Record-Breaking Revenue and Growth
Total revenue in Q2 2025 was $326 million, representing a 41% increase over the second quarter of the prior year. Royalty revenue grew 65% year-over-year to $206 million. Adjusted EBITDA increased 65% over the prior year second quarter to $226 million.
Raised Financial Guidance
Halozyme raised its 2025 financial guidance, now projecting total revenue of $1.275 billion to $1.355 billion, representing 26% to 33% growth over 2024. Full year royalty revenue guidance is increased to $825 million to $860 million, representing growth year-over-year of 44% to 51%.
Successful Product Launches and Approvals
New product approval for RYBREVANT subcutaneous in Europe and first-time approvals for Opdivo subcutaneous and VYVGART Hytrulo in Europe. The launch of OCREVUS ZUNOVO subcutaneous with ENHANZE is progressing well, with almost 7,000 patients treated globally.
Strong Performance of Blockbuster Products
DARZALEX second quarter revenue increased almost 22% to $3.5 billion. Phesgo's first half 2025 revenue was CHF 1.2 billion, reflecting a 55% year-over-year growth. VYVGART total sales increased 97% year-over-year in the second quarter to $949 million.
Share Repurchase Program
Completed the second $250 million share repurchase tranche of the $750 million plan and initiated the third $250 million share repurchase program.