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Acurx Pharmaceuticals (ACXP)
NASDAQ:ACXP

Acurx Pharmaceuticals (ACXP) AI Stock Analysis

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ACXP

Acurx Pharmaceuticals

(NASDAQ:ACXP)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
$3.00
▲(7.91% Upside)
Action:ReiteratedDate:03/28/26
The score is held down primarily by weak financial performance (no revenue, persistent losses, and worsening cash burn), which elevates financing risk. Technical indicators are neutral-to-modestly constructive versus recent months but still below long-term trend. Valuation is constrained by losses and no dividend, while earnings/corporate updates provide some offset through compliance progress, improved cash, IP advancement, and a broadened clinical strategy.
Positive Factors
Intellectual Property Portfolio
Acurx's expanding patent estate across multiple jurisdictions creates a durable barrier to entry for competitors, supports exclusive commercial rights for ACX-375C/ibezapolstat, and enhances bargaining power for licensing or partnerships, improving long-term commercialization prospects.
Negative Factors
Worsening Cash Burn
Persistent negative operating and free cash flows and a marked 2025 deterioration increase the company's reliance on external financing. For a pre-revenue biotech, this elevates dilution and execution risk, potentially forcing delays in trials or unfavorable funding terms over the medium term.
Read all positive and negative factors
Positive Factors
Negative Factors
Intellectual Property Portfolio
Acurx's expanding patent estate across multiple jurisdictions creates a durable barrier to entry for competitors, supports exclusive commercial rights for ACX-375C/ibezapolstat, and enhances bargaining power for licensing or partnerships, improving long-term commercialization prospects.
Read all positive factors

Acurx Pharmaceuticals (ACXP) vs. SPDR S&P 500 ETF (SPY)

Acurx Pharmaceuticals Business Overview & Revenue Model

Company Description
Acurx Pharmaceuticals, Inc., a clinical stage biopharmaceutical company, develops antibiotics to treat bacterial infections. Its lead antibiotic candidate is ibezapolstat, a novel mechanism of action that targets the polymerase IIIC enzyme that ha...
How the Company Makes Money
As a clinical-stage company, Acurx does not have established, recurring product revenue from marketed drugs. Its cash inflows have historically been driven primarily by financing activities (e.g., issuing equity) rather than operating revenue; spe...

Acurx Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 12, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Neutral
The earnings call presented a mix of positive developments, such as achieving NASDAQ compliance, patent expansion, and successful presentations, alongside ongoing financial challenges and significant reductions in R&D expenses. The company's improved financial position and strategic scientific advancements were notable, though the net loss and reduced R&D spending highlight areas of concern.
Positive Updates
NASDAQ Compliance Achieved
Acurx Pharmaceuticals effected a 1-for-20 reverse stock split, regaining compliance with NASDAQ listing rules with a minimum bid price of $1 per share and a stockholder equity threshold of $2.5 million.
Negative Updates
Decrease in R&D Expenses
Research and development expenses decreased significantly, from $1.2 million in Q3 2024 to $0.4 million in Q3 2025, primarily due to reductions in manufacturing and consulting costs.
Read all updates
Q3-2025 Updates
Negative
NASDAQ Compliance Achieved
Acurx Pharmaceuticals effected a 1-for-20 reverse stock split, regaining compliance with NASDAQ listing rules with a minimum bid price of $1 per share and a stockholder equity threshold of $2.5 million.
Read all positive updates
Company Guidance
During the third quarter of 2025, Acurx Pharmaceuticals provided several key updates regarding its financial performance and strategic activities. The company effected a 1-for-20 reverse stock split and regained compliance with NASDAQ's minimum bid price and stockholder equity requirements. Financially, Acurx ended the quarter with $5.9 million in cash, up from $3.7 million at the end of 2024, and raised an additional $1.7 million through an equity line of credit. Research and development expenses decreased to $0.4 million from $1.2 million in the same quarter the previous year, while general and administrative expenses remained flat at $1.6 million. The company reported a net loss of $2 million, or $1.23 per diluted share, compared to a $2.8 million loss, or $3.45 per share, in the prior year. Additionally, Acurx highlighted progress in its ibezapolstat program, including new patent grants, scientific publications, and presentations at industry conferences, while continuing to seek funding opportunities for a phase three clinical trial.

Acurx Pharmaceuticals Financial Statement Overview

Summary
Pre-revenue profile with persistent losses and consistently negative operating/free cash flow. Cash burn worsened in 2025, raising financing/dilution risk, partially offset by low leverage and limited debt.
Income Statement
12
Very Negative
Balance Sheet
38
Negative
Cash Flow
18
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit0.000.000.000.000.00
EBITDA-8.09M0.00-14.58M-12.09M-12.81M
Net Income-7.97M-14.10M-14.58M-12.09M-12.75M
Balance Sheet
Total Assets7.69M3.86M7.71M9.38M13.25M
Cash, Cash Equivalents and Short-Term Investments7.56B3.71M7.47M9.11M12.96M
Total Debt0.000.000.000.000.00
Total Liabilities2.42M3.24M3.04M2.06M843.91K
Stockholders Equity5.27M615.12K4.67M7.32M12.41M
Cash Flow
Free Cash Flow-6.79B-10.38M-9.80M-7.54M-5.01M
Operating Cash Flow-6.79B-10.38M-9.80M-7.54M-5.01M
Investing Cash Flow0.000.000.000.000.00
Financing Cash Flow10.64B6.62M8.16M3.70M14.80M

Acurx Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price2.78
Price Trends
50DMA
2.92
Positive
100DMA
3.18
Negative
200DMA
4.74
Negative
Market Momentum
MACD
0.07
Positive
RSI
43.92
Neutral
STOCH
7.43
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For ACXP, the sentiment is Negative. The current price of 2.78 is below the 20-day moving average (MA) of 4.36, below the 50-day MA of 2.92, and below the 200-day MA of 4.74, indicating a neutral trend. The MACD of 0.07 indicates Positive momentum. The RSI at 43.92 is Neutral, neither overbought nor oversold. The STOCH value of 7.43 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for ACXP.

Acurx Pharmaceuticals Risk Analysis

Acurx Pharmaceuticals disclosed 54 risk factors in its most recent earnings report. Acurx Pharmaceuticals reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Acurx Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$8.45M-0.47-291.07%61.10%
47
Neutral
$8.84M-0.31-97.58%-46.88%34.83%
46
Neutral
$77.38M-5.32-71.26%185.71%79.03%
44
Neutral
$6.54M-0.82-420.31%1.70%-111.67%
39
Underperform
$394.39K-1302.82%99.09%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
ACXP
Acurx Pharmaceuticals
2.96
-3.75
-55.89%
IBIO
Ibio
2.24
1.03
85.12%
WINT
Windtree Therapeutics
0.01
-1.30
-99.16%
BRTX
BioRestorative Therapies
0.26
-1.48
-85.24%
LIXT
Lixte Biotechnology Holdings
2.85
1.72
152.21%
BOLT
Bolt Biotherapeutics
4.60
-1.82
-28.35%

Acurx Pharmaceuticals Corporate Events

Business Operations and StrategyExecutive/Board ChangesProduct-Related Announcements
Acurx Advances Ibezapolstat Program for Recurrent C. difficile
Positive
Mar 9, 2026
On March 9, 2026, Acurx Pharmaceuticals’ compensation committee approved voluntary 10% base-salary cuts for its top executives and a 10% reduction in cash retainers for non-employee directors, effective April 1, 2026, while leaving bonus tar...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 28, 2026