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HemoGenyx Pharmaceuticals Plc (GB:HEMO)
LSE:HEMO

HemoGenyx Pharmaceuticals Plc (HEMO) AI Stock Analysis

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GB:HEMO

HemoGenyx Pharmaceuticals Plc

(LSE:HEMO)

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Neutral 43 (OpenAI - 5.2)
Rating:43Neutral
Price Target:
548.00p
▼(-3.52% Downside)
The score is held down primarily by very weak financial performance (no revenue, ongoing losses and cash burn, and increased balance sheet leverage). Technicals add modest pressure due to price sitting below key moving averages and negative MACD, while valuation offers little support given the negative P/E and no dividend yield.

HemoGenyx Pharmaceuticals Plc (HEMO) vs. iShares MSCI United Kingdom ETF (EWC)

HemoGenyx Pharmaceuticals Plc Business Overview & Revenue Model

Company DescriptionHemogenyx Pharmaceuticals Plc, a preclinical-stage biotechnology company, focuses on the discovery, development, and commercialization of therapies and treatments for blood diseases. It is involved in developing products for bone marrow/hematopoietic stem cell (BM/HSC) transplant market, including CDX bi-specific antibody targeting relapsed/refractory acute myeloid leukaemia (R/R AML), subset of acute lymphoblastic leukaemia, and myelodysplastic syndrome conditioning bone marrow transplants to substitute traditional chemotherapy and/or radiation; HEMO-CAR-T therapy, a chimeric antigen receptor T-cells to identify and destroy human AML-derived cells in vitro and in vivo; and Human Postnatal Hematopoietic Endothelial Cells, a stem cell therapy product for BM/HSC transplants. The company was founded in 2012 and is headquartered in London, the United Kingdom.
How the Company Makes Money

HemoGenyx Pharmaceuticals Plc Financial Statement Overview

Summary
Income Statement
Balance Sheet
Cash Flow
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit-631.38K-639.28K-645.68K-2.60M-283.65K-350.72K
EBITDA-6.94M-4.71M-5.73M-3.42M-2.39M-1.96M
Net Income-7.81M-5.62M-6.69M-3.98M-5.10M-2.08M
Balance Sheet
Total Assets3.10M4.21M6.11M7.09M8.52M2.66M
Cash, Cash Equivalents and Short-Term Investments226.73K159.26K1.25M2.53M6.84M1.81M
Total Debt2.20M2.62M2.95M3.42M10.15K1.63M
Total Liabilities3.65M3.36M3.32M3.85M352.84K1.79M
Stockholders Equity-500.15K897.51K2.82M3.28M8.19M890.84K
Cash Flow
Free Cash Flow-5.58M-4.13M-6.22M-3.34M-3.45M-1.97M
Operating Cash Flow-5.57M-4.12M-6.11M-2.91M-2.63M-1.80M
Investing Cash Flow235.15K-24.90K-31.94K-420.25K-938.95K-169.68K
Financing Cash Flow1.91M3.08M4.45M-110.14K8.78M3.21M

HemoGenyx Pharmaceuticals Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
73
Outperform
£42.94M7.772.94%11.92%-33.76%
56
Neutral
£34.92M-3.96-204.29%3.31%21.91%
52
Neutral
£26.97M-6.96-213.66%39.88%81.33%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
£29.28M-3.77-46.84%
46
Neutral
£37.80M-8.07-259.88%
43
Neutral
£36.85M-2.82-609.30%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:HEMO
HemoGenyx Pharmaceuticals Plc
621.00
228.50
58.22%
GB:IMM
ImmuPharma
7.30
3.75
105.63%
GB:HVO
Open Orphan Plc
6.20
-11.70
-65.36%
GB:POLB
Poolbeg Pharma Ltd.
4.35
-0.80
-15.53%
GB:AREC
Arecor Therapeutics PLC
86.00
27.50
47.01%
GB:APTA
Aptamer Group Plc
0.98
0.65
195.45%

HemoGenyx Pharmaceuticals Plc Corporate Events

Delistings and Listing ChangesPrivate Placements and FinancingRegulatory Filings and Compliance
Hemogenyx Sets Early January Date for Admission of New Shares
Neutral
Dec 22, 2025

Hemogenyx Pharmaceuticals has confirmed that the UK Financial Conduct Authority has scheduled an admission hearing for its new ordinary shares on 5 January 2026, with trading in the new shares expected to commence at around 8:00 a.m. on 6 January 2026. The timing update indicates the capital-related process is progressing as planned, with all other terms from the company’s 18 December 2025 announcement remaining unchanged, providing investors and other stakeholders with clarity on the anticipated schedule for the shares’ admission to trading.

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Hemogenyx Pharmaceuticals Announces Equity Issuance and Operational Updates
Positive
Dec 18, 2025

Hemogenyx Pharmaceuticals plc has issued 123,377 new ordinary shares following warrant exercises, restricted stock unit vesting, and obligations under a Deed of Variation. This issuance, raising £190,000 and leading to adjustments in total issued shares and voting rights, reflects the company’s ongoing efforts to fund operational developments and ensure alignment with regulatory requirements, which may strengthen its market positioning and reassure stakeholders.

Delistings and Listing ChangesPrivate Placements and Financing
Hemogenyx Pharmaceuticals Publishes Prospectus for New Share Admission
Neutral
Nov 19, 2025

Hemogenyx Pharmaceuticals has announced the publication of a Prospectus related to the admission of new ordinary shares to the London Stock Exchange. This move involves the conversion of convertible loan notes and the exercise of warrants, with trading expected to commence on 24 November 2025. This development is significant for Hemogenyx as it enhances their market presence and potentially impacts their financial standing by increasing the number of shares available for trading.

Business Operations and StrategyProduct-Related Announcements
Hemogenyx Pharmaceuticals Advances CAR-T Therapy Trial with DSMB Approval
Positive
Oct 29, 2025

Hemogenyx Pharmaceuticals announced that the Data Safety Monitoring Board has approved the continuation of its Phase I clinical trial for HG-CT-1, a CAR-T therapy for acute myeloid leukemia, allowing dose escalation and the start of pediatric recruitment. This milestone signifies a de-risking step in the therapy’s development, potentially enhancing its efficacy and paving the way for broader clinical validation, which could positively impact the company’s market position and investor interest.

Business Operations and StrategyProduct-Related Announcements
Hemogenyx Pharmaceuticals Expands Clinical Trial to Include Pediatric Patients
Positive
Oct 6, 2025

Hemogenyx Pharmaceuticals announced that the Institutional Review Board at MD Anderson Cancer Center has approved an amendment to their Phase I trial of HG-CT-1, a CAR-T cell therapy for relapsed or refractory acute myeloid leukemia, to include pediatric patients. This expansion marks a significant milestone, broadening the potential patient population and demonstrating the company’s commitment to advancing treatment options in the pediatric setting, which may enhance their market positioning and support long-term growth.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 04, 2026