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Cumberland Pharmaceuticals Inc (CPIX)
NASDAQ:CPIX
US Market

Cumberland Pharmaceuticals (CPIX) AI Stock Analysis

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CPIX

Cumberland Pharmaceuticals

(NASDAQ:CPIX)

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Neutral 51 (OpenAI - 5.2)
Rating:51Neutral
Price Target:
$4.00
▼(-15.25% Downside)
The score is held back primarily by weak financial performance (loss-making margins and slightly declining TTM revenue) and soft technical signals (below the 20-day average with negative MACD). A more constructive earnings-call outlook—driven by year-to-date revenue growth, partnerships, and pipeline progress—partially offsets these risks, while valuation is not supportive given the negative P/E and no dividend yield provided.
Positive Factors
High Gross Margin
An 84.49% gross margin indicates very strong unit economics for Cumberland's product portfolio, providing durable buffer to absorb SG&A or R&D spending. High gross margins support reinvestment in commercialization and clinical programs even if operating margins are currently negative.
Improved Leverage
Reduction in leverage to a 0.39 debt/equity ratio materially improves financial flexibility and lowers refinancing risk. With lower debt burden, the company can allocate cash to R&D, international launches, or partnerships without as much strain from interest obligations.
Regulatory/Clinical Progress
Fast Track designation for ifetroban, on top of prior Orphan and Rare Pediatric statuses and positive Phase 2 data, accelerates regulatory engagement and review timelines. This structurally strengthens the pipeline and could create a durable revenue stream in an underserved rare-disease cardiology niche.
Negative Factors
Negative Profitability
Persistent negative net margins and a negative ROE signal the company is not yet converting high gross margins into sustainable bottom-line returns. Continued losses constrain retained earnings, limit shareholder returns, and require ongoing cash or financing to support growth initiatives.
Declining TTM Revenue
Slight TTM revenue decline undermines scale benefits and raises questions about product demand stability. Without consistent top-line growth, fixed costs and R&D investments erode margins and make it harder to fund commercialization of new assets like ifetroban sustainably.
Product Competition & Supply Disruption
Increased generic substitution for Kristalose and reported shipment delays are structural risks to revenue durability. Competitive erosion and operational supply issues can permanently reduce market share for legacy products and force higher marketing or discounting to defend volumes.

Cumberland Pharmaceuticals (CPIX) vs. SPDR S&P 500 ETF (SPY)

Cumberland Pharmaceuticals Business Overview & Revenue Model

Company DescriptionCumberland Pharmaceuticals Inc., a specialty pharmaceutical company, focuses on the acquisition, development, and commercialization of prescription products for hospital acute care, gastroenterology, rheumatology, and oncology in the United States and internationally. The company offers Acetadote, an injection for the treatment of acetaminophen poisoning; Caldolor, an injection for the treatment of pain and fever; Kristalose, a prescription laxative oral solution for the treatment of chronic and acute constipation; Omeclamox-Pak for the treatment of Helicobacter pylori infection and duodenal ulcer disease; Vaprisol, an injection for treating euvolemic and hypervolemic hyponatremia; and Vibativ, an injection for the treatment of certain serious bacterial infections, including hospital-acquired and ventilator-associated bacterial pneumonia, as well as complicated skin and skin structure infections. It also develops RediTrex injection for the treatment of active rheumatoid, juvenile idiopathic, and severe psoriatic arthritis, as well as disabling psoriasis. In addition, the company is developing ifetroban, a product candidate that is in phase II clinical trial for the treatment of aspirin-exacerbated respiratory disease, systemic sclerosis, and duchenne muscular dystrophy; and has completed phase II clinical trial for the treatment of hepatorenal syndrome and portal hypertension. Further, it develops a clinical program for the use of ifetroban to treat progressive fibrosing interstitial lung diseases; and a product candidate that is in Phase II clinical trial for cholesterol reducing agent to use in the hospital setting. The company was incorporated in 1999 and is headquartered in Nashville, Tennessee.
How the Company Makes MoneyCumberland Pharmaceuticals generates revenue primarily through the sale of its pharmaceutical products to hospitals, clinics, and healthcare providers. The company's revenue model is based on direct product sales, as well as collaborations and partnerships with other pharmaceutical companies for distribution and marketing of its products. Key revenue streams include sales from its flagship drugs like Acetadote and Vaprisol, along with royalties and licensing fees from its partnered products. Additionally, strategic partnerships with healthcare institutions and distributors help expand its market reach and enhance its sales capabilities, contributing to its overall earnings.

Cumberland Pharmaceuticals Key Performance Indicators (KPIs)

Any
Any
Net Revenue by Product
Net Revenue by Product
Chart Insights
Data provided by:The Fly

Cumberland Pharmaceuticals Earnings Call Summary

Earnings Call Date:Nov 04, 2025
(Q3-2025)
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% Change Since: |
Next Earnings Date:Mar 10, 2026
Earnings Call Sentiment Positive
The earnings call highlighted strategic partnerships and international expansion, alongside strong revenue growth and clinical progress, which were slightly offset by shipment delays and increased competition. Overall, the sentiment of the call was positive, with more highlights than lowlights.
Q3-2025 Updates
Positive Updates
Strategic Partnership with RedHill Biopharma
Cumberland entered into a partnership with RedHill Biopharma to commercialize Talicia, an FDA-approved treatment for helicobacter pylori infections, showing a high eradication rate exceeding 90%.
International Expansion
Cumberland launched Vibativ in Saudi Arabia and received regulatory approval for ibuprofen injection in Mexico, expanding its international footprint.
Strong Revenue Growth
Year-to-date revenue grew 12% over the same period last year, with total revenues reaching $30.9 million for the first nine months of 2025.
Positive Cash Flow
Cumberland reported a positive cash flow from operations, amounting to $5 million through September 2025.
Ifetroban Clinical Progress
Positive top-line results from the FIGHT DMD trial for ifetroban in Duchenne muscular dystrophy were reported, showing significant improvements in cardiac function.
Negative Updates
Product Shipment Delays
Third quarter sales were impacted by a delay in Kristalose and Caldolor shipments.
Increased Generic Competition
Kristalose faced increased substitution by pharmacies in favor of generic alternatives, affecting its market share.
Adjusted Loss for the Quarter
The adjusted loss for the third quarter was $0.8 million or $0.06 a share.
Company Guidance
During Cumberland Pharmaceuticals' third-quarter 2025 financial call, the company announced several key developments. They reported $8.3 million in combined revenues for their FDA-approved brands during the quarter, with year-to-date revenues reaching $30.9 million, marking a 12% increase over the same period last year. Cumberland introduced Talicia, a new addition to their commercial product portfolio, aimed at treating helicobacter pylori infections, with U.S. net sales totaling $8 million in 2024. They formed a joint venture with RedHill Biopharma to commercialize Talicia in the U.S., investing $4 million over two years and sharing net revenues equally. The company achieved international milestones with the launch of Vibativ in Saudi Arabia and regulatory approval of ibuprofen injection in Mexico. Cumberland also highlighted ongoing clinical programs, with ifetroban being evaluated in several trials, including Duchenne muscular dystrophy, systemic sclerosis, and idiopathic pulmonary fibrosis. Financially, they recorded a third-quarter adjusted loss of $0.8 million or $0.06 per share, but year-to-date adjusted earnings reached $1.9 million or $0.13 per share. Cumberland ended the quarter with $66 million in total assets, including $15 million in cash, and has reduced total debt by $10 million since the end of 2024.

Cumberland Pharmaceuticals Financial Statement Overview

Summary
Financial statement scores point to weak profitability and slightly declining revenue (TTM revenue growth -1.89% and TTM net margin -8.06%) despite strong gross margin (84.49%). Balance sheet leverage improved (debt-to-equity 0.39), and cash flow is positive with relatively strong free-cash-flow-to-net-income (0.98), but negative free cash flow growth and negative ROE keep the overall financial profile middling.
Income Statement
45
Neutral
Cumberland Pharmaceuticals shows a declining revenue trend with a negative revenue growth rate of -1.89% in the TTM. The company has consistently reported negative net profit margins, with the TTM net profit margin at -8.06%. Despite a strong gross profit margin of 84.49% in the TTM, the negative EBIT and EBITDA margins indicate operational inefficiencies and challenges in managing operating expenses.
Balance Sheet
50
Neutral
The company's debt-to-equity ratio improved to 0.39 in the TTM from 0.90 in the previous year, indicating a reduction in leverage. However, the return on equity remains negative, reflecting ongoing profitability challenges. The equity ratio is relatively stable, suggesting a balanced asset structure, but the negative ROE highlights the need for improved profitability.
Cash Flow
55
Neutral
Cumberland Pharmaceuticals has shown improvement in cash flow metrics, with a positive operating cash flow and a high free cash flow to net income ratio of 0.98 in the TTM. However, the free cash flow growth rate is negative, indicating potential challenges in sustaining cash flow generation. The operating cash flow to net income ratio of 0.28 suggests moderate cash flow efficiency.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue41.28M37.87M39.55M42.01M35.99M37.44M
Gross Profit34.88M31.28M33.49M32.89M27.17M28.79M
EBITDA2.68M182.42K2.49M332.92K-857.83K-1.56M
Net Income-3.33M-6.48M-6.28M-5.57M-3.51M-3.34M
Balance Sheet
Total Assets65.90M75.58M81.78M92.93M84.46M96.46M
Cash, Cash Equivalents and Short-Term Investments15.20M17.96M18.32M19.76M27.04M24.75M
Total Debt10.24M20.57M18.43M20.96M16.06M19.26M
Total Liabilities40.10M53.04M52.52M56.95M41.86M49.59M
Stockholders Equity26.12M22.85M29.60M36.27M42.81M46.99M
Cash Flow
Free Cash Flow6.71M-791.90K5.64M6.38M5.99M3.30M
Operating Cash Flow6.83M-612.19K6.09M8.45M6.34M5.42M
Investing Cash Flow-1.66M57.84K-105.69K-13.67M-501.89K-1.76M
Financing Cash Flow-7.44M196.90K-7.42M-2.06M-3.55M-7.12M

Cumberland Pharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price4.72
Price Trends
50DMA
3.65
Negative
100DMA
3.30
Positive
200DMA
3.69
Negative
Market Momentum
MACD
-0.06
Positive
RSI
41.07
Neutral
STOCH
28.49
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CPIX, the sentiment is Negative. The current price of 4.72 is above the 20-day moving average (MA) of 4.22, above the 50-day MA of 3.65, and above the 200-day MA of 3.69, indicating a bearish trend. The MACD of -0.06 indicates Positive momentum. The RSI at 41.07 is Neutral, neither overbought nor oversold. The STOCH value of 28.49 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CPIX.

Cumberland Pharmaceuticals Risk Analysis

Cumberland Pharmaceuticals disclosed 1 risk factors in its most recent earnings report. Cumberland Pharmaceuticals reported the most risks in the "Legal & Regulatory" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Cumberland Pharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
53
Neutral
$76.04M-2.47-24.48%9.21%58.12%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$58.93M-15.40-13.08%12.21%69.91%
47
Neutral
$98.67M-0.23-114.52%-86.05%24.17%
45
Neutral
$30.42M-1.29-53.29%-65.77%38.61%
42
Neutral
$40.59M-6.27-16.67%-23.60%-179.33%
40
Underperform
$12.27M-0.0752.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CPIX
Cumberland Pharmaceuticals
3.59
-1.75
-32.77%
ASRT
Assertio Therapeutics
11.85
-0.27
-2.23%
RMTI
Rockwell Med
1.03
-0.95
-47.98%
SCYX
SCYNEXIS
0.72
-0.44
-37.59%
KALA
KALA BIO
0.40
-10.33
-96.28%
IXHL
Incannex Healthcare Limited Sponsored ADR
0.25
-1.95
-88.64%

Cumberland Pharmaceuticals Corporate Events

Business Operations and StrategyProduct-Related Announcements
Cumberland Pharmaceuticals Wins Fast Track for Ifetroban
Positive
Feb 4, 2026

On February 4, 2026, Cumberland Pharmaceuticals announced that the U.S. Food and Drug Administration granted Fast Track Designation to its oral thromboxane receptor antagonist ifetroban, which targets a fatal form of heart disease in Duchenne muscular dystrophy patients. The designation, which follows prior Orphan Drug and Rare Pediatric Disease status for ifetroban and is supported by positive Phase 2 data showing a 5.4% improvement in left ventricular ejection fraction over 12 months, is expected to accelerate regulatory interactions and review, potentially strengthening Cumberland’s position in rare disease cardiology and offering new hope in an area where no approved therapies currently exist for DMD-related heart disease.

The most recent analyst rating on (CPIX) stock is a Hold with a $4.00 price target. To see the full list of analyst forecasts on Cumberland Pharmaceuticals stock, see the CPIX Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Feb 04, 2026