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Santhera Pharmaceuticals Holding (CH:SANN)
:SANN
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Santhera Pharmaceuticals Holding (SANN) AI Stock Analysis

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CH:SANN

Santhera Pharmaceuticals Holding

(OTC:SANN)

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Underperform 38 (OpenAI - 4o)
Rating:38Underperform
Price Target:
CHF11.00
▲(2.04% Upside)
Santhera Pharmaceuticals' overall stock score is primarily impacted by its weak financial performance and poor valuation metrics. Technical analysis indicates bearish momentum, further weighing down the score. The company needs significant operational and financial restructuring to improve its outlook.
Positive Factors
Strategic Partnerships
Strategic partnerships can provide Santhera with access to new markets and resources, enhancing its product offerings and potentially improving revenue streams over time.
Focus on Rare Diseases
By targeting rare diseases, Santhera can benefit from niche markets with less competition and potentially higher pricing power, supporting long-term revenue growth.
Revenue from Grants and Subsidies
Grants and subsidies provide non-dilutive funding that can support R&D activities, reducing financial strain and fostering innovation in developing new therapies.
Negative Factors
High Leverage
High leverage indicates reliance on debt financing, which can increase financial risk and limit the company's ability to invest in growth opportunities.
Negative Cash Flow
Negative cash flow from operations suggests challenges in generating sufficient cash internally, potentially leading to increased reliance on external funding and impacting financial stability.
Volatile Revenue
Volatile revenue trends can create uncertainty and hinder long-term planning, making it difficult for the company to maintain consistent growth and profitability.

Santhera Pharmaceuticals Holding (SANN) vs. iShares MSCI Switzerland ETF (EWL)

Santhera Pharmaceuticals Holding Business Overview & Revenue Model

Company DescriptionSanthera Pharmaceuticals Holding AG, a specialty pharmaceutical company, together with its subsidiaries, develops and commercializes medicines for rare neuromuscular and pulmonary diseases with high unmet medical need in the European Union and internationally. The company's lead pipeline candidate includes vamorolone, which is being developed as treatments for Duchenne muscular dystrophy (DMD). Its clinical stage pipeline also comprises lonodelestat (POL6014) to treat cystic fibrosis and other neutrophilic pulmonary diseases, as well as omigapil that treats congenital muscular dystrophies. The company also out-licenses outside North America and France rights to its approved product, Raxone (idebenone), for the treatment of Leber's hereditary optic neuropathy. Santhera Pharmaceuticals Holding AG was founded in 2004 and is headquartered in Pratteln, Switzerland.
How the Company Makes MoneySanthera Pharmaceuticals generates revenue primarily through the commercialization of its pharmaceutical products. Key revenue streams include sales of approved drugs, potential royalties from partnered products, and milestone payments from collaborations with other pharmaceutical companies. The company actively seeks partnerships to expand its market reach and enhance its product pipeline. Additionally, Santhera may receive funding through grants and subsidies aimed at supporting research and development in rare diseases, which contribute to its financial sustainability.

Santhera Pharmaceuticals Holding Financial Statement Overview

Summary
Santhera Pharmaceuticals faces significant financial challenges with volatile revenue, negative profitability, high leverage, and cash flow difficulties. Despite a strong revenue year in 2023, the company needs operational improvements and financial restructuring for stability.
Income Statement
45
Neutral
Santhera Pharmaceuticals has shown a volatile revenue trend with a significant drop in 2024 compared to 2023. The company struggles with profitability as indicated by negative EBIT and net income margins. However, past revenue growth was notable in 2023, suggesting potential for recovery if operational issues are addressed.
Balance Sheet
30
Negative
The company's balance sheet shows high leverage with a debt-to-equity ratio exceeding 1, indicating reliance on debt financing. The equity ratio is low, reflecting weak equity position. Persistent negative stockholders' equity in some years raises concerns about financial stability.
Cash Flow
40
Negative
Cash flow from operations has been negative in recent years, indicating challenges in generating cash internally. Positive financing cash flows highlight reliance on external funding. Free cash flow turned negative, suggesting cash management issues despite periods of positive operating cash flow in the past.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue39.12M103.41M7.47M-1.59M15.01M
Gross Profit22.96M100.18M3.88M-5.36M4.58M
EBITDA-15.89M79.17M-46.78M-34.57M-53.43M
Net Income-41.97M54.78M-71.08M-55.53M-67.66M
Balance Sheet
Total Assets152.49M109.63M63.73M91.12M88.69M
Cash, Cash Equivalents and Short-Term Investments40.92M30.37M1.35M21.21M12.41M
Total Debt40.62M21.55M44.44M42.98M71.17M
Total Liabilities124.79M49.69M107.41M89.79M95.04M
Stockholders Equity27.70M59.94M-43.69M1.33M-6.35M
Cash Flow
Free Cash Flow-35.68M23.53M-33.80M-37.37M-43.54M
Operating Cash Flow-35.53M47.27M-29.84M-37.36M-43.51M
Investing Cash Flow-61.00K-18.04M-3.93M69.00K1.56M
Financing Cash Flow46.08M-171.00K13.99M46.02M23.15M

Santhera Pharmaceuticals Holding Technical Analysis

Technical Analysis Sentiment
Negative
Last Price10.78
Price Trends
50DMA
13.70
Negative
100DMA
13.14
Negative
200DMA
13.81
Negative
Market Momentum
MACD
-0.83
Positive
RSI
26.95
Positive
STOCH
9.81
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:SANN, the sentiment is Negative. The current price of 10.78 is below the 20-day moving average (MA) of 13.28, below the 50-day MA of 13.70, and below the 200-day MA of 13.81, indicating a bearish trend. The MACD of -0.83 indicates Positive momentum. The RSI at 26.95 is Positive, neither overbought nor oversold. The STOCH value of 9.81 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for CH:SANN.

Santhera Pharmaceuticals Holding Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
69
Neutral
CHF209.19M8.751086.63%744.64%
68
Neutral
CHF550.56M7.5695.80%58.51%
51
Neutral
CHF839.50M-4.9821.76%67.18%-480.10%
46
Neutral
CHF112.85M-1.55-38.16%-91.34%-2.84%
38
Underperform
$136.89M2.58-301.13%-56.85%-186.55%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:SANN
Santhera Pharmaceuticals Holding
10.78
1.61
17.56%
CH:MOLN
Molecular Partners AG
2.82
-1.19
-29.80%
CH:BSLN
Basilea Pharmaceutica
46.15
0.55
1.21%
CH:IDIA
Idorsia Ltd
3.82
2.29
149.67%
CH:NWRN
Newron Pharmaceuticals SpA
10.82
3.12
40.52%
CH:XLS
Xlife Sciences Ltd.
20.00
-9.20
-31.51%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Sep 25, 2025