Relief Therapeutics Holding Ag (CH:RLF)
:RLF
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RELIEF THERAPEUTICS Holding (RLF) AI Stock Analysis

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CH:RLF

RELIEF THERAPEUTICS Holding

(OTC:RLF)

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Neutral 44 (OpenAI - 4o)
Rating:44Neutral
Price Target:
CHF3.00
▲(14.07% Upside)
The overall stock score is primarily influenced by the company's financial performance, which shows potential but is hindered by ongoing losses and cash flow issues. Technical analysis provides a mixed outlook with some positive short-term trends, while valuation remains a concern due to negative earnings.

RELIEF THERAPEUTICS Holding (RLF) vs. iShares MSCI Switzerland ETF (EWL)

RELIEF THERAPEUTICS Holding Business Overview & Revenue Model

Company DescriptionRELIEF THERAPEUTICS Holding AG is a Swiss-based biopharmaceutical company focused on developing and commercializing novel, patent-protected products in the areas of rare metabolic and genetic disorders, as well as respiratory diseases. The company is committed to providing therapeutic relief and improving the quality of life for patients with serious medical conditions. RELIEF THERAPEUTICS operates in the healthcare and biotechnology sectors, leveraging its expertise in drug development and strategic partnerships to bring innovative treatments to market.
How the Company Makes MoneyRELIEF THERAPEUTICS makes money through the development and commercialization of its proprietary drug candidates. The company's primary revenue streams include licensing agreements, royalties from partnered products, and sales of its own therapeutic products. By engaging in strategic collaborations and partnerships with other biopharmaceutical companies, RELIEF THERAPEUTICS can expand its reach and enhance its product pipeline, which in turn contributes to its revenue. Additionally, the company may receive milestone payments related to the development and commercialization progress of its partnered drugs. These financial structures enable RELIEF THERAPEUTICS to sustain its operations and invest in further research and development activities.

RELIEF THERAPEUTICS Holding Financial Statement Overview

Summary
RELIEF THERAPEUTICS Holding shows revenue growth and a strong equity position, but ongoing losses and negative free cash flow highlight profitability and cash management challenges. The company has potential for improvement but faces significant operational hurdles.
Income Statement
35
Negative
The company shows some improvement in revenue, with a 39.5% growth from the previous year. Gross profit margin improved to 69.4%, but net profit remains negative, impacting the overall profitability. EBIT and EBITDA margins are negative, indicating operational challenges and inefficiencies.
Balance Sheet
45
Neutral
The debt-to-equity ratio is low at 0.06, suggesting limited leverage. However, the return on equity is negative due to continued net losses. The equity ratio is strong at 68.9%, indicating financial stability with a substantial equity base.
Cash Flow
30
Negative
Free cash flow remains negative, but it has improved compared to the previous year. The operating cash flow to net income ratio is less relevant due to negative net income. The company needs to improve cash generation to support operations and growth.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue4.05M8.42M6.03M6.08M3.32M0.00
Gross Profit-1.18M5.84M4.11M4.83M-8.59M0.00
EBITDA-18.22M-16.73M-108.04M-50.26M-32.69M-6.09M
Net Income-17.04M-17.12M-98.18M-50.79M-34.70M-7.83M
Balance Sheet
Total Assets47.99M53.22M76.39M188.80M251.62M78.05M
Cash, Cash Equivalents and Short-Term Investments12.50M15.08M14.56M19.24M44.76M43.15M
Total Debt1.90M2.14M2.96M4.34M4.26M891.00K
Total Liabilities15.35M16.56M24.16M43.38M70.09M11.00M
Stockholders Equity32.63M36.66M52.23M145.42M181.53M67.04M
Cash Flow
Free Cash Flow-3.43M-3.09M-18.06M-24.63M-49.42M-18.23M
Operating Cash Flow-3.40M-2.92M-17.61M-24.11M-35.71M-18.23M
Investing Cash Flow5.59M4.40M8.70M-8.02M-30.27M3.00M
Financing Cash Flow-303.00K-862.00K4.05M6.42M67.69M58.18M

RELIEF THERAPEUTICS Holding Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price2.63
Price Trends
50DMA
3.02
Negative
100DMA
2.74
Positive
200DMA
2.68
Positive
Market Momentum
MACD
>-0.01
Positive
RSI
48.30
Neutral
STOCH
14.19
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:RLF, the sentiment is Neutral. The current price of 2.63 is below the 20-day moving average (MA) of 2.95, below the 50-day MA of 3.02, and below the 200-day MA of 2.68, indicating a neutral trend. The MACD of >-0.01 indicates Positive momentum. The RSI at 48.30 is Neutral, neither overbought nor oversold. The STOCH value of 14.19 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for CH:RLF.

RELIEF THERAPEUTICS Holding Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
74
Outperform
$285.44M11.94744.64%
73
Outperform
CHF568.22M7.8058.51%
55
Neutral
$129.20M-1.97-49.86%-100.00%14.45%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
CHF790.83M-4.75228.54%63.37%
44
Neutral
CHF37.21M-40.91%-52.81%63.16%
41
Neutral
$140.58M-2.05-301.13%-56.85%-186.55%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:RLF
RELIEF THERAPEUTICS Holding
2.96
-3.64
-55.23%
CH:MOLN
Molecular Partners AG
3.54
-1.31
-27.01%
CH:BSLN
Basilea Pharmaceutica
46.90
6.20
15.23%
CH:IDIA
Idorsia Ltd
3.18
2.30
261.36%
CH:NWRN
Newron Pharmaceuticals SpA
15.26
7.65
100.53%
CH:SANN
Santhera Pharmaceuticals Holding
10.74
2.26
26.65%

RELIEF THERAPEUTICS Holding Corporate Events

Relief Therapeutics Plans Strategic Merger with NeuroX Group
Oct 24, 2025

Relief Therapeutics has announced an extraordinary general meeting to seek shareholder approval for a business combination with NeuroX Group SA. The meeting will address proposals including a capital increase and board member elections, aiming to rename the combined entity MindMaze Therapeutics Holding SA. This strategic move is expected to enhance Relief’s position in the biopharmaceutical industry by integrating NeuroX’s advanced neurotherapeutic technologies, potentially benefiting stakeholders through expanded treatment options and market reach.

The most recent analyst rating on (CH:RLF) stock is a Hold with a CHF2.50 price target. To see the full list of analyst forecasts on RELIEF THERAPEUTICS Holding stock, see the CH:RLF Stock Forecast page.

Relief Therapeutics and NeuroX Merge to Form AI-Driven Health Tech Leader
Oct 8, 2025

Relief Therapeutics and NeuroX have signed a definitive agreement to merge, creating a publicly listed AI-driven health tech company named MindMaze Therapeutics Holding SA. This merger positions the company as a leader in neurotherapeutic solutions, leveraging a robust commercialization network and a proprietary neuro-data engine for scalable precision medicine. The transaction, expected to close in December 2025, involves a significant equity exchange and aims to expand the company’s market presence and investor appeal, with plans to enhance visibility in the U.S. market.

The most recent analyst rating on (CH:RLF) stock is a Hold with a CHF3.00 price target. To see the full list of analyst forecasts on RELIEF THERAPEUTICS Holding stock, see the CH:RLF Stock Forecast page.

Relief Therapeutics Advances Pipeline and Explores AI-driven Expansion
Aug 14, 2025

Relief Therapeutics has released its 2025 half-year report, highlighting significant progress in its pipeline and corporate initiatives. The company has advanced its lead wound care candidate RLF-TD011 and is preparing for a pivotal trial of its next-generation liquid sapropterin formulation, RLF-OD032, for phenylketonuria. With cash reserves projected to last into late 2026, Relief is also exploring a business combination with NeuroX to establish an AI-driven health tech company.

Relief Therapeutics Advances 2025 Half-Year Report Publication
Aug 11, 2025

Relief Therapeutics has announced an advancement in the publication date of its 2025 half-year report, moving it forward to August 14, 2025, due to the early completion of the report. This report will include a shareholder update and interim financial statements, potentially impacting stakeholders by providing earlier insights into the company’s financial health and strategic direction.

Relief Therapeutics to Merge with NeuroX, Expanding AI-Driven Health Tech Platform
Jul 29, 2025

Relief Therapeutics has announced a proposed business combination with NeuroX, which recently acquired MindMaze, a leader in digital neurotherapeutics. This merger aims to create a publicly listed, AI-driven health tech company that integrates digital and pharmacological treatments for neurological diseases. The transaction is expected to close in Q4 2025, subject to customary conditions and approvals, and is anticipated to significantly enhance Relief’s market presence and growth potential.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Oct 28, 2025