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Alpha Tau Medical Ltd (DRTS)
NASDAQ:DRTS
US Market

Alpha Tau Medical Ltd (DRTS) AI Stock Analysis

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DRTS

Alpha Tau Medical Ltd

(NASDAQ:DRTS)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$6.50
▲(11.30% Upside)
Overall score is held down primarily by very weak fundamentals (no revenue, ongoing losses, and persistent cash burn), with only partial support from an improved balance sheet. Technicals are a near-term positive with strong trend strength, but overbought momentum indicators add downside risk. Valuation remains unattractive/unclear due to negative earnings and no dividend yield.
Positive Factors
Improved balance sheet / positive equity
Positive equity and moderate leverage materially improve solvency versus prior years, providing a steadier capital base to fund pivotal trials and near-term commercial setup. This reduces near-term bankruptcy risk and gives management time to advance regulatory milestones before needing dilutive financing.
Regulatory progress — FDA PMA modular submission
Submitting a modular PMA is a structural regulatory milestone that can streamline staged review of non-clinical and clinical modules. If subsequent modules and data support approval, this materially shortens formal review complexity and strengthens the pathway to U.S. market access for a defined indication.
Robust clinical data in pancreatic study
Strong disease control and acceptable safety in a hard-to-treat indication bolster the therapy's clinical value proposition and support combinations with systemic therapies. Durable efficacy signals in pancreatic cancer can underpin regulatory filings, payer interest, and long-term commercial demand if replicated in larger trials.
Negative Factors
No revenue; persistent net losses
Zero commercial revenue and recurring multi-year losses indicate the company remains pre-revenue and dependent on trial success to generate sales. This structural lack of operating income means long-term viability hinges on successful approvals and commercialization, heightening dilution and execution risk for investors.
Sustained negative operating and free cash flow
Consistent negative OCF and FCF reflect ongoing cash burn to support R&D and trials. Over months ahead, the company will likely require additional financing to sustain operations, which can delay programs or dilute shareholders and constrains the firm's ability to invest in commercialization infrastructure independently.
Eroding assets and rising debt; negative returns
Falling asset base alongside higher debt reduces financial flexibility and the cushion available for setbacks. Persistent negative returns indicate the company is not yet extracting economic value from investments, making it more vulnerable to clinical or regulatory delays that would force additional costly financing.

Alpha Tau Medical Ltd (DRTS) vs. SPDR S&P 500 ETF (SPY)

Alpha Tau Medical Ltd Business Overview & Revenue Model

Company DescriptionAlpha Tau Medical Ltd., a clinical-stage oncology therapeutics company, engages in research, development, and commercialization of diffusing alpha-emitters radiation therapy (Alpha DaRT) for the treatment of solid cancer In Israel and the United States. Its Alpha-DaRT technology used in clinical trials for skin, oral, pancreatic, and breast cancers; and preclinical studies for hepatic cell carcinoma, glioblastoma multiforme, lung cancer, and others. The company was incorporated in 2015 and is headquartered in Jerusalem, Israel.
How the Company Makes MoneyAlpha Tau Medical Ltd generates revenue primarily through the commercialization of its proprietary Alpha DaRT technology. The company's revenue model includes direct sales of its products to healthcare providers and hospitals, as well as licensing agreements that allow other medical institutions and companies to utilize its technology. Additionally, Alpha Tau Medical may engage in strategic partnerships and collaborations with pharmaceutical companies and research institutions to further develop and expand the applications of its technology, potentially resulting in additional revenue streams through milestone payments and royalties. The company's finances are also supported by investments and funding from venture capital and other investors interested in innovative cancer treatment solutions.

Alpha Tau Medical Ltd Financial Statement Overview

Summary
Financial profile is very weak: revenue is $0 across 2019–2024 with persistent sizable losses (2024 net loss about $31.8M) and ongoing operating/FCF burn (2024 operating cash flow about -$19.8M; free cash flow about -$22.0M). The main offset is an improved balance sheet versus 2020–2021 with positive 2024 equity (~$62.7M) and moderate leverage (debt-to-equity ~0.20).
Income Statement
14
Very Negative
The income statement remains very weak: revenue is consistently $0 across 2019–2024, while gross profit is negative each year, indicating ongoing operating costs without commercial sales. Losses are persistent and sizable (net loss of about $31.8M in 2024 vs. ~$29.2M in 2023), and operating profit is also deeply negative in most years (2024 EBIT about -$36.0M). A notable inconsistency appears in 2023 where operating profit is shown as strongly positive despite negative EBITDA and net income, which reduces confidence in trend quality; regardless, the business is still meaningfully unprofitable.
Balance Sheet
58
Neutral
The balance sheet is mixed but improved versus earlier years. Equity is positive and substantial in 2024 (~$62.7M) after being negative in 2020–2021, suggesting recapitalization and better solvency today. Leverage is currently moderate (debt-to-equity ~0.20 in 2024), though debt has increased from 2022 (~$5.2M) to 2024 (~$12.5M) while assets have declined from 2022 (~$120.1M) to 2024 (~$86.2M). Returns remain poor (negative return on equity in 2022–2024), reflecting ongoing losses despite the healthier capital structure.
Cash Flow
22
Negative
Cash flow is a key pressure point: operating cash flow is consistently negative (about -$19.8M in 2024, -$18.0M in 2023), and free cash flow is also consistently negative (about -$22.0M in 2024). Free cash flow burn improved sharply from 2022 to 2023, but worsened again in 2024, signaling an uneven burn trajectory. While free cash flow is less negative than net income in recent years (free cash flow to net income above 1.0), the company still relies on external funding to sustain operations given the ongoing cash outflows.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.000.000.000.000.000.00
Gross Profit0.00-1.10M-1.07M-979.00K-776.00K-86.00K
EBITDA-34.34M-30.30M-28.03M-32.74M-13.21M-9.16M
Net Income-39.97M-31.75M-29.16M-33.76M-27.27M-8.88M
Balance Sheet
Total Assets104.69M86.20M107.39M120.15M42.22M52.99M
Cash, Cash Equivalents and Short-Term Investments72.21M59.60M81.79M104.53M31.32M46.02M
Total Debt13.50M12.54M13.28M5.19M53.96M53.96M
Total Liabilities27.11M23.54M22.91M14.49M76.99M61.42M
Stockholders Equity77.58M62.67M84.47M105.66M-34.78M-8.43M
Cash Flow
Free Cash Flow0.00-22.02M-24.36M-24.78M-14.74M-11.02M
Operating Cash Flow0.00-19.78M-17.96M-23.88M-11.81M-7.25M
Investing Cash Flow0.0020.77M18.68M-89.94M19.27M-7.82M
Financing Cash Flow0.0025.00K5.30M96.91M111.00K29.32M

Alpha Tau Medical Ltd Technical Analysis

Technical Analysis Sentiment
Positive
Last Price5.84
Price Trends
50DMA
5.57
Positive
100DMA
4.79
Positive
200DMA
3.93
Positive
Market Momentum
MACD
0.50
Positive
RSI
63.59
Neutral
STOCH
59.75
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DRTS, the sentiment is Positive. The current price of 5.84 is below the 20-day moving average (MA) of 7.03, above the 50-day MA of 5.57, and above the 200-day MA of 3.93, indicating a bullish trend. The MACD of 0.50 indicates Positive momentum. The RSI at 63.59 is Neutral, neither overbought nor oversold. The STOCH value of 59.75 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DRTS.

Alpha Tau Medical Ltd Risk Analysis

Alpha Tau Medical Ltd disclosed 85 risk factors in its most recent earnings report. Alpha Tau Medical Ltd reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Alpha Tau Medical Ltd Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$1.33B-13.62-107.79%-52.08%-69.35%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$648.01M-14.57-54.38%-22.82%
48
Neutral
$420.23M-12.34-43.71%80.95%
46
Neutral
$530.62M-2.69-80.69%4.97%
45
Neutral
$280.74M-1.70-78.24%-67.41%
42
Neutral
$365.14M-2.98-64.26%-11.41%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DRTS
Alpha Tau Medical Ltd
7.60
4.28
128.92%
LRMR
Larimar Therapeutics
3.28
-0.54
-14.14%
CAPR
Capricor Therapeutics
24.50
10.17
70.97%
BNTC
Benitec Biopharma
12.41
0.66
5.62%
AURA
Aura Biosciences Inc
5.75
-2.46
-29.96%
LXEO
Lexeo Therapeutics, Inc.
7.27
1.46
25.13%

Alpha Tau Medical Ltd Corporate Events

Alpha Tau Outlines Aggressive 2026 Clinical Schedule and Manufacturing Ramp for Alpha DaRT Cancer Therapy
Jan 29, 2026

On January 29, 2026, Alpha Tau Medical issued a shareholder letter outlining an intensifying clinical and pre-commercial agenda for 2026, highlighted by five concurrent U.S. trials of its Alpha DaRT therapy in skin, pancreatic, brain and prostate cancers, additional studies in Europe and Israel, and preparations for a large basket trial in the UK. The company expects to complete patient recruitment in its IMPACT pancreatic cancer trial by the end of the first quarter of 2026 with initial data anticipated by year-end, is targeting first results from its U.S. glioblastoma study around the end of 2026, and is awaiting a near-term regulatory decision in Japan on Alpha DaRT for recurrent head and neck cancer that could mark its first commercial approval outside Israel. Alongside ongoing data generation from its pivotal ReSTART skin cancer trial and planned exploration of Alpha DaRT in combination with checkpoint inhibitors for advanced head and neck cancer, Alpha Tau is ramping U.S. manufacturing capacity, advancing a modular PMA submission to the FDA, and building organizational and production infrastructure in the U.S. and Israel, signaling that it is positioning itself for potential commercialization and broader adoption of its platform if upcoming clinical and regulatory milestones are favorable.

The most recent analyst rating on (DRTS) stock is a Hold with a $7.50 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical Unveils Strong Pancreatic Cancer Alpha DaRT Data Ahead of ASCO GI 2026
Jan 6, 2026

On January 6, 2026, Alpha Tau Medical reported final results from its first-in-human pancreatic ductal adenocarcinoma study in Montreal, showing an 81% disease control rate across 32 patients treated with its Alpha DaRT therapy, rising to 87% when excluding the first two low-dose feasibility patients, along with a 22–23% objective response rate and a favorable safety profile. Complementary data from 23 patients demonstrated preservation of key immune and inflammatory markers one month after treatment, including stable neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios and a marked reduction in IL-6 levels, suggesting an immune-preserving, less inflammatory radiation profile that could support combination with systemic therapies such as chemotherapy or immunotherapy; these findings reinforce Alpha Tau’s strategic focus on pancreatic cancer, underpin ongoing U.S. and European trials, and may strengthen the company’s positioning as it seeks future regulatory approval for Alpha DaRT in this high-need indication.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Files First FDA PMA Module for Alpha DaRT Skin Cancer Therapy
Jan 5, 2026

On January 5, 2026, Alpha Tau Medical announced it has submitted the first module of its pre-market approval application to the U.S. Food and Drug Administration for Alpha DaRT in the treatment of recurrent cutaneous squamous cell carcinoma in patients who are not candidates for surgery or standard radiation and lack curative systemic options. The FDA has allowed the company to use a modular PMA approach, enabling staged review of non-clinical and other data, and the initial module focuses on comprehensive non-clinical documentation; this step, taken in parallel with the ongoing multi-center ReSTART pivotal study that is expected to complete patient recruitment in the first quarter of 2026, marks a key regulatory milestone that could help streamline U.S. review and potentially strengthen Alpha Tau’s position in the skin cancer treatment market if future modules and clinical results support approval.

The most recent analyst rating on (DRTS) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical to Present Corporate Update at J.P. Morgan 2026 Healthcare Conference
Dec 18, 2025

On December 18, 2025, Alpha Tau Medical Ltd. announced that CEO Uzi Sofer and CFO Raphi Levy will deliver a corporate overview and update at the J.P. Morgan 2026 Healthcare Conference in San Francisco on January 15, 2026, and will hold one-on-one meetings with institutional investors during the event. The presentation is expected to highlight the company’s recent achievements and outline upcoming data milestones for its Alpha DaRT solid-tumor therapy, signaling an effort to raise Alpha Tau’s visibility with global healthcare investors and potentially strengthen its position within the oncology therapeutics space as it advances toward further clinical and commercial development.

The most recent analyst rating on (DRTS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Treats First U.S. Patient with Alpha DaRT for Glioblastoma
Dec 9, 2025

On December 9, 2025, Alpha Tau Medical Ltd. announced the successful treatment of the first patient in its U.S. trial for recurrent glioblastoma using its Alpha DaRT technology at The Ohio State University. This pilot study is part of Alpha Tau’s strategy to address high unmet needs in cancer treatment, supported by FDA’s Breakthrough Device Designation, and marks a significant milestone in neuro-oncology by offering a novel therapeutic approach for a highly resistant cancer.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical to Present Pancreatic Cancer Research at 2026 ASCO Symposium
Dec 4, 2025

On December 4, 2025, Alpha Tau Medical Ltd. announced the acceptance of two abstracts related to its Alpha DaRT technology for presentation at the 2026 ASCO Gastrointestinal Cancers Symposium. These abstracts, focusing on pancreatic cancer, highlight the company’s ongoing clinical trials, including a multi-center study in the U.S. that began in September 2025. This development underscores Alpha Tau’s commitment to addressing high unmet needs in cancer treatment, particularly for pancreatic cancer patients who often face limited treatment options.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical Receives FDA Approval for Prostate Cancer Trial
Dec 2, 2025

On December 2, 2025, Alpha Tau Medical Ltd. announced that it received FDA approval to initiate a pilot study for treating patients with locally recurrent prostate cancer using its Alpha DaRT technology. This marks the company’s fifth active U.S. IDE, expanding its reach in the U.S. market. The trial will enroll up to 12 U.S. patients and aims to evaluate the safety and efficacy of Alpha DaRT as a local salvage therapy, offering an alternative to current treatments for recurrent prostate cancer. This development could significantly impact Alpha Tau’s operations and industry positioning, as it addresses a critical need for new treatments in the prostate cancer segment.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical Reports Q3 2025 Results and Advances in Cancer Therapy
Nov 20, 2025

On November 20, 2025, Alpha Tau Medical Ltd. announced its third quarter 2025 financial results and provided a corporate update. The company highlighted significant progress, including the commencement of Alpha DaRT pancreatic cancer treatments in a U.S. multi-center pilot study and the receipt of a radioactive material license for its New Hampshire facility, positioning it for commercial readiness. Alpha Tau also reported a cash balance of $75.9 million, supporting ongoing clinical advancements and commercial preparations. The company aims to achieve several milestones in the coming months, such as completing patient recruitment in the U.S. ReSTART trial and receiving a response from Japan’s PMDA regarding marketing authorization for treating recurrent head and neck cancer.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 15, 2026