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Renalytix (GB:RENX)
LSE:RENX

Renalytix (RENX) AI Stock Analysis

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GB

Renalytix

(LSE:RENX)

37Underperform
Renalytix's overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Despite positive corporate events suggesting strategic interest and growth potential, the technical analysis and valuation remain weak, impacting the stock's appeal.

Renalytix (RENX) vs. S&P 500 (SPY)

Renalytix Business Overview & Revenue Model

Company DescriptionRenalytix Plc develops artificial intelligence-enabled in vitro diagnostic solutions for kidney diseases. The company offers KidneyIntelX, a diagnostic platform that employs an artificial intelligence-enabled algorithm that combines various data inputs, including validated blood-based biomarkers, inherited genetics and personalized patient data from electronic health record systems to generate a unique patient risk score. Its products are used in kidney disease diagnosis and prognosis, clinical care, patient stratification for drug clinical trials, and drug target discovery. Renalytix AI plc has a license agreement with Mount Sinai Health System to develop and commercialize licensed products in connection with the application of artificial intelligence for the diagnosis of kidney disease; Joslin Diabetes Center, Inc. for developing and commercializing products for diagnosing and predicting kidney disease using biomarkers; and Kantaro Biosciences LLC for developing and commercializing laboratory tests for the detection of antibodies against SARS-CoV-2. The company also has a partnership agreement with Atrium Health, Wake Forest Baptist Health, and Wake Forest School of Medicine to implement an advanced clinical care model designed to improve kidney health and reduce kidney disease progression and kidney failure in high-risk populations. The company was formerly known as Renalytix AI plc and changed its name to Renalytix Plc in June 2021. Renalytix Plc was incorporated in 2018 and is headquartered in New York, New York.
How the Company Makes MoneyRenalytix makes money primarily through the commercialization of its KidneyIntelX diagnostic platform. The company's revenue model involves partnerships with healthcare providers, hospitals, and insurance companies to implement and integrate KidneyIntelX into their patient care systems. By offering a subscription-based or per-test pricing model, Renalytix generates revenue whenever its diagnostic solutions are utilized in clinical settings. Additionally, the company may engage in strategic collaborations with pharmaceutical companies, leveraging its technology for drug development and clinical trial support. These partnerships can provide additional revenue streams through licensing agreements, milestone payments, and data sharing arrangements.

Renalytix Financial Statement Overview

Summary
Renalytix faces significant financial challenges with declining revenues, high operating losses, and solvency concerns. The company is heavily reliant on external financing to sustain operations.
Income Statement
30
Negative
Renalytix shows declining revenue over the TTM with a significant drop from the previous year. The gross profit margin is low at 19.72%, and the net profit margin is deeply negative at -987.12%, indicating high operating losses. The company has negative EBIT and EBITDA margins, reflecting substantial operational challenges.
Balance Sheet
25
Negative
The balance sheet reveals a negative stockholders' equity, signaling potential financial distress. The debt-to-equity ratio is undefined due to negative equity, posing a risk. The equity ratio is also negative, showing liabilities exceed assets. These factors highlight solvency concerns.
Cash Flow
35
Negative
Operating cash flow and free cash flow are both significantly negative, indicating cash burn. The operating cash flow to net income ratio is positive, suggesting some cash efficiency in losses, but the free cash flow to net income ratio is negative, underscoring cash outflows exceeding income.
Breakdown
TTMJun 2024Jun 2023Jun 2022Jun 2021Jun 2020
Income StatementTotal Revenue
2.37M2.29M3.40M2.97M1.49M0.00
Gross Profit
468.00K156.00K701.00K918.00K687.00K-74.00K
EBIT
-19.19M-29.61M-42.35M-57.37M-32.61M-11.08M
EBITDA
-19.98M-28.52M-41.71M-52.69M-33.69M-11.08M
Net Income Common Stockholders
-23.43M-33.46M-45.61M-45.28M-34.73M-9.84M
Balance SheetCash, Cash Equivalents and Short-Term Investments
23.82M4.68M26.14M44.08M74.45M14.28M
Total Assets
30.66M7.97M42.12M63.26M102.58M41.30M
Total Debt
12.21M8.54M12.15M12.71M352.00K622.00K
Net Debt
-11.61M3.85M-12.53M-28.63M-64.81M-12.67M
Total Liabilities
21.77M15.83M23.66M20.09M7.48M5.34M
Stockholders Equity
8.88M-7.85M18.45M43.17M95.10M35.96M
Cash FlowFree Cash Flow
-18.16M-30.11M-32.67M-46.44M-26.26M-11.37M
Operating Cash Flow
-23.02M-30.11M-32.67M-45.74M-24.63M-10.06M
Investing Cash Flow
21.00K-4.00K0.00-694.00K-741.00K-485.00K
Financing Cash Flow
26.86M10.25M15.12M25.52M77.24M16.54M

Renalytix Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price8.25
Price Trends
50DMA
8.51
Negative
100DMA
9.80
Negative
200DMA
9.61
Negative
Market Momentum
MACD
-0.09
Negative
RSI
49.80
Neutral
STOCH
75.00
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For GB:RENX, the sentiment is Neutral. The current price of 8.25 is above the 20-day moving average (MA) of 8.06, below the 50-day MA of 8.51, and below the 200-day MA of 9.61, indicating a neutral trend. The MACD of -0.09 indicates Negative momentum. The RSI at 49.80 is Neutral, neither overbought nor oversold. The STOCH value of 75.00 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for GB:RENX.

Renalytix Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
GBCRW
72
Outperform
£689.88M59.124.50%1.50%6.74%54.83%
52
Neutral
$5.15B3.05-44.13%2.84%16.42%-0.48%
GBSAR
47
Neutral
£21.51M-87.30%71.17%
46
Neutral
£15.48M-137.62%10.50%-9.60%
37
Underperform
$27.32M425.97%-4.48%61.09%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:RENX
Renalytix
8.25
-14.25
-63.33%
GB:AGL
ANGLE plc
8.00
-13.22
-62.30%
GB:CRW
Craneware
2,210.00
60.47
2.81%
GB:SAR
Sareum Holdings
16.00
-14.75
-47.97%
GB:KOO
Kooth
133.50
-168.50
-55.79%
GB:AREC
Arecor Therapeutics PLC
41.00
-105.50
-72.01%

Renalytix Earnings Call Summary

Earnings Call Date:Mar 18, 2025
(Q3-2024)
|
% Change Since: -8.33%|
Next Earnings Date:Jun 17, 2025
Earnings Call Sentiment Neutral
The earnings call highlighted significant strategic achievements, including Medicare coverage developments, inclusion in clinical guidelines, successful fundraising, and cost reduction efforts. However, there are challenges such as a decline in revenue and testing volumes, and adoption hurdles in the VA system. The sentiment is balanced, with positive long-term strategic developments countered by short-term operational challenges.
Q3-2024 Updates
Positive Updates
Positive Medicare Coverage Developments
Medicare contractor National Government Services issued a draft local coverage determination for KidneyIntelX, with expectations for a final coverage determination in the near term.
Inclusion in International Clinical Guidelines
KidneyIntelX was included in the KDIGO international clinical guidelines for chronic kidney disease, marking a significant milestone for broader adoption.
Successful Fundraising
Completed common stock equity financing rounds in March and April, raising net proceeds of approximately $13.5 million, extending the financial runway.
FDA-Authorized Product Launch
Launched the FDA-authorized KidneyIntelX.dkd product version, with commercial test orders now being received.
Cost Reduction Achievements
Year-over-year headcount reduction of 50% and overall operating expenses reduced by approximately 40%, aiming for further expense reductions.
Direct-to-Physician Sales Growth
Achieved a 33% increase in direct-to-primary-care test order rates quarter-over-quarter, indicating early growth trends.
Strategic Acquisition Interest
Received interest from multiple potential acquirers, with a competitive sale process anticipated.
Negative Updates
Revenue Decline
Recorded revenue of $535,000 for Q3 2024, down from $724,000 in the prior year period.
Testing Volume Decrease
Processed 806 tests during the quarter, a decrease from previous quarters, with 82% being billable.
Challenges in VA System Adoption
Faced complexities in rolling out KidneyIntelX in the VA system, leading to reduced focus in this market for 2024.
Company Guidance
During the third quarter earnings call for Renalytix (Symbol: RENX.L), management provided a detailed overview of their financial and strategic progress. The company reported a revenue of $535,000 for Q3 2024, with 806 tests processed, 82% of which were billable. This reflects a decline from the previous year, attributed to the conclusion of a $6 million contract with Mount Sinai. Operating expenses were significantly reduced by 40% year-over-year to $6.5 million, following strategic reorganization efforts, including a 50% reduction in headcount. The net loss also decreased by 36% to $7.7 million. The launch of the FDA-authorized KidneyIntelX.dkd product and increased insurance reimbursement were highlighted as key developments. The company emphasized their strategic focus on sales growth with a 33% increase in direct-to-physician test orders quarter-over-quarter, while anticipating further growth with the expected finalization of Medicare coverage and inclusion in international clinical guidelines. Additionally, Renalytix raised $13.5 million in aggregate gross proceeds from recent financings and reported $4.7 million in cash as of March 31, excluding additional financing proceeds. The ongoing strategic review, including potential acquisition interest, was also discussed, though specifics were limited due to regulatory constraints.

Renalytix Corporate Events

Business Operations and StrategyRegulatory Filings and Compliance
UBS Reduces Holdings in Renalytix Below 5%
Neutral
Apr 29, 2025

Renalytix PLC announced that UBS Group AG’s trading book holdings in the company have fallen below 5%, exempting them from reporting obligations. This change in holdings reflects a shift in UBS’s investment strategy and could impact Renalytix’s shareholder structure, potentially influencing market perceptions and stakeholder interests.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Despite positive corporate events suggesting strategic interest and growth potential, the technical analysis and valuation remain weak, impacting the stock’s appeal.

To see Spark’s full report on GB:RENX stock, click here.

M&A TransactionsBusiness Operations and Strategy
UBS Group AG Acquires Significant Stake in Renalytix PLC
Neutral
Apr 22, 2025

Renalytix PLC has announced a significant change in its shareholder structure, with UBS Group AG acquiring a 5.043581% stake in the company. This acquisition marks a notable shift in the voting rights distribution, potentially impacting the company’s strategic decisions and signaling increased interest from major financial institutions in Renalytix’s market potential.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Despite positive corporate events suggesting strategic interest and growth potential, the technical analysis and valuation remain weak, impacting the stock’s appeal.

To see Spark’s full report on GB:RENX stock, click here.

Other
Renalytix PLC Sees Change in Major Shareholder Holdings
Neutral
Apr 17, 2025

Renalytix PLC, a company involved in the healthcare sector, has announced a significant change in its shareholder structure. UBS Group AG’s trading book holdings in Renalytix have fallen below the 5% threshold, exempting them from further reporting obligations. This shift in holdings may impact the company’s market perception and stakeholder interests, as it reflects a change in the level of institutional investment.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Although recent corporate events show promise with revenue growth and strategic investor interest, the technical analysis and valuation remain weak, impacting the stock’s appeal.

To see Spark’s full report on GB:RENX stock, click here.

M&A TransactionsBusiness Operations and Strategy
UBS Group AG Acquires Significant Stake in Renalytix
Positive
Apr 17, 2025

Renalytix PLC has announced a significant change in its shareholder structure, with UBS Group AG acquiring a 5.043581% stake in the company. This acquisition of voting rights by a major financial institution could potentially influence the company’s strategic direction and impact its market positioning, signaling confidence in Renalytix’s business model and future prospects.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Although recent corporate events show promise with revenue growth and strategic investor interest, the technical analysis and valuation remain weak, impacting the stock’s appeal.

To see Spark’s full report on GB:RENX stock, click here.

Product-Related AnnouncementsBusiness Operations and Strategy
Renalytix’s KidneyIntelX Test Shows Significant Impact on Kidney Disease Treatment
Positive
Apr 16, 2025

Renalytix has released new data at the National Kidney Foundation Spring Clinical Meeting, demonstrating the impact of its KidneyIntelX test on the prescription rates of SGLT2 inhibitors. The study shows that the test significantly increases targeted use of these inhibitors among patients at moderate or high risk of disease progression, highlighting its utility in improving patient care and outcomes. This development underscores the importance of early risk assessment in chronic kidney disease management, potentially influencing treatment protocols and enhancing Renalytix’s position in the healthcare industry.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score is low due to severe financial challenges, including declining revenues, high operating losses, and solvency issues. Although recent corporate events show promise with revenue growth and strategic investor interest, the technical analysis and valuation remain weak, impacting the stock’s appeal.

To see Spark’s full report on GB:RENX stock, click here.

Business Operations and StrategyFinancial Disclosures
Renalytix Achieves Milestone with 20% Revenue Growth in Q3
Positive
Apr 10, 2025

Renalytix has reported a 20% quarter-on-quarter revenue growth in Q3, achieving a milestone of processing over 1,000 billable tests in a quarter for the first time. This growth is supported by the onboarding of a large New York-based primary care network and increased direct-to-physician sales efforts. The company remains on track to meet its full-year expectations and plans to expand the distribution of kidneyintelX.dkd through new insurance payors, care networks, and hospital systems.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score reflects severe financial challenges, including declining revenues, high operating losses, and solvency issues. While technical indicators suggest a bearish trend, recent strategic expansions and investments by UBS Group AG could provide some optimism. However, the current valuation remains unattractive with a negative P/E ratio and no dividend yield, reinforcing cautious investor sentiment.

To see Spark’s full report on GB:RENX stock, click here.

Regulatory Filings and Compliance
UBS Reduces Holdings in Renalytix PLC Below 5% Threshold
Neutral
Apr 9, 2025

Renalytix PLC announced that UBS Group AG’s trading book holdings in the company have fallen below the 5% threshold, exempting them from further reporting obligations. This change in UBS’s holdings may impact Renalytix’s shareholder composition and could influence market perceptions of the company’s stock.

Spark’s Take on GB:RENX Stock

According to Spark, TipRanks’ AI Analyst, GB:RENX is a Underperform.

Renalytix’s overall stock score reflects severe financial challenges, including declining revenues, high operating losses, and solvency issues. While technical indicators suggest a bearish trend, recent strategic expansions and investments by UBS Group AG could provide some optimism. However, the current valuation remains unattractive with a negative P/E ratio and no dividend yield, reinforcing cautious investor sentiment.

To see Spark’s full report on GB:RENX stock, click here.

Business Operations and Strategy
UBS Reduces Holdings in Renalytix PLC Below 5%
Neutral
Mar 31, 2025

Renalytix PLC has announced that UBS Group AG’s trading book holdings in the company have fallen below 5%, exempting them from reporting obligations. This change in UBS’s holdings could impact Renalytix’s market dynamics and investor perceptions, as it reflects a shift in the investment strategy of a major financial institution.

Business Operations and StrategyRegulatory Filings and Compliance
Renalytix PLC Announces Change in Major Shareholder Holdings
Positive
Mar 25, 2025

Renalytix PLC announced a change in major holdings, with UBS Group AG, through its Investment Bank & Global Wealth Management division, acquiring a 5.043592% voting rights stake in the company. This acquisition could potentially influence the company’s strategic decisions and market positioning, reflecting UBS’s confidence in Renalytix’s business model and growth prospects.

Business Operations and StrategyRegulatory Filings and Compliance
UBS Reduces Stake in Renalytix PLC Below Reporting Threshold
Neutral
Mar 21, 2025

UBS Group AG’s trading book holdings in Renalytix PLC have fallen below the 5% threshold, making them exempt from further reporting. This change in holdings may impact Renalytix’s market perception and investor relations, as significant shifts in shareholder composition can influence company strategy and stakeholder confidence.

M&A TransactionsBusiness Operations and Strategy
UBS Group AG Acquires Major Stake in Renalytix PLC
Positive
Mar 20, 2025

Renalytix PLC has announced a change in its major holdings, with UBS Group AG acquiring a significant voting rights position of 5.043585% in the company. This acquisition may influence Renalytix’s strategic decisions and reflects UBS’s confidence in the company’s potential growth and market positioning in the healthcare diagnostics sector.

Business Operations and StrategyFinancial Disclosures
Renalytix Reports Strong Half-Year Progress and Strategic Expansion
Positive
Mar 18, 2025

Renalytix has reported strong financial and operational progress in its half-year report for FY25, with revenues of $1.3 million and a significant increase in commercial insurance reimbursed testing revenue. The company has expanded its doctor base and reduced operational costs, demonstrating a 56.5% reduction in administrative expenses. Renalytix is on track to meet or exceed its revenue growth targets, with plans to expand its kidneyintelX.dkd distribution through new insurance payors and care networks. The company’s efforts are supported by Medicare coverage, international clinical guidelines, and a growing number of pharmaceutical collaborations, positioning it well in the precision medicine industry.

Business Operations and StrategyFinancial Disclosures
Renalytix to Announce Interim Results and Host Investor Presentations
Positive
Mar 12, 2025

Renalytix announced it will release its unaudited interim results for the six months ending December 31, 2024, on March 18, 2025. The company is hosting both online and in-person investor presentations to discuss these results, inviting current shareholders and interested investors to participate. The announcement underscores the company’s commitment to transparency and engagement with stakeholders, as well as its strategic focus on expanding the deployment of kidneyintelX.dkd across the U.S. healthcare system.

Other
Renalytix PLC Sees UBS Holdings Fall Below 5% Threshold
Neutral
Feb 12, 2025

Renalytix PLC has announced a significant change in its shareholder structure, with UBS Group AG’s trading book holdings in the company falling below the 5% threshold. This change means that UBS’s holdings in Renalytix are now exempt from reporting obligations, indicating a potential shift in the investment landscape for the company.

Product-Related AnnouncementsBusiness Operations and Strategy
Renalytix’s KidneyIntelX.dkd Gains Prominence in Nephrology Advances
Positive
Feb 6, 2025

Renalytix announced that its kidneyintelX.dkd test has been featured in the Journal of the American Society of Nephrology, highlighting its significance in precision medicine for diabetic kidney disease. The test’s inclusion in the KDIGO guidelines and its role in facilitating personalized care underscores its potential to transform treatment paradigms, especially with new drug approvals like Ozempic for DKD, by providing risk-based treatment pathways that enhance patient outcomes while controlling healthcare costs.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.