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Molecular Partners AG (CH:MOLN)
:MOLN

Molecular Partners AG (MOLN) AI Stock Analysis

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CH:MOLN

Molecular Partners AG

(MOLN)

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Neutral 48 (OpenAI - 5.2)
Rating:48Neutral
Price Target:
CHF3.50
▼(-0.57% Downside)
The score is held down primarily by weak financial performance (zero TTM revenue, sizable losses, and ongoing cash burn) and a shrinking equity base, despite low leverage. Technicals are neutral-to-slightly positive (price above key longer-term averages with mildly positive MACD), but valuation remains pressured by negative earnings and no dividend support.
Positive Factors
Innovative Technology Platform
The proprietary DARPins platform allows for the development of targeted therapies, enhancing treatment efficacy and safety, which is a strong competitive advantage in the biotech industry.
Strategic Partnerships
Strategic partnerships with major pharmaceutical firms provide access to additional resources and expertise, which can accelerate the development and commercialization of new therapies.
Pipeline Advancement
The advancement of MP0712 into clinical trials represents progress in the pipeline, potentially leading to new treatment options and revenue streams if successful.
Negative Factors
Declining Revenues
Persistent revenue declines indicate challenges in monetizing the pipeline, which could affect long-term financial sustainability and operational funding.
Cash Flow Issues
Negative cash flow reflects ongoing cash burn, which can strain resources and necessitate additional financing, impacting long-term operational stability.
Profitability Concerns
Sustained losses and negative margins highlight profitability challenges, which could hinder the company's ability to reinvest in R&D and growth initiatives.

Molecular Partners AG (MOLN) vs. iShares MSCI Switzerland ETF (EWL)

Molecular Partners AG Business Overview & Revenue Model

Company DescriptionMolecular Partners AG operates as a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapeutic proteins. Its products candidates include Abicipar, a DARPin therapeutic candidate, which is in Phase III clinical trials for the treatment of neovascular wet age-related macular degeneration, as well as for diabetic macular edema; and MP0420, a multi-specific DARPin therapeutic candidate for the SARS-CoV-2 virus. The company develops MP0310, which is in Phase Ia clinical trials for immuno-oncology; MP0317, a tumor-localized immune agonist that activates immune cells in the tumor, which is in Phase I clinical trials; and MP0274 that is in Phase I clinical trials for HER2-positive cancers. It also develops MP0423 for treating COVID-19; MP0533, a CD3 T cell candidate for acute myeloid leukemia; and MP0250 for vascular endothelial growth factor, hepatocyte growth factor, and human serum albumin to increase half-life. Molecular Partners AG has agreements and collaboration with Novartis AG to develop, manufacture, and commercialize DARPin-conjugated radioligand therapies; Amgen SA; Allergan, Inc.; and discovery alliance with AbbVie Inc. in ophthalmology, as well as other third-party collaborators. The company was incorporated in 2004 and is headquartered in Schlieren, Switzerland.
How the Company Makes MoneyMolecular Partners generates revenue primarily through a combination of licensing agreements, collaborations with pharmaceutical companies, and potential milestone payments associated with the development of its therapeutic candidates. The company often enters into partnerships that allow it to co-develop drugs, which can provide upfront payments and royalties on future sales. Additionally, if its drug candidates receive regulatory approval, the company can earn significant milestone payments from partners. The monetization of its DARPins technology through these collaborations is a critical aspect of its revenue model, alongside potential future product sales.

Molecular Partners AG Earnings Call Summary

Earnings Call Date:Mar 06, 2025
(Q4-2024)
|
% Change Since: |
Next Earnings Date:Mar 12, 2026
Earnings Call Sentiment Positive
Molecular Partners demonstrated significant progress in advancing their pipeline, particularly with the radio DARPin franchise and T cell engager 533, while maintaining a strong financial position. However, the discontinuation of the Novartis collaboration and resulting revenue impact were notable drawbacks.
Q4-2024 Updates
Positive Updates
Successful Execution of 2024 Program Goals
Molecular Partners advanced their radio DARPin franchise with the lead compound DLL3 targeting 712 passing all IND-enabling studies, ready for clinical trials. They selected mesothelin as a new target and expanded their collaboration with Orano Med, securing 10 slots for Lead-212 isotope.
Positive Financial Health
The company ended 2024 with a cash balance of CHF 149 million, which supports operations into 2027. They raised CHF 20 million through financing, maintaining a solid financial base with no debt.
Encouraging Clinical Results and Pipeline Progression
The T cell engager 533 showed significant improvements in efficacy with new dosing strategies, resulting in 3 complete responses out of 8 patients treated past day 12.
Negative Updates
Novartis Collaboration Setback
The collaboration with Novartis was not continued as the targets did not progress as expected. This decision was mutual and based on strategic interests.
Revenue Decline from Novartis Collaboration
Revenue decreased as 2024 recognized the last part of the upfront payment from the Novartis collaboration, with no further revenue expected from this source.
Company Guidance
During the Molecular Partners Fourth Quarter and Full Year 2024 Results Call, several notable metrics and guidance were provided. For the fiscal year 2024, the company reported revenues of CHF 5 million, exclusively from the Novartis collaboration. Operating expenses were CHF 66 million, within the guidance range of CHF 65 million to CHF 70 million, with 74% allocated to R&D. The net financial result benefited from high interest rates, contributing to an end-of-year cash balance of CHF 149 million, down from CHF 187 million the previous year, resulting in a cash burn of CHF 54 million. Looking ahead to 2025, Molecular Partners anticipates operating expenses between CHF 55 million and CHF 65 million, excluding potential partnership payments. The company is focused on advancing its radio DARPin programs, particularly MP0712, with expectations to start clinical trials and provide initial imaging data by the end of the year, while also progressing with its T cell engager program, MP0533, in AML, with new dosing amendments and outcomes expected by year-end.

Molecular Partners AG Financial Statement Overview

Summary
Overall financials are weak: TTM revenue is zero with a large net loss (~-60M) and negative operating/free cash flow (~-53M/~-54M), indicating continued cash burn. The balance sheet is a relative positive with very low leverage (debt-to-equity ~1.6%), but equity has fallen sharply (from ~235M in 2022 to ~96M TTM), reflecting ongoing losses and shrinking capital base.
Income Statement
18
Very Negative
Profitability is weak in TTM (Trailing-Twelve-Months), with revenue at zero and a large net loss (about -60M), indicating heavy ongoing spend without offsetting product/partner income. Results have also deteriorated versus 2022, when the company posted very strong revenue (~190M) and substantial profits, highlighting high volatility and dependence on non-recurring or uneven revenue sources. The main positive is that losses have been relatively consistent in the ~54M–64M range in most years outside 2022, which suggests a steady cost base, but the lack of revenue traction in the most recent period is a major concern.
Balance Sheet
62
Positive
The balance sheet is a relative strength: leverage is very low (debt-to-equity ~1.6% in TTM (Trailing-Twelve-Months)), providing flexibility and lowering refinancing risk. However, equity has declined meaningfully from 2022 to TTM (from ~235M to ~96M), consistent with sustained losses and cash burn, and returns on equity are sharply negative in recent periods. Overall, the company is not over-levered, but the capital base is shrinking.
Cash Flow
24
Negative
Cash generation is weak, with negative operating cash flow in TTM (Trailing-Twelve-Months) (about -53M) and negative free cash flow (about -54M), implying continued cash burn to fund operations. Cash burn is broadly similar to 2023–2024 levels and improved versus 2021 (when operating cash outflow was ~-91M), but it remains materially negative. A key risk is sustainability: without a rebound in revenue or external funding, ongoing negative free cash flow can further pressure the balance sheet over time.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.004.97M7.04M189.56M9.33M9.34M
Gross Profit-8.88M-42.53M-40.81M138.81M-46.39M-46.73M
EBITDA-58.01M-51.63M-59.52M119.00M-60.66M-59.58M
Net Income-60.24M-54.04M-61.98M117.85M-63.78M-62.76M
Balance Sheet
Total Assets112.15M158.53M198.35M262.26M172.67M187.55M
Cash, Cash Equivalents and Short-Term Investments104.52M149.44M186.89M249.14M132.81M173.72M
Total Debt1.53M2.44M3.65M4.85M6.04M7.22M
Total Liabilities16.62M16.89M21.92M27.09M65.38M80.33M
Stockholders Equity95.53M141.64M176.43M235.17M107.29M107.22M
Cash Flow
Free Cash Flow-54.01M-59.97M-59.81M117.15M-92.26M-30.67M
Operating Cash Flow-53.30M-59.25M-59.01M118.57M-90.95M-28.98M
Investing Cash Flow56.10M40.49M44.64M-101.12M-22.24M-21.75M
Financing Cash Flow14.45M14.43M-1.17M-1.57M50.58M113.20M

Molecular Partners AG Technical Analysis

Technical Analysis Sentiment
Positive
Last Price3.52
Price Trends
50DMA
3.30
Positive
100DMA
3.14
Positive
200DMA
3.12
Positive
Market Momentum
MACD
0.02
Negative
RSI
59.89
Neutral
STOCH
65.49
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:MOLN, the sentiment is Positive. The current price of 3.52 is above the 20-day moving average (MA) of 3.25, above the 50-day MA of 3.30, and above the 200-day MA of 3.12, indicating a bullish trend. The MACD of 0.02 indicates Negative momentum. The RSI at 59.89 is Neutral, neither overbought nor oversold. The STOCH value of 65.49 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CH:MOLN.

Molecular Partners AG Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
67
Neutral
CHF395.49M16.50744.64%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$141.92M-2.17-49.86%-100.00%14.45%
48
Neutral
CHF180.10M-2.52-301.13%-56.85%-186.55%
46
Neutral
CHF929.20M-5.41229.23%63.47%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:MOLN
Molecular Partners AG
3.52
-0.98
-21.80%
CH:IDIA
Idorsia Ltd
3.62
2.92
420.14%
CH:NWRN
Newron Pharmaceuticals SpA
19.76
10.01
102.67%
CH:SANN
Santhera Pharmaceuticals Holding
12.94
-3.92
-23.25%
CH:XLS
Xlife Sciences Ltd.
21.00
-1.00
-4.55%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 13, 2026