Strong Fourth Quarter and Full Year Performance
Closed 2024 with strong fourth quarter performance, reflecting another quarter of double-digit percentage increase for the growth portfolio. Full year growth portfolio delivered double-digit revenue growth led by BREYANZI, Krazati, Reblozyl, and Opdivo.
Commercial and R&D Milestones
Reestablished presence in neuroscience with the U.S. approval and launch of Cobenfy, the first novel mechanism for schizophrenia treatment in decades. U.S. approval of Opdivo Quvantic in late December to extend immuno-oncology reach.
Operational Excellence and Financial Discipline
Achieved most of the targeted $1.5 billion in savings, with significant reallocation towards high potential growth opportunities. Identified an additional $2 billion in savings to be realized by the end of 2027.
Accelerated R&D Productivity
Completed enrollment in the ODYSSEY study 6 months earlier than expected. Advanced timelines for clinical data readouts, including Cobenfy's ADEPT 2 study in Alzheimer's disease psychosis.
Promising Data and Pipeline
Multiple important registrational catalysts expected in 2025, including Milvexian in acute coronary syndrome and secondary stroke prevention, and Arlocell GPRC5D CAR-T in multiple myeloma.