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Aytu BioScience Inc (AYTU)
NASDAQ:AYTU
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Aytu BioScience (AYTU) AI Stock Analysis

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AYTU

Aytu BioScience

(NASDAQ:AYTU)

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Neutral 48 (OpenAI - 4o)
Rating:48Neutral
Price Target:
$2.00
▼(-8.68% Downside)
Aytu BioScience's overall stock score reflects significant financial challenges and bearish technical indicators. While the company shows strategic focus on new product launches and maintains a strong cash position, ongoing losses and valuation concerns weigh heavily on the score.
Positive Factors
EXXUA Launch Progress
The timely launch of EXXUA, with strategic advancements, indicates potential for significant market impact, enhancing long-term growth prospects in the major depressive disorder treatment market.
Patent Extension for EXXUA
The patent extension for EXXUA strengthens Aytu's competitive position by securing exclusive rights, potentially leading to sustained revenue from this product line.
Strong Cash Position
A strong cash position provides financial flexibility to invest in growth opportunities and manage operational challenges, supporting long-term stability.
Negative Factors
Decline in Pediatric Portfolio Revenue
The decline in pediatric portfolio revenue highlights operational challenges and potential market share loss, impacting long-term revenue diversification.
Gross Margin Decline
A declining gross margin indicates rising costs or pricing pressures, which could erode profitability and affect long-term financial health.
Regulatory Concerns on Fluoride Products
Regulatory scrutiny on fluoride products could lead to increased compliance costs or restrictions, affecting future product lines and revenue streams.

Aytu BioScience (AYTU) vs. SPDR S&P 500 ETF (SPY)

Aytu BioScience Business Overview & Revenue Model

Company DescriptionAytu BioScience, Inc. is a specialty pharmaceutical company focused on developing and commercializing innovative products in the field of urology, pediatrics, and other therapeutic areas. The company primarily aims to address unmet medical needs through its proprietary products and partnerships, offering solutions that improve patient care and outcomes. Aytu's core products include various prescription medications and diagnostic tools designed to enhance the treatment of conditions such as testosterone deficiency and other urological disorders.
How the Company Makes MoneyAytu BioScience generates revenue through the sale of its pharmaceutical products and diagnostic tests. The company has a diversified revenue model that includes direct sales of its proprietary products, as well as partnerships with other pharmaceutical companies for co-promotion and distribution. Key revenue streams are derived from product sales in the urology and pediatric markets, where Aytu has established a presence. Additionally, the company may benefit from licensing agreements, collaborations, and research grants that contribute to its financial performance. Strategic partnerships with healthcare providers and institutions also play a crucial role in expanding its market reach and enhancing sales.

Aytu BioScience Key Performance Indicators (KPIs)

Any
Any
Revenue by Product
Revenue by Product
Chart Insights
Data provided by:The Fly

Aytu BioScience Earnings Call Summary

Earnings Call Date:Nov 13, 2025
(Q1-2026)
|
% Change Since: |
Next Earnings Date:Feb 18, 2026
Earnings Call Sentiment Neutral
The earnings call reflects a company focused on significant upcoming product launches and managing existing portfolio challenges. While the performance of the ADHD portfolio and progress towards the EXXUA launch highlight growth and strategic focus, declines in certain segments and regulatory concerns pose challenges.
Q1-2026 Updates
Positive Updates
Positive Revenue Performance in ADHD Portfolio
Net revenue for the ADHD portfolio increased by approximately 10% year-over-year when excluding a one-time rebate benefit from the previous year, showcasing strong performance against expectations.
EXXUA Launch Progress
The EXXUA launch remains on track for the end of calendar 2025 with significant advancements in KOL engagement, sales force training, and product positioning.
Patent Extension for EXXUA
Successfully extended the EXXUA method of use patent to September 2030, enhancing intellectual property protection.
Strong Cash Position
Cash and cash equivalents were $32.6 million at the end of the quarter, up from $31 million in the previous quarter.
Negative Updates
Decline in Pediatric Portfolio Revenue
Pediatric portfolio revenue decreased to $0.7 million from $1.3 million in the previous year due to manufacturing delays and deemphasis on marketing.
Gross Margin Decline
Gross margin decreased to 66% from 72% in the previous year, although this was adjusted to 65% when excluding a one-time rebate.
Regulatory Concerns on Fluoride Products
FDA issued a communication regarding fluoride-containing drugs, although the impact is expected to be limited with only $300,000 in revenue from fluoride products this quarter.
Company Guidance
During the Aytu BioPharma Fiscal 2026 Q1 earnings call, the company reported net revenue of $13.9 million, with their ADHD portfolio showing a 10% increase in net revenue compared to the previous year, when excluding a one-time rebate benefit. The EXXUA launch is on track for the end of calendar year 2025, with significant advancements in product manufacturing, sales force training, and marketing strategies. The company is maintaining a sales force of approximately 40 people and aligning territories to optimize patient access. Aytu anticipates a $50 million operational expenditure for fiscal 2026, inclusive of a $10 million EXXUA launch investment. Cash and cash equivalents stood at $32.6 million as of September 30, 2025. The company projects that achieving quarterly net revenue of $17.3 million will bring them to breakeven, emphasizing their confidence in the potential of EXXUA as a transformative product for treating major depressive disorder.

Aytu BioScience Financial Statement Overview

Summary
Aytu BioScience faces significant financial challenges, with declining revenues and persistent losses impacting profitability. The company maintains a manageable debt level, but its negative return on equity and cash flow issues highlight the need for strategic improvements to enhance financial stability and growth prospects.
Income Statement
45
Neutral
Aytu BioScience's income statement reveals challenges with profitability and revenue growth. The company has experienced a decline in revenue over the past year, with a negative revenue growth rate of -4.10%. Gross profit margin remains relatively strong at 69.04%, indicating efficient production, but the net profit margin is negative at -20.43%, reflecting ongoing losses. EBIT and EBITDA margins are also negative, highlighting operational inefficiencies.
Balance Sheet
50
Neutral
The balance sheet shows a moderate debt-to-equity ratio of 0.10, suggesting manageable leverage. However, the return on equity is significantly negative at -71.51%, indicating poor returns for shareholders. The equity ratio stands at 15.27%, showing a reasonable proportion of equity financing relative to total assets.
Cash Flow
40
Negative
Cash flow analysis indicates a concerning decline in free cash flow growth at -62.28%. The operating cash flow to net income ratio is negative, reflecting cash flow challenges. However, the free cash flow to net income ratio is positive at 1.12, suggesting that free cash flow covers net losses, albeit with limited margin.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue63.70M66.38M65.18M107.40M96.67M65.63M
Gross Profit43.03M45.83M49.05M66.63M50.28M29.20M
EBITDA-5.47M-4.67M1.41M-3.27M-27.96M-29.04M
Net Income-13.07M-13.56M-15.84M-17.05M-108.78M-58.29M
Balance Sheet
Total Assets124.99M124.18M118.86M137.84M137.62M265.67M
Cash, Cash Equivalents and Short-Term Investments32.63M30.95M20.01M22.98M19.36M49.65M
Total Debt1.86M22.94M16.42M30.43M18.19M30.97M
Total Liabilities101.82M105.21M91.14M98.48M93.31M128.10M
Stockholders Equity23.17M18.97M27.72M39.36M44.31M137.57M
Cash Flow
Free Cash Flow-1.46M-5.17M-1.72M-5.13M-28.82M-25.96M
Operating Cash Flow-1.36M-1.94M-1.39M-5.13M-28.82M-25.96M
Investing Cash Flow-2.94M-2.56M-329.00K-117.00K-3.25M-2.78M
Financing Cash Flow16.83M15.44M-1.26M8.87M1.53M30.31M

Aytu BioScience Technical Analysis

Technical Analysis Sentiment
Positive
Last Price2.19
Price Trends
50DMA
2.16
Positive
100DMA
2.25
Negative
200DMA
1.88
Positive
Market Momentum
MACD
-0.03
Negative
RSI
55.23
Neutral
STOCH
66.80
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AYTU, the sentiment is Positive. The current price of 2.19 is above the 20-day moving average (MA) of 2.09, above the 50-day MA of 2.16, and above the 200-day MA of 1.88, indicating a bullish trend. The MACD of -0.03 indicates Negative momentum. The RSI at 55.23 is Neutral, neither overbought nor oversold. The STOCH value of 66.80 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AYTU.

Aytu BioScience Risk Analysis

Aytu BioScience disclosed 59 risk factors in its most recent earnings report. Aytu BioScience reported the most risks in the "Finance & Corporate" category.
Finance & Corporate - Financial and accounting risks. Risks related to the execution of corporate activity and strategy
Latest Risks Added 0 New Risks

Aytu BioScience Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
$21.11M-0.76-50.23%-15.61%-68.96%
47
Neutral
$13.54M-29.320.27%75.19%
41
Neutral
$20.93M-0.68-63.82%
40
Neutral
$6.77M-0.23-37.38%-22.60%53.82%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AYTU
Aytu BioScience
2.19
0.56
34.36%
TXMD
TherapeuticsMD
1.70
0.33
24.09%
COSM
Cosmos Holdings
0.64
-0.16
-20.00%
FLGC
Flora Growth
8.26
-58.43
-87.61%
GELS
Gelteq Limited
1.08
-2.74
-71.73%

Aytu BioScience Corporate Events

Aytu BioPharma Reports Q1 2026 Earnings and EXXUA Launch Plans
Nov 14, 2025

Aytu BioPharma, Inc. is a pharmaceutical company that focuses on developing innovative medicines for complex central nervous system diseases, including treatments for major depressive disorder (MDD) and attention deficit-hyperactivity disorder (ADHD). The company is committed to improving patient outcomes through its specialized patient access programs.

Aytu BioPharma’s Optimistic Earnings Call Highlights ExuA Launch
Sep 25, 2025

Aytu BioPharma’s recent earnings call was marked by a sense of optimism and strategic focus. The company expressed significant enthusiasm about the upcoming launch of ExuA, a novel treatment for major depressive disorder, and celebrated its third consecutive year of positive adjusted EBITDA. However, the call also acknowledged challenges such as a decline in gross margin and potential competition in the ADHD portfolio, which could pose hurdles moving forward.

Aytu BioPharma Reports Fiscal 2025 Earnings and EXXUA Launch Plans
Sep 24, 2025

Aytu BioPharma, Inc. is a pharmaceutical company dedicated to developing innovative treatments for complex central nervous system diseases, with a focus on improving patient quality of life. The company offers prescription products for conditions such as major depressive disorder and ADHD.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 15, 2025