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Aligos Therapeutics (ALGS)
NASDAQ:ALGS
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Aligos Therapeutics (ALGS) AI Stock Analysis

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ALGS

Aligos Therapeutics

(NASDAQ:ALGS)

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Underperform 39 (OpenAI - 4o)
Rating:39Underperform
Price Target:
$8.50
▼(-13.79% Downside)
Aligos Therapeutics' stock score is primarily impacted by its poor financial performance, characterized by declining revenues and persistent losses. The technical analysis suggests bearish momentum, and the valuation metrics indicate significant risks due to negative earnings. These factors collectively result in a low overall stock score.
Positive Factors
Positive Clinical Data
The positive clinical data on pevifoscorvir sodium indicates promising therapeutic potential, enhancing Aligos's competitive position in liver disease treatment.
Pipeline Progress
Successful enrollment in the Phase 2 study suggests robust pipeline progress, which is crucial for long-term growth and potential future revenue streams.
Low Leverage
Maintaining low leverage provides financial flexibility, allowing Aligos to invest in R&D and strategic initiatives without significant debt burden.
Negative Factors
Negative Cash Flow
Negative cash flow indicates potential liquidity issues, limiting the company's ability to fund operations and invest in growth without external financing.
Declining Revenue
Declining revenue growth reflects challenges in market penetration and sales, which could hinder long-term financial health and operational sustainability.
Consistent Losses
Ongoing losses highlight operational inefficiencies and profitability challenges, which may impact the company's ability to achieve financial stability.

Aligos Therapeutics (ALGS) vs. SPDR S&P 500 ETF (SPY)

Aligos Therapeutics Business Overview & Revenue Model

Company DescriptionAligos Therapeutics (ALGS) is a biotechnology company focused on developing innovative therapies for viral infections and liver diseases. The company primarily operates in the biopharmaceutical sector, with a particular emphasis on hepatitis B and other liver-related conditions. Aligos is known for its proprietary technology platforms that facilitate the discovery and development of novel therapeutics aimed at addressing unmet medical needs in these areas.
How the Company Makes MoneyAligos Therapeutics generates revenue through several key streams. Primarily, the company engages in research and development collaborations with larger pharmaceutical companies, which may include upfront payments, milestone payments based on the achievement of specific clinical or regulatory objectives, and royalties on future sales of products developed from these partnerships. Additionally, Aligos may receive funding from government grants or awards aimed at supporting innovative research in the biotech space. The company may also generate revenue through the licensing of its proprietary technologies or drug candidates to other firms in exchange for fees and royalties, enhancing its financial stability and growth prospects.

Aligos Therapeutics Financial Statement Overview

Summary
Aligos Therapeutics faces significant financial challenges, with declining revenues, persistent losses, and negative cash flows. While the company maintains low leverage, its inability to generate profits and positive cash flow raises concerns about its financial sustainability.
Income Statement
30
Negative
Aligos Therapeutics shows a declining revenue trend with a negative revenue growth rate of -16.64% in the TTM. The company has consistently negative net profit margins, indicating ongoing losses. The EBIT and EBITDA margins are also negative, reflecting operational inefficiencies. Overall, the income statement highlights significant challenges in achieving profitability.
Balance Sheet
40
Negative
The balance sheet shows a relatively low debt-to-equity ratio of 0.08 in the TTM, indicating low leverage. However, the return on equity is negative, reflecting the company's inability to generate profits from its equity base. The equity ratio is not explicitly calculated, but the available data suggests a moderate level of equity relative to total assets.
Cash Flow
35
Negative
The cash flow statement reveals a slight improvement in free cash flow growth at 5.87% in the TTM, but operating cash flow remains negative, indicating cash burn. The free cash flow to net income ratio is slightly above 1, suggesting that free cash flow is marginally better than net income, but overall cash flow health is weak.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue2.65M3.94M15.53M13.91M4.36M0.00
Gross Profit2.39M3.94M15.53M13.91M4.36M-3.33M
EBITDA-84.83M-86.53M-85.06M-93.91M-124.54M-105.06M
Net Income-86.46M-131.21M-87.68M-96.05M-128.33M-108.54M
Balance Sheet
Total Assets109.76M70.09M151.53M146.69M235.37M265.30M
Cash, Cash Equivalents and Short-Term Investments99.10M56.94M135.70M125.83M190.73M243.51M
Total Debt6.07M8.38M11.14M12.57M14.46M13.01M
Total Liabilities37.93M99.07M59.45M42.79M50.64M45.26M
Stockholders Equity71.83M-28.97M92.08M103.90M184.73M220.04M
Cash Flow
Free Cash Flow-79.53M-80.87M-79.02M-80.33M-116.55M-76.33M
Operating Cash Flow-79.16M-80.74M-79.00M-79.39M-115.66M-74.26M
Investing Cash Flow-15.83M-18.28M44.98M-26.29M3.02M32.76M
Financing Cash Flow101.61M355.00K88.33M164.00K78.68M192.35M

Aligos Therapeutics Technical Analysis

Technical Analysis Sentiment
Positive
Last Price9.86
Price Trends
50DMA
9.03
Positive
100DMA
9.11
Positive
200DMA
8.91
Positive
Market Momentum
MACD
0.18
Negative
RSI
61.57
Neutral
STOCH
92.49
Negative
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ALGS, the sentiment is Positive. The current price of 9.86 is above the 20-day moving average (MA) of 7.82, above the 50-day MA of 9.03, and above the 200-day MA of 8.91, indicating a bullish trend. The MACD of 0.18 indicates Negative momentum. The RSI at 61.57 is Neutral, neither overbought nor oversold. The STOCH value of 92.49 is Negative, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for ALGS.

Aligos Therapeutics Risk Analysis

Aligos Therapeutics disclosed 91 risk factors in its most recent earnings report. Aligos Therapeutics reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aligos Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
42
Neutral
$31.60M-62.30%-100.00%-26.30%
40
Underperform
$45.91M-0.54-15.81%-113.06%
39
Underperform
$44.35M-0.36-141.82%-55.88%6.14%
36
Underperform
$74.47M-50.23%21.17%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ALGS
Aligos Therapeutics
9.58
-16.14
-62.75%
MNOV
Medicinova
1.45
-0.93
-39.08%
CELU
Celularity
2.00
0.03
1.52%
BRNS
Barinthus Biotherapeutics
0.79
-0.19
-19.55%
GNTA
Genenta Science SpA Sponsored ADR
2.01
-3.29
-62.08%
ACRV
Acrivon Therapeutics, Inc.
2.36
-5.08
-68.28%

Aligos Therapeutics Corporate Events

Aligos Therapeutics Reports Q3 2025 Progress and Financials
Nov 7, 2025

Aligos Therapeutics, Inc. is a clinical-stage biotechnology company focused on developing therapies for liver and viral diseases, leveraging its scientific expertise to address unmet medical needs such as chronic hepatitis B virus infection and metabolic dysfunction-associated steatohepatitis.

Aligos Therapeutics’ Promising Hepatitis B Study: A Potential Game-Changer?
Oct 27, 2025

Study Overview: Aligos Therapeutics, Inc. is conducting a Phase 2 study titled ‘A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg-Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)’. The study aims to assess the efficacy and safety of ALG-000184, a potential new treatment for chronic Hepatitis B, compared to the existing treatment, Tenofovir Disoproxil Fumarate (TDF). This study is significant as it could lead to improved treatment options for patients with chronic Hepatitis B.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 22, 2025