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Alpha Tau Medical Ltd (DRTS)
NASDAQ:DRTS
US Market

Alpha Tau Medical Ltd (DRTS) AI Stock Analysis

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DRTS

Alpha Tau Medical Ltd

(NASDAQ:DRTS)

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Neutral 49 (OpenAI - 5.2)
Rating:49Neutral
Price Target:
$7.00
▲(2.34% Upside)
Action:ReiteratedDate:03/12/26
The score is primarily held down by very weak financial performance (no revenue, widening losses, and significant ongoing cash burn), partially offset by a comparatively improved balance sheet and moderate leverage. Technicals are neutral-to-slightly constructive on longer-term moving averages, while valuation remains challenged due to negative earnings and no dividend support.
Positive Factors
Regulatory validation (Japan approval)
Securing Shonin approval in Japan provides durable regulatory validation for Alpha DaRT as a first-in-kind intratumoral alpha therapy. This creates an initial commercial foothold, obliges post-market study data generation, and materially reduces regulatory execution risk regionally versus a company with no approvals.
Broad clinical program and pipeline breadth
A diversified clinical program across high-need indications lowers single-trial binary risk and creates multiple potential commercialization pathways. Simultaneous trials and planned basket studies build a multi-indication evidence base that can sustain long-term revenue channels if efficacy/safety are confirmed.
Improved balance sheet and moderate leverage
A material equity position and low reported debt-to-equity (≈0.16–0.20) provide longer runway flexibility compared with deeply levered peers. The recovery from prior negative equity signals improved capital structure, reducing short-term liquidation risk and supporting near-term clinical and initial commercial investments.
Negative Factors
No commercial revenue
Absent any product revenue, the business remains entirely pre-commercial; sustainable margins and profitability cannot be assessed until market uptake. This structural revenue void forces reliance on external financing and makes long-term viability contingent on successful trial outcomes and regulatory approvals.
Sustained cash burn
Consistent negative operating and free cash flow creates an ongoing financing need that pressures strategic choices. Heavy burn limits the company's ability to scale manufacturing, commercial launch, or expand trials without dilution or debt, increasing execution risk if markets tighten or milestones slip.
Widening net losses and profitability risk
Growing annual losses and persistently negative ROE erode shareholder value over time and increase the probability of further capital raises. If clinical or regulatory setbacks occur, accumulated losses could force dilution, delay commercialization, or constrain investment in critical R&D and manufacturing scale-up.

Alpha Tau Medical Ltd (DRTS) vs. SPDR S&P 500 ETF (SPY)

Alpha Tau Medical Ltd Business Overview & Revenue Model

Company DescriptionAlpha Tau Medical Ltd., a clinical-stage oncology therapeutics company, engages in research, development, and commercialization of diffusing alpha-emitters radiation therapy (Alpha DaRT) for the treatment of solid cancer In Israel and the United States. Its Alpha-DaRT technology used in clinical trials for skin, oral, pancreatic, and breast cancers; and preclinical studies for hepatic cell carcinoma, glioblastoma multiforme, lung cancer, and others. The company was incorporated in 2015 and is headquartered in Jerusalem, Israel.
How the Company Makes Moneynull

Alpha Tau Medical Ltd Financial Statement Overview

Summary
Financial performance is weak overall: the company has reported zero revenue across 2020–2025, losses widened materially (net loss to ~$42.6M in 2025), and cash burn remains heavy (operating cash flow about -$26.7M and free cash flow about -$32.8M in 2025). The balance sheet is a relative positive with moderate leverage and a shift to positive equity since 2022, but persistent losses keep financing/dilution risk elevated.
Income Statement
12
Very Negative
The income statement is very weak: the company reports zero revenue across the annual periods provided (2020–2025), while gross profit is consistently negative and losses remain substantial. Net loss widened from about $8.9M (2020) to ~$42.6M (2025), indicating increasing operating expense burden without an offsetting revenue ramp. Profitability is structurally negative (negative EBITDA and net income each year), which is typical for early-stage biotech but still a clear near-term earnings risk.
Balance Sheet
64
Positive
The balance sheet is relatively stronger than the income statement. Leverage appears moderate in recent years, with debt-to-equity around ~0.16–0.20 during 2023–2025 and total debt of ~$13.7M against ~$77.1M equity in 2025. A key positive is the turnaround from negative equity in 2020–2021 to sizable positive equity from 2022 onward. The main weakness is persistent negative returns on equity in recent years (e.g., 2025), reflecting ongoing losses and continued dilution/erosion risk if losses persist.
Cash Flow
23
Negative
Cash flow quality is weak due to sustained cash burn. Operating cash flow is negative every year and worsened to about -$26.7M in 2025 (from about -$19.8M in 2024), with free cash flow also negative and declining to about -$32.8M in 2025. While free cash flow is generally in line with (and sometimes less negative than) net income, the consistent outflows imply reliance on external funding and elevate liquidity/financing risk if capital markets tighten.
BreakdownDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue0.000.000.000.000.00
Gross Profit-1.23M-1.10M-1.07M-979.00K-776.00K
EBITDA-41.06M-30.30M-28.03M-32.74M-13.21M
Net Income-42.63M-31.75M-29.16M-33.76M-27.27M
Balance Sheet
Total Assets106.58M86.20M107.39M120.15M42.22M
Cash, Cash Equivalents and Short-Term Investments76.90M59.60M81.79M104.53M31.32M
Total Debt13.73M12.54M13.28M5.19M53.96M
Total Liabilities29.48M23.54M22.91M14.49M76.99M
Stockholders Equity77.10M62.67M84.47M105.66M-34.78M
Cash Flow
Free Cash Flow-32.76M-22.02M-24.36M-24.78M-14.74M
Operating Cash Flow-26.68M-19.78M-17.96M-23.88M-11.81M
Investing Cash Flow-20.59M20.77M18.68M-89.94M19.27M
Financing Cash Flow45.77M25.00K5.30M96.91M111.00K

Alpha Tau Medical Ltd Technical Analysis

Technical Analysis Sentiment
Positive
Last Price6.84
Price Trends
50DMA
7.06
Positive
100DMA
5.66
Positive
200DMA
4.53
Positive
Market Momentum
MACD
>-0.01
Positive
RSI
52.12
Neutral
STOCH
68.59
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For DRTS, the sentiment is Positive. The current price of 6.84 is below the 20-day moving average (MA) of 7.27, below the 50-day MA of 7.06, and above the 200-day MA of 4.53, indicating a neutral trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 52.12 is Neutral, neither overbought nor oversold. The STOCH value of 68.59 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for DRTS.

Alpha Tau Medical Ltd Risk Analysis

Alpha Tau Medical Ltd disclosed 85 risk factors in its most recent earnings report. Alpha Tau Medical Ltd reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Alpha Tau Medical Ltd Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
57
Neutral
$1.66B-11.68-90.96%-52.08%-69.35%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$638.07M-8.74-57.29%-22.82%
49
Neutral
$412.60M-13.08-38.92%80.95%
46
Neutral
$479.53M-4.99-90.49%4.97%
45
Neutral
$464.60M-1.33-91.83%-67.41%
42
Neutral
$428.01M-3.90-69.67%-11.41%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
DRTS
Alpha Tau Medical Ltd
7.25
4.59
172.56%
LRMR
Larimar Therapeutics
4.40
1.85
72.55%
CAPR
Capricor Therapeutics
30.56
17.68
137.27%
BNTC
Benitec Biopharma
12.01
-3.33
-21.71%
AURA
Aura Biosciences Inc
6.74
-0.80
-10.61%
LXEO
Lexeo Therapeutics, Inc.
6.57
3.46
111.25%

Alpha Tau Medical Ltd Corporate Events

Alpha Tau Posts Wider 2025 Loss as Japanese Approval and U.S. Trial Progress Mark Pivotal Year
Mar 9, 2026

Alpha Tau Medical Ltd., the developer of the Alpha DaRT alpha-radiation cancer therapy, reported its full-year 2025 results on March 9, 2026, alongside a broad clinical and regulatory update. The company is expanding into major cancer indications such as pancreatic, prostate, and brain tumors, while scaling manufacturing at its New Hampshire facility to support anticipated commercial demand.

In recent months, Alpha Tau secured Japanese marketing approval for Alpha DaRT in unresectable locally advanced or recurrent head and neck cancer, its first approval outside Israel, and obtained FDA approval to launch a U.S. pilot trial in locally recurrent prostate cancer. It also treated the first patient in a U.S. recurrent glioblastoma trial, submitted the first module of a U.S. PMA for recurrent cutaneous squamous cell carcinoma, and reported encouraging pancreatic cancer data at the ASCO GI Symposium.

Looking ahead, the company targets completion of patient recruitment in its pivotal U.S. ReSTART skin cancer trial by the end of Q1 2026, its U.S. pancreatic cancer pilot study in Q2 2026, and its recurrent glioblastoma feasibility trial in the second half of 2026. These milestones, coupled with post-marketing surveillance obligations in Japan, are set to shape Alpha Tau’s regulatory and commercial trajectory across multiple high-need oncology markets.

Financially, Alpha Tau’s R&D expenses rose to $32.1 million in 2025 from $27.0 million in 2024, and G&A costs also increased, driving a wider net loss of $42.6 million, or $0.53 per share, versus a $31.8 million loss a year earlier. Despite the higher burn, the company ended 2025 with $76.9 million in cash, cash equivalents, and deposits, up from $62.9 million, supporting ongoing clinical development and pre-commercial activities.

The most recent analyst rating on (DRTS) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Wins First Overseas Approval as Japan Clears Alpha DaRT Cancer Therapy
Feb 24, 2026

On February 24, 2026, Alpha Tau Medical Ltd. announced that Japan’s Ministry of Health, Labour and Welfare granted Shonin marketing approval for its Alpha DaRT therapy to treat unresectable locally advanced or locally recurrent head and neck cancer. The decision follows rigorous review by Japan’s Pharmaceuticals and Medical Devices Agency and marks the first approval of Alpha DaRT outside Israel, signaling regulatory validation of this first-in-kind intratumoral alpha-radiation platform.

As a condition of approval, Alpha Tau will conduct a post‑market surveillance study of 66 patients at five leading Japanese centers to further assess safety and performance in real-world practice. Backed by longstanding collaboration with distributor HekaBio and strong support from Japanese medical societies and clinicians, the early Japanese authorization—preceding similar decisions in the U.S. and Europe—could enhance Alpha Tau’s standing in global oncology and accelerate clinical adoption in head and neck cancer.

The most recent analyst rating on (DRTS) stock is a Hold with a $7.50 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Outlines Aggressive 2026 Clinical Schedule and Manufacturing Ramp for Alpha DaRT Cancer Therapy
Jan 29, 2026

On January 29, 2026, Alpha Tau Medical issued a shareholder letter outlining an intensifying clinical and pre-commercial agenda for 2026, highlighted by five concurrent U.S. trials of its Alpha DaRT therapy in skin, pancreatic, brain and prostate cancers, additional studies in Europe and Israel, and preparations for a large basket trial in the UK. The company expects to complete patient recruitment in its IMPACT pancreatic cancer trial by the end of the first quarter of 2026 with initial data anticipated by year-end, is targeting first results from its U.S. glioblastoma study around the end of 2026, and is awaiting a near-term regulatory decision in Japan on Alpha DaRT for recurrent head and neck cancer that could mark its first commercial approval outside Israel. Alongside ongoing data generation from its pivotal ReSTART skin cancer trial and planned exploration of Alpha DaRT in combination with checkpoint inhibitors for advanced head and neck cancer, Alpha Tau is ramping U.S. manufacturing capacity, advancing a modular PMA submission to the FDA, and building organizational and production infrastructure in the U.S. and Israel, signaling that it is positioning itself for potential commercialization and broader adoption of its platform if upcoming clinical and regulatory milestones are favorable.

The most recent analyst rating on (DRTS) stock is a Hold with a $7.50 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical Unveils Strong Pancreatic Cancer Alpha DaRT Data Ahead of ASCO GI 2026
Jan 6, 2026

On January 6, 2026, Alpha Tau Medical reported final results from its first-in-human pancreatic ductal adenocarcinoma study in Montreal, showing an 81% disease control rate across 32 patients treated with its Alpha DaRT therapy, rising to 87% when excluding the first two low-dose feasibility patients, along with a 22–23% objective response rate and a favorable safety profile. Complementary data from 23 patients demonstrated preservation of key immune and inflammatory markers one month after treatment, including stable neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios and a marked reduction in IL-6 levels, suggesting an immune-preserving, less inflammatory radiation profile that could support combination with systemic therapies such as chemotherapy or immunotherapy; these findings reinforce Alpha Tau’s strategic focus on pancreatic cancer, underpin ongoing U.S. and European trials, and may strengthen the company’s positioning as it seeks future regulatory approval for Alpha DaRT in this high-need indication.

The most recent analyst rating on (DRTS) stock is a Buy with a $9.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Files First FDA PMA Module for Alpha DaRT Skin Cancer Therapy
Jan 5, 2026

On January 5, 2026, Alpha Tau Medical announced it has submitted the first module of its pre-market approval application to the U.S. Food and Drug Administration for Alpha DaRT in the treatment of recurrent cutaneous squamous cell carcinoma in patients who are not candidates for surgery or standard radiation and lack curative systemic options. The FDA has allowed the company to use a modular PMA approach, enabling staged review of non-clinical and other data, and the initial module focuses on comprehensive non-clinical documentation; this step, taken in parallel with the ongoing multi-center ReSTART pivotal study that is expected to complete patient recruitment in the first quarter of 2026, marks a key regulatory milestone that could help streamline U.S. review and potentially strengthen Alpha Tau’s position in the skin cancer treatment market if future modules and clinical results support approval.

The most recent analyst rating on (DRTS) stock is a Hold with a $5.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Alpha Tau Medical to Present Corporate Update at J.P. Morgan 2026 Healthcare Conference
Dec 18, 2025

On December 18, 2025, Alpha Tau Medical Ltd. announced that CEO Uzi Sofer and CFO Raphi Levy will deliver a corporate overview and update at the J.P. Morgan 2026 Healthcare Conference in San Francisco on January 15, 2026, and will hold one-on-one meetings with institutional investors during the event. The presentation is expected to highlight the company’s recent achievements and outline upcoming data milestones for its Alpha DaRT solid-tumor therapy, signaling an effort to raise Alpha Tau’s visibility with global healthcare investors and potentially strengthen its position within the oncology therapeutics space as it advances toward further clinical and commercial development.

The most recent analyst rating on (DRTS) stock is a Buy with a $7.00 price target. To see the full list of analyst forecasts on Alpha Tau Medical Ltd stock, see the DRTS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Mar 12, 2026