Cytosorbents Corp (CTSO)
NASDAQ:CTSO
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Cytosorbents (CTSO) AI Stock Analysis

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CTSO

Cytosorbents

(NASDAQ:CTSO)

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Underperform 38 (OpenAI - 4o)
Rating:38Underperform
Price Target:
$0.50
▼(-24.24% Downside)
Cytosorbents' stock score is primarily impacted by its challenging financial performance and bearish technical indicators. The company's high leverage and negative cash flows pose significant risks. Despite some positive developments in revenue growth and strategic initiatives, the overall outlook remains cautious due to ongoing profitability challenges and weak valuation metrics.
Positive Factors
Revenue Growth
The 10% revenue growth indicates strong demand for CytoSorbents' products, suggesting potential for continued market expansion and increased adoption.
Gross Margin Improvement
Improved gross margins reflect efficient cost management and pricing power, contributing to better profitability potential over the long term.
Strategic Cost Reductions
The strategic cost reduction plan aims to optimize operations and improve financial health, positioning the company for sustainable profitability.
Negative Factors
High Leverage
High leverage increases financial risk and limits flexibility, potentially impacting the company's ability to invest in growth or weather economic downturns.
Negative Cash Flow
Negative cash flow poses liquidity challenges and may hinder the company's ability to fund operations and growth initiatives without external financing.
Profitability Challenges
Ongoing profitability issues suggest difficulties in achieving sustainable earnings, which could affect long-term viability and investor confidence.

Cytosorbents (CTSO) vs. SPDR S&P 500 ETF (SPY)

Cytosorbents Business Overview & Revenue Model

Company DescriptionCytosorbents Corporation engages in the research, development, and commercialization of medical devices with its blood purification technology platform incorporating a proprietary adsorbent and porous polymer technology. Its flagship product is CytoSorb, an extracorporeal cytokine filter for adjunctive therapy in the treatment of sepsis, adjunctive therapy in other critical care applications, prevention and treatment of perioperative complications of cardiopulmonary bypass surgery, and maintaining or enhancing the quality of solid organs harvested from donors for organ transplant. The company also develops VetResQ, a device for adjunctive therapy in the treatment of sepsis, pancreatitis, and other critical illnesses in animals; CytoSorb-XL, a device for adjunctive therapy in the treatment of sepsis and other critical illnesses; HemoDefend blood purification technology platform to reduce contaminants in the blood supply that can cause transfusion reactions or disease when administering blood and blood products to patients, as well as removal of anti-A and anti-B blood group antibodies from fresh whole blood and plasma; K+ontrol for treatment of severe hyperkalemia in patients with life-threatening conditions; and ContrastSorb for the removal of IV contrast in blood administered during CT imaging, an angiogram, or during a vascular interventional radiology procedure to reduce the risk of contrast-induced nephropathy. In addition, it is involved in the development of BetaSorb, a device for the prevention and treatment of health complications caused by the accumulation of metabolic toxins in patients with chronic renal failure; DrugSorb, a device to remove toxic chemicals from the blood; and DrugSorb-ATR, an antithrombotic removal system. The company was formerly known as MedaSorb Technologies Corporation and changed its name to Cytosorbents Corporation in May 2010. Cytosorbents Corporation was founded in 1997 and is headquartered in Princeton, New Jersey.
How the Company Makes MoneyCytosorbents generates revenue primarily through the sale of its CytoSorb devices and related products to hospitals and healthcare providers. The company employs a direct sales model in certain markets, while also working with distributors and partners to expand its reach. Key revenue streams include the sale of disposable CytoSorb cartridges, which are used in conjunction with the device for blood purification during critical care treatments. The company has established significant partnerships with medical institutions and research organizations, which not only enhance its product visibility but also facilitate clinical studies that can lead to broader adoption of its technologies. Additionally, Cytosorbents may explore opportunities for reimbursement from healthcare payers, further contributing to its earnings potential.

Cytosorbents Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
Next Earnings Date:Mar 05, 2026
Earnings Call Sentiment Neutral
The earnings call highlighted strong revenue growth and gross margin improvements, as well as strategic steps towards achieving profitability and regulatory progress in the U.S. However, challenges persist with declining sales in Germany and an increased net loss. The overall sentiment is cautiously optimistic as the company addresses these issues.
Q3-2025 Updates
Positive Updates
Record Core Product Sales
Trailing 12-month core product sales reached a record $37 million as of September 30, 2025, supported by strong execution across the global network.
Gross Margin Improvement
Gross margin remained strong at approximately 70%, an improvement from 61% in the third quarter of 2024.
Revenue Growth
Third quarter revenue was $9.5 million, up 10% from $8.6 million a year ago, or 4% on a constant currency basis.
Regulatory Progress for DrugSorb-ATR
Filed a formal pre-submission meeting request with the FDA on November 7, 2025, and anticipates a pre-submission meeting in late 2025 or early Q1 of '26.
Cost Reduction and Strategic Workforce Program
Implemented a strategic workforce and cost reduction program, including a 10% workforce reduction, to achieve cash flow breakeven by Q1 2026.
Negative Updates
Decline in German Market
Direct sales in Germany declined modestly by 3% to $12.6 million, prompting a restructuring of the sales team and approach.
Operating Loss
Q3 operating loss was approximately $9.2 million, compared to $4.8 million in the prior year.
Net Loss Increase
Net loss was $3.2 million for the quarter or $0.05 per share, compared to a net loss of $2.8 million or $0.05 per share in the prior year.
Company Guidance
In the third quarter of 2025, CytoSorbents Corp. reported a revenue of $9.5 million, marking a 10% increase from $8.6 million in the previous year, or 4% on a constant currency basis. The company's trailing 12-month core product sales reached a record $37 million as of September 30, 2025. Gross margin rose to approximately 70%, compared to 61% in the third quarter of 2024. Distributor and partner sales grew by 14% to $15.6 million, while direct sales outside of Germany increased by 24% to $8.8 million. However, sales in Germany declined by 3% to $12.6 million. Overall sales growth was 9%, or 17% when excluding Germany. The company has implemented a strategic workforce and cost reduction program, including a 10% workforce reduction, to achieve cash flow breakeven by Q1 2026. Operating expenses decreased by 6% to $9.5 million, with a net loss of $3.2 million for the quarter. CytoSorbents has also amended its loan agreement with Avenue Partners, securing $2.5 million in new capital and extending the interest-only period.

Cytosorbents Financial Statement Overview

Summary
Cytosorbents is facing significant financial challenges with consistent losses and high leverage. While there is some revenue growth and strong gross profit margins, the company's profitability and cash flow positions are concerning. High debt levels and negative cash flows highlight potential risks, necessitating strategic adjustments to improve financial health.
Income Statement
45
Neutral
Cytosorbents has shown a slight improvement in revenue growth with a TTM growth rate of 2.37%. However, the company continues to face significant profitability challenges, as indicated by negative net profit and EBIT margins. The gross profit margin remains strong at 72.57%, suggesting efficient cost management at the production level, but overall profitability is hindered by high operating expenses.
Balance Sheet
40
Negative
The company's balance sheet reflects high leverage with a debt-to-equity ratio of 2.34, indicating a reliance on debt financing. The return on equity is negative, highlighting ongoing losses. The equity ratio stands at 24.14%, suggesting a moderate level of equity financing relative to total assets, but the high debt levels pose a risk to financial stability.
Cash Flow
35
Negative
Cytosorbents is experiencing negative operating and free cash flows, with a declining free cash flow growth rate of -24.67% in the TTM period. The operating cash flow to net income ratio is close to 1, indicating that cash flow generation is in line with net losses, but the overall cash flow situation remains weak, posing liquidity challenges.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue33.48M35.59M31.08M34.69M40.11M39.45M
Gross Profit24.30M25.13M21.95M20.73M29.06M28.40M
EBITDA-19.14M-15.22M-27.88M-30.00M-21.62M-9.71M
Net Income-9.75M-20.72M-29.25M-32.81M-24.56M-7.84M
Balance Sheet
Total Assets47.99M47.37M53.26M63.23M89.52M89.95M
Cash, Cash Equivalents and Short-Term Investments10.20M3.28M14.13M22.14M52.14M71.42M
Total Debt27.06M26.89M18.31M18.25M13.82M1.03M
Total Liabilities36.40M36.26M29.99M27.86M26.94M10.73M
Stockholders Equity11.59M11.11M23.28M35.38M62.58M79.22M
Cash Flow
Free Cash Flow-10.29M-14.71M-22.59M-34.69M-18.29M-7.29M
Operating Cash Flow-9.78M-14.43M-21.66M-28.23M-14.01M-5.61M
Investing Cash Flow-601.55K-669.43K-936.24K-6.46M-4.28M-1.68M
Financing Cash Flow6.90M9.33M14.47M4.96M715.20K66.35M

Cytosorbents Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.66
Price Trends
50DMA
0.87
Negative
100DMA
0.94
Negative
200DMA
0.98
Negative
Market Momentum
MACD
-0.06
Positive
RSI
27.46
Positive
STOCH
22.88
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CTSO, the sentiment is Negative. The current price of 0.66 is below the 20-day moving average (MA) of 0.77, below the 50-day MA of 0.87, and below the 200-day MA of 0.98, indicating a bearish trend. The MACD of -0.06 indicates Positive momentum. The RSI at 27.46 is Positive, neither overbought nor oversold. The STOCH value of 22.88 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CTSO.

Cytosorbents Risk Analysis

Cytosorbents disclosed 39 risk factors in its most recent earnings report. Cytosorbents reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cytosorbents Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
$103.88M-20.783.64%16.88%
64
Neutral
$70.96M-5.71%-13.79%-132.21%
59
Neutral
$92.82M13.304.34%3.36%-21.15%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
50
Neutral
$96.28M-1.97-94.03%-20.10%7.87%
48
Neutral
$88.66M-2.52-87.61%14.04%-0.65%
38
Underperform
$49.66M-4.34-96.15%-8.97%47.29%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CTSO
Cytosorbents
0.66
-0.27
-29.03%
FONR
Fonar
14.71
-0.16
-1.08%
NSPR
InspireMD
2.11
-0.48
-18.53%
XTNT
Xtant Medical Holdings
0.65
0.22
51.16%
SRTS
Sensus Healthcare
4.32
-4.09
-48.63%
HYPR
Hyperfine
1.15
0.31
36.90%

Cytosorbents Corporate Events

CytoSorbents Reports Strong Q3 2025 Growth and Strategic Advances
Nov 14, 2025

CytoSorbents Corporation is a company specializing in blood purification technologies, primarily used in intensive care units and cardiac surgery to treat life-threatening conditions. In its third-quarter 2025 financial report, CytoSorbents announced a 10% year-over-year revenue increase, reaching $9.5 million, driven by strong performance in distributor territories and direct sales outside Germany. The company also reported an improved gross margin of 70% and a reduced operating loss of $2.9 million compared to the previous year.

Cytosorbents Corp’s Latest Study Update: A Game Changer in Critical Care?
Oct 27, 2025

Study Overview: The CytOSorb TreatMent Of Critically Ill PatientS Registry is an international observational study aimed at creating a comprehensive data repository to monitor the use of the CytoSorb device in real-world critical care settings. This registry seeks to enhance the quality of patient care by providing a scientifically-based resource for measuring and improving treatment outcomes in conditions such as septic shock, acute respiratory distress syndrome, and more.

CytoSorbents’ STAR Registry: A Closer Look at the Latest Clinical Study Update
Oct 27, 2025

The Safe and Timely Antithrombotic Removal (STAR) Registry is an international observational study conducted by CytoSorbents Corp. Its primary aim is to document real-world clinical use and outcomes of the CytoSorb device, specifically for removing antithrombotic agents in acute hospital settings. This study is significant as it addresses critical conditions such as surgical and postoperative hemorrhage, providing insights into the device’s effectiveness and safety.

Delistings and Listing ChangesRegulatory Filings and Compliance
Cytosorbents Faces Nasdaq Non-Compliance Notice
Negative
Oct 3, 2025

On October 2, 2025, CytoSorbents Corporation received a notice from Nasdaq for non-compliance with the Minimum Bid Price Requirement, as its stock price remained below $1.00 for 30 consecutive business days. The company has until March 31, 2026, to regain compliance by ensuring its stock price meets or exceeds $1.00 for at least 10 consecutive days. Failure to comply could lead to an additional compliance period if an acceptable plan is presented to Nasdaq. The company is actively monitoring its stock price and exploring options to meet the requirement.

The most recent analyst rating on (CTSO) stock is a Hold with a $1.00 price target. To see the full list of analyst forecasts on Cytosorbents stock, see the CTSO Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 14, 2025