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Cyfuse Biomedical K.K. (JP:4892)
:4892
Japanese Market
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Cyfuse Biomedical K.K. (4892) AI Stock Analysis

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JP:4892

Cyfuse Biomedical K.K.

(4892)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
¥532.00
▼(-9.83% Downside)
Action:Reiterated
Date:02/18/26
The score is held down primarily by weak financial performance—deep losses and ongoing negative free cash flow—despite a strong revenue rebound and manageable leverage. Technicals are moderately supportive with improving short-to-mid-term trend and constructive momentum, while valuation remains constrained by unprofitability and no dividend yield provided.
Positive Factors
Strong revenue rebound
Revenue surged 253% YoY in 2025 to ~231m, signaling renewed commercial traction for products and services. A durable top-line increase supports scale economies, helps absorb fixed R&D costs, and improves the potential for sustained margin recovery as the business executes commercialization.
Negative Factors
Persistent negative cash flow
Operating cash flow (~-535m) and free cash flow (~-582m) in 2025 show continued cash burn despite revenue growth. Persistent negative cash generation necessitates external financing, raising dilution and refinancing risk and limiting the company's ability to self-fund scaling or endure prolonged R&D cycles.
Read all positive and negative factors
Positive Factors
Negative Factors
Strong revenue rebound
Revenue surged 253% YoY in 2025 to ~231m, signaling renewed commercial traction for products and services. A durable top-line increase supports scale economies, helps absorb fixed R&D costs, and improves the potential for sustained margin recovery as the business executes commercialization.
Read all positive factors

Cyfuse Biomedical K.K. (4892) vs. iShares MSCI Japan ETF (EWJ)

Cyfuse Biomedical K.K. Business Overview & Revenue Model

Company Description
Established in 2010 and headquartered in Tokyo, Japan, Cyfuse Biomedical K.K. focuses on the creation, production, and distribution of regenerative medicine solutions. The company is actively involved in developing cell-based products for therapeu...
How the Company Makes Money
Cyfuse Biomedical makes money primarily by commercializing its 3D cell assembly platform and related offerings to customers engaged in life science research and regenerative medicine development. Revenue is generated through (1) sales of products ...

Cyfuse Biomedical K.K. Financial Statement Overview

Summary
Financials are dominated by very large, persistent losses (2025 EBIT margin ~-359%, net margin ~-331%) and ongoing cash burn (2025 FCF ~-582m) despite a sharp 2025 revenue rebound (+253% YoY). Balance sheet leverage is moderate (debt-to-equity ~0.48), but rising debt and continued losses increase financing risk.
Income Statement
14
Very Negative
Balance Sheet
52
Neutral
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue65.82M231.00M54.45M61.11M374.48M708.25M
Gross Profit-3.23M78.40M1.56M-378.00K223.93M568.20M
EBITDA-883.27M-792.68M-860.12M-659.31M-370.81M89.07M
Net Income-827.55M-763.84M-872.24M-589.21M-473.96M142.91M
Balance Sheet
Total Assets3.23B4.27B3.52B4.21B4.82B2.65B
Cash, Cash Equivalents and Short-Term Investments2.70B3.73B3.05B3.87B4.44B2.41B
Total Debt766.00M1.31B852.80M913.00M857.79M569.06M
Total Liabilities901.89M1.51B975.60M1.01B1.05B746.12M
Stockholders Equity2.33B2.76B2.54B3.20B3.77B1.90B
Cash Flow
Free Cash Flow0.00-581.93M-768.16M-581.77M-631.87M161.54M
Operating Cash Flow0.00-534.79M-760.55M-562.30M-403.60M161.54M
Investing Cash Flow0.00-397.56M-8.64M-19.47M-430.67M-50.58M
Financing Cash Flow0.001.26B-52.01M18.24M2.66B229.21M

Cyfuse Biomedical K.K. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price590.00
Price Trends
50DMA
625.66
Negative
100DMA
634.89
Negative
200DMA
616.02
Negative
Market Momentum
MACD
-27.21
Positive
RSI
32.69
Neutral
STOCH
20.46
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4892, the sentiment is Negative. The current price of 590 is above the 20-day moving average (MA) of 583.20, below the 50-day MA of 625.66, and below the 200-day MA of 616.02, indicating a bearish trend. The MACD of -27.21 indicates Positive momentum. The RSI at 32.69 is Neutral, neither overbought nor oversold. The STOCH value of 20.46 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4892.

Cyfuse Biomedical K.K. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
71
Outperform
¥6.19B9.123.00%-9.59%-25.59%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
¥5.52B27.793.21%1.60%-32.76%
48
Neutral
¥5.42B-6.47246.42%9.39%
42
Neutral
¥6.28B-6.93-90.96%24.62%60.41%
42
Neutral
¥3.28B-1.6614.26%
41
Neutral
¥5.34B-0.80-39.73%-9.00%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4892
Cyfuse Biomedical K.K.
537.00
-376.00
-41.18%
JP:4597
Solasia Pharma KK
23.00
-7.00
-23.33%
JP:4539
Nippon Chemiphar Co., Ltd.
1,528.00
90.87
6.32%
JP:4582
Symbio Pharmaceuticals Limited
70.00
-104.00
-59.77%
JP:4883
Modalis Therapeutics Corporation
34.00
-58.00
-63.04%
JP:7079
WDB coco Co., Ltd.
2,575.00
-336.20
-11.55%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 18, 2026