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Mediwound (MDWD)
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Mediwound (MDWD) AI Stock Analysis

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MDWD

Mediwound

(NASDAQ:MDWD)

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Neutral 43 (OpenAI - 4o)
Rating:43Neutral
Price Target:
$16.50
▼(-4.13% Downside)
Mediwound's overall stock score is primarily impacted by its challenging financial performance, characterized by ongoing losses and negative cash flows. Technical analysis indicates a bearish trend, further weighing down the score. Valuation metrics are unfavorable due to negative earnings and the absence of dividends. While the earnings call provided some positive insights into future growth potential, these are overshadowed by current financial and operational challenges.
Positive Factors
Manufacturing Expansion
The expanded manufacturing facility enhances Mediwound's ability to meet global demand, supporting long-term growth and market presence.
Revenue Growth
Strong revenue growth indicates successful market penetration and product adoption, bolstering financial stability and future prospects.
Clinical Trial Progress
Advancements in clinical trials for EscharEx could lead to new market opportunities and revenue streams, enhancing long-term growth potential.
Negative Factors
Operating Losses
Rising operating losses indicate financial strain, potentially impacting future investments and operational flexibility.
Cash Flow Challenges
Persistent negative cash flows can limit Mediwound's ability to fund growth initiatives and maintain financial health.
Regulatory Uncertainty
Regulatory challenges in the EU could delay clinical trials, affecting timelines for product development and market entry.

Mediwound (MDWD) vs. SPDR S&P 500 ETF (SPY)

Mediwound Business Overview & Revenue Model

Company DescriptionMediWound Ltd., a biopharmaceutical company, develops, manufactures, and commercializes novel and bio-therapeutic solutions for tissue repair and regeneration. It markets NexoBrid, a biopharmaceutical product for the removal of eschar, a dead or damaged tissue in adults with deep partial- and full-thickness thermal burns to burn centers and hospitals burn units. The company also develops EscharEx, which has completed Phase II clinical trials for the debridement of chronic and other hard-to-heal wounds; MW005, which is in phase I/II for the treatment of low-risk basal cell carcinoma. MediWound Ltd. was founded in 2000 and is headquartered in Yavne, Israel.
How the Company Makes MoneyMediwound generates revenue primarily through the sale of its medical products, most notably NexoBrid. The company sells its products directly to hospitals and healthcare facilities, often through partnerships with distributors and medical supply companies. Additionally, Mediwound may enter into licensing agreements or collaborations with larger pharmaceutical companies that can help enhance its market reach. The company also explores government and institutional contracts, which can provide significant revenue opportunities. Furthermore, Mediwound has been actively involved in clinical trials and research initiatives, which can lead to future product developments and expansions into new markets, thereby contributing to its overall revenue growth.

Mediwound Earnings Call Summary

Earnings Call Date:Nov 20, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted significant advancements in clinical trials and manufacturing capabilities, as well as strong revenue growth. However, these were offset by increased operating losses and uncertainties related to government contracts and clinical trial timelines.
Q3-2025 Updates
Positive Updates
Progress in EscharEx VLU Trial
Enrollment in the VALUE Phase III trial for EscharEx, targeting venous leg ulcers, is advancing with strong support from previous Phase II results. The trial's co-primary endpoints include complete debridement and wound closure.
Expansion of NexoBrid Manufacturing
MediWound completed the commissioning of an expanded NexoBrid manufacturing facility, increasing production capacity by six times, aiming to meet rising global demand.
Financial Strengthening
The balance sheet was strengthened with $30 million of equity financing, increasing cash reserves to $60 million as of September 30, 2025.
Revenue Growth
Revenue for the third quarter was $5.4 million, a 23% increase year-over-year, driven by higher development services revenue.
NexoBrid U.S. Market Performance
NexoBrid achieved record quarterly revenue in the U.S., with a 38% year-over-year increase and 26% sequential growth.
Negative Updates
Increased Operating Loss
Operating loss for the third quarter increased to $6.5 million from $5.1 million in the same period of 2024, due to increased R&D and SG&A expenses.
Uncertainty in BARDA Contract
The government shutdown caused delays in BARDA-related activities, creating uncertainty around the timing of related revenue.
High R&D Expenses
R&D expenses increased to $3.5 million in the third quarter, reflecting higher investment in the EscharEx VALUE Phase III study.
Challenges in EU Site Activation
Some EU sites for the EscharEx trial required additional adjustments to meet regulatory requirements, potentially impacting the study timeline.
Company Guidance
During the third quarter of 2025, MediWound provided comprehensive guidance on its strategic objectives and financial performance. The company is advancing its EscharEx program, targeting $831 million in potential annual peak sales, driven by positive market access assessments and expected shifts in reimbursement policies. MediWound is also progressing with the VALUE Phase III trial for venous leg ulcers, aiming for 216 patients across 40 sites, and plans to start a diabetic foot ulcer study in the second half of 2026. NexoBrid's manufacturing capacity has expanded sixfold, enhancing MediWound's ability to meet global demand. Financially, the company reported a 23% year-over-year revenue increase to $5.4 million for the quarter, supported by higher development services revenue and an improved gross margin of 16.5%. Operating loss increased to $6.5 million, while net loss improved to $2.7 million. The company strengthened its balance sheet with $60 million in cash after completing a $30 million equity financing, positioning it well for future growth.

Mediwound Financial Statement Overview

Summary
Mediwound is facing significant financial challenges, characterized by ongoing losses, negative profit margins, and cash flow difficulties. While there is some revenue growth, the company struggles to convert this into profitability. The balance sheet shows manageable leverage, but the overall financial health is weak due to persistent losses and limited equity growth.
Income Statement
45
Neutral
Mediwound's income statement reveals a challenging financial position with consistent net losses and negative profit margins. The TTM data shows a slight revenue growth rate of 5.41%, but the company continues to struggle with profitability, as evidenced by negative EBIT and EBITDA margins. Gross profit margin has improved slightly over the previous year, but remains low at 18.43%. Overall, the company faces significant challenges in achieving profitability.
Balance Sheet
50
Neutral
The balance sheet indicates a moderate debt-to-equity ratio of 0.40, suggesting manageable leverage. However, the return on equity is negative, reflecting ongoing losses and a weak equity position. The equity ratio is not explicitly provided, but the overall financial health appears strained due to recurring losses and limited equity growth.
Cash Flow
40
Negative
Cash flow analysis shows negative operating and free cash flows, with a declining free cash flow growth rate of -6.46% in the TTM period. The operating cash flow to net income ratio is negative, indicating cash flow challenges. Despite a free cash flow to net income ratio above 1, the overall cash flow situation remains concerning due to persistent negative cash flows.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue20.93M20.22M18.69M26.50M23.76M21.76M
Gross Profit3.88M1.78M2.95M12.32M8.14M7.01M
EBITDA-10.93M-28.12M-4.89M-18.09M-12.12M-7.99M
Net Income-20.60M-30.22M-6.72M-19.60M-13.55M-9.20M
Balance Sheet
Total Assets94.42M73.50M66.46M50.02M19.74M31.07M
Cash, Cash Equivalents and Short-Term Investments59.09M43.16M41.54M33.90M11.05M21.58M
Total Debt9.33M6.93M6.35M846.00K1.39M1.74M
Total Liabilities34.98M42.34M34.86M39.10M24.33M23.80M
Stockholders Equity50.16M31.15M31.59M10.91M-4.58M7.27M
Cash Flow
Free Cash Flow-18.02M-19.90M-16.93M-12.44M-9.40M-7.82M
Operating Cash Flow-14.10M-13.62M-10.46M-11.88M-8.92M-6.89M
Investing Cash Flow10.12M-8.40M-34.32M-481.00K3.55M17.39M
Financing Cash Flow31.60M19.39M22.92M35.76M-1.05M-629.00K

Mediwound Technical Analysis

Technical Analysis Sentiment
Negative
Last Price17.21
Price Trends
50DMA
18.09
Negative
100DMA
18.19
Negative
200DMA
18.31
Negative
Market Momentum
MACD
-0.17
Positive
RSI
43.42
Neutral
STOCH
39.81
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For MDWD, the sentiment is Negative. The current price of 17.21 is below the 20-day moving average (MA) of 17.91, below the 50-day MA of 18.09, and below the 200-day MA of 18.31, indicating a bearish trend. The MACD of -0.17 indicates Positive momentum. The RSI at 43.42 is Neutral, neither overbought nor oversold. The STOCH value of 39.81 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for MDWD.

Mediwound Risk Analysis

Mediwound disclosed 58 risk factors in its most recent earnings report. Mediwound reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Mediwound Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
$355.36M-5.58-29.83%-40.26%
46
Neutral
$370.83M-153.37%24.05%-169.73%
43
Neutral
$222.45M-48.83%6.15%34.52%
41
Neutral
$566.59M-45.35%36.65%
35
Underperform
$114.88M-95.49%72.35%
33
Underperform
$109.19M-3.04-234.46%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
MDWD
Mediwound
17.35
-0.72
-3.98%
LCTX
Lineage Therap
1.61
1.04
182.46%
ELDN
Eledon Pharmaceuticals
1.48
-2.88
-66.06%
DSGN
Design Therapeutics
9.77
3.59
58.09%
VTYX
Ventyx Biosciences
7.94
5.43
216.33%
TVGN
Tevogen Bio Holdings
0.38
-0.67
-63.81%

Mediwound Corporate Events

MediWound Announces Q3 2025 Financial Results and Facility Expansion
Nov 20, 2025

On November 20, 2025, MediWound Ltd. announced its third-quarter financial results, highlighting a 23% year-over-year revenue increase to $5.4 million. The company completed the commissioning of its expanded NexoBrid manufacturing facility, expected to reach full operational capacity by the end of 2025, significantly boosting production to meet global demand. The ongoing VALUE Phase III trial of EscharEx is progressing well, with a peak sales opportunity estimated at $831 million. MediWound also strengthened its balance sheet with $30 million in equity financing, supporting its development and commercialization efforts.

MediWound Raises $30 Million Through Share Offering to Boost EscharEx® Initiatives
Sep 30, 2025

On September 29, 2025, MediWound Ltd. entered into a securities purchase agreement for the sale of 1,734,105 ordinary shares at $17.30 per share, generating approximately $30 million in gross proceeds. The offering closed on September 30, 2025, and the funds are intended to support the pre-commercial activities of EscharEx®, enhance manufacturing capabilities, and for general corporate purposes. H.C. Wainwright & Co., LLC acted as the exclusive placement agent, receiving a transaction fee and additional allowances. This financial move is expected to bolster MediWound’s operational capacity and market positioning in the biotechnology sector.

MediWound Announces $30 Million Direct Offering to Boost Operations
Sep 29, 2025

On September 29, 2025, MediWound Ltd. announced a $30 million registered direct offering of ordinary shares, led by a U.S.-based mutual fund and other healthcare investors. The offering, expected to close on or about September 30, 2025, aims to support the pre-commercial activities of EscharEx, enhance manufacturing capabilities, and fund general corporate purposes, potentially strengthening MediWound’s market position and operational capacity.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 22, 2025