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Hyperion DeFi (HYPD)
NASDAQ:HYPD
US Market

Hyperion DeFi (HYPD) AI Stock Analysis

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HYPD

Hyperion DeFi

(NASDAQ:HYPD)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$4.00
▲(13.64% Upside)
The score is held down primarily by weak financial performance (negative gross profit, very large losses, and significant cash burn), with only partial offset from a positive earnings-call trajectory and guidance. Technicals are mixed (short-term strength but longer-term downtrend), and valuation signals are limited due to a negative P/E and no dividend support.
Positive Factors
Revenue from digital-assets
Material growth in digital-asset revenue demonstrates early product-market fit for Hyperion’s DeFi services. Sustained transactional, staking and validator fees can build recurring revenue streams and improve operating leverage as user adoption and on-chain activity scale, supporting medium-term profitability.
Manageable leverage on balance sheet
Low relative debt reduces refinancing and interest risks while the equity buffer provides flexibility to fund operations or strategic investments. This capital structure gives management scope to pursue the digital-treasury strategy and absorb token-value volatility without immediate solvency pressure.
Consolidated leadership and strategic pivot
Formalizing a seasoned leadership team after the pivot to a digital-asset treasury improves governance, capital-markets credibility and execution capability. Strong management continuity increases the odds of executing partnerships, validator growth and institutional product rollouts over the coming quarters.
Negative Factors
Negative gross profit and poor unit economics
Negative gross profit indicates products and services are delivered at a loss, signalling structurally unsustainable unit economics. Unless pricing, cost base or product mix change materially, scale alone won’t restore profitability, posing a multi-quarter risk to durable margin recovery.
Large recurring cash burn
Persistent operating cash outflows create an ongoing financing need that can force equity raises, token monetization or asset sales. This structural cash-burn trajectory constrains investment optionality, increases dilution risk, and pressures execution unless operating cash flow turns positive as guided.
Treasury/token concentration and regulatory risk
Heavy reliance on HYPE token holdings and treasury monetization ties balance-sheet strength and recurring revenue to market prices and regulatory clarity. Structural regulatory shifts or token devaluation could materially reduce capital and recurring income, undermining the firm’s strategic financing model.

Hyperion DeFi (HYPD) vs. SPDR S&P 500 ETF (SPY)

Hyperion DeFi Business Overview & Revenue Model

Company DescriptionA U.S.-based firm pivoting from ophthalmic drug-delivery tech (Optejet) to becoming the first Nasdaq-listed U.S. company with a cryptocurrency treasury denominated in HYPE tokens from the Hyperliquid blockchain; also operates a validator (“Kinetiq × Hyperion”) and continues DeFi staking strategies alongside ongoing development of Optejet UFD™ for eye care.
How the Company Makes MoneyHyperion DeFi generates revenue primarily through transaction fees collected from users engaging in trading activities on its decentralized exchange and participating in liquidity pools. Additionally, the platform earns income from yield farming protocols by charging fees on the returns generated for users. Another key revenue stream involves partnerships with other blockchain projects and DeFi platforms, where Hyperion DeFi may receive a share of fees or commissions for facilitating transactions or providing liquidity. Moreover, any governance tokens issued by the platform could also provide a revenue model through staking rewards or secondary market sales.

Hyperion DeFi Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:May 07, 2026
Earnings Call Sentiment Positive
The earnings call reflects a positive transformation and growth trajectory for Hyperion DeFi, marked by record financial metrics, successful strategic initiatives, and promising guidance. However, challenges related to regulatory uncertainty and reliance on nonrecurring gains were noted.
Q3-2025 Updates
Positive Updates
Record Income from Operations
Achieved income from operations of $4.4 million and GAAP net income of $6.6 million, both record highs for the company.
Successful Strategic Transformation
Successfully executed a significant corporate transformation from a biotech company to a digital asset treasury company focused on the Hyperliquid ecosystem.
Strong Revenue Generation from Digital Assets
Generated $303,000 of revenue in Q3 2025 from digital assets, significantly higher than the less than $2,000 realized in Q3 2024.
Growth in Validator Participation
Validator received 60% month-over-month growth in tokens delegated from September to October, reaching 13.2 million tokens.
Positive Financial Guidance
Initiated financial guidance with expectations for Q4 2025 adjusted revenues between $475,000 and $515,000, representing a 31% to 43% quarter-over-quarter increase.
Innovative Revenue Services
Launched first HYPE Asset Use Service agreement with Credo Payment, demonstrating unique revenue opportunities beyond simple token appreciation.
Negative Updates
Regulatory Uncertainty
Operating in an extremely dynamic regulatory environment, although broadly favorable, presents challenges regarding clarity around crypto and DeFi interactions with existing financial infrastructure.
Nonrecurring Gains
Q3 2025 results were boosted by $2.4 million due to reductions in life sciences liabilities, which are not expected to be recurring.
Legacy Business Challenges
Continuing the development of the Optejet User Filled Device, with commercialization potential but still completing R&D and testing to reach a position of commercial viability.
Company Guidance
During the call, Hyperion DeFi provided comprehensive guidance and metrics highlighting its strategic transformation and financial performance for the third quarter of 2025. The company reported a record GAAP net income of $6.6 million and an adjusted EBITDA of $8.0 million. Hyperliquid, the blockchain ecosystem Hyperion focuses on, generates approximately $1.3 billion in annualized revenue based on a $3.5 million daily run rate, making it the #1 revenue-generating blockchain excluding stablecoins. The Hyperliquid ecosystem has amassed over 800,000 users and facilitates up to 100,000 transactions per second. Hyperion DeFi holds 1.7 million HYPE tokens, valued at approximately $77.8 million, including liquid staking tokens, contributing to its strategic treasury. The company anticipates Q4 2025 adjusted revenues between $475,000 and $515,000, aiming for operating cash flow positivity in 2026. Hyperion DeFi’s strategy leverages its digital asset treasury for revenue generation through staking, validator commissions, yield enhancement, and DeFi monetization, with a focus on expanding institutional-grade infrastructure.

Hyperion DeFi Financial Statement Overview

Summary
Despite sharp TTM revenue acceleration, fundamentals remain weak: negative gross profit, extremely large operating losses versus revenue, and heavy free-cash-flow burn (about -$62M) implying ongoing funding risk. The latest balance sheet shows moderate leverage (debt-to-equity ~0.23), but prior-period volatility (including negative equity in 2024) limits confidence.
Income Statement
12
Very Negative
Revenue accelerated sharply in TTM (Trailing-Twelve-Months) (up 677% versus the prior period) and improved from very low levels in 2023–2024, but the business remains deeply unprofitable. Gross profit is negative in 2024 and TTM (Trailing-Twelve-Months), indicating products/services are being delivered at a loss, and operating losses are extremely large relative to revenue (net margin around -900% in TTM (Trailing-Twelve-Months)). The core issue is a cost structure that is far out of line with the current revenue base.
Balance Sheet
45
Neutral
The TTM (Trailing-Twelve-Months) balance sheet shows sizable equity and moderate leverage (debt-to-equity ~0.23), which is a relative strength versus many loss-making peers. However, the balance sheet has been volatile: 2024 shows negative equity, and returns on equity are negative in most periods (reflecting persistent losses). Overall, leverage looks manageable on the latest view, but stability and capital structure consistency are key risks.
Cash Flow
16
Very Negative
Cash generation is weak, with negative operating cash flow across all periods and a very large cash burn in TTM (Trailing-Twelve-Months) (free cash flow about -$62M). Free cash flow also deteriorated meaningfully versus 2024, and cash outflows remain substantial relative to reported losses, pointing to ongoing funding needs if this trajectory continues. The main positive is that cash flow and earnings are directionally consistent (both negative), but the magnitude of burn is the overriding concern.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue345.32K57.34K3.79K0.0014.00M2.00M
Gross Profit-2.83M-3.87M-12.22K0.0012.40M1.20M
EBITDA-23.27M-46.21M-24.11M-26.32M-12.17M-19.69M
Net Income-25.50M-49.82M-27.26M-28.01M-12.78M-19.77M
Balance Sheet
Total Assets82.79M3.67M28.78M31.04M31.66M33.91M
Cash, Cash Equivalents and Short-Term Investments8.22M2.12M14.85M22.86M19.46M28.37M
Total Debt8.49M11.24M16.08M10.12M7.15M463.35K
Total Liabilities12.03M16.76M19.78M13.80M11.19M18.60M
Stockholders Equity70.76M-13.10M9.00M17.23M20.47M15.30M
Cash Flow
Free Cash Flow-62.32M-30.28M-27.81M-25.98M-22.49M-6.65M
Operating Cash Flow-16.82M-30.12M-23.84M-25.11M-20.87M-6.38M
Investing Cash Flow-65.64M-161.48K-3.97M-874.75K-1.62M-261.26K
Financing Cash Flow83.49M17.55M19.79M21.51M21.46M20.86M

Hyperion DeFi Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price3.52
Price Trends
50DMA
3.65
Negative
100DMA
6.07
Negative
200DMA
5.86
Negative
Market Momentum
MACD
-0.09
Negative
RSI
49.97
Neutral
STOCH
76.55
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HYPD, the sentiment is Neutral. The current price of 3.52 is above the 20-day moving average (MA) of 3.40, below the 50-day MA of 3.65, and below the 200-day MA of 5.86, indicating a neutral trend. The MACD of -0.09 indicates Negative momentum. The RSI at 49.97 is Neutral, neither overbought nor oversold. The STOCH value of 76.55 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for HYPD.

Hyperion DeFi Risk Analysis

Hyperion DeFi disclosed 65 risk factors in its most recent earnings report. Hyperion DeFi reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Hyperion DeFi Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
$84.26M-27.77-5.71%-13.79%-132.21%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$28.77M-0.16-68.49%984.82%63.54%
45
Neutral
$41.98M-2.39-157.91%-18.96%8.98%
44
Neutral
$39.57M-3.32-96.15%-8.97%47.29%
44
Neutral
$44.53M-1.1312.24%47.45%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HYPD
Hyperion DeFi
3.52
0.84
31.34%
CTSO
Cytosorbents
0.63
-0.37
-37.00%
SRTS
Sensus Healthcare
5.13
-2.98
-36.74%
TELA
TELA Bio
1.00
-1.67
-62.55%
ICCM
Icecure Medical
0.61
-0.63
-50.73%
BDMD
Baird Medical Investment Holdings
1.00
-5.74
-85.16%

Hyperion DeFi Corporate Events

Business Operations and StrategyExecutive/Board Changes
Hyperion DeFi Finalizes Leadership Team and Equity Conversion
Positive
Jan 5, 2026

On January 5, 2026, Hyperion DeFi converted 100,000 shares of its Series A Non-Voting Preferred Stock into 300,000 common shares, for no additional consideration, in an unregistered transaction relying on private offering exemptions, modestly shifting its capital structure toward common equity. Effective January 1, 2026, the board confirmed former interim CEO and current Chief Investment Officer Hyunsu Jung as permanent chief executive with a new employment agreement running through January 17, 2029, and on January 5, 2026, the company also announced the recent appointment of David Knox as chief financial officer and the upcoming arrival of veteran deal lawyer Robert Rubenstein as general counsel on January 12, 2026, collectively solidifying a leadership team aimed at strengthening governance, capital markets credibility and execution of its digital-asset-focused strategy.

The most recent analyst rating on (HYPD) stock is a Buy with a $7.75 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyRegulatory Filings and Compliance
Hyperion DeFi Highlights Risks in HYPE Token Strategy
Negative
Dec 10, 2025

Hyperion DeFi has updated its risk factors, highlighting the volatility and risks associated with its HYPE token and treasury strategy. The company acknowledges the potential for significant financial impact due to the fluctuating value of HYPE, regulatory uncertainties, and technological challenges. The release outlines various risks, including market volatility, regulatory scrutiny, and technological vulnerabilities, which could affect the company’s financial condition and stock value. The company also notes the competitive landscape and the potential for emerging technologies to impact the demand for HYPE.

The most recent analyst rating on (HYPD) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Hyperion DeFi Enters $500M Sales Agreement
Positive
Nov 17, 2025

On November 14, 2025, Hyperion DeFi, Inc. entered into a Sales Agreement with Cantor Fitzgerald & Co. and Chardan Capital Markets, LLC, allowing the company to offer and sell shares of its common stock through these sales agents. The agreement permits the company to sell shares with an aggregate offering price of up to $500 million, with sales executed in various transaction types, including block trades and at-the-market offerings. The sales agents will earn a 4% commission on the gross sales proceeds, and the offering will terminate upon the sale of all shares or termination of the agreement. This move is expected to impact Hyperion DeFi’s market positioning by potentially increasing its capital for further expansion and operations.

The most recent analyst rating on (HYPD) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyFinancial Disclosures
Hyperion DeFi Reports Record Q3 2025 Net Income
Positive
Nov 13, 2025

On November 13, 2025, Hyperion DeFi announced its third-quarter financial results for the period ending September 30, 2025, reporting a record net income of $6.6 million. The company has undergone a significant transformation, pivoting from ophthalmic technology to becoming a leading institutional gateway for DeFi innovation. The company’s new digital asset treasury strategy has led to substantial financial growth, with revenue increasing from $1,625 in Q3 2024 to $302,506 in Q3 2025. Hyperion DeFi has also launched a co-brand validator, ‘Kinetiq x Hyperion,’ and has seen a 60% month-over-month increase in staked HYPE tokens. The company anticipates continued growth with positive operating cash flows expected in 2026.

The most recent analyst rating on (HYPD) stock is a Sell with a $5.50 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Business Operations and StrategyProduct-Related Announcements
Hyperion DeFi Enters Joint Validator Agreement
Positive
Oct 31, 2025

On October 27, 2025, Hyperion DeFi entered a Joint Validator Agreement with Kinetiq Research and Pier Two to operate a co-branded validator node on the Hyperliquid blockchain, effective retroactively from June 25, 2025. This agreement involves shared responsibilities and revenue-sharing arrangements, enhancing Hyperion’s operational capacity and market positioning in blockchain validation. Additionally, Hyperion announced a strategic partnership with Felix to launch a perpetual futures market on the Hyperliquid protocol, leveraging 500,000 HYPE tokens. This partnership aims to expand Hyperliquid’s product suite and revenue streams, marking a significant step in decentralized finance innovation.

The most recent analyst rating on (HYPD) stock is a Hold with a $7.00 price target. To see the full list of analyst forecasts on Hyperion DeFi stock, see the HYPD Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 29, 2026