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Medrx Co., Ltd. (JP:4586)
:4586
Japanese Market
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Medrx Co., Ltd. (4586) AI Stock Analysis

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JP:4586

Medrx Co., Ltd.

(4586)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
¥77.00
▼(-31.86% Downside)
Action:ReiteratedDate:04/03/26
The score is held down primarily by heavy ongoing losses and sustained negative cash flow despite strong gross margins and a sharp 2025 revenue rebound. Technicals also detract as the stock trades well below major moving averages with weak momentum, while valuation is constrained by negative earnings and no dividend support.
Positive Factors
Very high gross margins
Sustained 85–90% gross margins indicate attractive unit economics and product-level profitability potential. Over the medium term this margin cushion supports reinvestment in R&D or commercial buildout and offers resilience to input-cost shocks, aiding long-term margin recovery when revenue scales.
Negative Factors
Consistent negative operating and free cash flow
Persistent negative operating and free cash flow means the business is not self-funding and will need external financing or depleting reserves to continue operations. This structural cash burn increases dilution risk, constrains strategic flexibility, and is a core solvency concern if revenue improvement stalls.
Read all positive and negative factors
Positive Factors
Negative Factors
Very high gross margins
Sustained 85–90% gross margins indicate attractive unit economics and product-level profitability potential. Over the medium term this margin cushion supports reinvestment in R&D or commercial buildout and offers resilience to input-cost shocks, aiding long-term margin recovery when revenue scales.
Read all positive factors

Medrx Co., Ltd. (4586) vs. iShares MSCI Japan ETF (EWJ)

Medrx Co., Ltd. Business Overview & Revenue Model

Company Description
MedRx Co., Ltd, a pharmaceutical formulation development company, provides pharmaceutical drugs based on the transdermal absorption system in Japan. The company develops medicines based on Ionic liquid transdermal system (ILTS) and Nano-sized Coll...
How the Company Makes Money
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Medrx Co., Ltd. Financial Statement Overview

Summary
Strong 2025 revenue rebound and very high gross margins are outweighed by persistent, deep operating/net losses and consistently negative operating and free cash flow. Zero debt reduces solvency risk, but ongoing cash burn and negative ROE remain the core financial concern.
Income Statement
24
Negative
Balance Sheet
63
Positive
Cash Flow
18
Very Negative
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue45.24M128.08M257.92M29.53M59.48M8.35M
Gross Profit17.19M113.01M219.19M-18.43M10.45M-54.25M
EBITDA-1.24B-928.13M-754.62M-888.00M-1.05B-1.00B
Net Income-1.38B-937.37M-806.76M-932.90M-1.11B-1.06B
Balance Sheet
Total Assets1.93B2.16B2.27B2.05B1.40B2.11B
Cash, Cash Equivalents and Short-Term Investments1.67B1.75B1.98B1.72B994.02M1.70B
Total Debt0.000.000.000.000.000.00
Total Liabilities62.52M108.54M107.00M127.52M185.56M153.10M
Stockholders Equity1.87B2.05B2.17B1.92B1.21B1.96B
Cash Flow
Free Cash Flow0.00-970.86M-803.00M-913.76M-1.08B-926.23M
Operating Cash Flow0.00-888.11M-803.00M-913.00M-1.07B-923.69M
Investing Cash Flow0.00-82.75M-3.15M-759.00K-1.96M-2.54M
Financing Cash Flow0.00745.09M1.07B1.64B356.31M815.91M

Medrx Co., Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price113.00
Price Trends
50DMA
102.26
Negative
100DMA
109.16
Negative
200DMA
108.08
Negative
Market Momentum
MACD
-6.21
Positive
RSI
41.32
Neutral
STOCH
55.19
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For JP:4586, the sentiment is Negative. The current price of 113 is above the 20-day moving average (MA) of 95.15, above the 50-day MA of 102.26, and above the 200-day MA of 108.08, indicating a bearish trend. The MACD of -6.21 indicates Positive momentum. The RSI at 41.32 is Neutral, neither overbought nor oversold. The STOCH value of 55.19 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for JP:4586.

Medrx Co., Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
¥6.07B11.643.21%1.67%
55
Neutral
¥8.74B-13.67-90.96%36.19%60.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
¥6.84B-12.20324.27%18.93%
47
Neutral
¥6.34B-3.559.50%
43
Neutral
¥6.98B-0.93-46.69%-12.40%
42
Neutral
¥4.75B-10.38-50.34%-2.74%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
JP:4586
Medrx Co., Ltd.
80.00
17.00
26.98%
JP:4597
Solasia Pharma KK
32.00
0.00
0.00%
JP:4539
Nippon Chemiphar Co., Ltd.
1,681.00
244.85
17.05%
JP:4582
Symbio Pharmaceuticals Limited
90.00
-67.00
-42.68%
JP:4883
Modalis Therapeutics Corporation
66.00
-9.00
-12.00%
JP:4892
Cyfuse Biomedical K.K.
678.00
-295.00
-30.32%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 03, 2026