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Cytosorbents Corp (CTSO)
NASDAQ:CTSO
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Cytosorbents (CTSO) AI Stock Analysis

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CTSO

Cytosorbents

(NASDAQ:CTSO)

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Neutral 44 (OpenAI - 5.2)
Rating:44Neutral
Price Target:
$0.35
▼(-3.06% Downside)
Action:Reiterated
Date:07/07/26
CTSO scores low primarily due to weak financial strength—ongoing losses, real cash burn, and high leverage with compressed equity. Technicals also weigh on the score given the sustained downtrend and negative momentum. Offsetting factors include strong gross margins, signs of operational improvement discussed on the earnings call, and continued regulatory progress, but limited liquidity and listing-risk headlines keep the overall score constrained.
Positive Factors
High Gross Margins
Sustained ~70% gross margins indicate durable product-level economics for the single-use cartridge model. High margins give the company structural leverage to convert incremental volume into profit as fixed costs are cut and commercialization scales, supporting longer-term path to positive cash flow.
Negative Factors
Extremely High Leverage
Debt-to-equity of ~8.6x and materially compressed equity sharply reduce financial flexibility. Elevated leverage increases refinancing, covenant and distress risk if cash generation stalls, constraining the company's ability to invest in trials, commercialization or to cushion regulatory delays over the next several quarters.
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Positive Factors
Negative Factors
High Gross Margins
Sustained ~70% gross margins indicate durable product-level economics for the single-use cartridge model. High margins give the company structural leverage to convert incremental volume into profit as fixed costs are cut and commercialization scales, supporting longer-term path to positive cash flow.
Read all positive factors

Cytosorbents (CTSO) vs. SPDR S&P 500 ETF (SPY)

Cytosorbents Business Overview & Revenue Model

Company Description
Cytosorbents Corporation specializes in creating and bringing to market innovative medical devices. Their core expertise lies in a unique blood purification platform, built upon a proprietary adsorbent and porous polymer technology. The company's ...
How the Company Makes Money
Cytosorbents primarily makes money by selling its blood purification cartridges and related therapy products to hospitals and healthcare providers, with revenue recognized from product sales. The company’s key commercial revenue stream is CytoSorb...

Cytosorbents Earnings Call Summary

Earnings Call Date:May 13, 2026
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Aug 06, 2026
Earnings Call Sentiment Positive
The call balanced operational and commercial progress against near‑term financial and regulatory challenges. Positives include modest top-line growth, strong international direct momentum (+13% YoY), healthy gross margins (69%), improved adjusted profitability metrics, strengthening clinical evidence (STAR-T showing >50% reduction in severe bleeding), and clearer regulatory direction with two FDA breakthrough designations. Main negatives are the widened GAAP net loss driven by FX, lower cash balance (~$6.4M), a delayed de novo submission requiring additional mechanistic studies and resources (likely pushing approval into late 2026/early 2027), Germany market softness, and a $0.5M order disruption tied to geopolitical events. Overall, management is executing cost reductions and targeting operating cash flow breakeven in H2 2026, and the call conveyed cautious optimism despite the identified risks.
Positive Updates
Modest Revenue Growth
Q1 2026 revenue of $8.9 million, up 2% year-over-year (down 7% on a constant currency basis), demonstrating resilience amid external headwinds.
Negative Updates
Widening GAAP Net Loss and FX Impact
GAAP net loss increased to $5.1 million ($0.08/share) in Q1 2026 from $1.5 million ($0.02/share) prior year, primarily due to noncash foreign currency transaction impacts.
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Q1-2026 Updates
Negative
Modest Revenue Growth
Q1 2026 revenue of $8.9 million, up 2% year-over-year (down 7% on a constant currency basis), demonstrating resilience amid external headwinds.
Read all positive updates
Company Guidance
Management reiterated near-term and medium-term targets: Q1 revenue was $8.9M (+2% YoY, -7% constant currency) with International Direct up ~13% YoY, building on 2025 core product sales of >$37M and >300,000 devices used in >70 countries; gross margin was 69% (vs 71% a year ago) after intentional production cuts to reduce inventory to $4.8M (from $5.3M); operating expenses fell to $9.2M (from $10.1M), producing an operating loss of $3.0M (≈22% improvement vs $3.9M) while net loss widened to $5.1M ($0.08/share) largely due to FX effects but adjusted net loss improved to $3.4M ($0.05/share) and adjusted EBITDA loss narrowed to $2.2M (from $2.7M); cash was $6.4M at March 31 (vs $7.8M YE) with total cash burn of $1.1M excl. $300K restructuring, headcount reduced ~10% in Q4’25, and ~$0.5M of distributor orders delayed in the Middle East; regulatory guidance: DrugSorb‑ATR de novo filing is now expected late‑2026/early‑2027 (typical ~150‑day review), a DOAC pre‑submission will be filed within ~30 days, STAR‑T showed >50% reduction in composite severe bleeding for ticagrelor removal, PuriFi pumps placed >100, and management is targeting operating cash‑flow breakeven in H2 2026 and a U.S. DrugSorb‑ATR TAM of $500M–$1B.

Cytosorbents Financial Statement Overview

Summary
Fundamentals are improving but remain weak overall: revenue has re-accelerated and gross margin is strong (~71% TTM), yet profitability is still materially negative (TTM net margin ~-32%) with persistent cash burn (TTM operating cash flow about -$10.1M). The balance sheet is the biggest risk, with high leverage (debt-to-equity ~8.6x) and compressed equity, limiting financial flexibility.
Income Statement
28
Negative
Balance Sheet
18
Very Negative
Cash Flow
22
Negative
BreakdownTTMDec 2025Mar 2025Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue37.20M37.06M35.59M31.08M34.69M40.11M
Gross Profit26.41M26.49M24.89M21.95M20.73M29.06M
EBITDA-7.78M-4.36M-19.27M-27.88M-30.00M-24.17M
Net Income-11.85M-8.20M-20.72M-29.25M-32.81M-24.56M
Balance Sheet
Total Assets40.56M44.18M47.37M53.26M63.23M89.52M
Cash, Cash Equivalents and Short-Term Investments4.81M6.25M3.28M14.13M22.14M52.14M
Total Debt18.96M29.11M26.89M18.31M18.25M13.82M
Total Liabilities38.37M38.28M36.26M29.99M27.86M26.94M
Stockholders Equity2.19M5.90M11.11M23.28M35.37M62.58M
Cash Flow
Free Cash Flow-10.20M-12.54M-14.71M-22.59M-34.69M-18.29M
Operating Cash Flow-10.07M-12.38M-14.43M-21.66M-28.23M-14.01M
Investing Cash Flow-413.76K-415.00K-669.43K-936.24K-6.46M-4.28M
Financing Cash Flow2.48M9.31M9.33M14.47M4.96M715.20K

Cytosorbents Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.36
Price Trends
50DMA
0.42
Negative
100DMA
0.52
Negative
200DMA
0.62
Negative
Market Momentum
MACD
-0.02
Negative
RSI
42.76
Neutral
STOCH
6.67
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CTSO, the sentiment is Negative. The current price of 0.36 is below the 20-day moving average (MA) of 0.38, below the 50-day MA of 0.42, and below the 200-day MA of 0.62, indicating a bearish trend. The MACD of -0.02 indicates Negative momentum. The RSI at 42.76 is Neutral, neither overbought nor oversold. The STOCH value of 6.67 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CTSO.

Cytosorbents Risk Analysis

Cytosorbents disclosed 39 risk factors in its most recent earnings report. Cytosorbents reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cytosorbents Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$49.33M-2.93179.24%-44.27%-0.39%
47
Neutral
$32.67M-0.92-1344.47%13.48%43.42%
45
Neutral
$8.11M-0.41-211.73%8.92%17.50%
44
Neutral
$22.68M-1.94-165.13%7.72%34.39%
44
Neutral
$54.86M-3.36836.32%31.90%-10.81%
44
Neutral
$43.48M-1.05-81.48%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CTSO
Cytosorbents
0.36
-0.55
-60.48%
ECOR
Electrocore
6.09
-1.17
-16.07%
TELA
TELA Bio
0.73
-1.12
-60.59%
MDAI
Spectral AI
1.55
-0.87
-35.95%
ICCM
Icecure Medical
2.89
-24.71
-89.53%
BDMD
Baird Medical Investment Holdings
1.03
-0.86
-45.50%

Cytosorbents Corporate Events

Delistings and Listing ChangesRegulatory Filings and Compliance
Cytosorbents Faces Nasdaq Compliance and Delisting Risk
Negative
Jul 6, 2026
On June 29, 2026, CytoSorbents Corporation received a notice from Nasdaq that it was out of compliance with Listing Rule 5550(b)(2), as its market value of listed securities had fallen below the $35 million threshold required for continued listing...
Business Operations and StrategyRegulatory Filings and Compliance
CytoSorbents Advances FDA Pathway for DrugSorb Programs
Positive
Jun 25, 2026
On June 24, 2026, CytoSorbents presented at the 2026 Life Sciences Forum and disclosed that it has scheduled two FDA pre-submission meetings in August 2026 to discuss its ticagrelor and direct oral anticoagulant programs, a key step toward potenti...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jul 07, 2026