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HCW Biologics (HCWB)
NASDAQ:HCWB
US Market

HCW Biologics (HCWB) AI Stock Analysis

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HCW Biologics

(NASDAQ:HCWB)

Rating:43Neutral
Price Target:
$4.50
▼(-7.41%Downside)
HCW Biologics has a low overall stock score primarily due to its poor financial performance and valuation. While technical analysis reflects bearish momentum, recent corporate events provide a slight positive offset by showcasing investor interest and strategic partnerships. However, the financial instability and ongoing operational challenges remain significant concerns.
Positive Factors
Clinical Trials
HCW Biologics announced the clearance of HCW9302 to enter a Phase 1 clinical trial in patients with moderate to severe alopecia areata.
Financial Performance
HCW Biologics has made considerable progress in shoring up its balance sheet and advancing its pipeline following a challenging legal issue and arbitration.
Partnerships and Collaborations
The agreement with WY Biotech provides important validation for HCW Biologics' new discovery platform and favorable economics.
Negative Factors
Capital Requirements
Despite recent capital influx, HCW Biologics has remaining legal expenses of $14.4M and may require further capital.
Stock Dilution
Dilution has led to a lower 12-month price target, reduced from $120 to $35 (split-adjusted).

HCW Biologics (HCWB) vs. SPDR S&P 500 ETF (SPY)

HCW Biologics Business Overview & Revenue Model

Company DescriptionHCW Biologics Inc. (HCWB) is a biotechnology company focused on the discovery and development of novel immunotherapies designed to delay or mitigate age-related diseases. It specializes in the development of proprietary immunotherapeutic technology platforms aimed at improving the immune system's ability to fight cancer and other chronic diseases. The company's core products involve innovative biologic molecules that target specific pathways to enhance treatment efficacy.
How the Company Makes MoneyHCW Biologics generates revenue primarily through the development and commercialization of its proprietary biologics and immunotherapy products. Key revenue streams include licensing agreements, partnerships with pharmaceutical companies, and government or private grants to support research and development. Significant partnerships with larger biotechnology and pharmaceutical firms enable HCW Biologics to leverage their platforms for wider distribution and access to established markets. The company also potentially earns milestone payments and royalties from partners who utilize its technology in their own drug development projects.

HCW Biologics Financial Statement Overview

Summary
HCW Biologics faces financial difficulties with declining revenues, high operational losses, and significant leverage. The income statement shows negative growth and profitability, the balance sheet is burdened with high debt and negative equity, while cash flow statements reflect cash burn from operations.
Income Statement
30
Negative
HCW Biologics has experienced declining revenue over the past year, with a negative revenue growth rate. The gross profit margin is positive but very low, indicating challenges in managing costs or pricing. The net profit margin is deeply negative, reflecting significant losses in operations, compounded by negative EBIT and EBITDA margins, which highlight inefficiencies in core business operations.
Balance Sheet
20
Very Negative
The company's balance sheet shows a high debt-to-equity ratio due to negative equity, indicating potential financial distress. The return on equity is also negative, reflecting losses. The equity ratio is negative, a sign of financial instability and potential risk for creditors. Overall, the balance sheet suggests significant leverage and financial challenges.
Cash Flow
35
Negative
HCW Biologics has negative operating cash flow, indicating cash burn from core operations. The free cash flow is also negative, showing cash outflows exceeding inflows. However, financing activities have provided a cash influx, slightly offsetting cash burn. The operating cash flow to net income ratio is negative, suggesting challenges in converting revenue into cash.
Breakdown
TTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
3.50M2.57M2.84M6.72M0.004.10M
Gross Profit
615.04K959.40K560.36K2.59M-543.60K4.10M
EBIT
-37.09M-29.48M-25.72M-15.08M-13.37M-5.82M
EBITDA
-36.17M-29.48M-23.58M-14.18M-12.82M-5.25M
Net Income Common Stockholders
-37.33M-30.02M-24.99M-14.72M-12.36M-5.78M
Balance SheetCash, Cash Equivalents and Short-Term Investments
7.36M4.67M3.60M32.06M36.71M8.46M
Total Assets
0.0030.24M28.51M46.81M53.51M15.40M
Total Debt
0.006.31M6.30M6.41M0.00567.31K
Net Debt
7.36M1.64M2.71M-15.92M-11.73M-7.89M
Total Liabilities
0.0037.01M15.05M9.38M2.32M1.00M
Stockholders Equity
9.00M-6.77M13.46M37.43M51.19M14.40M
Cash FlowFree Cash Flow
-19.15M-14.49M-28.72M-20.66M-11.02M-10.62M
Operating Cash Flow
-15.29M-14.23M-22.51M-10.39M-10.98M-10.43M
Investing Cash Flow
-3.86M-261.62K3.80M14.71M-35.02M-186.68K
Financing Cash Flow
8.93M15.57M-14.53K6.27M49.27M11.72M

HCW Biologics Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.86
Price Trends
50DMA
7.42
Negative
100DMA
10.74
Negative
200DMA
15.04
Negative
Market Momentum
MACD
-0.83
Positive
RSI
31.22
Neutral
STOCH
20.25
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For HCWB, the sentiment is Negative. The current price of 4.86 is below the 20-day moving average (MA) of 6.60, below the 50-day MA of 7.42, and below the 200-day MA of 15.04, indicating a bearish trend. The MACD of -0.83 indicates Positive momentum. The RSI at 31.22 is Neutral, neither overbought nor oversold. The STOCH value of 20.25 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for HCWB.

HCW Biologics Risk Analysis

HCW Biologics disclosed 48 risk factors in its most recent earnings report. HCW Biologics reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

HCW Biologics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
$5.25B3.27-44.35%6.27%16.79%-0.10%
49
Neutral
$17.96M-362.79%32.45%39.31%
49
Neutral
$9.14M-451.34%-57.84%
43
Neutral
$12.79M-9999.00%-63.20%15.71%
40
Underperform
$9.85M-59.80%157.63%40.52%
34
Underperform
$8.67M-126.03%-100.00%-27.44%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
HCWB
HCW Biologics
4.86
-35.14
-87.85%
CARM
Carisma Therapeutics
0.50
-0.51
-50.50%
APRE
Aprea Therapeutics
1.77
-2.30
-56.51%
DWTX
Dogwood Therapeutics
4.80
-1.70
-26.15%
TSBX
Turnstone Biologics Corp.
0.35
-2.39
-87.23%

HCW Biologics Corporate Events

Private Placements and Financing
HCW Biologics Sees Strong Investor Interest in June
Positive
Jun 13, 2025

On May 13, 2025, HCW Biologics Inc. entered into a Securities Purchase Agreement with Armistice Capital Master Fund Ltd., granting pre-funded warrants for up to 513,140 shares of common stock. Armistice exercised these warrants on several occasions in May and June 2025, purchasing a total of 459,140 shares, with the potential to purchase an additional 54,000 shares, indicating strong investor interest and potential capital infusion for HCW Biologics.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Delistings and Listing ChangesPrivate Placements and FinancingBusiness Operations and StrategyRegulatory Filings and Compliance
HCW Biologics Meets Nasdaq Listing Requirements in May 2025
Positive
Jun 5, 2025

In May 2025, HCW Biologics Inc. successfully met Nasdaq’s continued listing requirements by evidencing compliance with the Bid Price Rule and MVPHS Rule, following a series of financial maneuvers including a $6.6 million Senior Note Conversion and a $5.0 million equity financing. Additionally, the company completed its obligations under the WY Agreement, securing a $7.0 million upfront license fee, and suspended the Wugen License Agreement for 12 months, enhancing its financial standing and operational flexibility.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Product-Related AnnouncementsBusiness Operations and Strategy
HCW Biologics Secures Licensing Agreement with WY Biotech
Positive
Jun 4, 2025

On June 4, 2025, HCW Biologics announced that WY Biotech completed its due diligence on the technology transfer report for HCW11-006, confirming its commitment to develop and commercialize the molecule under an amended license agreement. This agreement, which includes a $7.0 million upfront licensing fee, positions HCW Biologics to receive additional milestone payments and royalties, while allowing them to opt-in for commercialization rights in certain territories after Phase 1 trials, impacting their financial and strategic positioning in the biopharmaceutical industry.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Private Placements and Financing
HCW Biologics Engages Armistice in Securities Purchase
Neutral
May 30, 2025

HCW Biologics Inc. entered into a Securities Purchase Agreement with Armistice Capital Master Fund Ltd. on May 13, 2025, which included pre-funded warrants for purchasing up to 513,140 shares of common stock. By May 29, 2025, Armistice had exercised warrants to acquire a total of 374,140 shares, leaving 139,000 shares still available for purchase, indicating a significant engagement with Armistice that could impact the company’s financial operations and market positioning.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Private Placements and Financing
HCW Biologics Issues Shares Through Warrant Exercise
Neutral
May 23, 2025

On May 13, 2025, HCW Biologics Inc. entered into a Securities Purchase Agreement with Armistice Capital Master Fund Ltd., granting pre-funded warrants for up to 513,140 shares of common stock. Following this, on May 15 and May 22, 2025, Armistice exercised some of these warrants, resulting in the issuance of 177,140 and 126,000 shares respectively, with 210,000 warrants remaining.

The most recent analyst rating on (HCWB) stock is a Buy with a $3.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Private Placements and FinancingBusiness Operations and Strategy
HCW Biologics Enters Securities Purchase Agreement
Neutral
May 20, 2025

On May 13, 2025, HCW Biologics entered into a Securities Purchase Agreement with Armistice Capital Master Fund, granting pre-funded warrants to purchase shares of common stock. Subsequently, Armistice exercised some of these warrants, resulting in the issuance of 177,140 shares. Additionally, the company converted $270,000 of unsecured convertible promissory notes into common stock, with shares issued to key executives and board members, reflecting strategic financial maneuvers to strengthen its capital structure.

The most recent analyst rating on (HCWB) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Private Placements and FinancingBusiness Operations and Strategy
HCW Biologics Closes $5 Million Public Offering
Neutral
May 15, 2025

On May 13, 2025, HCW Biologics Inc. announced the pricing of a $5.0 million follow-on public offering, involving the sale of 671,140 units consisting of shares, pre-funded warrants, and common stock warrants. The offering, which closed on May 15, 2025, aims to support the company’s preclinical and clinical development, business development, and other corporate purposes. Additionally, the company negotiated to amend existing warrants, reducing their exercise price, which could impact stakeholder value and market positioning.

The most recent analyst rating on (HCWB) stock is a Buy with a $4.00 price target. To see the full list of analyst forecasts on HCW Biologics stock, see the HCWB Stock Forecast page.

Delistings and Listing ChangesStock Split
HCW Biologics Announces Reverse Stock Split Approval
Neutral
Apr 1, 2025

On March 31, 2025, HCW Biologics’ stockholders approved a 1-for-40 reverse stock split of its common stock, which was subsequently authorized by the Board of Directors. This move, effective April 11, 2025, aims to increase the stock’s per-share bid price above $1.00 to regain compliance with Nasdaq’s listing requirements. The reverse stock split will reduce the number of outstanding shares from approximately 44.9 million to about 1.1 million, without altering the total number of authorized shares. The adjustment will affect all stockholders uniformly, with fractional shares being rounded up to the nearest whole share. The company’s operations and stakeholder interests remain largely unchanged, aside from the necessary adjustments to stock options and warrants.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.