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Transcenta Holding Limited (HK:6628)
:6628
Hong Kong Market
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Transcenta Holding Limited (6628) AI Stock Analysis

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HK:6628

Transcenta Holding Limited

(6628)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
HK$2.50
▼(-29.97% Downside)
The overall stock score reflects significant financial and valuation challenges. The company's financial performance is weak, with declining revenue and persistent losses. Technical analysis indicates bearish momentum, and the valuation metrics highlight substantial risks due to unprofitability. These factors collectively suggest a cautious outlook for the stock.

Transcenta Holding Limited (6628) vs. iShares MSCI Hong Kong ETF (EWH)

Transcenta Holding Limited Business Overview & Revenue Model

Company DescriptionTranscenta Holding Limited, a clinical stage biopharmaceutical company, engages in the discovery, research, development, manufacture, and commercialization of various drugs in the People's Republic of China and the United States. The company develops MSB2311, a humanized PD-L1 monoclonal antibody (mAb) candidate for TMB-H solid tumors; TST001, a humanized claudin 18.2 mAb candidate for solid tumors, such as gastric cancer and is under Phase II clinical trial; TST005, a PD-L1/TGF-ß bi-functional antibody candidate which is under Phase Ia clinical trial for solid tumors, including certain lung cancers; TST010, an antibody candidate targeting regulatory T cells to enhance T cell mediated tumor killing;TST002 (Blosozumab), a humanized sclerostin mAb candidate for osteoporosis; and TST004, a humanized mannan-binding lectin serine protease 2 (MASP 2) mAb candidate for IgA kidney diseases. It also develops TST003, an antibody candidate targeting a novel immune regulatory protein produced by tumor-associated fibroblasts or tumor cells with mesenchymal phenotype; TST006, a bi-specific claudin 18.2/PD-L1 antibody; TST008, a tri-functional antibody combining a MASP2 antibody fused with a truncated transmembrane activator and CAML interactor protein; MSB0254, a humanized VEGFR-2 mAb candidate for solid tumors and is under Phase Ib/IIa clinical trials; and MSB2311, A humanized PD-L1 mAb Candidate for solid tumors and is under Phase Ib/IIa clinical trials Transcenta Holding Limited has collaboration agreements with Eli Lilly and Company, Alebund Pharmaceuticals, and Merck. The company was formerly known as MabSpace International Limited and changed its name to Transcenta Holding Limited in June 2019. Transcenta Holding Limited was incorporated in 2010 and is headquartered in Suzhou, the People's Republic of China.
How the Company Makes MoneyTranscenta generates revenue primarily through the development and commercialization of its biopharmaceutical products. Key revenue streams include sales from approved drugs, licensing agreements with other pharmaceutical companies, and collaborations for research and development initiatives. The company may also earn revenue through milestone payments and royalties associated with its partnered products. Significant partnerships with larger pharmaceutical firms can enhance its financial stability and provide additional resources for product development, thus contributing to its overall earnings.

Transcenta Holding Limited Financial Statement Overview

Summary
Transcenta Holding Limited faces significant financial challenges across all verticals. The income statement shows declining revenue and persistent losses, while the balance sheet reflects moderate leverage but poor returns on equity. Cash flow issues are evident, with negative growth and cash burn. Overall, the company needs to address its operational inefficiencies and improve its financial health to achieve sustainable growth.
Income Statement
30
Negative
The income statement reveals significant challenges, with negative growth and profitability metrics. The TTM data shows a decline in revenue by 8.97%, and the net profit margin is deeply negative at -25.78%. The EBIT and EBITDA margins are also negative, indicating operational inefficiencies. Despite a consistent gross profit margin around 35.5%, the overall financial health is weak due to substantial losses.
Balance Sheet
40
Negative
The balance sheet shows moderate leverage with a debt-to-equity ratio of 0.33, which is relatively stable. However, the return on equity is negative, indicating that the company is not generating profits from its equity base. The equity ratio is not explicitly provided, but the overall financial position suggests a need for improved profitability and asset management.
Cash Flow
35
Negative
Cash flow analysis highlights ongoing cash burn, with negative operating and free cash flows. The free cash flow growth rate is negative at -10.48% in the TTM period, and the operating cash flow to net income ratio is also negative, reflecting cash flow challenges. The free cash flow to net income ratio is slightly above 1, indicating that cash outflows are closely aligned with net losses.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue9.41M11.26M53.85M101.89M50.24M80.98M
Gross Profit3.27M4.00M14.40M19.89M9.37M18.20M
EBITDA-211.90M-233.12M-393.01M-334.09M-1.65B-264.81M
Net Income-266.36M-290.29M-462.57M-406.75M-1.72B-316.63M
Balance Sheet
Total Assets1.04B1.20B1.69B2.13B2.54B2.09B
Cash, Cash Equivalents and Short-Term Investments45.81M169.42M546.03M895.45M1.22B813.59M
Total Debt210.14M250.61M409.63M411.46M364.71M254.30M
Total Liabilities386.57M448.64M665.67M660.64M579.39M2.91B
Stockholders Equity652.13M751.64M1.03B1.47B1.97B-816.25M
Cash Flow
Free Cash Flow-175.14M-216.15M-373.80M-318.03M-457.84M-237.73M
Operating Cash Flow-170.07M-213.83M-358.04M-295.81M-384.50M-174.40M
Investing Cash Flow8.23M14.28M57.47M-102.61M-69.77M-57.74M
Financing Cash Flow-157.75M-178.06M-47.20M26.72M879.71M620.17M

Transcenta Holding Limited Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.57
Price Trends
50DMA
3.63
Negative
100DMA
3.41
Negative
200DMA
2.38
Positive
Market Momentum
MACD
-0.24
Negative
RSI
35.19
Neutral
STOCH
27.88
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:6628, the sentiment is Negative. The current price of 3.57 is above the 20-day moving average (MA) of 2.89, below the 50-day MA of 3.63, and above the 200-day MA of 2.38, indicating a neutral trend. The MACD of -0.24 indicates Negative momentum. The RSI at 35.19 is Neutral, neither overbought nor oversold. The STOCH value of 27.88 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:6628.

Transcenta Holding Limited Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
HK$1.48B181.900.99%9.41%-32.69%
52
Neutral
HK$2.80B-2.6979.98%-3.40%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
HK$2.21B-55.33%-100.00%30.68%
41
Neutral
HK$1.16B-34.18%-57.84%24.58%
40
Neutral
HK$849.74M83.89%
36
Underperform
HK$815.90M-4.26-54.87%81.67%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:6628
Transcenta Holding Limited
2.62
1.89
258.90%
HK:9939
Kintor Pharmaceutical Ltd
2.01
0.95
89.62%
HK:1875
TOT BIOPHARM International Co. Ltd.
1.80
-0.08
-4.26%
HK:2197
Clover Biopharmaceuticals Ltd.
2.50
2.22
792.86%
HK:2257
Sirnaomics Ltd.
8.00
5.47
216.21%
HK:3681
SinoMab Bioscience Ltd.
1.62
0.54
50.00%

Transcenta Holding Limited Corporate Events

Transcenta’s Partner Inhibrx Reports Positive Phase 2 Results for Ozekibart in Chondrosarcoma
Oct 30, 2025

Transcenta Holding Limited announced that its partner, Inhibrx Biosciences, has reported positive Phase 2 results for ozekibart in treating chondrosarcoma, a cancer with no approved systemic options. The promising results from the ChonDRAgon study highlight ozekibart’s potential as a significant treatment option, with plans for a Biologics License Application submission by 2026. This development strengthens Transcenta’s position in the oncology sector, particularly in regions where it holds exclusive commercialization rights.

The most recent analyst rating on (HK:6628) stock is a Sell with a HK$3.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Advances Financial and Strategic Initiatives to Strengthen Position
Oct 22, 2025

Transcenta Holding Limited has made significant progress in addressing the disclaimer of opinion in its 2024 annual report by implementing key measures to strengthen its financial position and enhance liquidity. The company is actively engaging with global and regional partners for the development and commercialization of its major pipeline assets, pursuing out-licensing and fundraising opportunities, and exploring innovative financing models to support its research and development efforts. These actions are expected to improve the company’s operational capabilities and strategic positioning in the biotechnology industry.

The most recent analyst rating on (HK:6628) stock is a Hold with a HK$4.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Explores Blockchain-Based Financing for Oncology Innovations
Sep 22, 2025

Transcenta Holding Limited has announced a strategic collaboration with IVD Medical Holding Limited and its subsidiaries to explore the issuance of Real-World Asset Tokens on the Ethereum blockchain. This innovative financing strategy, enabled by regulatory reforms in the U.S. and China, aims to fund the accelerated development of several oncology treatments, potentially democratizing investment opportunities in biotechnology and enhancing the company’s industry positioning.

The most recent analyst rating on (HK:6628) stock is a Hold with a HK$3.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Completes HK$59.34 Million Share Placement
Sep 17, 2025

Transcenta Holding Limited has successfully completed the placement of 14,400,000 new shares under a general mandate, raising approximately HK$59.34 million. This strategic move, facilitated by BOCI Asia Limited, aims to strengthen the company’s financial position and potentially enhance its market presence, with the new shares being issued to independent third-party investors.

The most recent analyst rating on (HK:6628) stock is a Hold with a HK$3.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Holding Limited Announces New Share Placement to Raise HK$59.34 Million
Sep 9, 2025

Transcenta Holding Limited has announced a new share placement under a general mandate, involving the issuance of 14,400,000 shares, representing about 3.31% of the current total shares. The placement, coordinated by BOCI Asia Limited, is priced at a discount to recent market prices, aiming to raise approximately HK$59.34 million in net proceeds. This strategic move is intended to strengthen the company’s financial position and support its operational goals, although completion is contingent on certain conditions being met.

The most recent analyst rating on (HK:6628) stock is a Hold with a HK$3.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Reports Interim Results with Strategic Adjustments
Aug 27, 2025

Transcenta Holding Limited announced its interim results for the six months ended June 30, 2025, revealing a decrease in revenue primarily due to a decline in CDMO services. Despite this, the company saw an increase in other income from government subsidies and a reduction in research and development expenses, which contributed to a decrease in overall losses. The company’s strategic reprioritization of resources and pipeline advancement efforts were highlighted as key factors in the financial performance during this period.

The most recent analyst rating on (HK:6628) stock is a Hold with a HK$3.00 price target. To see the full list of analyst forecasts on Transcenta Holding Limited stock, see the HK:6628 Stock Forecast page.

Transcenta Holding Limited Schedules Board Meeting to Review Interim Results
Aug 15, 2025

Transcenta Holding Limited has announced a board meeting scheduled for August 27, 2025, to review and approve the interim financial results for the first half of the year ending June 30, 2025. The meeting will also consider the recommendation of an interim dividend, indicating a potential return to shareholders and reflecting on the company’s financial health and strategic direction.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 08, 2025