The score is primarily held back by weak financial performance driven by large losses and heavy cash burn despite strong revenue growth and a debt-free balance sheet. Technicals also lean bearish with the stock below key moving averages and negative MACD, while valuation remains constrained by negative earnings and no dividend support.
Positive Factors
Revenue Growth / Commercial Traction
Sharp, sustained top-line growth indicates the company is converting R&D and go-to-market investments into real sales and early commercial traction. Over a 2–6 month horizon this suggests expanding market acceptance and a clearer path to leverage fixed costs, improving odds of eventual scale efficiencies.
Gross Margin / Unit Economics
A roughly 52% gross margin signals healthy underlying unit economics that can support profitable operations once scale and operating leverage improve. Durable margins reduce the break-even revenue threshold and provide long-term capacity to fund R&D and sales investment without destroying product-level profitability.
Debt-Free Balance Sheet / Financial Flexibility
Zero reported debt and a sizable equity base give the company financial flexibility: no interest burden or covenant pressure and greater optionality to raise capital or invest in growth. Over months this lowers bankruptcy risk and preserves strategic choices for funding commercialization or trials.
Negative Factors
Large Operating and Net Losses
Very large recurring operating and net losses erode equity and indicate the current business model and cost base are not yet self-sustaining. Persisting deficits force continuous external funding, raise execution risk, and lengthen the timeline to profitability unless material cost or revenue inflections occur.
High Cash Burn / Negative Free Cash Flow
Deep negative operating and free cash flow show the company is consuming cash faster than it generates it, creating a tangible runway constraint. Over a multi-month horizon this increases dependency on external financing, raises dilution or refinancing risk, and limits capacity to fund growth without raising capital.
Negative Returns and Dilution Risk
A negative ROE signals that deployed capital is destroying shareholder value to date. Because operations are equity-funded, management may need to issue more shares to sustain growth, risking dilution. Persistently negative returns reduce long-term investor incentives and constrain reinsuring long-term capital.
Cuorips Inc. (4894) vs. iShares MSCI Japan ETF (EWJ)
Market Cap
¥58.96B
Dividend YieldN/A
Average Volume (3M)107.56K
Price to Earnings (P/E)―
Beta (1Y)1.08
Revenue Growth1772.85%
EPS Growth16.16%
CountryJP
Employees59
SectorHealthcare
Sector Strength45
IndustryBiotechnology
Share Statistics
EPS (TTM)-30.15
Shares Outstanding8,273,376
10 Day Avg. Volume98,200
30 Day Avg. Volume107,556
Financial Highlights & Ratios
PEG Ratio16.56
Price to Book (P/B)12.03
Price to Sales (P/S)379.55
P/FCF Ratio-74.48
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)N/A
Revenue Forecast (FY)N/A
Cuorips Inc. Business Overview & Revenue Model
Company DescriptionCuorips Inc. engages in the research, development, manufacture, commercialization, and sale of iPS cell-derived cardiomyocyte sheets. The company offers cellular and tissue-based, and cell processing products. It also provides contract development and manufacturing, and consulting services. The company was formerly known as Cuore Inc. and changed its name to Cuorips Inc. in June 2017. Cuorips Inc. was incorporated in 2017 and is headquartered in Tokyo, Japan.
How the Company Makes MoneyCuorips Inc. generates revenue through the development and commercialization of regenerative medicine products targeting cardiac diseases. The company makes money by licensing its proprietary technologies and therapies to pharmaceutical and biotechnology companies. Additionally, Cuorips Inc. may receive funding through collaborative research agreements and partnerships with healthcare institutions and academic entities. Revenue streams could also include milestone payments and royalties from successfully developed and marketed therapies. The company's earnings are significantly influenced by its ability to advance its pipeline products through clinical trials and secure regulatory approvals.
Cuorips Inc. Financial Statement Overview
Summary
Strong revenue growth and solid gross margin are outweighed by very large operating and net losses and significant negative operating/free cash flow. The debt-free, equity-supported balance sheet provides flexibility, but ongoing burn and negative returns remain key risks.
Income Statement
22
Negative
Revenue has scaled sharply in the latest year (2025 annual revenue up ~404% to ~¥175m), and gross margin remains solid (~52%). However, profitability is very weak: operating losses remain extremely large (EBIT about -¥590m) and net losses deepened to about -¥644m, leaving net margin highly negative. Overall, the company shows early commercial traction but still lacks a clear path to operating breakeven based on the current cost structure.
Balance Sheet
74
Positive
The balance sheet is conservatively levered with zero reported debt and meaningful equity (~¥5.5b) supporting a largely equity-funded profile. That said, returns remain negative (return on equity around -11.7% in 2025), indicating ongoing value dilution risk if losses persist. Overall financial flexibility looks good, but sustained losses continue to pressure long-term capital efficiency.
Cash Flow
25
Negative
Cash generation is weak, with operating cash flow negative and worsening in 2025 (about -¥813m), and free cash flow also deeply negative (about -¥893m), implying a high cash burn profile. Free cash flow is consistently negative relative to net income (free cash flow to net income > 1), suggesting losses are translating into real cash outflows rather than being primarily non-cash. The key strength is consistency of reporting and a lack of debt-related cash burden, but the burn rate remains the central risk.
Breakdown
TTM
Mar 2025
Mar 2024
Mar 2023
Mar 2022
Mar 2021
Income Statement
Total Revenue
260.31M
175.21M
23.10M
38.28M
13.91M
220.00K
Gross Profit
119.12M
91.56M
-60.47M
-57.64M
-82.09M
-73.78M
EBITDA
-511.99M
-513.57M
-518.38M
-371.78M
-280.46M
-207.93M
Net Income
-652.25M
-644.34M
-632.18M
-452.08M
-375.34M
-307.83M
Balance Sheet
Total Assets
5.75B
5.74B
6.18B
3.59B
4.04B
4.36B
Cash, Cash Equivalents and Short-Term Investments
4.85B
4.79B
5.58B
2.94B
3.34B
3.54B
Total Debt
0.00
0.00
0.00
0.00
0.00
0.00
Total Liabilities
324.59M
211.91M
200.96M
133.79M
149.36M
141.95M
Stockholders Equity
5.42B
5.53B
5.98B
3.45B
3.90B
4.22B
Cash Flow
Free Cash Flow
0.00
-892.81M
-474.83M
-412.18M
-249.45M
-950.97M
Operating Cash Flow
0.00
-812.62M
-451.06M
-401.61M
-220.76M
-282.80M
Investing Cash Flow
0.00
-117.99M
-33.50M
-8.97M
-28.44M
-670.21M
Financing Cash Flow
0.00
143.11M
3.12B
10.69M
48.54M
3.77B
Cuorips Inc. Technical Analysis
Technical Analysis Sentiment
Positive
Last Price6230.00
Price Trends
50DMA
7998.00
Negative
100DMA
7121.30
Positive
200DMA
6835.35
Positive
Market Momentum
MACD
-371.26
Positive
RSI
45.61
Neutral
STOCH
44.29
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4894, the sentiment is Positive. The current price of 6230 is below the 20-day moving average (MA) of 7220.50, below the 50-day MA of 7998.00, and below the 200-day MA of 6835.35, indicating a neutral trend. The MACD of -371.26 indicates Positive momentum. The RSI at 45.61 is Neutral, neither overbought nor oversold. The STOCH value of 44.29 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for JP:4894.
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 03, 2026