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Hyperion DeFi (HYPD)
NASDAQ:HYPD
US Market
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Hyperion DeFi (HYPD) AI Stock Analysis

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HYPD

Hyperion DeFi

(NASDAQ:HYPD)

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Neutral 45 (OpenAI - 4o)
Rating:45Neutral
Price Target:
$3.50
▼(-5.41% Downside)
The overall stock score is primarily impacted by the company's weak financial performance and poor valuation metrics. Despite positive sentiment from the earnings call indicating strategic transformation and growth, the financial instability and bearish technical indicators weigh heavily on the score.
Positive Factors
Revenue Growth
Significant revenue growth from digital assets indicates strong market demand and effective monetization strategies, supporting long-term business expansion.
Strategic Transformation
The strategic shift to a digital asset treasury company enhances Hyperion DeFi's market positioning and aligns with industry trends, fostering sustainable growth.
Innovative Revenue Services
The introduction of innovative services like the HYPE Asset Use Service demonstrates Hyperion DeFi's ability to diversify revenue streams and capitalize on new market opportunities.
Negative Factors
Regulatory Uncertainty
Regulatory uncertainty in the DeFi space poses risks to operational stability and strategic planning, potentially impacting long-term growth and compliance costs.
Nonrecurring Gains
Nonrecurring gains from liability reductions may inflate short-term financial performance, but do not contribute to sustainable profitability or cash flow.
Legacy Business Challenges
Ongoing challenges with legacy business development may divert resources and focus from core DeFi operations, affecting overall business efficiency and growth.

Hyperion DeFi (HYPD) vs. SPDR S&P 500 ETF (SPY)

Hyperion DeFi Business Overview & Revenue Model

Company DescriptionA U.S.-based firm pivoting from ophthalmic drug-delivery tech (Optejet) to becoming the first Nasdaq-listed U.S. company with a cryptocurrency treasury denominated in HYPE tokens from the Hyperliquid blockchain; also operates a validator (“Kinetiq × Hyperion”) and continues DeFi staking strategies alongside ongoing development of Optejet UFD™ for eye care.
How the Company Makes MoneyHyperion DeFi generates revenue primarily through transaction fees collected from users engaging in trading activities on its decentralized exchange and participating in liquidity pools. Additionally, the platform earns income from yield farming protocols by charging fees on the returns generated for users. Another key revenue stream involves partnerships with other blockchain projects and DeFi platforms, where Hyperion DeFi may receive a share of fees or commissions for facilitating transactions or providing liquidity. Moreover, any governance tokens issued by the platform could also provide a revenue model through staking rewards or secondary market sales.

Hyperion DeFi Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Positive
The earnings call reflects a positive transformation and growth trajectory for Hyperion DeFi, marked by record financial metrics, successful strategic initiatives, and promising guidance. However, challenges related to regulatory uncertainty and reliance on nonrecurring gains were noted.
Q3-2025 Updates
Positive Updates
Record Income from Operations
Achieved income from operations of $4.4 million and GAAP net income of $6.6 million, both record highs for the company.
Successful Strategic Transformation
Successfully executed a significant corporate transformation from a biotech company to a digital asset treasury company focused on the Hyperliquid ecosystem.
Strong Revenue Generation from Digital Assets
Generated $303,000 of revenue in Q3 2025 from digital assets, significantly higher than the less than $2,000 realized in Q3 2024.
Growth in Validator Participation
Validator received 60% month-over-month growth in tokens delegated from September to October, reaching 13.2 million tokens.
Positive Financial Guidance
Initiated financial guidance with expectations for Q4 2025 adjusted revenues between $475,000 and $515,000, representing a 31% to 43% quarter-over-quarter increase.
Innovative Revenue Services
Launched first HYPE Asset Use Service agreement with Credo Payment, demonstrating unique revenue opportunities beyond simple token appreciation.
Negative Updates
Regulatory Uncertainty
Operating in an extremely dynamic regulatory environment, although broadly favorable, presents challenges regarding clarity around crypto and DeFi interactions with existing financial infrastructure.
Nonrecurring Gains
Q3 2025 results were boosted by $2.4 million due to reductions in life sciences liabilities, which are not expected to be recurring.
Legacy Business Challenges
Continuing the development of the Optejet User Filled Device, with commercialization potential but still completing R&D and testing to reach a position of commercial viability.
Company Guidance
During the call, Hyperion DeFi provided comprehensive guidance and metrics highlighting its strategic transformation and financial performance for the third quarter of 2025. The company reported a record GAAP net income of $6.6 million and an adjusted EBITDA of $8.0 million. Hyperliquid, the blockchain ecosystem Hyperion focuses on, generates approximately $1.3 billion in annualized revenue based on a $3.5 million daily run rate, making it the #1 revenue-generating blockchain excluding stablecoins. The Hyperliquid ecosystem has amassed over 800,000 users and facilitates up to 100,000 transactions per second. Hyperion DeFi holds 1.7 million HYPE tokens, valued at approximately $77.8 million, including liquid staking tokens, contributing to its strategic treasury. The company anticipates Q4 2025 adjusted revenues between $475,000 and $515,000, aiming for operating cash flow positivity in 2026. Hyperion DeFi’s strategy leverages its digital asset treasury for revenue generation through staking, validator commissions, yield enhancement, and DeFi monetization, with a focus on expanding institutional-grade infrastructure.

Hyperion DeFi Financial Statement Overview

Summary
Eyenovia is facing significant financial challenges with high operational losses, negative profitability margins, and a precarious balance sheet. While revenue growth is a positive sign, the company's overall financial health is at risk due to negative equity and insufficient cash flow generation.
Income Statement
35
Negative
Eyenovia has shown considerable revenue growth from 2023 to 2024 but continues to face significant losses. The gross profit margin remains negative, and the net profit margin is significantly low due to high operational costs and expenses. EBIT and EBITDA margins are also deeply negative, indicating operational inefficiencies.
Balance Sheet
25
Negative
The company's financial leverage is concerning, with a negative stockholders' equity indicating potential financial instability. The debt-to-equity ratio cannot be calculated due to negative equity, and the equity ratio is also negative, highlighting a risky financial structure.
Cash Flow
30
Negative
Eyenovia's cash flow remains negative, with decreasing free cash flow over the years. The operating cash flow to net income ratio is negative, suggesting inefficiencies in converting revenue into cash. Free cash flow to net income is also negative, indicating financial strain.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue345.32K57.34K3.79K0.0014.00M2.00M
Gross Profit-3.13M-3.87M-12.22K0.0012.40M1.20M
EBITDA-23.27M-46.21M-24.11M-26.32M-12.17M-19.69M
Net Income-25.50M-49.82M-27.26M-28.01M-12.78M-19.77M
Balance Sheet
Total Assets82.79M3.67M28.78M31.04M31.66M33.91M
Cash, Cash Equivalents and Short-Term Investments8.22M2.12M14.85M22.86M19.46M28.37M
Total Debt8.49M11.24M16.08M10.12M7.15M463.35K
Total Liabilities12.03M16.76M19.78M13.80M11.19M18.60M
Stockholders Equity70.76M-13.10M9.00M17.23M20.47M15.30M
Cash Flow
Free Cash Flow-62.32M-30.28M-27.81M-25.98M-22.49M-6.65M
Operating Cash Flow-16.82M-30.12M-23.84M-25.11M-20.87M-6.38M
Investing Cash Flow-65.64M-161.48K-3.97M-874.75K-1.62M-261.26K
Financing Cash Flow83.49M17.55M19.79M21.51M21.46M20.86M

Hyperion DeFi Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.70
Price Trends
50DMA
7.15
Negative
100DMA
7.97
Negative
200DMA
5.43
Negative
Market Momentum
MACD
-0.89
Negative
RSI
33.96
Neutral
STOCH
29.18
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HYPD, the sentiment is Negative. The current price of 3.7 is below the 20-day moving average (MA) of 4.95, below the 50-day MA of 7.15, and below the 200-day MA of 5.43, indicating a bearish trend. The MACD of -0.89 indicates Negative momentum. The RSI at 33.96 is Neutral, neither overbought nor oversold. The STOCH value of 29.18 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HYPD.

Hyperion DeFi Risk Analysis

Hyperion DeFi disclosed 65 risk factors in its most recent earnings report. Hyperion DeFi reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Hyperion DeFi Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
$68.82M-5.71%-13.79%-132.21%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$37.68M-0.18-68.49%984.82%63.54%
45
Neutral
$49.12M-2.80-157.91%-18.96%8.98%
42
Neutral
$47.10M-96.15%-8.97%47.29%
38
Underperform
$51.11M-1.1512.24%47.45%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HYPD
Hyperion DeFi
3.70
-3.65
-49.66%
CTSO
Cytosorbents
0.75
-0.20
-21.05%
SRTS
Sensus Healthcare
4.00
-4.58
-53.38%
TELA
TELA Bio
1.13
-1.81
-61.56%
ICCM
Icecure Medical
0.72
-0.07
-8.86%
BDMD
Baird Medical Investment Holdings
1.47
-0.83
-36.09%

Hyperion DeFi Corporate Events

Business Operations and StrategyPrivate Placements and Financing
Hyperion DeFi Enters $500M Sales Agreement
Positive
Nov 17, 2025

On November 14, 2025, Hyperion DeFi, Inc. entered into a Sales Agreement with Cantor Fitzgerald & Co. and Chardan Capital Markets, LLC, allowing the company to offer and sell shares of its common stock through these sales agents. The agreement permits the company to sell shares with an aggregate offering price of up to $500 million, with sales executed in various transaction types, including block trades and at-the-market offerings. The sales agents will earn a 4% commission on the gross sales proceeds, and the offering will terminate upon the sale of all shares or termination of the agreement. This move is expected to impact Hyperion DeFi’s market positioning by potentially increasing its capital for further expansion and operations.

The most recent analyst rating on (HYPD) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Hyperion DeFi’s Earnings Call Highlights Growth and Challenges
Nov 16, 2025

The recent earnings call for Hyperion DeFi showcased a positive transformation and growth trajectory, highlighted by record financial metrics and successful strategic initiatives. The company expressed optimism with promising guidance, although it acknowledged challenges related to regulatory uncertainty and reliance on nonrecurring gains.

Hyperion DeFi Achieves Record Q3 2025 Earnings
Nov 14, 2025

Hyperion DeFi, Inc., a publicly listed company in the U.S., is pioneering the development of a strategic treasury of Hyperliquid’s native token, HYPE, providing investors with streamlined access to the Hyperliquid ecosystem, a rapidly growing blockchain platform.

Business Operations and StrategyFinancial Disclosures
Hyperion DeFi Reports Record Q3 2025 Net Income
Positive
Nov 13, 2025

On November 13, 2025, Hyperion DeFi announced its third-quarter financial results for the period ending September 30, 2025, reporting a record net income of $6.6 million. The company has undergone a significant transformation, pivoting from ophthalmic technology to becoming a leading institutional gateway for DeFi innovation. The company’s new digital asset treasury strategy has led to substantial financial growth, with revenue increasing from $1,625 in Q3 2024 to $302,506 in Q3 2025. Hyperion DeFi has also launched a co-brand validator, ‘Kinetiq x Hyperion,’ and has seen a 60% month-over-month increase in staked HYPE tokens. The company anticipates continued growth with positive operating cash flows expected in 2026.

The most recent analyst rating on (HYPD) stock is a Sell with a $5.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Hyperion DeFi Enters Joint Validator Agreement
Positive
Oct 31, 2025

On October 27, 2025, Hyperion DeFi entered a Joint Validator Agreement with Kinetiq Research and Pier Two to operate a co-branded validator node on the Hyperliquid blockchain, effective retroactively from June 25, 2025. This agreement involves shared responsibilities and revenue-sharing arrangements, enhancing Hyperion’s operational capacity and market positioning in blockchain validation. Additionally, Hyperion announced a strategic partnership with Felix to launch a perpetual futures market on the Hyperliquid protocol, leveraging 500,000 HYPE tokens. This partnership aims to expand Hyperliquid’s product suite and revenue streams, marking a significant step in decentralized finance innovation.

The most recent analyst rating on (HYPD) stock is a Hold with a $7.00 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Hyperion DeFi Board Member Michael Rowe Resigns
Negative
Oct 2, 2025

On September 30, 2025, Michael Rowe resigned from the Board of Directors of Hyperion DeFi, Inc. This departure may impact the company’s governance and strategic direction.

The most recent analyst rating on (HYPD) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyExecutive/Board Changes
Hyperion DeFi Appoints David Knox as CFO
Positive
Sep 29, 2025

On September 29, 2025, Hyperion DeFi announced the appointment of David Knox as Chief Financial Officer, marking a strategic move to enhance governance and accelerate its decentralized finance strategy. Knox, who previously held significant roles at PayPal and SoFi, brings extensive expertise in capital markets and financial services, and aims to position Hyperion DeFi as a bridge between traditional finance and the decentralized future, driving value for the ecosystem and shareholders.

The most recent analyst rating on (HYPD) stock is a Hold with a $9.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Hyperion DeFi Expands ATM Offering to $100 Million
Positive
Sep 25, 2025

On September 24, 2025, Hyperion DeFi, Inc. amended its sales agreement with Chardan Capital Markets, increasing its at-the-market offering program from $50 million to $100 million. As of this date, the company has sold over 4 million shares, generating approximately $29 million in net proceeds, enhancing its liquidity and market presence.

The most recent analyst rating on (HYPD) stock is a Hold with a $8.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Executive/Board ChangesDelistings and Listing ChangesRegulatory Filings and Compliance
Hyperion DeFi Announces New Interim CEO and Board Expansion
Positive
Sep 8, 2025

On September 2, 2025, Hyperion DeFi, Inc. announced it had regained compliance with Nasdaq’s minimum equity requirement, following a previous notice of non-compliance. Additionally, the company experienced significant leadership changes, with CEO Michael Rowe resigning and Hyunsu Jung stepping in as Interim CEO. The board also expanded to include Happy Walters, a seasoned executive with expertise in sectors like telehealth and blockchain, who will serve on the Nominating and Governance Committee.

The most recent analyst rating on (HYPD) stock is a Hold with a $6.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyShareholder Meetings
Hyperion DeFi Expands Capital Structure Post-Annual Meeting
Neutral
Aug 21, 2025

The 2025 Annual Meeting of Stockholders for Hyperion DeFi took place virtually on August 18, 2025, with a quorum of 51.40% of eligible shares present. Key decisions included the election of directors, ratification of CBIZ CPAs P.C. as the accounting firm, and approval of various amendments to the company’s charter and stock incentive plan. Notably, a proposal to allow stockholders to act by written consent did not pass, and an amendment to increase authorized shares was approved, indicating strategic moves to expand the company’s capital structure.

The most recent analyst rating on (HYPD) stock is a Hold with a $6.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 02, 2025