Strong Top-Line Growth
Total Q1 revenue of $65.8M, up 41% year-over-year; base business revenue (ex-COVID CleanCap) up 10% YoY.
TriLink Outperformance
TriLink revenue grew 65% YoY (base business growth 15% ex-CleanCap), represented 72% of total revenue (64% ex-CleanCap) and generated $17.3M of adjusted EBITDA (improvement of >$26M YoY).
Profitability and Margin Expansion
Adjusted gross margin of 65.3% and adjusted EBITDA of $20.3M in Q1, exceeding expectations and improving by more than $30M YoY.
Cash Flow and Balance Sheet Progress
Generated $4.2M of positive free cash flow (first positive FCF since Q3 2024); quarter-end cash of $165.9M and a voluntary $50M debt prepayment (long-term debt $242.9M post-payment).
Substantially Raised Full-Year Guidance
Raised 2026 revenue guidance to $205M–$215M (growth of 10%–16% vs 2025) and substantially increased adjusted EBITDA guidance to $30M–$32M (improvement of $61M–$63M YoY).
Product and Commercial Momentum
ModTail adoption surpassing 70 customers with repeat orders; GMP funnel strength with GMP customers expected to grow 22% in 2026 (nine RUO→GMP conversions, two already converted).
R&D and IP Progress
TriLink GMP facility completed with GMP enzymes expected to launch this quarter; ModTail GMP expected later in 2026; two additional European patents for TriLink and a new U.S. patent for Cygnus MVP granted in Q1.
Cygnus Profitability
Cygnus generated $13.6M of adjusted EBITDA with strong margins of 73.8%; continued market role with a 100% attach rate supporting safety testing of all 29 FDA/EMA-approved CAR T/gene therapies.
Operational Efficiency Realized
Restructuring actions now expected to deliver >$65M in annual EBITDA savings; digital/e-commerce channel achieved record website revenue and improved order conversion and efficiency.