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KALA BIO (KALA)
NASDAQ:KALA

KALA BIO (KALA) AI Stock Analysis

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KALA

KALA BIO

(NASDAQ:KALA)

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Underperform 40 (OpenAI - 5.2)
Rating:40Underperform
Price Target:
$0.50
▼(-19.19% Downside)
The score is driven primarily by very weak financial performance (near-zero revenue, large ongoing losses, negative equity, and substantial cash burn). Technicals are also negative with the stock below key moving averages and a negative MACD. Corporate events are mixed—debt overhang reduction helps, but Nasdaq compliance issues materially elevate risk; valuation metrics provide limited support given negative earnings and no dividend.
Positive Factors
Debt overhang eliminated
Settling the ~$10.6M Oxford liability materially reduces near-term creditor pressure and covenant/default risk. This improves financial flexibility and cash flow optionality for financing R&D and clinical programs, making capital structure management and strategic partnerships easier over the medium term.
Demonstrated access to equity capital
Successful direct and preferred offerings plus an ATM program show repeated investor willingness to fund the company. Sustained access to equity capital is a structural enabler for a clinical-stage biotech to progress trials, fund operations, and pursue partnerships without revenue, reducing immediate solvency risk.
Leadership and strategic financing alignment
A new CEO tied to financing transactions signals active governance and strategic focus on stabilizing operations. Leadership that secures committed funding and coordinates settlements can improve execution of clinical and capital plans, impacting long-term ability to advance assets and negotiate partnerships.
Negative Factors
Near-zero recurring revenue and heavy cash burn
With essentially no product revenue and persistent ~-$32M TTM operating cash burn, the company lacks an internal cash-generating engine. This structural dependence on external financing increases dilution risk and constrains long-term R&D planning if capital markets tighten or investor appetite wanes.
Negative equity and elevated leverage
Negative shareholders' equity and material outstanding debt weaken the balance sheet, limiting borrowing capacity and increasing refinancing risk. A strained capital structure reduces strategic optionality, raises creditor negotiation leverage, and increases the likelihood that future funding will be dilutive or costly.
Nasdaq listing compliance risk
A Nasdaq deficiency notice creates a persistent governance and market-access risk: potential delisting or remedy actions (reverse split) can reduce liquidity, deter institutional investors, and complicate equity financing or partnering, making long-term capital access and shareholder stability more uncertain.

KALA BIO (KALA) vs. SPDR S&P 500 ETF (SPY)

KALA BIO Business Overview & Revenue Model

Company DescriptionKala Bio, Inc. is a biopharmaceutical company. It focuses on the development and commercialization of therapeutics using proprietary nanoparticle-based mucus penetrating particles with an initial focus on the treatment of eye diseases. The company was founded by Justin Hanes, Robert S. Langer and Colin R. Gardner in 2009 and is headquartered in Arlington, MA.
How the Company Makes MoneyKala Pharmaceuticals makes money through the commercialization of its proprietary eye care products. The company's revenue model is primarily based on the sales of its FDA-approved drugs, which are marketed and distributed to healthcare providers and patients. Revenue streams include direct sales of products such as EYSUVIS and INVELTYS, which are specifically developed for treating ocular conditions. In addition, Kala Pharmaceuticals may engage in strategic partnerships or licensing agreements to enhance its product distribution and market reach, further contributing to its earnings.

KALA BIO Financial Statement Overview

Summary
Financials are very weak: revenue is near-zero (~$0.25M TTM) versus large losses (net income about -$35.8M TTM). Cash burn remains heavy (operating cash flow about -$32.0M TTM; free cash flow about -$32.1M) and stockholders’ equity is negative (~-$8.7M), indicating elevated funding and balance-sheet risk despite some improvement in losses and debt reduction.
Income Statement
6
Very Negative
Results remain deeply unprofitable, with TTM (Trailing-Twelve-Months) net income of about -$35.8M on only ~$0.25M of revenue, implying extreme negative margins and no meaningful operating leverage. Revenue has effectively been near-zero in recent years (2023–2024) versus modest levels earlier (e.g., 2021–2022), highlighting a weak and inconsistent top-line base. A relative positive is that annual net losses have narrowed substantially from 2020–2021 levels, but the business is still far from break-even.
Balance Sheet
18
Very Negative
Leverage is elevated and has become riskier: TTM (Trailing-Twelve-Months) stockholders’ equity is negative (~-$8.7M), while total debt remains sizable (~$29.9M), indicating a strained capital structure. Total assets have also declined materially versus prior years, reducing financial flexibility. Debt has come down from 2020–2023 levels, which helps, but negative equity and ongoing losses keep balance-sheet risk high.
Cash Flow
10
Very Negative
Cash burn remains heavy: TTM (Trailing-Twelve-Months) operating cash flow is about -$32.0M and free cash flow about -$32.1M, indicating continued reliance on external funding. Cash burn improved versus 2024 on an annual basis (free cash flow growth is positive in TTM), but cash generation is still firmly negative and not supported by a durable revenue engine. Free cash flow is roughly in line with net losses, suggesting limited non-cash offsets and persistent underlying cash consumption.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue254.00K0.000.003.89M11.24M6.36M
Gross Profit-8.00K-259.00K-303.00K1.33M7.14M3.19M
EBITDA-30.98M-40.98M-36.08M-36.70M-131.96M-92.90M
Net Income-35.84M-38.51M-42.20M-44.82M-142.60M-104.33M
Balance Sheet
Total Assets25.02M55.48M55.95M86.82M139.43M221.61M
Cash, Cash Equivalents and Short-Term Investments21.10M51.18M50.90M70.50M92.14M153.54M
Total Debt29.94M32.25M36.32M42.95M80.19M100.92M
Total Liabilities1.11M43.15M48.45M67.85M122.62M121.61M
Stockholders Equity-8.66M12.33M7.50M18.97M16.80M100.00M
Cash Flow
Free Cash Flow-32.09M-29.59M-28.54M-79.22M-109.12M-92.64M
Operating Cash Flow-32.03M-29.38M-27.93M-78.91M-108.23M-90.69M
Investing Cash Flow-84.00K-208.00K-429.00K62.72M70.80M-78.21M
Financing Cash Flow4.01M29.88M8.51M-7.94M42.55M160.63M

KALA BIO Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.62
Price Trends
50DMA
0.67
Negative
100DMA
2.59
Negative
200DMA
4.47
Negative
Market Momentum
MACD
-0.07
Positive
RSI
27.32
Positive
STOCH
7.68
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For KALA, the sentiment is Negative. The current price of 0.62 is above the 20-day moving average (MA) of 0.57, below the 50-day MA of 0.67, and below the 200-day MA of 4.47, indicating a bearish trend. The MACD of -0.07 indicates Positive momentum. The RSI at 27.32 is Positive, neither overbought nor oversold. The STOCH value of 7.68 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for KALA.

KALA BIO Risk Analysis

KALA BIO disclosed 67 risk factors in its most recent earnings report. KALA BIO reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

KALA BIO Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$26.04M83.910.27%75.19%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
51
Neutral
$58.93M-15.40-13.08%12.21%69.91%
45
Neutral
$30.42M-1.29-53.29%-65.77%38.61%
42
Neutral
$40.59M-6.27-16.67%-23.60%-179.33%
40
Underperform
$12.27M-0.0752.39%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
KALA
KALA BIO
0.40
-10.33
-96.28%
RMTI
Rockwell Med
1.00
-0.98
-49.49%
TXMD
TherapeuticsMD
2.19
1.18
116.83%
SCYX
SCYNEXIS
0.69
-0.47
-40.52%
CPIX
Cumberland Pharmaceuticals
3.59
-1.75
-32.77%

KALA BIO Corporate Events

Business Operations and StrategyPrivate Placements and FinancingRegulatory Filings and ComplianceShareholder MeetingsStock Split
KALA BIO expands preferred financing and shareholder authorizations
Neutral
Feb 2, 2026

On November 24, 2025, KALA BIO completed the first closing of a private placement under a previously disclosed agreement by issuing 900,000 shares of Series AA Convertible Non-Redeemable Preferred Stock at $2.00 per share, raising $1.8 million and creating the potential issuance of 49,500,000 common shares upon conversion. After a series of transfers of purchase rights among investors in December 2025 and January 2026, the company entered a new Securities Purchase Agreement on January 30, 2026, with a group of Series AAA investors and completed a second closing the same day, issuing 2,100,000 shares of Series AAA Preferred Stock at $2.00 per share for $4.2 million in gross proceeds, with each Series AAA share convertible into 420 common shares, or up to 882,000,000 common shares in total; the offering was conducted as a private placement exempt from SEC registration. At its recent Annual Meeting, where 15,489,822 common shares were represented, shareholders elected three Class II directors to terms ending at the 2028 annual meeting, approved executive compensation on an advisory basis, ratified the appointment of HTL International, LLC as independent auditor for 2025, authorized the issuance of common stock upon conversion of the Series AA and Series AAA preferred shares in line with Nasdaq rules, and approved an increase in authorized common stock to 1.5 billion shares as well as a board‑discretionary reverse stock split in a range of 1‑for‑2 to 1‑for‑100, actions that collectively position KALA BIO to significantly expand its equity base and maintain listing compliance while potentially causing substantial dilution to existing shareholders.

The most recent analyst rating on (KALA) stock is a Sell with a $0.50 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
KALA BIO Receives Nasdaq Notice on Listing Compliance
Negative
Jan 23, 2026

On January 20, 2026, Kala Bio disclosed that it had received a notice from Nasdaq stating that, based on the company’s closing bid prices between December 3, 2025 and January 16, 2026, its shares had traded below the $1.00 minimum required for continued listing on the Nasdaq Capital Market. The company has been granted a 180-day compliance period, until July 20, 2026, to restore its share price to at least $1.00 for ten consecutive business days, with the possibility of an additional 180-day extension if it meets other listing criteria and commits to a remedy such as a reverse stock split; failure to regain compliance could ultimately lead to delisting, although the notice does not immediately affect trading of the shares.

The most recent analyst rating on (KALA) stock is a Sell with a $0.58 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Private Placements and Financing
KALA BIO Launches At-the-Market Equity Offering Program
Neutral
Jan 8, 2026

On January 8, 2026, KALA BIO, Inc. entered into an at-the-market equity offering agreement with H.C. Wainwright & Co., allowing the company to issue and sell up to $15 million of its common stock from time to time through Wainwright as sales agent or, in certain cases, principal. Under the arrangement, KALA BIO retains full discretion over sales parameters, pays a 3% commission on gross proceeds and certain expense reimbursements to Wainwright, and may suspend or opt not to sell shares at any time, meaning the program primarily creates financing flexibility and potential access to incremental capital rather than immediately altering the company’s capital structure.

The most recent analyst rating on (KALA) stock is a Hold with a $0.60 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresPrivate Placements and FinancingRegulatory Filings and Compliance
KALA BIO eliminates debt overhang through equity settlements
Positive
Jan 6, 2026

On December 30, 2025, KALA BIO entered into a series of equity-based settlements, agreeing to issue 900,000 common shares to Baker Bros. Advisors to resolve claims over participation rights and securing a six‑month voting proxy over those and certain other Baker Bros. shares, 2,200,000 shares to LifeSci Capital to settle financial advisory fee obligations, and 1,100,000 shares to Delaware IR to satisfy a $600,000 marketing and advertising consulting liability via stock with a make‑whole feature tied to sale proceeds. That same day, the company issued a total of 4,600,000 unregistered common shares in private transactions—4.2 million under these settlements and 400,000 to employees—and later disclosed that, following a $2 million payment completed by December 26, 2025, it had fully extinguished approximately $10.6 million of debt owed to Oxford Finance, a move management described on January 5, 2026 as a transformational step that removes a significant debt overhang, increases stockholders’ equity and improves KALA BIO’s financial flexibility, while also using equity awards as inducements to hire four new employees.

The most recent analyst rating on (KALA) stock is a Hold with a $0.59 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Business Operations and StrategyFinancial DisclosuresRegulatory Filings and Compliance
Kala Bio fully settles loan, strengthens balance sheet
Positive
Jan 2, 2026

On December 26, 2025, Kala Bio, Inc. paid $2 million to Oxford Finance, LLC under a previously disclosed Loan Settlement Agreement linked to prior events of default under a 2021 Loan and Security Agreement involving the company and its subsidiary Combangio, Inc. With this payment, Kala Bio’s approximately $10.6 million aggregate liability to Oxford was fully settled and released, eliminating its obligations under both the settlement and the original loan, which strengthens the company’s balance sheet and resolves a significant debt-related overhang for stakeholders.

The most recent analyst rating on (KALA) stock is a Sell with a $0.55 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Business Operations and StrategyExecutive/Board ChangesPrivate Placements and FinancingShareholder Meetings
KALA BIO Directors Plan Conditional Resignations Tied to Vote
Neutral
Dec 29, 2025

On December 19, 2025, six directors of KALA BIO—Marjan Farid, M.D., Andrew I. Koven, C. Daniel Myers, Todd Bazmore, Mark Iwicki, and Howard B. Rosen—submitted conditional resignations that would become effective immediately after the company’s 2025 annual meeting if shareholders approve both the issuance of common stock upon conversion of certain preferred shares and an increase in authorized common stock. The move, which the company stated was not due to any disagreement over operations, policies or practices, would significantly reshape KALA BIO’s board composition after the 2025 annual meeting, while David Lazar is expected to remain on the board as a Class II director regardless of the vote outcome, highlighting governance changes tied directly to forthcoming capital-structure decisions.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Executive/Board ChangesPrivate Placements and FinancingShareholder Meetings
KALA BIO Announces New CEO and Funding Deal
Neutral
Dec 16, 2025

KALA BIO has scheduled its next annual meeting of stockholders for January 30, 2026, with stockholder proposals due by December 27, 2025. The company has entered into a Convertible Loan Agreement and a Securities Purchase Agreement with David Lazar, resulting in a $375,000 loan and a $6.0 million private placement of preferred shares. David Lazar has been appointed as CEO and a director, and he has sold his rights to purchase Series AAA Preferred Shares to AK Holdings Group Inc., retaining his Series AA shares and loan agreement.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
KALA BIO Raises $10M in Direct Offering
Neutral
Dec 5, 2025

On December 4, 2025, KALA BIO, Inc. entered into a securities purchase agreement with an institutional investor to issue and sell 900,000 shares of common stock and pre-funded warrants for up to 9,100,000 shares, raising $10 million in a registered direct offering. The offering closed on December 5, 2025, with H.C. Wainwright & Co. as the exclusive placement agent. The company plans to use the net proceeds for debt repayment and general corporate purposes. The agreement includes restrictions on further issuance of common stock for a specified period, impacting KALA’s financial strategy and market operations.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Executive/Board ChangesPrivate Placements and Financing
KALA BIO Raises $1.8M in Preferred Stock Offering
Positive
Nov 25, 2025

On November 23, 2025, KALA BIO entered into a Securities Purchase Agreement to issue Series AA and Series AAA Convertible Non-Redeemable Preferred Stock, raising up to $6 million. The first closing occurred on November 24, 2025, with $1.8 million raised, and a second closing is expected by March 31, 2026, contingent on stockholder approvals. Additionally, KALA BIO settled a loan with Oxford, reducing outstanding obligations by $7 million through a cash payment and stock issuance. The company also announced leadership changes, including the appointment of David Lazar as CEO, and a voting agreement with Oxford to support board proposals.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on KALA BIO stock, see the KALA Stock Forecast page.

Delistings and Listing ChangesRegulatory Filings and Compliance
Kala Pharmaceuticals Faces Nasdaq Compliance Challenge
Negative
Nov 12, 2025

On November 10, 2025, KALA BIO, Inc. received a deficiency letter from Nasdaq indicating non-compliance with the Minimum Market Value of Listed Securities Requirement, as its market value was below $35 million for 30 consecutive business days. The company has until May 11, 2026, to regain compliance, failing which it may face delisting. KALA BIO intends to monitor its market value and consider options to meet the Nasdaq requirements.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Kala Pharmaceuticals stock, see the KALA Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
Kala Pharmaceuticals Secures Convertible Loan Amid Challenges
Negative
Nov 10, 2025

On November 9, 2025, Kala Pharmaceuticals entered into a Convertible Loan Agreement with an individual investor for a loan of up to $375,000. The loan will be used to negotiate additional investment transactions and prepare a quarterly report. The agreement allows the lender to convert the loan into company shares or demand repayment in cash, especially if a liquidity event occurs. This move comes as the company faces financial difficulties, with Oxford Finance LLC previously planning to foreclose on its assets. Kala Pharmaceuticals aims to use this loan to explore strategic options, including potential sales or mergers, although there is no assurance of success.

The most recent analyst rating on (KALA) stock is a Hold with a $1.50 price target. To see the full list of analyst forecasts on Kala Pharmaceuticals stock, see the KALA Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 24, 2026