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Bioatla, Inc. (BCAB)
:BCAB
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BioAtla (BCAB) AI Stock Analysis

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BCAB

BioAtla

(NASDAQ:BCAB)

Rating:35Underperform
Price Target:
BioAtla's stock faces significant challenges, primarily due to its financial position, characterized by a lack of revenue and high cash burn. Despite promising clinical progress and strategic efforts to manage cash, the company's valuation and technical indicators reflect a bearish outlook. The overall score reflects these substantial risks, with some potential upside from clinical developments.
Positive Factors
Clinical Trials
Five patients achieved objective tumor size reductions in various cancer types, including colorectal carcinoma and non-small cell lung cancer.
Drug Efficacy
The drug demonstrated anti-tumor activity in advanced adenocarcinoma patients with a manageable safety profile.
Operational Efficiency
BioAtla reported lower than expected R&D and SG&A expenses, contributing to a better EPS than estimated.
Negative Factors
Financial Performance
BioAtla reported no revenue and a net loss of $0.32 per share, compared to the consensus estimate of a net loss of $0.29 per share.
Pipeline Development
There are uncertainties regarding BioAtla’s pipeline development and a near-term financial overhang.
Stock Valuation
The price target for BioAtla has been lowered to $1 from $5 based on cash/share and platform value.

BioAtla (BCAB) vs. SPDR S&P 500 ETF (SPY)

BioAtla Business Overview & Revenue Model

Company DescriptionBioAtla, Inc., a clinical stage biopharmaceutical company, develops specific and selective antibody-based therapeutics for the treatment of solid tumor cancer. Its lead product candidate is BA3011, a conditionally active biologic (CAB) antibody-drug conjugate (ADC) for soft tissue and bone sarcoma tumors, non-small cell lung cancer (NSCLC), and ovarian cancer. It also develops BA3021, a CAB ADC for multiple solid tumor types, including NSCLC, melanoma, and ovarian cancer; and BA3071, which is a CAB anti-cytotoxic T-lymphocyte-associated antigen 4 antibody for renal cell carcinoma, NSCLC, small cell lung cancer, hepatocellular carcinoma, melanoma, bladder cancer, gastric cancer, and cervical cancer. BioAtla, Inc. was founded in 2007 and is based in San Diego, California.
How the Company Makes MoneyBioAtla makes money primarily through the development and commercialization of its CAB antibody therapeutics. The company's revenue model includes partnerships and collaborations with other pharmaceutical companies for the development and potential commercialization of its drug candidates. These partnerships often involve upfront payments, milestone payments upon achieving certain development or regulatory goals, and potential royalties on future sales of approved therapies. BioAtla may also generate revenue through licensing agreements that allow other companies to use its proprietary technology in their therapeutic development. Additionally, BioAtla may seek funding through public and private investments to support its research and development activities.

BioAtla Earnings Call Summary

Earnings Call Date:Aug 07, 2025
(Q2-2025)
|
% Change Since: -2.63%|
Next Earnings Date:Nov 05, 2025
Earnings Call Sentiment Neutral
The earnings call presented notable scientific and regulatory advancements, particularly with BA3182 and Oz-V, and strategic partnerships aimed at non-dilutive funding. However, financial constraints, including decreased cash reserves and ongoing net losses, underline significant operational challenges.
Q2-2025 Updates
Positive Updates
Progress in BA3182 Phase I Study
BioAtla's dual conditionally binding EpCAM CD3 T cell engager, BA3182, showed evidence of objective tumor reductions in 7 heavily pretreated adenocarcinoma patients across multiple solid tumors. All 5 evaluable patients in the most recent cohort achieved stable disease and continue on treatment.
Strong Performance of CAB-ROR2-ADC Oz-V
Oz-V demonstrated a 45% objective response rate (ORR) and 11.6 months median overall survival in patients with metastatic HPV-positive head and neck cancer, significantly outperforming the standard of care.
Positive FDA Guidance for Oz-V
BioAtla received actionable FDA guidance on a pivotal trial in head and neck cancer, with potential for accelerated approval based on compelling ORR and OS data.
Clinical Progress of Mec-V and Evalstotug
Mec-V showed exceptional overall survival in mKRAS non-small cell lung cancer patients, with 1-year and 2-year survival rates of 67% and 59%. Evalstotug demonstrated potent antitumor activity with reduced immune-mediated adverse events in metastatic melanoma.
Strategic Partnerships and Funding
BioAtla is making progress in partnering discussions, with diligence completed for one asset and reaching the term sheet stage, aiming to close the transaction by year-end.
Negative Updates
Decrease in R&D and G&A Expenses
R&D expenses decreased by $2.5 million and G&A expenses by $0.8 million compared to the previous year, primarily due to a workforce reduction and lower stock-based compensation, indicating cost-cutting measures.
Significant Decrease in Cash and Cash Equivalents
Cash and cash equivalents decreased from $49 million at the end of 2024 to $18.2 million by June 30, 2025, reflecting ongoing cash burn challenges.
Net Loss Reduction
Net loss for the quarter was $18.7 million, a slight improvement from $21.1 million in the previous year, but still indicating financial challenges.
Company Guidance
During the BioAtla Second Quarter 2025 Earnings Call, several key metrics and projections were highlighted, reflecting the company's progress and strategic direction. BioAtla is advancing its clinical trials, particularly focusing on the dual conditionally binding EpCAM CD3 T cell engager, BA3182, showing promise in Phase I trials with stable disease achieved in all five evaluable patients in the latest cohort. The company anticipates a Phase I data readout in the second half of 2025 and further dose expansion in the first half of 2026. Additionally, the CAB-ROR2-ADC Oz-V has demonstrated a 45% objective response rate (ORR) in metastatic HPV-positive head and neck cancer, significantly outperforming the 3.4% ORR of standard therapies. Financially, R&D expenses decreased to $13.7 million from $16.2 million year-over-year, with a net loss of $18.7 million compared to $21.1 million in 2024, and the company reported cash and equivalents of $18.2 million as of June 30, 2025. BioAtla aims to manage expenses and secure non-dilutive funding through partnerships, while also preparing for an FDA meeting to discuss a pivotal Phase III trial for Oz-V.

BioAtla Financial Statement Overview

Summary
BioAtla faces significant financial challenges typical of early-stage biotech firms, with no revenue and consistent operating losses. The low debt is a positive highlight, but negative cash flows and declining equity are concerning for future sustainability.
Income Statement
5
Very Negative
BioAtla has reported zero revenue in the most recent year, reflecting a significant challenge in generating sales. The company has incurred consistent operating losses, which is typical for early-stage biotech firms. There is no gross profit or net profit margin due to lack of revenue, and the EBIT and EBITDA margins are negative, indicating ongoing operational challenges.
Balance Sheet
20
Very Negative
BioAtla's financial leverage appears low, with minimal total debt, resulting in a low debt-to-equity ratio. However, the company has experienced a significant decline in equity over the years, reducing its equity ratio. The return on equity is not meaningful due to negative net income and fluctuating equity levels, raising concerns about shareholder value creation.
Cash Flow
10
Very Negative
The company consistently reports negative operating and free cash flows, reflecting the high cash burn typical of development-stage biotechnology companies. The free cash flow growth rate is negative, indicating increasing cash outflows. The operating cash flow to net income ratio is unavailable due to zero revenue, highlighting the need for external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue11.00M11.00M0.000.00250.00K429.00K
Gross Profit10.25M10.07M-1.22M-1.20M-1.08M-19.50M
EBITDA-63.14M-73.02M-122.24M-105.28M-94.07M-33.46M
Net Income-59.52M-69.78M-123.46M-105.28M-95.41M-35.85M
Balance Sheet
Total Assets27.13M52.42M119.66M225.74M254.42M244.94M
Cash, Cash Equivalents and Short-Term Investments18.21M49.05M111.47M215.51M244.98M238.60M
Total Debt6.04M836.00K2.46M3.98M5.37M682.00K
Total Liabilities43.87M38.16M48.99M45.40M43.60M34.96M
Stockholders Equity-16.75M14.27M70.67M180.34M210.82M209.97M
Cash Flow
Free Cash Flow-52.32M-71.94M-104.11M-90.69M-63.14M-36.92M
Operating Cash Flow-52.32M-71.94M-104.02M-90.42M-62.21M-36.33M
Investing Cash Flow0.000.00-98.00K-265.00K-924.00K-590.00K
Financing Cash Flow8.87M9.51M77.00K61.21M69.51M271.82M

BioAtla Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.37
Price Trends
50DMA
0.39
Positive
100DMA
0.39
Negative
200DMA
0.65
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
54.70
Neutral
STOCH
63.44
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BCAB, the sentiment is Positive. The current price of 0.37 is above the 20-day moving average (MA) of 0.36, below the 50-day MA of 0.39, and below the 200-day MA of 0.65, indicating a neutral trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 54.70 is Neutral, neither overbought nor oversold. The STOCH value of 63.44 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BCAB.

BioAtla Risk Analysis

BioAtla disclosed 80 risk factors in its most recent earnings report. BioAtla reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioAtla Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
61
Neutral
$92.31M-102.69%-3.20%12.24%
51
Neutral
$7.69B-0.19-46.01%2.25%22.94%-0.68%
43
Neutral
$22.15M-63.84%12.95%
38
Underperform
$31.96M-19.56%71.47%
35
Underperform
$21.59M-813.88%49.48%
33
Underperform
$21.62M-78.32%47.73%
$42.70M
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BCAB
BioAtla
0.39
-1.51
-79.47%
LSTA
Lisata Therapeutics
2.51
-0.45
-15.20%
PMN
ProMIS Neurosciences
0.62
-0.67
-51.94%
IPA
ImmunoPrecise Antibodies
2.70
1.74
181.25%
ELEV
Elevation Oncology
0.36
-0.39
-52.00%
JUNS
Jupiter Neurosciences, Inc.
1.24
-4.30
-77.62%

BioAtla Corporate Events

Executive/Board Changes
BioAtla Awards Executive Bonuses and Stock Units
Neutral
Mar 14, 2025

On March 11 and 12, 2025, BioAtla, Inc.’s Board of Directors approved cash bonuses for their executive officers based on the company’s achievement of clinical and business milestones in 2024. The bonuses, reflecting 62.5% of the target bonus, were awarded to Richard Waldron, Eric Sievers, and Jay Short, the company’s CFO, CMO, and CEO, respectively. Additionally, the Board granted restricted stock units (RSUs) to these executives under the company’s 2020 Equity Incentive Plan, which will vest over a period starting March 2026, contingent on continued service with the company.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 20, 2025