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Zhaoke Ophthalmology Ltd. (HK:6622)
:6622
Hong Kong Market
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Zhaoke Ophthalmology Ltd. (6622) AI Stock Analysis

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HK:6622

Zhaoke Ophthalmology Ltd.

(6622)

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Neutral 47 (OpenAI - 5.2)
Rating:47Neutral
Price Target:
HK$2.50
▼(-21.14% Downside)
Action:Reiterated
Date:04/28/26
The score is primarily held back by persistent losses, unstable revenue trends, negative gross profit in 2025, and ongoing cash burn, which together imply continued funding and execution risk. Technical indicators add a modest headwind with the stock trading below key longer-term moving averages and weak momentum. A relatively moderate leverage profile and sizeable equity provide some support, but not enough to offset the operating and cash flow weakness.
Positive Factors
Focused ophthalmology franchise
A dedicated ophthalmology focus creates a durable specialization: concentrated R&D expertise, deeper clinical/regulatory know-how, and a clearer commercial go-to-market for eye therapies. In‑licensing plus internal development broadens the product funnel and reduces sole dependence on single candidates.
Negative Factors
Persistent operating losses
Sustained operating losses indicate the business has not yet demonstrated a scalable, profitable model. Continued deficits will erode equity, force recurring financing, and constrain reinvestment in R&D or commercialization, raising structural execution and dilution risks over the next several quarters.
Read all positive and negative factors
Positive Factors
Negative Factors
Focused ophthalmology franchise
A dedicated ophthalmology focus creates a durable specialization: concentrated R&D expertise, deeper clinical/regulatory know-how, and a clearer commercial go-to-market for eye therapies. In‑licensing plus internal development broadens the product funnel and reduces sole dependence on single candidates.
Read all positive factors

Zhaoke Ophthalmology Ltd. (6622) vs. iShares MSCI Hong Kong ETF (EWH)

Zhaoke Ophthalmology Ltd. Business Overview & Revenue Model

Company Description
Zhaoke Ophthalmology Limited is an ophthalmic pharmaceutical company dedicated to researching, developing, and commercializing therapeutic solutions addressing significant unmet medical requirements in the People's Republic of China. The company i...
How the Company Makes Money
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Zhaoke Ophthalmology Ltd. Financial Statement Overview

Summary
Financial profile is weak overall: income statement remains deeply loss-making with 2025 revenue declining and gross profit turning negative, while cash flow shows sustained operating cash burn and negative free cash flow. The main offset is a relatively supportive balance sheet with modest leverage and sizable equity, though continued losses risk erosion over time.
Income Statement
18
Very Negative
Balance Sheet
62
Positive
Cash Flow
24
Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue31.15M69.32M18.75M0.000.00
Gross Profit-32.57M51.80M14.25M0.000.00
EBITDA-215.45M-251.23M-327.86M-384.55M-377.53M
Net Income-203.57M-237.49M-385.04M-407.32M-2.13B
Balance Sheet
Total Assets1.94B2.24B2.42B2.57B2.61B
Cash, Cash Equivalents and Short-Term Investments1.30B1.19B1.46B1.73B2.14B
Total Debt292.48M238.59M238.03M131.93M37.03M
Total Liabilities359.58M343.44M372.02M222.25M109.92M
Stockholders Equity1.58B1.90B2.05B2.35B2.50B
Cash Flow
Free Cash Flow-265.04M-297.79M-418.93M-569.60M-339.63M
Operating Cash Flow-260.20M-253.72M-323.66M-331.05M-245.14M
Investing Cash Flow109.11M-116.45M-75.77M-324.57M683.52M
Financing Cash Flow45.63M-12.12M99.29M76.23M1.66B

Zhaoke Ophthalmology Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price3.17
Price Trends
50DMA
2.73
Negative
100DMA
2.98
Negative
200DMA
3.17
Negative
Market Momentum
MACD
-0.05
Positive
RSI
47.50
Neutral
STOCH
38.47
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HK:6622, the sentiment is Negative. The current price of 3.17 is above the 20-day moving average (MA) of 2.60, above the 50-day MA of 2.73, and below the 200-day MA of 3.17, indicating a bearish trend. The MACD of -0.05 indicates Positive momentum. The RSI at 47.50 is Neutral, neither overbought nor oversold. The STOCH value of 38.47 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HK:6622.

Zhaoke Ophthalmology Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
HK$4.15B-20.00-4.33%93.26%49.38%
47
Neutral
HK$1.42B-5.88-12.64%-53.85%12.23%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HK:6622
Zhaoke Ophthalmology Ltd.
2.61
0.09
3.57%
HK:1477
Ocumension Therapeutics
5.09
-4.00
-44.00%

Zhaoke Ophthalmology Ltd. Corporate Events

Zhaoke Ophthalmology’s Myopia Drug NVK002 Accepted for Australian TGA Evaluation
Jun 15, 2026
Zhaoke Ophthalmology Limited announced that Australia’s Therapeutic Goods Administration has accepted for evaluation its registration application for Atropine Sulfate Eye Drops (0.02% strength), known as NVK002, intended to slow myopia progr...
Zhaoke Ophthalmology Launches HK$100 Million Share Buy-Back Plan
Jun 8, 2026
Zhaoke Ophthalmology has approved a 12-month on-market share repurchase plan of up to HK$100 million, allowing it to buy back up to 10% of its issued shares under an existing shareholder mandate. The repurchased shares will be cancelled, and the c...
Zhaoke Ophthalmology Strikes Indonesia Distribution Deal for Dry Eye Gel
Jun 5, 2026
Zhaoke Ophthalmology has signed an exclusive distribution and supply agreement with Indonesian drug maker PT Erlangga Edi Laboratories to commercialize its CsA Ophthalmic Gel for moderate-to-severe dry eye disease in Indonesia. Under the deal, PT ...
Zhaoke Ophthalmology Shareholders Approve All Resolutions at 2026 AGM
May 15, 2026
Zhaoke Ophthalmology Limited reported that all resolutions proposed at its annual general meeting held on May 15, 2026 were approved by shareholders by way of poll. Investors granted the board mandates to repurchase up to 10% of issued shares, iss...
Zhaoke Ophthalmology Renews Related-Party CMO Deal for Eyprotor
Apr 30, 2026
Zhaoke Ophthalmology has renewed its contract manufacturing arrangement with related party Lee’s Pharm Hefei to secure continued production of its ophthalmic drug Eyprotor for commercial sale. The deal is structured through a supplemental ag...
Zhaoke Ophthalmology Sets 2026 AGM to Seek Share Repurchase and Issuance Mandates
Apr 23, 2026
Zhaoke Ophthalmology Limited has called its annual general meeting for May 15, 2026, in Hong Kong, where shareholders will vote on key share capital mandates. The agenda includes proposals to authorize the board to repurchase up to 10% of the comp...
Zhaoke Ophthalmology Moves to Update Articles for Hybrid Meetings and New HK Rules
Apr 15, 2026
Zhaoke Ophthalmology Limited plans to overhaul its articles of association, replacing the existing version with amended and restated articles to align with updated Hong Kong listing and regulatory standards. The move focuses on facilitating hybrid...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 28, 2026