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Basilea Pharmaceutica (CH:BSLN)
:BSLN

Basilea Pharmaceutica (BSLN) AI Stock Analysis

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Basilea Pharmaceutica

(BSLN)

Rating:75Outperform
Price Target:
CHF55.00
▲(14.46%Upside)
Basilea Pharmaceutica's strong financial performance and low valuation are significant positives. The earnings call further supports a positive outlook with growth in key products and strategic funding. Despite bullish technical indicators, the stock is in overbought territory, posing potential short-term risks. Overall, the company is on a promising trajectory, but high liabilities and technical risks should be monitored.
Positive Factors
Market Expansion
Ceftobiprole was included in the National Reimbursement Drug List (NRDL), making it eligible for reimbursement under the Chinese national basic medical insurance program.
Product Sales Performance
Cresemba sales reach another pre-defined threshold, triggering a milestone payment.
Regulatory Approvals
The FDA approved Zevtera for three specific indications; it is the only FDA-approved methicillin-resistant Staphylococcus aureus (MRSA) cephalosporin antibiotic for treating adult patients with S. aureus bloodstream infections (bacteremia) and endocarditis.
Negative Factors
Market Penetration Challenges
Risks include potential challenges in market penetration for ceftobiprole in the U.S. and setbacks with clinical-stage candidates like fosmanogepix.
Partnership Optimization Risks
Risks include inability by Basilea's partners to optimize the value of isavuconazole and ceftobiprole globally.

Basilea Pharmaceutica (BSLN) vs. iShares MSCI Switzerland ETF (EWL)

Basilea Pharmaceutica Business Overview & Revenue Model

Company DescriptionBasilea Pharmaceutica (BSLN) is a biopharmaceutical company focused on the research, development, and commercialization of innovative pharmaceutical products to address the medical needs in the areas of oncology and infectious diseases. Based in Switzerland, Basilea's core products include a portfolio of treatments for bacterial infections and antifungal agents, as well as targeted cancer therapies. The company is committed to improving patient outcomes through the development of novel medicines that address drug resistance and provide new therapeutic options.
How the Company Makes MoneyBasilea Pharmaceutica generates revenue primarily through the sale of its pharmaceutical products, which include Cresemba (an antifungal) and Zevtera (an antibiotic), to healthcare providers and institutions. The company also earns income through licensing agreements and collaborations with other pharmaceutical companies, who may pay royalties, milestone payments, or upfront fees to gain access to Basilea's proprietary compounds and technologies. Additionally, Basilea engages in strategic partnerships to expand its market reach and leverage its R&D capabilities, further contributing to its revenue streams. Key factors influencing earnings include the successful commercialization of its product pipeline, regulatory approvals, and the ability to secure and maintain partnerships within the pharmaceutical industry.

Basilea Pharmaceutica Earnings Call Summary

Earnings Call Date:Feb 18, 2025
(Q4-2024)
|
% Change Since: 17.63%|
Next Earnings Date:Aug 19, 2025
Earnings Call Sentiment Positive
The earnings call reflected a strong financial performance with substantial growth in key products like Cresemba and new approvals for Zevtera. The company secured significant non-dilutive funding and expanded its pipeline, although it faced challenges with the tonabacase development. Overall, the positive aspects significantly outweigh the few lowlights.
Q4-2024 Updates
Positive Updates
Strong Financial Performance
Basilea reported a tripling of operating profit and a five-fold increase in operating cash flow for 2024. Total revenue grew by 32% to CHF208.5 million, with Cresemba and Zevtera-related revenue increasing by 30% year-on-year.
Cresemba Sales Growth
Cresemba achieved a 20% increase in global in-market sales, totaling over $0.5 billion for the 12-month period ending September 2024. It remains the largest branded antifungal for invasive fungal infections worldwide.
Zevtera U.S. Approval
Zevtera received FDA approval for a broad range of indications in the U.S., with Innoviva Specialty Therapeutics as the commercialization partner.
Non-Dilutive R&D Funding
Basilea secured significant non-dilutive funding, including up to $268 million from BARDA and additional grants from CARB-X to support antifungal and antibiotic development.
Pipeline Expansion
Significant progress was made in expanding the pipeline, including the initiation of Phase 3 studies for fosmanogepix, development of BAL2420, and acquisition of LptA inhibitors.
Negative Updates
Tonabacase Development Halt
After a thorough preclinical evaluation, Basilea decided not to pursue the development of tonabacase, a bactericidal endolysin, as it did not meet the company's stringent criteria.
Product Supply Decrease to Pfizer
A decrease in product supply to Pfizer was announced, resulting from the successful transfer of the majority of manufacturing responsibilities to the partner.
Company Guidance
During the Basilea Pharmaceutica Full-Year Results 2024 Conference Call, the company provided guidance on several key metrics. Cresemba, their leading antifungal product, saw a 20% increase in global in-market sales, surpassing $0.5 billion for the year ending September 2024. This growth contributed to a 30% year-on-year increase in Cresemba and Zevtera-related revenue. Basilea reported a tripling of operating profit and a five-fold increase in operating cash flow compared to 2023, ending the year with a strong cash position and net cash. Total revenue for 2024 grew by 32% to CHF208.5 million, with Cresemba and Zevtera-related revenue reaching CHF194.9 million. The company achieved a net profit of CHF77.6 million, supported by a CHF17.3 million deferred tax asset gain. For 2025, Basilea expects total revenue to grow to approximately CHF220 million, supported by a 14% increase in royalty income and reimbursements from BARDA and CARB-X. Operating profit is anticipated to remain high at around CHF62 million, despite an expected 14% increase in R&D expenses. The company plans to maintain its focus on expanding its pipeline in antifungals and antibacterials while leveraging non-dilutive funding to support its research and development efforts.

Basilea Pharmaceutica Financial Statement Overview

Summary
Basilea Pharmaceutica has demonstrated strong revenue growth and improved profitability with a significant net profit margin increase in 2024. The cash flow is robust, with a substantial free cash flow increase. However, balance sheet concerns persist due to high liabilities.
Income Statement
72
Positive
Basilea Pharmaceutica has shown strong revenue growth from 2023 to 2024 with an increase of 32.3%. The gross profit margin decreased from 2023 to 2024 due to a decline in gross profit. However, the net profit margin improved significantly to 37.2% in 2024, indicating better profitability. The EBIT and EBITDA margins also saw significant improvements, indicating enhanced operational efficiency.
Balance Sheet
58
Neutral
The company has improved its balance sheet with positive stockholders' equity in 2024, moving from negative in previous years. The debt-to-equity ratio has improved as equity turned positive, and the equity ratio at 31.4% indicates a stronger financial position. However, high total liabilities relative to assets remain a concern.
Cash Flow
80
Positive
The cash flow statement shows a strong free cash flow growth of 449.6% from 2023 to 2024, indicating robust cash generation. The operating cash flow to net income ratio is healthy, supporting the company's profitability and cash generation capabilities. The free cash flow to net income ratio is also strong, reflecting efficient cash management.
BreakdownDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue208.54M157.63M147.76M148.12M127.63M
Gross Profit169.86M130.84M120.96M124.05M103.58M
EBITDA63.13M23.18M26.21M6.72M-2.24M
Net Income77.59M10.45M12.15M-6.83M-14.72M
Balance Sheet
Total Assets257.76M173.29M220.85M247.27M229.79M
Cash, Cash Equivalents and Short-Term Investments120.71M59.90M86.57M149.95M167.28M
Total Debt111.67M128.61M187.14M218.96M242.32M
Total Liabilities176.76M183.29M241.56M305.87M331.84M
Stockholders Equity81.00M-10.00M-20.71M-58.61M-102.05M
Cash Flow
Free Cash Flow72.65M13.21M3.75M-32.88M-56.40M
Operating Cash Flow74.36M14.24M7.06M-32.02M-54.13M
Investing Cash Flow-1.01M-1.03M91.65M3.58M-34.96M
Financing Cash Flow-13.16M-57.30M-45.25M16.64M45.07M

Basilea Pharmaceutica Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price48.05
Price Trends
50DMA
45.77
Positive
100DMA
45.03
Positive
200DMA
43.80
Positive
Market Momentum
MACD
0.70
Positive
RSI
47.80
Neutral
STOCH
5.74
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For CH:BSLN, the sentiment is Neutral. The current price of 48.05 is below the 20-day moving average (MA) of 48.97, above the 50-day MA of 45.77, and above the 200-day MA of 43.80, indicating a neutral trend. The MACD of 0.70 indicates Positive momentum. The RSI at 47.80 is Neutral, neither overbought nor oversold. The STOCH value of 5.74 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for CH:BSLN.

Basilea Pharmaceutica Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
75
Outperform
CHF585.04M7.50
32.30%631.04%
64
Neutral
$1.04B-6.44%125.11%69.27%
60
Neutral
CHF136.53M9.69
450.19%
53
Neutral
CHF441.51M
11.61%-356.20%
51
Neutral
$7.41B0.36-61.88%2.34%16.99%1.69%
47
Neutral
$124.96M-40.40%-66.82%4.14%
39
Underperform
CHF154.00M2.58-93.91%-62.17%-166.33%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
CH:BSLN
Basilea Pharmaceutica
47.60
8.10
20.51%
CH:MOLN
Molecular Partners AG
2.96
-3.61
-54.95%
CH:IDIA
Idorsia Ltd
2.02
-0.08
-3.81%
CH:NWRN
Newron Pharmaceuticals SpA
6.84
-2.00
-22.62%
CH:SANN
Santhera Pharmaceuticals Holding
11.98
3.47
40.78%
CH:KURN
Kuros Biosciences
28.40
16.18
132.41%
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jun 06, 2025