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BioAtla (BCAB)
NASDAQ:BCAB
US Market

BioAtla (BCAB) AI Stock Analysis

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BCAB

BioAtla

(NASDAQ:BCAB)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
$0.33
▼(-2.65% Downside)
The score is primarily constrained by weak financial performance (no TTM revenue, ongoing heavy losses and cash burn, and negative equity). Technicals also reflect sustained bearish momentum (below major moving averages with negative MACD). Offsetting factors include encouraging clinical/regulatory progress and the announced SPV financing, but these are not yet enough to overcome current balance-sheet and funding-risk pressures.
Positive Factors
Proprietary CAB platform
BioAtla's proprietary Conditionally Active Biologic (CAB) platform is a structural competitive advantage, enabling tumor‑selective antibody activation that can improve therapeutic index and tolerability. This platform supports multiple programs and partnership potential, underpinning long‑term pipeline optionality and differentiation.
Regulatory alignment on registrational trial
FDA agreement on a Phase 3 design with dual primary endpoints and an accelerated approval path materially de‑risks development for Oz‑V. Regulatory alignment strengthens the path to a potential approval, supports future commercial planning, and raises the program's strategic value for partners or acquirers over the coming months.
Structured $40M SPV financing for Oz‑V
The SPV deal provides a meaningful near‑term funding tranche and shares development and commercialization costs while leaving BioAtla majority SPV ownership and operational control of the registrational program. This financing reduces immediate dilution pressure and extends runway to advance Phase 3 execution and strategic partnering.
Negative Factors
Deteriorated balance sheet / negative equity
Equity erosion to a negative position is a durable solvency concern that reduces financial flexibility and increases funding risk. Negative net worth limits borrowing capacity, raises counterparty concerns, and makes the company more reliant on equity‑like or structured financings for continued operations and clinical development.
Persistent cash burn and limited runway
Sustained negative operating cash flow and large free cash flow deficits create an ongoing financing imperative. With single‑digit million cash balances and continued R&D spend, the company remains reliant on external financings and milestone payments, elevating dilution and execution risk over the medium term.
Governance and shareholder control actions
Issuing a super‑voting preferred share to secure approval for a reverse split signals governance stress and potential shareholder rights dilution. Such actions can undermine investor confidence, complicate future capital raises, and reflect difficulty securing broad shareholder support for structural remedies to listing or capital challenges.

BioAtla (BCAB) vs. SPDR S&P 500 ETF (SPY)

BioAtla Business Overview & Revenue Model

Company DescriptionBioAtla, Inc., a clinical stage biopharmaceutical company, develops specific and selective antibody-based therapeutics for the treatment of solid tumor cancer. Its lead product candidate is BA3011, a conditionally active biologic (CAB) antibody-drug conjugate (ADC) for soft tissue and bone sarcoma tumors, non-small cell lung cancer (NSCLC), and ovarian cancer. It also develops BA3021, a CAB ADC for multiple solid tumor types, including NSCLC, melanoma, and ovarian cancer; and BA3071, which is a CAB anti-cytotoxic T-lymphocyte-associated antigen 4 antibody for renal cell carcinoma, NSCLC, small cell lung cancer, hepatocellular carcinoma, melanoma, bladder cancer, gastric cancer, and cervical cancer. BioAtla, Inc. was founded in 2007 and is based in San Diego, California.
How the Company Makes MoneyBioAtla makes money primarily through the development and commercialization of its CAB antibody therapeutics. The company's revenue model includes partnerships and collaborations with other pharmaceutical companies for the development and potential commercialization of its drug candidates. These partnerships often involve upfront payments, milestone payments upon achieving certain development or regulatory goals, and potential royalties on future sales of approved therapies. BioAtla may also generate revenue through licensing agreements that allow other companies to use its proprietary technology in their therapeutic development. Additionally, BioAtla may seek funding through public and private investments to support its research and development activities.

BioAtla Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q3-2025)
|
% Change Since: |
Next Earnings Date:Mar 19, 2026
Earnings Call Sentiment Positive
The earnings call highlighted significant progress in clinical trials, strategic transactions, and market potential for BioAtla's programs, with robust data supporting their CAB platform's potential. However, financial challenges were noted, including increased net loss and decreased cash reserves.
Q3-2025 Updates
Positive Updates
FDA Alignment on Phase Three Trial Design
BioAtla achieved FDA alignment on the phase three OSV registrational trial design for OPSCC, which includes a dual primary endpoints design for potential accelerated approval followed by full approval.
Development Milestone with Context Therapeutics
Achieved a development milestone under a license agreement with Context Therapeutics related to the dual CAB Nectin 4 TCE program, providing non-dilutive capital and further validating the CAB T cell engager platform.
Compelling Data from CAB Platform Programs
Presented compelling data for dual CAB EpCAM TCE and MACV programs, demonstrating potential for differentiated therapies for difficult-to-treat cancers.
Potential Strategic Transaction
BioAtla is in advanced stages to finalize a strategic transaction with a potential partner by year-end.
Strong Phase Two Data for OSV
Phase two data for OSV in late-line OPSCC patients showed an overall response rate of 45% and a median overall survival of 11.6 months, significantly higher than historical response rates and survival with standard therapies.
Market Opportunity for OSFI
OSFI has demonstrated clinical activity in HPV-positive OPSCC and is projected to achieve worldwide peak sales of $800 million in second-line and later OPS alone, with the total worldwide OPSCC market projected to reach $3 billion by 2032.
Progress in Dual CAB EpCAM T Cell Engager Program
Preliminary data from phase one trial in advanced adenocarcinomas indicate a manageable safety profile and encouraging signs of tumor reductions, with a confirmed partial response at 0.6 mg dose.
MEKV Program's Potential in Soft Tissue Sarcoma
Phase two trial data for MEKV showed a median overall survival of 21.5 months in soft tissue sarcoma patients, compared to 11.5 to 13.6 months for approved agents, with a manageable safety profile.
Negative Updates
Increased Net Loss
Reported a net loss of $15.8 million for the third quarter of 2025, compared to a net loss of $10.6 million in the same quarter of 2024, primarily due to collaboration revenue recorded in 2024 and a non-cash loss on warrant liability in 2025.
Decreased Cash and Cash Equivalents
As of 09/30/2025, BioAtla had $8.3 million in cash and cash equivalents, not including a recent $2 million milestone payment or any R&D funding from collaborations.
Company Guidance
During BioAtla, Inc.'s third quarter 2025 earnings call, the company provided several key metrics and updates. They are in advanced stages of finalizing a strategic transaction with a potential partner by year-end. The FDA has aligned with their phase three OSV registrational trial design for second-line plus oropharyngeal squamous cell carcinoma (OPSCC), targeting dual primary endpoints of overall response rate and overall survival, with potential for accelerated approval. The estimated worldwide peak sales for their OSFI product in second-line OPSCC alone are approximately $800 million, with the total OPSCC market projected to reach $3 billion by 2032. They reported a net loss of $15.8 million for the quarter, an increase from a $10.6 million net loss in the same quarter of 2024. BioAtla, Inc. had $8.3 million in cash and cash equivalents as of September 30, 2025, and expects R&D expenses to decline as they concentrate resources on prioritized programs.

BioAtla Financial Statement Overview

Summary
BioAtla faces significant financial challenges typical of early-stage biotech firms, with no revenue and consistent operating losses. The low debt is a positive highlight, but negative cash flows and declining equity are concerning for future sustainability.
Income Statement
18
Very Negative
BioAtla has reported zero revenue in the most recent year, reflecting a significant challenge in generating sales. The company has incurred consistent operating losses, which is typical for early-stage biotech firms. There is no gross profit or net profit margin due to lack of revenue, and the EBIT and EBITDA margins are negative, indicating ongoing operational challenges.
Balance Sheet
22
Negative
BioAtla's financial leverage appears low, with minimal total debt, resulting in a low debt-to-equity ratio. However, the company has experienced a significant decline in equity over the years, reducing its equity ratio. The return on equity is not meaningful due to negative net income and fluctuating equity levels, raising concerns about shareholder value creation.
Cash Flow
24
Negative
The company consistently reports negative operating and free cash flows, reflecting the high cash burn typical of development-stage biotechnology companies. The free cash flow growth rate is negative, indicating increasing cash outflows. The operating cash flow to net income ratio is unavailable due to zero revenue, highlighting the need for external financing to sustain operations.
BreakdownTTMDec 2024Dec 2023Dec 2022Dec 2021Dec 2020
Income Statement
Total Revenue0.0011.00M0.000.00250.00K429.00K
Gross Profit-12.46M10.07M-1.22M-1.20M250.00K-19.50M
EBITDA-67.70M-73.02M-122.24M-105.28M-94.07M-33.46M
Net Income-64.71M-69.78M-123.46M-105.28M-95.40M-35.85M
Balance Sheet
Total Assets15.91M52.42M119.66M225.74M254.42M244.94M
Cash, Cash Equivalents and Short-Term Investments8.32M49.05M111.47M215.51M244.98M238.60M
Total Debt6.18M836.00K2.46M3.98M5.37M682.00K
Total Liabilities47.15M38.16M48.99M45.40M43.60M34.96M
Stockholders Equity-31.24M14.27M70.67M180.34M210.82M209.97M
Cash Flow
Free Cash Flow-42.95M-71.94M-104.11M-90.69M-63.14M-36.92M
Operating Cash Flow-57.15M-71.94M-104.02M-90.42M-62.21M-36.33M
Investing Cash Flow0.000.00-98.00K-265.00K-924.00K-590.00K
Financing Cash Flow8.95M9.51M77.00K61.21M69.51M271.82M

BioAtla Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.34
Price Trends
50DMA
0.72
Negative
100DMA
0.69
Negative
200DMA
0.54
Negative
Market Momentum
MACD
-0.13
Positive
RSI
29.25
Positive
STOCH
9.40
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For BCAB, the sentiment is Negative. The current price of 0.34 is below the 20-day moving average (MA) of 0.56, below the 50-day MA of 0.72, and below the 200-day MA of 0.54, indicating a bearish trend. The MACD of -0.13 indicates Positive momentum. The RSI at 29.25 is Positive, neither overbought nor oversold. The STOCH value of 9.40 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for BCAB.

BioAtla Risk Analysis

BioAtla disclosed 80 risk factors in its most recent earnings report. BioAtla reported the most risks in the "Tech & Innovation" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

BioAtla Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
52
Neutral
$39.59M-2.00-104.58%1.18%
52
Neutral
$176.56M-7.40-14.23%4121.12%83.30%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
$20.01M-100.00%32.37%
45
Neutral
$41.49M-1.18-133.09%11.11%20.65%
44
Neutral
$61.10M-2.14-2691.06%44.50%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
BCAB
BioAtla
0.32
-0.17
-35.29%
ATNM
Actinium Pharmaceuticals
1.31
-0.09
-6.43%
LTRN
Lantern Pharma
3.51
-0.18
-4.88%
IPSC
Century Therapeutics
2.30
1.39
153.03%
MAIA
MAIA Biotechnology, Inc.
1.59
-0.41
-20.50%

BioAtla Corporate Events

Delistings and Listing ChangesRegulatory Filings and ComplianceShareholder MeetingsStock Split
BioAtla Creates Super-Voting Share to Advance Reverse Split
Negative
Jan 12, 2026

On January 9, 2026, BioAtla’s board authorized the issuance of a single Series A Junior Preferred “Super-Voting” share to Chairman and CEO Jay M. Short for $0.01, granting him voting power equal to all common shares outstanding, but only on proposals related to a potential reverse stock split, related adjournments, or other board-designated, closely related matters. The special preferred share, which carries no dividend rights, minimal liquidation preference, strict transfer restrictions, and is redeemable by the board for $0.01, was created after stockholders on December 30, 2025 failed to deliver the required two-thirds voting power to approve a reverse stock split, despite majority support, and the special meeting was adjourned and reconvened on January 12, 2026, then again to January 26, 2026, with the new share designed to ensure that if at least two-thirds of the common stock voting at the reconvened meeting supports the reverse stock split, the company can secure formal approval and continue efforts to maintain compliance with Nasdaq listing standards.

The most recent analyst rating on (BCAB) stock is a Hold with a $0.43 price target. To see the full list of analyst forecasts on BioAtla stock, see the BCAB Stock Forecast page.

Business Operations and StrategyPrivate Placements and Financing
BioAtla Announces $40 Million Oncology SPV Investment Deal
Positive
Dec 31, 2025

On December 30–31, 2025, BioAtla, Inc. announced an agreement under which Inversagen AI, LLC, backed by GATC Health Corp and Alliance International Resources Corp., will invest a total of $40 million in a special purpose vehicle (BA 3021 SPV LLC) holding the oncology rights to BioAtla’s Phase 3-stage asset ozuriftamab vedotin (Oz‑V), in exchange for a 35% stake in the SPV, leaving BioAtla with 65% ownership. The deal, structured as a private placement across two closings expected to occur by the end of the first quarter of 2026, will provide BioAtla with an initial $5 million and a further $35 million to fund general operations and a registrational Phase 3 trial of Oz‑V in second-line or later oropharyngeal squamous cell carcinoma (OPSCC), with BioAtla retaining leadership of trial execution through potential accelerated approval and positioning the company to expand Oz‑V into HPV-positive solid tumors while sharing future development and commercialization costs with Inversagen AI.

The most recent analyst rating on (BCAB) stock is a Hold with a $0.78 price target. To see the full list of analyst forecasts on BioAtla stock, see the BCAB Stock Forecast page.

Private Placements and FinancingShareholder MeetingsStock Split
BioAtla Stockholders Approve Share Issuance, Delay Reverse Split
Neutral
Dec 30, 2025

On December 30, 2025, BioAtla, Inc. held a special meeting of stockholders to vote on several capital-related proposals, including approval to issue 20% or more of its outstanding common stock under existing financing agreements and to authorize a potential reverse stock split, as well as the ability to adjourn the meeting if more proxy votes were required. Stockholders approved the issuance of common stock in excess of the exchange cap and the adjournment proposal, but there were not enough votes to approve the reverse stock split, prompting the company to adjourn the meeting and reconvene it virtually on January 12, 2026, to continue soliciting proxies on that item from stockholders of record as of November 25, 2025.

The most recent analyst rating on (BCAB) stock is a Hold with a $0.78 price target. To see the full list of analyst forecasts on BioAtla stock, see the BCAB Stock Forecast page.

Private Placements and Financing
BioAtla Secures $7.5 Million Pre-Paid Advance
Neutral
Nov 21, 2025

On November 20, 2025, BioAtla, Inc. entered into Pre-Paid Advance Agreements with YA II PN, Ltd., Anson Investments Master Fund LP, and Anson East Master Fund LP, securing a $7.5 million advance. The agreement allows for repayment in cash or conversion into common stock shares, with specific pricing conditions. Additionally, BioAtla entered into a Standby Equity Purchase Agreement with Yorkville, enabling the sale of up to $15 million in common stock over 36 months. These financial arrangements are designed to provide BioAtla with capital flexibility, subject to customary conditions and limitations, potentially impacting its market operations and stakeholder interests.

The most recent analyst rating on (BCAB) stock is a Buy with a $10.00 price target. To see the full list of analyst forecasts on BioAtla stock, see the BCAB Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 15, 2026