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HemoGenyx Pharmaceuticals Plc (GB:HEMO)
LSE:HEMO
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HemoGenyx Pharmaceuticals Plc (HEMO) AI Stock Analysis

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GB:HEMO

HemoGenyx Pharmaceuticals Plc

(LSE:HEMO)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
662.00 p
▲(16.55% Upside)
Action:Reiterated
Date:05/10/26
Overall score is driven primarily by weak financial performance (no revenue, widening losses, and ongoing cash burn with a leveraged and shrinking equity base). Technicals also weigh on the score as price sits below key moving averages with negative MACD, despite oversold RSI/Stochastic. Valuation provides limited support because the company is loss-making (negative P/E) and no dividend yield is available.
Positive Factors
Debt reduction
A multi-year reduction in total debt meaningfully lowers financing pressure for a loss-making biotech. Reduced debt cuts future interest/service needs and modestly extends runway, improving the company's ability to fund R&D or negotiate partnerships without immediate refinancing risk.
Negative Factors
Pre-revenue profile
Absence of any revenue forces reliance on external capital and milestone/licensing events to sustain operations. For a development-stage biotech this raises long-term dilution risk, restricts reinvestment capacity, and creates uncertainty around the timing and certainty of commercialization.
Read all positive and negative factors
Positive Factors
Negative Factors
Debt reduction
A multi-year reduction in total debt meaningfully lowers financing pressure for a loss-making biotech. Reduced debt cuts future interest/service needs and modestly extends runway, improving the company's ability to fund R&D or negotiate partnerships without immediate refinancing risk.
Read all positive factors

HemoGenyx Pharmaceuticals Plc (HEMO) vs. iShares MSCI United Kingdom ETF (EWC)

HemoGenyx Pharmaceuticals Plc Business Overview & Revenue Model

Company Description
Hemogenyx Pharmaceuticals Plc, a preclinical-stage biotechnology company, focuses on the discovery, development, and commercialization of therapies and treatments for blood diseases. It is involved in developing products for bone marrow/hematopoie...
How the Company Makes Money
Publicly available, specific details describing HemoGenyx Pharmaceuticals Plc’s current revenue model, recurring revenue streams, and monetization mechanisms (e.g., product sales, licensing/royalties, milestone payments, contract services, or mate...

HemoGenyx Pharmaceuticals Plc Financial Statement Overview

Summary
Pre-revenue profile with no revenue reported and persistent, volatile losses (net loss widening to ~-9.8m in 2025 from ~-5.6m in 2024). Cash flow remains a key weakness with ongoing negative operating and free cash flow despite a modest improvement in 2025 burn versus 2024. Balance sheet risk is elevated as debt exceeds equity and equity has shrunk materially, though debt reduction from 2023–2025 is a partial positive.
Income Statement
8
Very Negative
Balance Sheet
26
Negative
Cash Flow
12
Very Negative
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-588.75K-639.28K-645.68K-2.60M-283.65K
EBITDA-4.07M-4.71M-5.73M-3.42M-2.39M
Net Income-9.76M-5.62M-6.69M-3.98M-5.10M
Balance Sheet
Total Assets4.18M4.21M6.11M7.09M8.52M
Cash, Cash Equivalents and Short-Term Investments1.59M159.26K1.25M2.53M6.84M
Total Debt2.00M2.62M2.95M3.42M10.15K
Total Liabilities3.03M3.36M3.32M3.85M352.84K
Stockholders Equity1.20M897.51K2.82M3.28M8.19M
Cash Flow
Free Cash Flow-3.45M-4.13M-6.22M-3.34M-3.45M
Operating Cash Flow-3.45M-4.12M-6.11M-2.91M-2.63M
Investing Cash Flow-6.80K-24.90K-31.94K-420.25K-938.95K
Financing Cash Flow4.89M3.08M4.45M-110.14K8.78M

HemoGenyx Pharmaceuticals Plc Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
55
Neutral
£33.84M-4.23-55.47%19.83%
53
Neutral
£51.63M-1.83-14.65%2.94%-25.43%-155.41%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
46
Neutral
£26.83M-3.00-6634.51%
46
Neutral
£24.92M45.77-197.54%3.31%21.91%
42
Neutral
£45.83M-1.82-3931.14%-28.29%
40
Underperform
£19.87M-6.19-213.66%13.42%65.63%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
GB:HEMO
HemoGenyx Pharmaceuticals Plc
677.50
501.00
283.85%
GB:IMM
ImmuPharma
4.52
1.65
57.77%
GB:HVO
Open Orphan Plc
7.95
-9.25
-53.78%
GB:POLB
Poolbeg Pharma Ltd.
4.80
2.30
92.00%
GB:AREC
Arecor Therapeutics PLC
66.00
24.00
57.14%
GB:APTA
Aptamer Group Plc
0.58
0.20
55.41%

HemoGenyx Pharmaceuticals Plc Corporate Events

Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingRegulatory Filings and Compliance
Hemogenyx advances lead CAR-T trial and secures funding to complete Phase 1
Positive
Apr 30, 2026
Hemogenyx Pharmaceuticals reported its final audited results for 2025, highlighting significant clinical and operational progress as it advances its lead CAR-T therapy, HG-CT-1, for relapsed or refractory acute myeloid leukaemia. The company has t...
Business Operations and StrategyPrivate Placements and Financing
Hemogenyx Raises £3m to Accelerate HG-CT-1 Trials and Early Commercialisation
Positive
Apr 28, 2026
Hemogenyx Pharmaceuticals has raised £3 million from a small group of institutional investors via a direct subscription of 374,532 new shares to accelerate clinical development of its CAR-T therapy HG-CT-1. The capital will primarily fund Pha...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Hemogenyx Files Annual FDA IND Report as AML CAR‑T Trial Shows Early Promise
Positive
Apr 14, 2026
Hemogenyx Pharmaceuticals has filed its annual Investigational New Drug report with the U.S. Food and Drug Administration for HG‑CT‑1, its proprietary CAR‑T cell therapy for relapsed or refractory acute myeloid leukemia, summaris...
Business Operations and StrategyProduct-Related AnnouncementsRegulatory Filings and Compliance
Hemogenyx Advances HG-CT-1 CAR-T Program With Manufacturing Transfer and Trial Expansion
Positive
Mar 31, 2026
Hemogenyx Pharmaceuticals has completed the technology transfer of manufacturing for its HG-CT-1 CAR-T cell therapy for relapsed or refractory acute myeloid leukemia to contract developer and manufacturer Made Scientific. A comparability data pack...
Business Operations and StrategyRegulatory Filings and Compliance
Hemogenyx Pharmaceuticals Updates Share Capital and Voting Rights Structure
Neutral
Feb 27, 2026
Hemogenyx Pharmaceuticals plc, a clinical-stage biopharmaceutical group listed on the LSE and focused on therapies for blood and autoimmune diseases, operates from London with U.S. subsidiaries in New York City supporting its pipeline of product c...
Private Placements and FinancingRegulatory Filings and Compliance
Hemogenyx Raises £118,632 Through Warrant Exercise and Expands Share Capital
Positive
Feb 23, 2026
Hemogenyx Pharmaceuticals has received notices to exercise warrants over 50,841 new ordinary shares at prices between 180p and 350p, raising £118,632 in fresh capital. The new shares will be admitted to the FCA’s Official List and to tr...
Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and Compliance
Hemogenyx Raises £2.5m to Advance CAR-T Trials in Adult and Pediatric AML
Positive
Feb 10, 2026
Hemogenyx Pharmaceuticals has raised £2.5 million from a consortium of private investors via a direct subscription for 333,333 new shares at £7.50 each, alongside three-year warrants exercisable at £9, increasing its issued share ca...
Business Operations and StrategyPrivate Placements and Financing
Hemogenyx Raises £2.5m to Advance AML CAR-T Trials and Reduce Costs
Positive
Feb 10, 2026
Hemogenyx Pharmaceuticals has raised £2.5 million through a direct subscription of 313,333 new shares at £7.50 each from a consortium of private investors, accompanied by three-year warrants exercisable at £9. The funds will primari...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: May 10, 2026