Commercial Launch of ExuA — First-in-Class 5-HT1A Agonist
Launched ExuA (first and only FDA-approved 5-HT1A agonist for MDD); commercial launch underway with early commercial activity and multi-channel promotional plan.
Early Prescription and Prescriber Adoption
Over 100 doctors have prescribed ExuA and scripts have been written from 27 states in the first ~30 days; first refills already appearing and early patient feedback reported as positive and well tolerated.
RxConnect Driven Access and Coverage
Aytu RxConnect platform supporting patient access (caps out-of-pocket at $50 for commercially insured), guiding payer contracting that currently covers ~60% of commercially insured MDD patients; RxConnect dispenses ~85% of branded ADHD prescriptions, demonstrating distribution/patient channel strength.
ADHD Portfolio Resiliency
ADHD net revenue of $13.2M for the quarter, only a slight decrease from prior year ($13.8M, down ~4.3%) and essentially flat sequentially versus Q1, despite Salesforce reprioritization and recent ANDA entry by Teva.
Pediatric Revenue Sequential Improvement
Pediatric portfolio net revenue increased sequentially from $0.715M in Q1 to $1.7M in Q2 (approximately +138% sequential), indicating stabilization after prior-quarter returns reduction.
Launch Spend Efficiency
Initial ExuA launch budget reduced from $10M to under $8M due to execution efficiencies; one-time launch costs estimated ~ $3M of the ~$8M.
Supply Readiness and Scalability
Management reports adequate supply and API/components on hand at contract manufacturer to scale substantially beyond initial production runs if demand exceeds expectations.