Top-line Growth and Upgraded 2026 Revenue Guidance
Consolidated revenue of $362 million in Q1 2026, up 11% year-over-year on a constant currency basis; updated full-year 2026 revenue growth guidance increased to 7%–8% from 6%–7%.
Cardiopulmonary Segment Strength
Cardiopulmonary revenue of $209 million in Q1, up 14% year-over-year; heart-lung machine (HLM) revenue grew in the high teens and consumables grew in the mid-teens; full-year cardiopulmonary revenue guidance raised to 8.5%–9.5% (from 7%–8%).
Essenz Upgrade Momentum and Manufacturing Upside
Essenz penetration expected to represent ~80% of annual HLM placements in 2026 vs ~55% in 2025; company expects manufacturing output to increase low double-digits in 2026 and plans new manufacturing line to go live in H2 2026 to accelerate oxygenator output.
Epilepsy Business Acceleration and Reimbursement Win
Epilepsy revenue increased 8% year-over-year (Europe & RoW +12%, U.S. +7%); U.S. Medicare outpatient payments for VNS therapy increased ~48% for new patient implants and ~47% for end-of-service procedures effective Jan 1, 2026; full-year epilepsy revenue guidance raised to 6%–7% (from 5.5%–6.5%).
Regulatory and Clinical Milestones in OSA
Received FDA PMA for the aura6000 system (first FDA-approved HGNS device without CCC-related contraindication or warning); full 12-month OSPREY RCT results published in Annals of Internal Medicine demonstrating clinically meaningful and sustained improvements.
PolySync Efficacy and Clinical Differentiation
PolySync titration algorithm converted over 50% of OSPREY nonresponders into responders; cumulative responder rate approaching ~80% across the OSPREY population following PolySync, strengthening competitive positioning ahead of launch.
Improved Profitability Metrics and EPS Upgrade
Adjusted operating income of $71 million in Q1 (vs $65 million prior year); adjusted operating margin ~20% in Q1 and full-year margin forecast 20%–21%; adjusted diluted EPS $0.98 in Q1 vs $0.88 prior year; 2026 adjusted diluted EPS guidance raised to $4.20–$4.30 (approx. 9% growth at midpoint).
Balance Sheet Improvements and Debt Reduction
Cash balance $540 million and total debt $288 million as of March 31, 2026 (debt reduced from $377 million at year-end 2025) following early repayment of $98 million in term facilities.