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Collplant Holdings (CLGN)
NASDAQ:CLGN
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Collplant Holdings (CLGN) AI Stock Analysis

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CLGN

Collplant Holdings

(NASDAQ:CLGN)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
$0.39
▼(-73.91% Downside)
Action:ReiteratedDate:04/17/26
The score is driven primarily by weak financial performance (losses, inconsistent revenue, and sustained cash burn) and bearish technicals (price far below key moving averages with negative MACD and weak RSI/Stoch). Valuation provides little support because the company is unprofitable and does not pay a dividend.
Positive Factors
Robust global IP protection for photocurable filler and bioinks
Broad patent coverage across major aesthetics and bioprinting markets creates a durable competitive moat for CollPlant’s rhCollagen platform. Validated IP through 2038–2039 supports licensing, partner exclusivity and long‑term royalty potential while raising barriers to entry for competitors.
Negative Factors
Persistent negative operating and free cash flow
Sustained negative cash generation necessitates recurring external financing, diluting shareholders and creating execution risk. Heavy cash burn constrains the company’s ability to fund clinical paths, scale manufacturing, or execute commercial launches without material financing or partner milestone receipts.
Read all positive and negative factors
Positive Factors
Negative Factors
Robust global IP protection for photocurable filler and bioinks
Broad patent coverage across major aesthetics and bioprinting markets creates a durable competitive moat for CollPlant’s rhCollagen platform. Validated IP through 2038–2039 supports licensing, partner exclusivity and long‑term royalty potential while raising barriers to entry for competitors.
Read all positive factors

Collplant Holdings (CLGN) vs. SPDR S&P 500 ETF (SPY)

Collplant Holdings Business Overview & Revenue Model

Company Description
CollPlant Biotechnologies Ltd., a regenerative and aesthetic medicine company, focuses on three-dimensional (3D) bioprinting of tissues and organs, and medical aesthetics in the United States, Canada, and Europe. Its products are based on recombin...
How the Company Makes Money
CollPlant makes money primarily by monetizing its proprietary rhCollagen technology platform through (1) collaboration and development agreements, (2) licensing and related intellectual property (IP) payments, and (3) sales of collagen-based produ...

Collplant Holdings Earnings Call Summary

Earnings Call Date:Mar 26, 2025
(Q4-2024)
|
% Change Since: |
Next Earnings Date:Jun 03, 2026
Earnings Call Sentiment Neutral
Despite significant advancements in preclinical programs and continued collaboration with AbbVie, the company experienced a sharp decline in annual revenue and increased net losses, presenting a mixed financial outlook.
Positive Updates
Photocurable Dermal Filler Preclinical Success
The photocurable dermal filler candidate is in the preclinical phase, targeting a market valued at approximately $6.3 billion with a compound annual growth rate of 10%. Positive feedback from leaders in aesthetic medicine suggests it could be a game-changer for facial plastic surgery.
Negative Updates
Significant Revenue Decline
Revenue for the year ended December 31, 2024, was $515,000, a sharp decrease from $11 million in 2023, mainly due to a $10 million milestone payment in 2023 not repeated in 2024.
Read all updates
Q4-2024 Updates
Negative
Photocurable Dermal Filler Preclinical Success
The photocurable dermal filler candidate is in the preclinical phase, targeting a market valued at approximately $6.3 billion with a compound annual growth rate of 10%. Positive feedback from leaders in aesthetic medicine suggests it could be a game-changer for facial plastic surgery.
Read all positive updates
Company Guidance
During the CollPlant Biotechnologies Ltd. investor call, CEO Yehiel Tal and Deputy CEO Eran Rotem provided guidance centered on their regenerative medicine advancements, notably highlighting their proprietary photocurable dermal filler and regenerative breast implant programs. The dermal filler, aimed at a market valued at approximately $6.3 billion with a 10% CAGR, is currently in the preclinical phase, with plans to launch a clinical trial within two years. The regenerative breast implant program is progressing with preclinical testing of 250cc commercial-sized prototypes, showing promising results in tissue integration without complications. Financially, CollPlant reported a decrease in revenue from $11 million in 2023 to $515,000 in 2024, primarily due to a $10 million milestone payment from AbbVie in 2023. Despite a GAAP net loss of $16.6 million in 2024 compared to $7 million in 2023, the company maintains a stable cash position of $11.9 million as of December 31, 2024, not accounting for an additional $2 million payment from AbbVie, ensuring operational capability into the second quarter of 2026.

Collplant Holdings Financial Statement Overview

Summary
Financials are weak overall: highly volatile revenue, deep net losses in 2024–2025, and persistent negative operating/free cash flow indicating continued reliance on external funding. Offsetting factors are moderate leverage (debt-to-equity below 0.5) and some improvement in 2025 versus 2024 (higher revenue and a better gross margin), but the company remains far from break-even.
Income Statement
18
Very Negative
Balance Sheet
52
Neutral
Cash Flow
21
Negative
BreakdownDec 2025Dec 2024Mar 2024Dec 2022Dec 2021
Income Statement
Total Revenue2.37M515.00K10.96M299.00K15.64M
Gross Profit624.00K-2.15M7.87M-1.18M13.64M
EBITDA-10.57M-15.55M-5.91M-15.81M1.05M
Net Income-11.49M-16.61M-7.02M-16.93M237.00K
Balance Sheet
Total Assets10.79M18.71M34.13M37.77M51.22M
Cash, Cash Equivalents and Short-Term Investments5.95M11.91M26.67M29.65M43.30M
Total Debt2.85M3.08M3.16M2.91M3.61M
Total Liabilities4.70M5.25M5.79M5.49M6.10M
Stockholders Equity6.08M13.46M28.34M32.28M45.12M
Cash Flow
Free Cash Flow-9.45M-14.58M-3.72M-14.97M1.07M
Operating Cash Flow-9.42M-14.09M-2.76M-13.70M2.50M
Investing Cash Flow-27.00K-539.00K-1.16M28.92M-31.56M
Financing Cash Flow3.10M9.00K1.11M1.87M38.76M

Collplant Holdings Technical Analysis

Technical Analysis Sentiment
Negative
Last Price1.51
Price Trends
50DMA
0.57
Negative
100DMA
1.15
Negative
200DMA
1.74
Negative
Market Momentum
MACD
-0.10
Positive
RSI
34.62
Neutral
STOCH
30.29
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CLGN, the sentiment is Negative. The current price of 1.51 is above the 20-day moving average (MA) of 0.48, above the 50-day MA of 0.57, and below the 200-day MA of 1.74, indicating a bearish trend. The MACD of -0.10 indicates Positive momentum. The RSI at 34.62 is Neutral, neither overbought nor oversold. The STOCH value of 30.29 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CLGN.

Collplant Holdings Risk Analysis

Collplant Holdings disclosed 81 risk factors in its most recent earnings report. Collplant Holdings reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Collplant Holdings Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
$85.87M-2.64-291.42%54.52%
52
Neutral
$190.56M5.44-21.16%-100.00%67.23%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
49
Neutral
$33.20M-16.10322.94%
44
Neutral
$29.02M-1.76
42
Neutral
$5.52M-1.49-92.74%360.39%35.61%
42
Neutral
$16.39M-0.82-135.04%32.80%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CLGN
Collplant Holdings
0.41
-1.74
-80.93%
DARE
Daré Bioscience
2.34
-0.64
-21.48%
PASG
Passage Bio
4.97
-2.93
-37.09%
PYPD
PolyPid
4.44
1.65
59.14%
SABS
SAB Biotherapeutics
3.47
1.87
116.88%
NRSN
Neurosense Therapeutics Ltd.
0.90
-0.13
-13.01%

Collplant Holdings Corporate Events

CollPlant Resets Strategy After AbbVie Ends Filler Deal, Slashes Workforce by 50%
Apr 13, 2026
On April 9, 2026, Allergan Industrie SAS, an AbbVie company, notified CollPlant that it would terminate their February 2021 development agreement for an rhCollagen-based dermal and soft tissue filler, with the collaboration to end on June 8, 2026....
CollPlant Biotechnologies Details 2025 Results, Bioprinting Launch and Regenerative Implant Progress
Mar 26, 2026
On March 26, 2026, CollPlant Biotechnologies reported its 2025 financial results and outlined a broad corporate update highlighting progress in aesthetics, 3D bioprinting, and regenerative implants. The company emphasized a development milestone i...
CollPlant Biotechnologies Faces Nasdaq Bid-Price Deficiency, Granted Compliance Window
Mar 24, 2026
On March 23, 2026, CollPlant Biotechnologies received a Nasdaq notice that its ordinary shares had closed below $1.00 for 30 consecutive business days, putting the company out of compliance with Nasdaq Listing Rule 5550(a)(2). Under Nasdaq rules, ...
CollPlant Secures Korean Patent Allowance for Photocurable Dermal Filler Platform
Feb 26, 2026
On February 26, 2026, CollPlant Biotechnologies announced that the Korean Patent Office has allowed a patent application covering key aspects of its photocurable dermal filler technology for the aesthetic market. The patent, which runs through 203...
CollPlant Launches BioFlex rhCollagen Bioink Kit to Advance 3D Bioprinting
Feb 23, 2026
On February 23, 2026, Israel-based CollPlant announced BioFlex, a ready-to-print rhCollagen-based kit tailored for Digital Light Processing 3D bioprinting systems. The launch targets biopharma companies and academic institutions seeking animal-fre...
CollPlant Moves to Capture GLP-1-Driven Aesthetic Market With Photocurable rhCollagen Filler
Feb 17, 2026
On February 17, 2026, CollPlant announced it is strategically positioning its photocurable rhCollagen-based dermal filler platform to address facial volume loss linked to rapid weight reduction, including patients treated with GLP-1 weight-loss th...
CollPlant Biotechnologies Raises $2 Million in Registered Direct Offering with Concurrent Warrant Placement
Feb 6, 2026
On February 4, 2026, CollPlant Biotechnologies entered into a securities purchase agreement with institutional investors for a registered direct offering of 1,600,000 ordinary shares at $1.25 per share, alongside concurrent private placements of S...
CollPlant Biotechnologies Raises $2 Million in Registered Direct Offering to Support R&D
Feb 5, 2026
On February 5, 2026, CollPlant Biotechnologies announced it had entered into a definitive agreement for a $2.0 million registered direct offering, issuing 1,600,000 ordinary shares at $1.25 per share, alongside a concurrent private placement of un...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 17, 2026