeOnc Reports Phase 1 NEO212 Results, Sets Phase 2 Dose
Positive
Mar 6, 2026
On March 4, 2026, NeOnc Technologies reported Phase 1 dose-escalation results from its Phase 1/2 clinical trial of NEO212, its novel oral bio-conjugated therapy for recurrent glioblastoma and brain metastases. The company said the Maximum Tolerate...
Business Operations and StrategyLegal Proceedings
NeOnc Technologies Settles Fox Infused Dispute With Payment
Positive
Mar 4, 2026
On July 1, 2022, NeOnc Technologies, Inc., a subsidiary of NeOnc Technologies Holdings, Inc., entered into an Intellectual Property License and Supply Agreement with Fox Infused, LLC, under which NeOnc agreed to supply certain products and license...
Private Placements and Financing
NeOnc Technologies Completes Late-February Private Equity Offerings
Positive
Mar 4, 2026
NeOnc Technologies Holdings, Inc. completed a series of private securities offerings in early 2026, issuing common stock and five-year warrants under securities purchase agreements dated January 29 and February 24, 2026. The initial January agreem...
Business Operations and StrategyProduct-Related Announcements
NeOnc to Present Initial NEO212 Phase 1 Data
Positive
Feb 27, 2026
On February 27, 2026, NeOnc Technologies Holdings, Inc. announced it will host an investor conference call and webcast on March 4, 2026, to present initial data from the Phase 1 dose-escalation portion of its NEO212-01 Phase 1/2 clinical trial. Th...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
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