Lyell Immunopharma (LYEL)
NASDAQ:LYEL
Lisocabtagene Maraleucel, Rondecabtagene Autoleucel, Axicabtagene Ciloleucel
Diffuse Large B Cell Lymphoma (Dlbcl), Lymphoma, B-Cell, Large B-Cell Lymphoma, Non-Hodgkin Lymphoma Refractory/ Relapsed, Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma Refractory, Diffuse Large B Cell Lymphoma Relapsed
Phase III
Recruiting
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Sep 16, 2025
Impt-514
Lupus Nephritis, Systemic Lupus Erythematosus
Phase I/II
Withdrawn
A Study of IMPT-514 in Active Refractory Lupus Nephritis (LN) and Systemic Lupus Erythematosus (SLE)
Nov 22, 2023
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Lyl845
Colorectal Cancer, Non-small Cell Lung Cancer, Melanoma
Phase I
Terminated
A Study to Investigate LYL845 in Adults With Solid Tumors
Oct 06, 2022
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Gcc19cart
Colorectal Cancer
Phase I
Recruiting
GCC19CART for Patients With Metastatic Colorectal Cancer
Mar 23, 2022
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Lyl797
Fallopian Tube Cancer, Endometrial Cancer, Non-small Cell Lung Cancer, Primary Peritoneal Carcinoma, Ovarian Cancer, Advanced Breast Cancer, Non Small Cell Lung Cancer, Nsclc Stage Iv, Non Small Cell Lung Cancer Metastatic, Triple Negative Breast Cancer, Nsclc, Ovarian Epithelial Cancer, Relapsed Cancer, Recurrent Breast Cancer, Tnbc - Triple-Negative Breast Cancer, Non-Small Cell Carcinoma Of Lung, Tnm Stage 4, Advanced Lung Carcinoma, Nsclc, Recurrent, Relapse/Recurrence, Recurrent Nsclc, Platinum-Resistant Ovarian Cancer, Endometrioid Tumor, High Grade Serous Carcinoma
Phase I
Terminated
A Study to Investigate LYL797 in Adults With Solid Tumors
Feb 18, 2022
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FAQ
What are the FDA phases for drug approval?
The FDA approval process for new drugs is divided into several phases:
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
a. Preclinical testing
b. Phase 1 – Safety and dosage
c. Phase 2 – Effectiveness and side effects
d. Phase 3 – Confirmation of effectiveness, monitoring of adverse reactions, and comparison with existing treatments
e. Phase 4 – Post-marketing studies to track long-term safety and effectiveness
What is a clinical trial?
A clinical trial is a carefully designed study in which researchers test a drug, treatment, or medical device in people to evaluate its safety, effectiveness, and potential side effects. These trials are essential for determining whether a new treatment should be approved for widespread use.
What drugs does Lyell Immunopharma (LYEL) have in its pipeline
LYEL is currently developing the following drugs: Lisocabtagene Maraleucel, Rondecabtagene Autoleucel, Axicabtagene Ciloleucel, Impt-514, Cyclophosphamide, Fludarabine, Lyl314. These drug candidates are in various stages of clinical development as the company works toward FDA approval.