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Dynavax Technologies Corp. (DVAX)
NASDAQ:DVAX

Dynavax (DVAX) AI Stock Analysis

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Dynavax

(NASDAQ:DVAX)

57Neutral
Dynavax's overall score reflects a mix of strengths and challenges. The company demonstrates strong revenue growth and cash flow management, but profitability issues and bearish technical indicators weigh down the score. The high P/E ratio suggests overvaluation, while the positive outlook from the earnings call provides some optimism. Overall, the stock presents potential growth opportunities but comes with significant risks.
Positive Factors
Financial Performance
Heplisav-B sales grew 39% YoY, with total U.S. market share increasing to approximately 44% at the end of 2024.
Market Opportunity
Analyst sees continued market share gains for Heplisav as a driver for company growth.
Share Repurchase
Dynavax announced a $200M share repurchase program, with a $100M accelerated share repurchase transaction already completed.
Negative Factors
Sales Decline
Management had anticipated seasonality to reduce Q4 sales by approx. 15% compared to Q3, resulting in a -10% Q/Q decline.

Dynavax (DVAX) vs. S&P 500 (SPY)

Dynavax Business Overview & Revenue Model

Company DescriptionDynavax Technologies Corporation, a biopharmaceutical company, focuses on developing and commercializing novel vaccines in the United States. The company markets HEPLISAV-B, a hepatitis B vaccine for prevention of infection caused by all known subtypes of hepatitis B virus in age 18 years and older in the United States and Europe. It also manufactures and sells CpG 1018, the adjuvant used in HEPLISAV-B. Dynavax Technologies Corporation has a collaboration agreement with Valneva Scotland Limited; agreement with Serum Institute of India Pvt. Ltd.; and sublicense agreement with Merck, Sharp & Dohme Corp. The company was formerly known as Double Helix Corporation and changed its name to Dynavax Technologies Corporation in September 1996. Dynavax Technologies Corporation was incorporated in 1996 and is headquartered in Emeryville, California.
How the Company Makes MoneyDynavax makes money primarily through the sale and distribution of HEPLISAV-B, its FDA-approved hepatitis B vaccine for adults. The company generates revenue by marketing this vaccine to healthcare providers, clinics, and government entities. Key revenue streams include product sales, which are driven by demand in both the private and public healthcare sectors. Additionally, Dynavax may receive revenue from partnerships and collaborations with other pharmaceutical companies or government agencies for the development of new vaccines or immunotherapy solutions. These collaborations can provide upfront payments, milestone payments, and royalties on future sales, contributing to the company's earnings.

Dynavax Financial Statement Overview

Summary
Dynavax has shown positive revenue growth and a healthy gross margin, but profitability remains a concern with negative EBIT and EBITDA margins. The balance sheet is stable with a strong equity position but carries some leverage risk. Cash flow performance is solid, with efficient cash generation and management, supporting the company's operations despite ongoing profitability challenges.
Income Statement
48
Neutral
Dynavax shows a growth in revenue from the previous year, with a revenue growth rate of 19.34% in the latest period. However, the company has struggled with profitability, as seen in the negative EBIT and EBITDA margins, indicating operational challenges. The gross profit margin is healthy at 100% due to the total revenue equating to gross profit, but net profit margin is modest at 9.85% due to net income being relatively low compared to total revenue.
Balance Sheet
62
Positive
The balance sheet reflects a strong equity base with an equity ratio of 60.50%, indicating financial stability. However, the debt-to-equity ratio is relatively high at 0.42, suggesting some leverage risk. Return on equity is low at 4.58%, suggesting that the company is not generating substantial returns on shareholders' equity.
Cash Flow
75
Positive
Dynavax shows strong operating cash flow relative to net income, with a robust free cash flow growth rate of 6.90%. The operating cash flow to net income ratio is 2.43, reflecting efficient cash generation. The company's free cash flow to net income ratio is also strong at 2.20, indicating effective cash management.
Breakdown
Dec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income StatementTotal Revenue
277.25M232.28M722.68M439.44M46.55M
Gross Profit
277.25M182.12M460.53M265.87M32.64M
EBIT
-4.12M-37.03M283.52M134.49M-75.22M
EBITDA
45.70M9.67M307.70M95.71M-46.84M
Net Income Common Stockholders
27.31M-6.39M293.16M76.71M-91.78M
Balance SheetCash, Cash Equivalents and Short-Term Investments
713.83M742.30M624.39M545.95M165.04M
Total Assets
986.26M997.10M985.85M1.04B353.27M
Total Debt
250.24M256.91M258.01M257.38M217.85M
Net Debt
154.36M106.64M56.01M-178.81M185.77M
Total Liabilities
389.46M375.02M404.84M816.87M294.58M
Stockholders Equity
596.80M622.07M581.01M222.37M58.69M
Cash FlowFree Cash Flow
60.16M96.46M55.58M326.05M-103.32M
Operating Cash Flow
66.51M100.56M62.72M335.53M-92.25M
Investing Cash Flow
-18.04M-153.93M-316.00M14.22M-26.53M
Financing Cash Flow
-102.02M1.39M19.52M55.78M109.50M

Dynavax Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.82
Price Trends
50DMA
12.86
Negative
100DMA
12.84
Negative
200DMA
12.07
Negative
Market Momentum
MACD
-0.70
Positive
RSI
34.11
Neutral
STOCH
51.31
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DVAX, the sentiment is Negative. The current price of 10.82 is below the 20-day moving average (MA) of 11.68, below the 50-day MA of 12.86, and below the 200-day MA of 12.07, indicating a bearish trend. The MACD of -0.70 indicates Positive momentum. The RSI at 34.11 is Neutral, neither overbought nor oversold. The STOCH value of 51.31 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for DVAX.

Dynavax Risk Analysis

Dynavax disclosed 50 risk factors in its most recent earnings report. Dynavax reported the most risks in the “Finance & Corporate” category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Dynavax Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
70
Outperform
$1.15B7.9023.26%13.59%15.72%
65
Neutral
$1.19B-12.08%3.85%-339.15%
65
Neutral
$1.80B24.447.55%8.94%5171.26%
65
Neutral
$1.51B-4.86%26.20%-219.22%
57
Neutral
$1.32B61.934.48%19.36%
51
Neutral
$5.32B3.41-40.36%2.89%17.93%2.52%
EVEVO
50
Neutral
$1.49B-19.05%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DVAX
Dynavax
10.82
-0.52
-4.59%
PCRX
Pacira Pharmaceuticals
25.72
-0.33
-1.27%
SUPN
Supernus Pharmaceuticals
32.22
1.62
5.29%
ANIP
ANI Pharmaceuticals
69.82
4.32
6.60%
AMPH
Amphastar Pharmaceuticals
24.19
-17.83
-42.43%
EVO
Evotec AG
4.22
-0.98
-18.85%

Dynavax Earnings Call Summary

Earnings Call Date:Feb 20, 2025
(Q4-2024)
|
% Change Since: -18.83%|
Next Earnings Date:May 06, 2025
Earnings Call Sentiment Positive
The earnings call conveyed a positive outlook for Dynavax, highlighted by record revenue growth, market leadership in hepatitis B vaccines, and promising clinical advancements. However, challenges remain in the approval of the hemodialysis vaccine and increasing R&D expenses.
Q4-2024 Updates
Positive Updates
Record HEPLISAV-B Revenue Growth
HEPLISAV-B achieved record net revenues of $71 million for Q4 and $268 million for the full year 2024, reflecting a 39% and 26% increase year-over-year, respectively.
Market Share Leadership in Hepatitis B Vaccine
HEPLISAV-B increased its market share to 44% by the end of 2024, becoming the market leader in the U.S. hepatitis B adult vaccine market.
Positive Market Dynamics for HEPLISAV-B
Medicare policy changes and the inclusion of hepatitis B vaccination in HEDIS measures are expected to boost market share and revenue growth for HEPLISAV-B in 2025.
Strong Financial Performance and Guidance
Dynavax achieved profitability with a net income of $27 million for 2024. The company also set guidance for 2025 with expected HEPLISAV-B net product revenue between $305 million to $325 million.
Clinical Pipeline Advancements
The shingles vaccine program, Z-1018, showed promising Phase I results with favorable tolerability compared to Shingrix and is advancing to a Phase I/II study.
Negative Updates
Challenges in Hemodialysis Vaccine Approval
The FDA issued a complete response letter for the HEPLISAV-B vaccine regimen for adults on hemodialysis, leading to delays in approval.
Increased R&D Expenses
R&D expenses rose by 32% in Q4 year-over-year and are expected to increase by high teens percent in 2025 as Dynavax progresses its clinical pipeline.
Company Guidance
During Dynavax Technologies' fourth quarter and full year 2024 financial results conference call, the company provided guidance for 2025, expecting HEPLISAV-B net product sales to reach between $305 million to $325 million, driven by an expanding adult hepatitis B vaccine market and anticipated market share gains. HEPLISAV-B's market share reached 44% by the end of 2024, with net revenues totaling $71 million for the fourth quarter and $268 million for the full year. The company foresees the adult hepatitis B vaccine market expanding to over $900 million by 2030, with HEPLISAV-B capturing at least 60% market share. For 2025, Dynavax projects adjusted EBITDA, excluding stock-based compensation, to be at least $75 million, demonstrating growth at more than twice the rate of product revenue. The company also plans to advance its shingles vaccine program, with a Phase I/II study readout expected in the third quarter of 2025, aiming to establish proof of concept and prepare for a Phase III global launch.

Dynavax Corporate Events

Product-Related AnnouncementsExecutive/Board Changes
Dynavax Appoints New Principal Accounting Officer
Neutral
Feb 14, 2025

On February 10, 2025, Dynavax Technologies Corporation entered into a new Supply Agreement with West Pharmaceutical Services, Inc. for the manufacture and supply of syringe stoppers for its HEPLISAV-B® vaccine, replacing a prior agreement from 2016. This new agreement, effective for four years with possible extensions, outlines volume-based pricing subject to changes according to a specified price index and includes provisions for termination due to breach or insolvency. Additionally, on February 13, 2025, the company’s Board of Directors appointed Kelly MacDonald as the principal accounting officer, expanding her responsibilities as the Chief Financial Officer.

Executive/Board Changes
Dynavax Announces Leadership Transition Following Resignation
Neutral
Feb 7, 2025

On February 3, 2025, Justin Burgess announced his resignation from Dynavax Technologies Corporation, where he served as the principal accounting officer, effective on or around March 3, 2025. The company plans to appoint Kelly MacDonald, the current Chief Financial Officer, as the new principal accounting officer without changing her compensation, indicating a seamless transition in leadership roles within the company.

Executive/Board Changes
Dynavax Announces New Board Appointments and Adjustments
Neutral
Jan 29, 2025

Dynavax Technologies Corporation has appointed two new directors, Lauren Silvernail and Emilio Emini, Ph.D., effective February 3, 2025. Lauren Silvernail will serve as a Class I Director until the 2025 Annual Meeting and chair the Audit Committee, while Emilio Emini will serve as a Class III Director until the 2027 Annual Meeting. Both will receive stock options and restricted stock units as part of their compensation, with Silvernail also receiving additional compensation for her role in the Audit Committee. The appointments follow the retirement and resignation of directors Peggy V. Phillips and Julie Eastland, and the Board’s decision to adjust the number of directors accordingly.

Glossary
OutperformA stock rated as "Outperform" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock is likely to deliver higher returns compared to the average returns of other stocks in the same sector or market index. Investors might consider this stock a good buying opportunity.
NeutralA stock rated as "Neutral" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly attractive nor unattractive for investment. Investors may consider holding onto the stock, as it is not expected to either significantly outperform or underperform the market.
UnderperformA stock rated as "Underperform" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests that the stock may deliver lower returns compared to the average returns of other stocks in the same sector or market index. Investors might consider selling the stock or avoiding it as an investment.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.