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BioAtla (BCAB)
NASDAQ:BCAB
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BioAtla (BCAB) AI Stock Analysis

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BCAB

BioAtla

(NASDAQ:BCAB)

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Underperform 35 (OpenAI - 4o)
Rating:35Underperform
Price Target:
BioAtla's stock faces significant challenges, primarily due to its financial position, characterized by a lack of revenue and high cash burn. Despite promising clinical progress and strategic efforts to manage cash, the company's valuation and technical indicators reflect a bearish outlook. The overall score reflects these substantial risks, with some potential upside from clinical developments.
Positive Factors
Clinical Advancements
The advancement of BioAtla's CAB platform with promising clinical results enhances its competitive edge in biotechnology, potentially leading to successful therapies and partnerships.
Strategic Partnerships
Pursuing strategic partnerships can bolster BioAtla's development capabilities and financial stability, providing access to additional resources and market opportunities.
R&D Expense Reduction
Reducing R&D expenses while maintaining clinical progress indicates effective cost management, potentially extending BioAtla's financial runway and enhancing sustainability.
Negative Factors
Cash Reserves Decline
A significant decrease in cash reserves raises concerns about BioAtla's ability to fund operations and development, potentially necessitating external financing.
Workforce Reduction
Workforce reduction may impact operational capacity and morale, potentially affecting long-term growth and innovation capabilities despite short-term financial relief.
Zero Revenue
The absence of revenue highlights a critical challenge in monetizing BioAtla's innovations, impacting financial sustainability and increasing reliance on external funding.

BioAtla (BCAB) vs. SPDR S&P 500 ETF (SPY)

BioAtla Business Overview & Revenue Model

Company DescriptionBioAtla, Inc. (BCAB) is a biotechnology company focused on the development of Conditionally Active Biologic (CAB) antibody therapeutics. The company operates primarily in the biopharmaceutical sector, leveraging its proprietary CAB technology to create therapies that are activated under specific physiological conditions, enhancing safety and efficacy. BioAtla's core products include a pipeline of CAB antibody candidates aimed at treating various cancers, with a focus on improving patient outcomes through innovative therapeutic solutions.
How the Company Makes MoneyBioAtla makes money primarily through the development and commercialization of its CAB antibody therapeutics. The company's revenue model includes partnerships and collaborations with other pharmaceutical companies for the development and potential commercialization of its drug candidates. These partnerships often involve upfront payments, milestone payments upon achieving certain development or regulatory goals, and potential royalties on future sales of approved therapies. BioAtla may also generate revenue through licensing agreements that allow other companies to use its proprietary technology in their therapeutic development. Additionally, BioAtla may seek funding through public and private investments to support its research and development activities.

BioAtla Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in clinical trials, strategic transactions, and market potential for BioAtla's programs, with robust data supporting their CAB platform's potential. However, financial challenges were noted, including increased net loss and decreased cash reserves.
Q3-2025 Updates
Positive Updates
FDA Alignment on Phase Three Trial Design
BioAtla achieved FDA alignment on the phase three OSV registrational trial design for OPSCC, which includes a dual primary endpoints design for potential accelerated approval followed by full approval.
Development Milestone with Context Therapeutics
Achieved a development milestone under a license agreement with Context Therapeutics related to the dual CAB Nectin 4 TCE program, providing non-dilutive capital and further validating the CAB T cell engager platform.
Compelling Data from CAB Platform Programs
Presented compelling data for dual CAB EpCAM TCE and MACV programs, demonstrating potential for differentiated therapies for difficult-to-treat cancers.
Potential Strategic Transaction
BioAtla is in advanced stages to finalize a strategic transaction with a potential partner by year-end.
Strong Phase Two Data for OSV
Phase two data for OSV in late-line OPSCC patients showed an overall response rate of 45% and a median overall survival of 11.6 months, significantly higher than historical response rates and survival with standard therapies.
Market Opportunity for OSFI
OSFI has demonstrated clinical activity in HPV-positive OPSCC and is projected to achieve worldwide peak sales of $800 million in second-line and later OPS alone, with the total worldwide OPSCC market projected to reach $3 billion by 2032.
Progress in Dual CAB EpCAM T Cell Engager Program
Preliminary data from phase one trial in advanced adenocarcinomas indicate a manageable safety profile and encouraging signs of tumor reductions, with a confirmed partial response at 0.6 mg dose.
MEKV Program's Potential in Soft Tissue Sarcoma
Phase two trial data for MEKV showed a median overall survival of 21.5 months in soft tissue sarcoma patients, compared to 11.5 to 13.6 months for approved agents, with a manageable safety profile.
Negative Updates
Increased Net Loss
Reported a net loss of $15.8 million for the third quarter of 2025, compared to a net loss of $10.6 million in the same quarter of 2024, primarily due to collaboration revenue recorded in 2024 and a non-cash loss on warrant liability in 2025.
Decreased Cash and Cash Equivalents
As of 09/30/2025, BioAtla had $8.3 million in cash and cash equivalents, not including a recent $2 million milestone payment or any R&D funding from collaborations.
Company Guidance
During BioAtla, Inc.'s third quarter 2025 earnings call, the company provided several key metrics and updates. They are in advanced stages of finalizing a strategic transaction with a potential partner by year-end. The FDA has aligned with their phase three OSV registrational trial design for second-line plus oropharyngeal squamous cell carcinoma (OPSCC), targeting dual primary endpoints of overall response rate and overall survival, with potential for accelerated approval. The estimated worldwide peak sales for their OSFI product in second-line OPSCC alone are approximately $800 million, with the total OPSCC market projected to reach $3 billion by 2032. They reported a net loss of $15.8 million for the quarter, an increase from a $10.6 million net loss in the same quarter of 2024. BioAtla, Inc. had $8.3 million in cash and cash equivalents as of September 30, 2025, and expects R&D expenses to decline as they concentrate resources on prioritized programs.

BioAtla Financial Statement Overview

Summary
BioAtla faces significant financial challenges typical of early-stage biotech firms, with no revenue and consistent operating losses. The low debt is a positive highlight, but negative cash flows and declining equity are concerning for future sustainability.
Income Statement
5
Very Negative
BioAtla has reported zero revenue in the most recent year, reflecting a significant challenge in generating sales. The company has incurred consistent operating losses, which is typical for early-stage biotech firms. There is no gross profit or net profit margin due to lack of revenue, and the EBIT and EBITDA margins are negative, indicating ongoing operational challenges.
Balance Sheet
20
Very Negative
BioAtla's financial leverage appears low, with minimal total debt, resulting in a low debt-to-equity ratio. However, the company has experienced a significant decline in equity over the years, reducing its equity ratio. The return on equity is not meaningful due to negative net income and fluctuating equity levels, raising concerns about shareholder value creation.
Cash Flow
10
Very Negative
The company consistently reports negative operating and free cash flows, reflecting the high cash burn typical of development-stage biotechnology companies. The free cash flow growth rate is negative, indicating increasing cash outflows. The operating cash flow to net income ratio is unavailable due to zero revenue, highlighting the need for external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.0011.00M0.000.00250.00K429.00K
Gross Profit-12.46M10.07M-1.22M-1.20M250.00K-19.50M
EBITDA-67.70M-73.02M-122.24M-105.28M-94.07M-33.46M
Net Income-64.71M-69.78M-123.46M-105.28M-95.40M-35.85M
Balance Sheet
Total Assets15.91M52.42M119.66M225.74M254.42M244.94M
Cash, Cash Equivalents and Short-Term Investments8.32M49.05M111.47M215.51M244.98M238.60M
Total Debt6.18M836.00K2.46M3.98M5.37M682.00K
Total Liabilities47.15M38.16M48.99M45.40M43.60M34.96M
Stockholders Equity-31.24M14.27M70.67M180.34M210.82M209.97M
Cash Flow
Free Cash Flow-42.95M-71.94M-104.11M-90.69M-63.14M-36.92M
Operating Cash Flow-57.15M-71.94M-104.02M-90.42M-62.21M-36.33M
Investing Cash Flow0.000.00-98.00K-265.00K-924.00K-590.00K
Financing Cash Flow8.95M9.51M77.00K61.21M69.51M271.82M

BioAtla Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.85
Price Trends
50DMA
0.76
Positive
100DMA
0.60
Positive
200DMA
0.50
Positive
Market Momentum
MACD
0.06
Negative
RSI
51.53
Neutral
STOCH
27.09
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BCAB, the sentiment is Positive. The current price of 0.85 is above the 20-day moving average (MA) of 0.81, above the 50-day MA of 0.76, and above the 200-day MA of 0.50, indicating a bullish trend. The MACD of 0.06 indicates Negative momentum. The RSI at 51.53 is Neutral, neither overbought nor oversold. The STOCH value of 27.09 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for BCAB.

BioAtla Risk Analysis

BioAtla disclosed 80 risk factors in its most recent earnings report. BioAtla reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioAtla Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$42.50M-104.58%1.18%
44
Neutral
$36.29M-1.86-2691.06%44.50%
41
Neutral
$42.11M-1.03-133.09%11.11%20.65%
41
Neutral
-1341.37%-53.61%-93.14%
41
Neutral
$41.24M-14.23%4121.12%83.30%
35
Underperform
$50.01M-0.74-100.00%32.37%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BCAB
BioAtla
0.85
-0.82
-49.10%
ATNM
Actinium Pharmaceuticals
1.45
0.04
2.84%
ADAP
Adaptimmune Therapeutics
0.04
-0.68
-94.44%
LTRN
Lantern Pharma
3.80
0.64
20.25%
IPSC
Century Therapeutics
0.54
-1.14
-67.86%
MAIA
MAIA Biotechnology, Inc.
1.06
-1.10
-50.93%

BioAtla Corporate Events

Executive/Board Changes
BioAtla Awards Executive Bonuses and Stock Units
Neutral
Mar 14, 2025

On March 11 and 12, 2025, BioAtla, Inc.’s Board of Directors approved cash bonuses for their executive officers based on the company’s achievement of clinical and business milestones in 2024. The bonuses, reflecting 62.5% of the target bonus, were awarded to Richard Waldron, Eric Sievers, and Jay Short, the company’s CFO, CMO, and CEO, respectively. Additionally, the Board granted restricted stock units (RSUs) to these executives under the company’s 2020 Equity Incentive Plan, which will vest over a period starting March 2026, contingent on continued service with the company.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 20, 2025