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Iterum Therapeutics (ITRMF)
OTHER OTC:ITRMF
US Market

Iterum Therapeutics (ITRMF) AI Stock Analysis

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ITRMF

Iterum Therapeutics

(OTC:ITRMF)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
$0.31
▼(-8.53% Downside)
Action:UpgradedDate:12/30/25
The score is held down primarily by weak financial fundamentals (minimal revenue, persistent losses, cash burn, and negative equity) and bearish technicals (price below major moving averages with negative MACD). The earnings call adds some support due to early launch traction and 2026 revenue guidance, but this is tempered by the need for additional capital, while the Nasdaq listing compliance issue adds further downside risk.
Positive Factors
Patent expansion (China & Mexico)
Extended patents in China and Mexico through 2039–2041 materially lengthen market exclusivity in key international jurisdictions. This strengthens long-term commercial upside, supports pricing power versus generics, and enhances licensing or partnering optionality across global markets.
Negative Factors
Negative shareholders' equity and elevated leverage
Negative equity and debt that exceeds assets constrain financial flexibility and increase refinancing and dilution risk. This capital-structure weakness can limit investment in commercial scale-up or R&D and raises vulnerability to adverse funding conditions over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Patent expansion (China & Mexico)
Extended patents in China and Mexico through 2039–2041 materially lengthen market exclusivity in key international jurisdictions. This strengthens long-term commercial upside, supports pricing power versus generics, and enhances licensing or partnering optionality across global markets.
Read all positive factors

Iterum Therapeutics (ITRMF) vs. SPDR S&P 500 ETF (SPY)

Iterum Therapeutics Business Overview & Revenue Model

Company Description
Iterum Therapeutics plc, a pharmaceutical company, develops and commercializes treatments for drug resistant bacterial infections in Ireland, Bermuda, and the United States. The company offers ORLYNVAH, an oral penem antibiotic for the treatment o...
How the Company Makes Money
Iterum Therapeutics makes money through the development and potential commercialization of its primary product candidate, sulopenem. The company's revenue model is expected to include income from the sale of sulopenem upon receiving regulatory app...

Iterum Therapeutics Financial Statement Overview

Summary
Very limited TTM revenue ($0.39M) with continued large losses (net loss ~$27.0M) and ongoing cash burn (operating/free cash flow about -$19.9M TTM). While losses, cash burn, and debt have improved versus prior years, negative shareholders’ equity (about -$7.4M TTM) and debt exceeding assets keep financial risk high.
Income Statement
12
Very Negative
Balance Sheet
18
Very Negative
Cash Flow
22
Negative
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue390.00K0.000.000.000.000.00
Gross Profit-668.00K-254.00K-1.75M-1.80M-2.10M-161.00K
EBITDA-23.07M-21.73M-34.58M-39.97M-83.20M-36.01M
Net Income-26.96M-24.77M-38.37M-44.43M-91.56M-52.01M
Balance Sheet
Total Assets32.50M44.59M26.26M66.83M91.51M32.79M
Cash, Cash Equivalents and Short-Term Investments11.00M24.13M23.93M60.80M81.34M14.57M
Total Debt33.73M45.53M18.96M30.10M30.43M48.08M
Total Liabilities39.88M48.68M32.66M38.83M41.27M83.35M
Stockholders Equity-7.38M-4.08M-6.40M28.00M50.23M-50.56M
Cash Flow
Free Cash Flow-19.93M-26.77M-39.34M-18.54M-15.90M-54.54M
Operating Cash Flow-19.91M-26.77M-39.33M-18.47M-15.84M-54.53M
Investing Cash Flow1.09M18.21M23.34M13.96M-54.59M-11.00K
Financing Cash Flow16.27M26.69M1.03M-1.82M83.13M64.47M

Iterum Therapeutics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.34
Price Trends
50DMA
0.20
Negative
100DMA
0.29
Negative
200DMA
0.53
Negative
Market Momentum
MACD
-0.05
Positive
RSI
26.53
Positive
STOCH
3.48
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ITRMF, the sentiment is Negative. The current price of 0.34 is above the 20-day moving average (MA) of 0.12, above the 50-day MA of 0.20, and below the 200-day MA of 0.53, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 26.53 is Positive, neither overbought nor oversold. The STOCH value of 3.48 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ITRMF.

Iterum Therapeutics Risk Analysis

Iterum Therapeutics disclosed 88 risk factors in its most recent earnings report. Iterum Therapeutics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Iterum Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$75.38M-2.21240.83%-49.17%23.37%
49
Neutral
$49.15M-311.80%588.40%61.76%
47
Neutral
$237.79M-2.32-162.49%5.51%
46
Neutral
$52.37M-1.28-105.17%
43
Neutral
$591.75K-0.8562.61%
43
Neutral
$37.13M-1.93-226.10%48.68%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ITRMF
Iterum Therapeutics
0.01
-1.11
-99.02%
CVM
Cel-Sci
4.39
-1.52
-25.72%
CLNN
Clene
6.40
3.40
113.33%
XLO
Xilio Therapeutics
8.69
-0.83
-8.72%
CAMP
CAMP4 Therapeutics Corporation
4.58
2.44
114.02%
RADX
Radiopharm Theranostics Limited Sponsored ADR
4.48
0.48
12.00%

Iterum Therapeutics Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
Iterum Therapeutics Faces Nasdaq Listing Compliance Challenge
Negative
Dec 12, 2025
On December 11, 2025, Iterum Therapeutics received a notification from Nasdaq indicating that it no longer meets the listing requirements due to its market value of listed securities falling below $35 million for 30 consecutive business days. The ...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 30, 2025