Financial PerformanceKezar Life Sciences reported a net loss of $2.78 per share in 3Q24, which is wider than the forecasted net loss of $0.23 per share.
Regulatory ChallengesA partial clinical hold has been placed on Phase 2a of zetomipzomib in autoimmune hepatitis by the FDA, adding uncertainty to the program.
Safety ConcernsThe IDMC recommended the suspension of enrollment and dosing in PALIZADE after their recent review of emerging safety data, including an assessment of four Grade 5 (fatal) serious adverse events (SAEs).