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Kezar Life Sciences Inc (KZR)
NASDAQ:KZR

Kezar Life Sciences (KZR) AI Stock Analysis

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KZR

Kezar Life Sciences

(NASDAQ:KZR)

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Neutral 56 (OpenAI - 5.2)
Rating:56Neutral
Price Target:
$7.50
▲(1.35% Upside)
Action:ReiteratedDate:04/04/26
The score is held down primarily by weak financial fundamentals (ongoing losses, negative free cash flow, and equity erosion). Offsetting this are constructive technical trend signals and a positive M&A-driven catalyst, while valuation remains constrained by negative earnings and no dividend.
Positive Factors
Low leverage and improving balance sheet
Kezar’s sharply reduced debt and low debt-to-equity (around 0.03) materially lower financial risk for a clinical-stage biotech. This structural balance-sheet strength preserves strategic optionality, reduces interest burdens, and lengthens runway flexibility versus highly levered peers.
Negative Factors
Persistent negative cash flow and cash burn
Consistent negative operating and free cash flow forces reliance on external financing, increasing dilution and execution risk. Although 2025 shows improvement, recurring cash burn is structural for a clinical-stage biopharma and limits ability to self-fund trials or scale operations without partners or capital raises.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage and improving balance sheet
Kezar’s sharply reduced debt and low debt-to-equity (around 0.03) materially lower financial risk for a clinical-stage biotech. This structural balance-sheet strength preserves strategic optionality, reduces interest burdens, and lengthens runway flexibility versus highly levered peers.
Read all positive factors

Kezar Life Sciences (KZR) vs. SPDR S&P 500 ETF (SPY)

Kezar Life Sciences Business Overview & Revenue Model

Company Description
Kezar Life Sciences, Inc., a clinical-stage biotechnology company, engages in the discovery and development of novel small molecule therapeutics to treat unmet needs in immune-mediated diseases and cancer in the United States. The company's lead p...
How the Company Makes Money
Kezar Life Sciences does not primarily generate revenue from product sales because it is a clinical-stage biotechnology company without commercialized therapies. The company has historically funded operations mainly through financing activities su...

Kezar Life Sciences Financial Statement Overview

Summary
Development-stage profile with minimal/inconsistent revenue and persistent losses plus structurally negative operating/free cash flow. Offsetting positives are improving 2025 loss and cash-burn trends and very low leverage, but multi-year equity erosion signals ongoing financing and execution risk.
Income Statement
18
Very Negative
Balance Sheet
46
Neutral
Cash Flow
22
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.007.00M0.000.00
Gross Profit-897.00K-1.04M7.00M0.00-1.51M
EBITDA-51.37M-81.10M-99.25M-66.03M-52.96M
Net Income-56.03M-83.74M-101.87M-68.24M-54.63M
Balance Sheet
Total Assets76.65M144.68M221.24M299.57M217.93M
Cash, Cash Equivalents and Short-Term Investments71.88M132.25M201.37M276.56M208.35M
Total Debt2.33M16.18M18.93M21.26M14.04M
Total Liabilities6.57M27.77M33.66M29.70M21.06M
Stockholders Equity70.07M116.92M187.57M269.87M196.88M
Cash Flow
Free Cash Flow-51.78M-74.24M-83.45M-60.42M-42.75M
Operating Cash Flow-51.78M-74.21M-81.64M-58.85M-42.44M
Investing Cash Flow92.46M80.43M76.05M-91.39M-28.44M
Financing Cash Flow-10.59M103.00K638.00K127.86M112.58M

Kezar Life Sciences Technical Analysis

Technical Analysis Sentiment
Positive
Last Price7.40
Price Trends
50DMA
6.61
Positive
100DMA
6.43
Positive
200DMA
5.43
Positive
Market Momentum
MACD
0.14
Negative
RSI
64.02
Neutral
STOCH
90.25
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KZR, the sentiment is Positive. The current price of 7.4 is above the 20-day moving average (MA) of 6.87, above the 50-day MA of 6.61, and above the 200-day MA of 5.43, indicating a bullish trend. The MACD of 0.14 indicates Negative momentum. The RSI at 64.02 is Neutral, neither overbought nor oversold. The STOCH value of 90.25 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for KZR.

Kezar Life Sciences Risk Analysis

Kezar Life Sciences disclosed 63 risk factors in its most recent earnings report. Kezar Life Sciences reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Kezar Life Sciences Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$54.55M-0.82-62.53%35.80%
56
Neutral
$83.78M-2.64-291.42%61.23%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
43
Neutral
$26.71M-2.94-108.76%-100.00%33.44%
42
Neutral
$5.06M-0.56-68.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KZR
Kezar Life Sciences
7.40
3.05
70.11%
AKTX
Akari Therapeutics
4.47
-41.93
-90.37%
XCUR
Exicure
4.19
-8.61
-67.27%
PYPD
PolyPid
4.39
1.99
82.92%

Kezar Life Sciences Corporate Events

Business Operations and StrategyExecutive/Board Changes
Kezar Life Sciences Announces Major Executive Leadership Changes
Negative
Apr 3, 2026
On April 1, 2026, Kezar Life Sciences terminated its lease for 48,714 square feet of office space at 4000 Shoreline Court in San Francisco, two months before its original July 31, 2026 expiry. The company agreed to pay roughly $2 million to the la...
Business Operations and StrategyM&A Transactions
Kezar Life Sciences to Be Acquired by Aurinia
Positive
Mar 30, 2026
On March 30, 2026, Kezar Life Sciences agreed to be acquired by Aurinia Pharmaceuticals in a cash-and-CVR transaction structured as a tender offer and follow-on merger. Aurinia will pay $6.955 per Kezar share in cash plus a non-transferable contin...
Business Operations and StrategyM&A Transactions
Kezar Divests Sec61 Program to Refocus on Core Pipeline
Positive
Mar 12, 2026
On March 6, 2026, Kezar Life Sciences agreed to sell its Sec61-based discovery and development program, including preclinical candidate KZR-261, to Enodia Therapeutics in an asset deal under which Enodia assumed related liabilities but did not acq...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 04, 2026