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Modalis Therapeutics Corporation
(4883)
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Rating:41Neutral
Price Target:
¥32.00
▼(-42.86% Downside)
Action:Reiterated
Date:06/26/26
The score is primarily weighed down by weak financial performance (minimal revenue, large recurring losses, and sustained cash burn) and bearish technical trends (price below key moving averages with negative MACD). Valuation provides little offset because earnings are negative (negative P/E) and no dividend yield is available.
Positive Factors
Proprietary epigenome-modulation platform
Modalis' proprietary epigenome-modulation approach represents a durable scientific differentiation: a platform technology can generate multiple candidates, accelerate discovery, and create sustained R&D optionality. Platform focus supports repeatable pipeline expansion and long-term competitive advantages in specialty biopharma.
Negative Factors
Minimal-to-zero revenue
Sustained absence of meaningful revenue means the business lacks operating cash generation and product-market validation; the company remains fully dependent on external funding to advance programs, which is a durable risk to sustainability and long-term autonomous growth.
Read all positive and negative factors
Positive Factors
Negative Factors
Proprietary epigenome-modulation platform
Modalis' proprietary epigenome-modulation approach represents a durable scientific differentiation: a platform technology can generate multiple candidates, accelerate discovery, and create sustained R&D optionality. Platform focus supports repeatable pipeline expansion and long-term competitive advantages in specialty biopharma.
Read all positive factors
Modalis Therapeutics Corporation (4883) vs. iShares MSCI Japan ETF (EWJ)
Market Cap
¥3.12B
Dividend YieldN/A
Average Volume (3M)719.68K
Price to Earnings (P/E)―
Beta (1Y)0.39
Revenue GrowthN/A
EPS Growth14.26%
CountryJP
Employees17
SectorGeneral
Sector StrengthN/A
IndustryBiotechnology
Share Statistics
EPS (TTM)-22.80
Shares Outstanding104,124,100
10 Day Avg. Volume617,120
30 Day Avg. Volume719,680
Financial Highlights & Ratios
PEG Ratio0.81
Price to Book (P/B)1.55
Price to Sales (P/S)0.00
P/FCF Ratio-2.04
Enterprise Value/Market CapN/A
Enterprise Value/RevenueN/A
Enterprise Value/Gross ProfitN/A
Enterprise Value/EbitdaN/A
Forecast
1Y Price TargetN/A
Price Target UpsideN/A
Rating ConsensusN/A
Number of Analyst Covering0
EPS Forecast (FY)-22.2
Revenue Forecast (FY)¥800.00M
Modalis Therapeutics Corporation Business Overview & Revenue Model
Company Description
Modalis Therapeutics Corporation focuses on discovering and developing treatments for severe genetic conditions. The company utilizes its proprietary CRISPR-GNDM technology to create therapies by controlling gene expression through the epigenetic ...
How the Company Makes Money
null...
Modalis Therapeutics Corporation Financial Statement Overview
Summary
Income Statement
12
Very Negative
Balance Sheet
54
Neutral
Cash Flow
18
Very Negative
| Breakdown | TTM | Dec 2025 | Dec 2024 | Dec 2023 | Dec 2022 | Dec 2021 |
|---|---|---|---|---|---|---|
Income Statement | ||||||
| Total Revenue | 0.00 | 0.00 | 0.00 | 0.00 | 40.50M | 1.10M |
| Gross Profit | -583.00K | 0.00 | 0.00 | -731.00K | -83.17M | 1.10M |
| EBITDA | -1.88B | -2.21B | -2.15B | -2.37B | -2.58B | -667.55M |
| Net Income | -1.82B | -2.15B | -1.32B | -2.39B | -2.70B | -738.96M |
Balance Sheet | ||||||
| Total Assets | 2.94B | 2.96B | 3.69B | 2.03B | 3.13B | 6.07B |
| Cash, Cash Equivalents and Short-Term Investments | 2.81B | 2.81B | 3.58B | 1.88B | 2.93B | 4.94B |
| Total Debt | 0.00 | 0.00 | 0.00 | 412.50M | 0.00 | 0.00 |
| Total Liabilities | 142.55M | 170.94M | 143.47M | 645.50M | 188.60M | 519.92M |
| Stockholders Equity | 2.80B | 2.79B | 3.55B | 1.38B | 2.94B | 5.55B |
Cash Flow | ||||||
| Free Cash Flow | 0.00 | -2.12B | -1.43B | -2.29B | -2.09B | -854.58M |
| Operating Cash Flow | 0.00 | -2.12B | -1.43B | -2.25B | -1.90B | -747.47M |
| Investing Cash Flow | 0.00 | -2.57M | -188.00K | -39.70M | -185.72M | 171.56M |
| Financing Cash Flow | 0.00 | 1.35B | 3.04B | 1.22B | 63.68M | 72.63M |
Modalis Therapeutics Corporation Technical Analysis
Negative
56.00
Price Trends
34.58
Negative
46.78
Negative
55.35
Negative
Market Momentum
-1.39
Negative
45.13
Neutral
31.11
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4883, the sentiment is Negative. The current price of 56 is above the 20-day moving average (MA) of 32.30, above the 50-day MA of 34.58, and above the 200-day MA of 55.35, indicating a bearish trend. The MACD of -1.39 indicates Negative momentum. The RSI at 45.13 is Neutral, neither overbought nor oversold. The STOCH value of 31.11 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4883.
Modalis Therapeutics Corporation Peers Comparison
UnderperformOutperform
Sector (55)
Name | Overall Rating | Market Cap | P/E Ratio | ROE | Dividend Yield | Revenue Growth | EPS Growth |
|---|---|---|---|---|---|---|---|
55 Neutral | $6.65B | 3.83 | -15.92% | 6.20% | 10.91% | 7.18% | |
54 Neutral | ¥5.99B | -48.34 | ― | 3.21% | 0.60% | -131.22% | |
53 Neutral | ¥12.67B | 23.73 | ― | ― | 1.62% | -25.43% | |
44 Neutral | ¥5.23B | -5.79 | ― | ― | 246.42% | 9.39% | |
42 Neutral | ¥7.64B | -7.93 | -54.56% | ― | 24.62% | 60.41% | |
41 Neutral | ¥3.12B | -1.32 | ― | ― | ― | 14.26% | |
41 Neutral | ¥5.53B | -0.65 | ― | ― | -39.73% | -9.00% |
* General Sector Average
JP:4883
Modalis Therapeutics Corporation
32.00
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-64.44%
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Modalis Therapeutics Corporation Corporate Events
Modalis Highlights CRISPR-GNDM Platform as Cornerstone of Rare Disease Growth Strategy
Jul 14, 2026
Modalis Therapeutics has outlined its growth-oriented business plans centered on its CRISPR-GNDM technology platform for rare diseases. The company highlights key attributes of this approach, including long-lasting therapeutic effects over years o...
Modalis Books ¥14 Million in FX Gains, Boosting Quarterly Results
May 13, 2026
Modalis Therapeutics Corporation reported non-operating income of 14 million yen in foreign exchange gains for the three months ended March 31, 2026, driven primarily by the revaluation of its foreign currency-denominated assets and liabilities am...
Modalis outlines conditions and limitations around its Q1 2026 disclosure
May 13, 2026
Modalis Therapeutics has released its business and financial report for the first quarter of 2026, providing an update on its operations and corporate status. The document is positioned as an informational, reference-only English translation of th...
Modalis Narrows Quarterly Loss but Keeps Outlook Uncertain Amid Zero Revenue
May 13, 2026
Modalis Therapeutics reported no operating revenue for the quarter ended March 31, 2026, and narrowed its loss attributable to owners of the parent to ¥323 million from ¥652 million a year earlier. Basic loss per share improved to ¥...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
Disclaimer
This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.