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Santhera Pharmaceuticals Holding (CH:SANN)
:SANN
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Santhera Pharmaceuticals Holding (SANN) AI Stock Analysis

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CH:SANN

Santhera Pharmaceuticals Holding

(OTC:SANN)

Rating:44Neutral
Price Target:
CHF12.50
▼(-12.10% Downside)
Santhera Pharmaceuticals' overall stock score is primarily impacted by its weak financial performance, characterized by high leverage, negative profitability, and cash flow issues. Technical analysis provides some positive signals, but the valuation remains a concern due to ongoing losses. The absence of earnings call data and corporate events limits additional insights.
Positive Factors
Financial Health
Santhera's balance sheet appears healthy with potential runway through to cash flow breakeven, supported by expected top-line revenue growth.
International Expansion
Multiple recent distribution agreements broaden vamorolone footprint internationally.
Negative Factors
Market Risks
Risks include, but are not limited to: setbacks with vamorolone in areas beyond DMD, partnership risks, slower-than-projected market uptake for vamorolone in the U.S. and EU, inability to optimize vamorolone's value in other countries and territories, currency risks due to a decline in the relative value of the U.S. dollar, and possible medium- to long-term dilution risk.

Santhera Pharmaceuticals Holding (SANN) vs. iShares MSCI Switzerland ETF (EWL)

Santhera Pharmaceuticals Holding Business Overview & Revenue Model

Company DescriptionSanthera Pharmaceuticals Holding AG (SANN) is a Swiss biopharmaceutical company focused on developing and commercializing innovative therapies for the treatment of rare diseases, primarily neuromuscular disorders. The company is committed to addressing unmet medical needs by leveraging its expertise in drug development and its strategic partnerships. Santhera's core products include therapies for conditions such as Duchenne muscular dystrophy and other rare diseases, utilizing both proprietary and licensed technologies to enhance patient outcomes.
How the Company Makes MoneySanthera Pharmaceuticals generates revenue primarily through the commercialization of its pharmaceutical products. Key revenue streams include sales of approved drugs, potential royalties from partnered products, and milestone payments from collaborations with other pharmaceutical companies. The company actively seeks partnerships to expand its market reach and enhance its product pipeline. Additionally, Santhera may receive funding through grants and subsidies aimed at supporting research and development in rare diseases, which contribute to its financial sustainability.

Santhera Pharmaceuticals Holding Financial Statement Overview

Summary
Santhera Pharmaceuticals faces significant financial challenges with volatile revenue, negative profitability, high leverage, and cash flow difficulties. Despite a strong revenue year in 2023, the company needs operational improvements and financial restructuring for stability.
Income Statement
45
Neutral
Santhera Pharmaceuticals has shown a volatile revenue trend with a significant drop in 2024 compared to 2023. The company struggles with profitability as indicated by negative EBIT and net income margins. However, past revenue growth was notable in 2023, suggesting potential for recovery if operational issues are addressed.
Balance Sheet
30
Negative
The company's balance sheet shows high leverage with a debt-to-equity ratio exceeding 1, indicating reliance on debt financing. The equity ratio is low, reflecting weak equity position. Persistent negative stockholders' equity in some years raises concerns about financial stability.
Cash Flow
40
Negative
Cash flow from operations has been negative in recent years, indicating challenges in generating cash internally. Positive financing cash flows highlight reliance on external funding. Free cash flow turned negative, suggesting cash management issues despite periods of positive operating cash flow in the past.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue39.12M103.41M7.47M-1.59M15.01M
Gross Profit22.96M100.18M3.88M-5.36M4.58M
EBITDA-15.89M79.17M-46.78M-34.57M-53.43M
Net Income-41.97M54.78M-71.08M-55.53M-67.66M
Balance Sheet
Total Assets152.49M109.63M63.73M91.12M88.69M
Cash, Cash Equivalents and Short-Term Investments40.92M30.37M1.35M21.21M12.41M
Total Debt40.62M21.55M44.44M42.98M71.17M
Total Liabilities124.79M49.69M107.41M89.79M95.04M
Stockholders Equity27.70M59.94M-43.69M1.33M-6.35M
Cash Flow
Free Cash Flow-35.68M23.53M-33.80M-37.37M-43.54M
Operating Cash Flow-35.53M47.27M-29.84M-37.36M-43.51M
Investing Cash Flow-61.00K-18.04M-3.93M69.00K1.56M
Financing Cash Flow46.08M-171.00K13.99M46.02M23.15M

Santhera Pharmaceuticals Holding Technical Analysis

Technical Analysis Sentiment
Positive
Last Price14.22
Price Trends
50DMA
13.45
Positive
100DMA
13.32
Positive
200DMA
13.41
Positive
Market Momentum
MACD
0.08
Positive
RSI
57.78
Neutral
STOCH
52.90
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:SANN, the sentiment is Positive. The current price of 14.22 is above the 20-day moving average (MA) of 13.80, above the 50-day MA of 13.45, and above the 200-day MA of 13.41, indicating a bullish trend. The MACD of 0.08 indicates Positive momentum. The RSI at 57.78 is Neutral, neither overbought nor oversold. The STOCH value of 52.90 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for CH:SANN.

Santhera Pharmaceuticals Holding Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
65
Neutral
CHF570.66M7.84
58.51%
51
Neutral
$7.95B-0.38-43.43%2.22%22.30%-1.83%
51
Neutral
CHF663.31M
67.18%-480.10%
44
Neutral
$184.59M2.58-93.91%-62.17%-166.33%
$146.75M-48.90%
$234.55M11.40
CHF119.97M3.58
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:SANN
Santhera Pharmaceuticals Holding
14.24
4.48
45.90%
MLLCF
Molecular Partners AG
4.22
-1.67
-28.35%
CH:BSLN
Basilea Pharmaceutica
46.50
1.45
3.22%
CH:IDIA
Idorsia Ltd
3.07
1.34
77.46%
NWPHF
Newron Pharmaceuticals SpA
9.36
0.00
0.00%
CH:XLS
Xlife Sciences Ltd.
21.50
-4.80
-18.25%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Aug 14, 2025