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BioAtla (BCAB)
NASDAQ:BCAB
US Market

BioAtla (BCAB) AI Stock Analysis

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BioAtla

(NASDAQ:BCAB)

Rating:35Underperform
Price Target:
BioAtla's stock faces significant challenges, primarily due to its financial position, characterized by a lack of revenue and high cash burn. Despite promising clinical progress and strategic efforts to manage cash, the company's valuation and technical indicators reflect a bearish outlook. The overall score reflects these substantial risks, with some potential upside from clinical developments.
Positive Factors
Cost management
BioAtla has reduced its workforce by over 30%, which increases its cash runway into the first half of 2026.
Efficacy of pipeline drugs
The AXL-ADC program demonstrates a compelling OS signal in NSCLC and sarcoma, potentially providing pan-KRAS therapy in late line NSCLC.
Negative Factors
Financial performance
BioAtla reported no revenue and a net loss of $14.9M for the fourth quarter.
Pipeline development uncertainties
There are uncertainties regarding BioAtla’s pipeline development and a near-term financial overhang.

BioAtla (BCAB) vs. SPDR S&P 500 ETF (SPY)

BioAtla Business Overview & Revenue Model

Company DescriptionBioAtla, Inc. (BCAB) is a biotechnology company focused on the development of Conditionally Active Biologic (CAB) antibody therapeutics. The company operates primarily in the biopharmaceutical sector, leveraging its proprietary CAB technology to create therapies that are activated under specific physiological conditions, enhancing safety and efficacy. BioAtla's core products include a pipeline of CAB antibody candidates aimed at treating various cancers, with a focus on improving patient outcomes through innovative therapeutic solutions.
How the Company Makes MoneyBioAtla makes money primarily through the development and commercialization of its CAB antibody therapeutics. The company's revenue model includes partnerships and collaborations with other pharmaceutical companies for the development and potential commercialization of its drug candidates. These partnerships often involve upfront payments, milestone payments upon achieving certain development or regulatory goals, and potential royalties on future sales of approved therapies. BioAtla may also generate revenue through licensing agreements that allow other companies to use its proprietary technology in their therapeutic development. Additionally, BioAtla may seek funding through public and private investments to support its research and development activities.

BioAtla Earnings Call Summary

Earnings Call Date:May 06, 2025
(Q1-2025)
|
% Change Since: -20.83%|
Next Earnings Date:Aug 07, 2025
Earnings Call Sentiment Positive
The earnings call reflects a positive overall sentiment with notable achievements in clinical trials and substantial financial improvements despite some challenges such as workforce reduction and decreased cash reserves.
Q1-2025 Updates
Positive Updates
Tumor Reduction in EpCAM and CD3 T Cell Engager Study
Multiple patients in the Phase 1 dose escalation study showed tumor reduction and tolerated the therapy well, with some patients being on therapy for months without progression.
Exceptional Survival with Mec-V
The Mec-V study showed a 59% 2-year survival rate in mKRAS non-small cell lung cancer patients, significantly higher than the less than 20% seen with standard care.
Positive Results in Soft Tissue Sarcoma
Mec-V demonstrated a 73% 1-year landmark survival rate across several subtypes of soft tissue sarcoma.
Compelling Data in HPV Positive Head and Neck Cancer
The CAB-ROR2-ADC, Oz-V, showed a 100% disease control rate and a 45% overall response rate in heavily pretreated metastatic HPV positive head and neck cancer patients.
Strong Financial Management
The company reported a reduced net loss of $15.3 million, down from $23.2 million in the previous year, with significant cost reductions expected to extend runway until 2026.
Negative Updates
Workforce Reduction
A workforce reduction resulted in a $0.5 million charge, reflecting the company's restructuring efforts.
Decreased Cash Reserves
Cash and cash equivalents decreased from $49 million to $32.4 million between December 2024 and March 2025.
Dependency on Partnerships
The company's future funding and operations heavily rely on forming new strategic partnerships.
Company Guidance
During BioAtla's Q1 2025 earnings call, the company provided guidance on several key metrics and developments. BioAtla is progressing well with its Phase 1 dose escalation study of the dual conditionally binding EpCAM and CD3 T cell engager and has not yet reached the maximally tolerated dose. Three patients in the 100 micrograms cohort cleared the dose-limiting toxicity period, and the first three patients in the 300 micrograms cohort have been dosed, with a clinical data readout expected in mid-2025. For the CAB-AXL-ADC Mec-V, the company reported a 2-year landmark survival rate of 59% among mKRAS non-small cell lung cancer patients, which significantly exceeds the less than 20% survival rate observed in previous studies with standard care agents. Mec-V also showed a 1-year landmark survival of 73% in various subtypes of soft tissue sarcoma. Furthermore, the CAB-ROR2-ADC, Oz-V, demonstrated a 100% disease control rate and a 45% overall response rate in metastatic HPV-positive head and neck cancer patients. BioAtla anticipates leveraging its Fast Track Designation for further FDA discussions. Financially, the company reported R&D expenses of $12.4 million, a decrease from $18.9 million in Q1 2024, and a net loss of $15.3 million, down from $23.2 million in the prior year. Cash and cash equivalents stood at $32.4 million as of March 31, 2025, with expectations to fund operations and achieve key clinical readouts in the first half of 2026.

BioAtla Financial Statement Overview

Summary
BioAtla faces significant financial challenges typical of early-stage biotech firms, with no revenue and consistent operating losses. The low debt is a positive highlight, but negative cash flows and declining equity are concerning for future sustainability.
Income Statement
5
Very Negative
BioAtla has reported zero revenue in the most recent year, reflecting a significant challenge in generating sales. The company has incurred consistent operating losses, which is typical for early-stage biotech firms. There is no gross profit or net profit margin due to lack of revenue, and the EBIT and EBITDA margins are negative, indicating ongoing operational challenges.
Balance Sheet
20
Very Negative
BioAtla's financial leverage appears low, with minimal total debt, resulting in a low debt-to-equity ratio. However, the company has experienced a significant decline in equity over the years, reducing its equity ratio. The return on equity is not meaningful due to negative net income and fluctuating equity levels, raising concerns about shareholder value creation.
Cash Flow
10
Very Negative
The company consistently reports negative operating and free cash flows, reflecting the high cash burn typical of development-stage biotechnology companies. The free cash flow growth rate is negative, indicating increasing cash outflows. The operating cash flow to net income ratio is unavailable due to zero revenue, highlighting the need for external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue11.00M11.00M0.000.00250.00K429.00K
Gross Profit10.77M10.07M-103.73M-1.20M-1.08M409.07K
EBITDA-66.46M-73.94M-122.24M-106.48M-94.07M-33.46M
Net Income-61.88M-69.78M-123.46M-105.28M-95.41M-37.24M
Balance Sheet
Total Assets38.29M52.42M119.66M225.74M254.42M244.94M
Cash, Cash Equivalents and Short-Term Investments32.36M49.05M111.47M215.51M244.98M238.60M
Total Debt554.00K836.00K2.46M3.98M5.37M682.00K
Total Liabilities37.74M38.16M48.99M45.40M43.60M34.96M
Stockholders Equity547.00K14.27M70.67M180.34M210.82M209.97M
Cash Flow
Free Cash Flow-57.40M-71.94M-104.11M-90.69M-63.14M-36.92M
Operating Cash Flow-57.40M-71.94M-104.02M-90.42M-62.21M-36.33M
Investing Cash Flow0.000.00-98.00K-265.00K-924.00K-590.00K
Financing Cash Flow9.13M9.51M77.00K61.21K69.51M271.82M

BioAtla Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.38
Price Trends
50DMA
0.43
Negative
100DMA
0.39
Negative
200DMA
0.89
Negative
Market Momentum
MACD
-0.01
Positive
RSI
42.90
Neutral
STOCH
35.73
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BCAB, the sentiment is Negative. The current price of 0.38 is below the 20-day moving average (MA) of 0.42, below the 50-day MA of 0.43, and below the 200-day MA of 0.89, indicating a bearish trend. The MACD of -0.01 indicates Positive momentum. The RSI at 42.90 is Neutral, neither overbought nor oversold. The STOCH value of 35.73 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BCAB.

BioAtla Risk Analysis

BioAtla disclosed 80 risk factors in its most recent earnings report. BioAtla reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioAtla Peers Comparison

Overall Rating
UnderperformOutperform
Sector (52)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
IPIPA
54
Neutral
$59.95M-121.65%-0.71%-169.29%
52
Neutral
$7.50B0.31-61.87%2.27%17.10%1.59%
43
Neutral
$22.53M-56.49%7.07%
PMPMN
38
Underperform
$14.13M-19.56%98.61%
35
Underperform
$21.97M-246.21%44.38%
33
Underperform
$22.98M-78.32%47.73%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BCAB
BioAtla
0.38
-0.89
-70.08%
LSTA
Lisata Therapeutics
2.62
-0.72
-21.56%
IPA
ImmunoPrecise Antibodies
1.31
0.31
31.00%
ELEV
Elevation Oncology
0.39
-2.40
-86.02%
PMN
ProMIS Neurosciences
0.43
-1.56
-78.39%

BioAtla Corporate Events

Executive/Board Changes
BioAtla Awards Executive Bonuses and Stock Units
Neutral
Mar 14, 2025

On March 11 and 12, 2025, BioAtla, Inc.’s Board of Directors approved cash bonuses for their executive officers based on the company’s achievement of clinical and business milestones in 2024. The bonuses, reflecting 62.5% of the target bonus, were awarded to Richard Waldron, Eric Sievers, and Jay Short, the company’s CFO, CMO, and CEO, respectively. Additionally, the Board granted restricted stock units (RSUs) to these executives under the company’s 2020 Equity Incentive Plan, which will vest over a period starting March 2026, contingent on continued service with the company.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 20, 2025