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Immutep Ltd (AU:IMM)
:IMM

Immutep Ltd (IMM) AI Stock Analysis

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AU:IMM

Immutep Ltd

(OTC:IMM)

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Neutral 52 (OpenAI - 4o)
Rating:52Neutral
Price Target:
AU$0.32
▲(24.23% Upside)
Immutep Ltd's overall stock score is primarily impacted by its financial performance challenges, including persistent losses and negative cash flows. The technical analysis provides some positive signals with the stock trading above key moving averages, indicating bullish momentum. However, the valuation remains weak due to a negative P/E ratio, reflecting the company's lack of profitability. The absence of earnings call and corporate events data means these factors do not influence the score.
Positive Factors
Strategic Collaboration
The collaboration with Dr. Reddy's provides Immutep with significant milestone payments and potential royalties, enhancing long-term revenue potential and market reach outside key pharmaceutical regions.
Product Development
Positive trial data presentation indicates progress in product development, potentially leading to successful treatments and future revenue streams, strengthening Immutep's market position in oncology.
R&D Incentives
Securing R&D incentives supports Immutep's financial position, enabling continued investment in innovation and clinical trials, which is crucial for long-term growth in the biotech sector.
Negative Factors
Persistent Losses
Ongoing financial losses indicate operational inefficiencies and challenges in achieving profitability, which could hinder long-term sustainability and growth in the competitive biotech industry.
Negative Cash Flows
Negative cash flows reflect cash management challenges, limiting Immutep's ability to invest in growth opportunities and potentially impacting its financial stability and operational flexibility.
Negative Margins
Negative profit margins suggest Immutep is struggling to cover costs, which could affect its ability to sustain operations and compete effectively in the biotech sector over the long term.

Immutep Ltd (IMM) vs. iShares MSCI Australia ETF (EWA)

Immutep Ltd Business Overview & Revenue Model

Company DescriptionImmutep Ltd (IMM) is a biotechnology company focused on developing innovative immunotherapy treatments for cancer and autoimmune diseases. The company specializes in the discovery and development of LAG-3 (Lymphocyte Activation Gene-3) related products, which are designed to enhance the immune response against tumors and regulate immune activity in autoimmune disorders. Immutep operates primarily within the biopharmaceutical sector, leveraging its proprietary technologies to create therapies that aim to improve patient outcomes in oncology and beyond.
How the Company Makes MoneyImmutep generates revenue primarily through a combination of collaborations, partnerships, and potential product sales. The company engages in strategic collaborations with larger pharmaceutical companies that often include upfront payments, milestone payments based on development progress, and royalties on future sales of products developed through these partnerships. Additionally, Immutep may receive funding through government grants and research initiatives aimed at advancing their clinical programs. Their focus on clinical trials and research grants allows them to explore new therapeutic avenues and expand their product pipeline, which can lead to future monetization through licensing agreements or direct sales once therapies are approved.

Immutep Ltd Financial Statement Overview

Summary
Immutep Ltd faces significant financial challenges with persistent losses and negative cash flows. Despite a strong equity position and low leverage, the company's inability to generate profits and positive cash flows is concerning. Improvements in operational efficiency and revenue generation are needed for financial stability.
Income Statement
35
Negative
Immutep Ltd has shown modest revenue growth, but the company is struggling with negative margins across the board. The gross profit margin and net profit margin are both negative, indicating that the company is not currently profitable. The EBIT and EBITDA margins are also negative, suggesting operational inefficiencies. Overall, the income statement reflects significant challenges in achieving profitability.
Balance Sheet
50
Neutral
The balance sheet shows a low debt-to-equity ratio, indicating conservative leverage and a strong equity position. However, the return on equity is negative, reflecting ongoing losses. The equity ratio is relatively healthy, suggesting a stable capital structure, but the company's inability to generate positive returns remains a concern.
Cash Flow
40
Negative
The cash flow statement highlights significant negative operating and free cash flows, although there is a notable improvement in free cash flow growth. The operating cash flow to net income ratio is negative, indicating cash flow challenges. The free cash flow to net income ratio is slightly above 1, suggesting that cash flow is somewhat aligned with net income, but overall cash flow performance is weak.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue5.04M5.04M3.84M3.51M170.37K3.86M
Gross Profit-56.37M-56.37M-37.70M1.44M-1.89M1.79M
EBITDA-62.88M-62.88M-44.54M-42.88M-31.87M-20.72M
Net Income-61.43M-61.43M-42.72M-39.90M-32.21M-29.90M
Balance Sheet
Total Assets156.98M156.98M201.58M147.45M102.17M82.03M
Cash, Cash Equivalents and Short-Term Investments129.69M129.69M181.88M123.42M80.00M60.13M
Total Debt1.63M1.63M1.59M1.23M1.73M2.82M
Total Liabilities13.35M13.35M12.06M10.98M8.09M8.76M
Stockholders Equity143.64M143.64M189.52M136.47M94.08M73.27M
Cash Flow
Free Cash Flow-62.10M-62.10M-35.75M-35.93M-30.25M-17.66M
Operating Cash Flow-62.05M-62.05M-34.82M-35.88M-30.23M-17.64M
Investing Cash Flow-38.53M-38.53M-21.02M-31.00K-22.91K-15.60K
Financing Cash Flow-525.12K-525.12K95.18M76.04M50.33M52.68M

Immutep Ltd Technical Analysis

Technical Analysis Sentiment
Positive
Last Price0.26
Price Trends
50DMA
0.28
Positive
100DMA
0.27
Positive
200DMA
0.27
Positive
Market Momentum
MACD
<0.01
Negative
RSI
63.78
Neutral
STOCH
35.14
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:IMM, the sentiment is Positive. The current price of 0.26 is below the 20-day moving average (MA) of 0.27, below the 50-day MA of 0.28, and below the 200-day MA of 0.27, indicating a bullish trend. The MACD of <0.01 indicates Negative momentum. The RSI at 63.78 is Neutral, neither overbought nor oversold. The STOCH value of 35.14 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Positive sentiment for AU:IMM.

Immutep Ltd Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
54
Neutral
AU$518.99M-27.89%67.26%
52
Neutral
AU$375.80M-35.86%-19.21%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
47
Neutral
AU$294.19M-20.59-83.97%1271.12%36.87%
41
Neutral
AU$97.88M-42.68%63.46%
41
Neutral
$100.90M-83.09%55.94%
40
Underperform
AU$106.68M-13.09-47.98%700.00%26.88%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:IMM
Immutep Ltd
0.32
-0.03
-9.86%
AU:IMU
Imugene
0.35
-1.05
-75.25%
AU:ATH
Alterity Therapeutics
0.01
0.00
0.00%
AU:DXB
Dimerix Limited
0.58
0.20
52.63%
AU:RAC
Race Oncology Ltd.
2.78
1.39
100.00%
AU:ALA
Arovella Therapeutics Limited
0.08
-0.10
-56.00%

Immutep Ltd Corporate Events

Immutep Ltd Announces Director’s Interest Change
Dec 5, 2025

Immutep Ltd announced a change in the director’s interest, specifically involving Dr. Russell John Howard. The changes include the acquisition and conversion of performance rights into ordinary shares, as approved by shareholders at recent annual general meetings. This adjustment reflects Dr. Howard’s decision to take a portion of his fees in performance rights, aligning his interests with the company’s long-term growth and shareholder value.

Immutep Ltd Director Acquires Performance Rights as Remuneration
Dec 5, 2025

Immutep Ltd announced a change in the director’s interest, with Mr. Pete Meyers acquiring 2,058,631 Performance Rights as remuneration for his services. This acquisition, approved at the Annual General Meeting, reflects the company’s strategy to align director compensation with shareholder interests, potentially impacting its governance and stakeholder relations.

Immutep Director’s Interest Update Reflects Strategic Alignment
Dec 5, 2025

Immutep Limited announced a change in the interest of its director, Lis Boyce, who acquired 707,232 Performance Rights and 166,667 Fully Paid Ordinary Shares. These changes were part of a remuneration package approved at the Annual General Meeting, reflecting the company’s strategy to align director compensation with performance and shareholder interests.

Immutep Limited Announces New Securities Quotation on ASX
Dec 5, 2025

Immutep Limited has announced the issuance of 1,800,968 ordinary fully paid securities, which are set to be quoted on the Australian Securities Exchange (ASX) as of December 5, 2025. This move is part of the company’s strategy to enhance its financial position and support its ongoing research and development efforts in the biotechnology sector, potentially impacting its market presence and offering new opportunities for stakeholders.

Immutep Limited Issues New Performance Rights to Employees
Dec 2, 2025

Immutep Limited announced the issuance of 4,339,509 performance rights as part of an employee incentive scheme, which are not intended to be quoted on the ASX. This move is likely to enhance employee engagement and align their interests with the company’s growth objectives, potentially strengthening Immutep’s position in the competitive biotechnology market.

Immutep’s Eftilagimod Alfa Shows Promising Results in Breast Cancer Trial
Dec 2, 2025

Immutep Limited announced new data from its AIPAC-003 Phase II trial, which will be presented at the 2025 San Antonio Breast Cancer Symposium. The trial evaluated the combination of eftilagimod alfa (efti) and paclitaxel in heavily pretreated metastatic breast cancer patients, achieving strong objective response rates and immune activation. The study successfully met the FDA’s Project Optimus requirements, establishing 30 mg as the optimal biological dose for efti, which is crucial for ongoing and future clinical programs. This development is strategically important for Immutep’s oncology pipeline, including its global Phase III trial with MSD’s KEYTRUDA® for non-small cell lung cancer.

Immutep Ltd Updates Business Strategy at AGM 2025
Nov 27, 2025

Immutep Ltd’s recent presentation at their Annual General Meeting 2025 provided an update on the company’s business activities. The presentation emphasized the company’s ongoing efforts and strategic plans, although it included forward-looking statements subject to various risks and uncertainties. Stakeholders are advised to consider these factors carefully, as actual results may differ from current expectations.

Immutep’s EFTISARC-NEO Trial Shows Promising Results in Soft Tissue Sarcoma
Nov 12, 2025

Immutep Limited announced promising results from its EFTISARC-NEO Phase II trial, which were presented at the CTOS 2025 Annual Meeting. The trial demonstrated significant tumor hyalinization/fibrosis in patients with soft tissue sarcoma (STS) using a novel combination of eftilagimod alfa (efti) with radiotherapy and KEYTRUDA. This combination showed a strong immune response, potentially leading to better patient outcomes and survival rates. The findings suggest that efti could be beneficial in treating early-stage cancers, expanding its role in the cancer treatment landscape.

Immutep Secures A$4.6 Million R&D Tax Incentive from French Government
Nov 3, 2025

Immutep Limited has received a €2,588,954 (~ A$4,567,769) R&D tax incentive payment from the French Government under the Crédit d’Impôt Recherche scheme. This funding will support the global clinical development of eftilagimod alfa and IMP761, enhancing Immutep’s operations and potentially strengthening its position in the biotechnology industry.

Immutep Limited Announces 2025 AGM with Key Resolutions
Oct 23, 2025

Immutep Limited has announced its 2025 Annual General Meeting (AGM) scheduled for November 27, 2025, in Sydney, with provisions for a live webcast for those unable to attend in person. The AGM will address the company’s financial statements and include a resolution on the adoption of the Remuneration Report, which is advisory and non-binding, reflecting the company’s commitment to transparency and shareholder engagement.

Immutep Limited Releases 2025 Corporate Governance Statement
Oct 23, 2025

Immutep Limited has released its corporate governance statement for the financial year ending 30 June 2025, which is available on their website. The statement, approved by the board, outlines the company’s adherence to the ASX Corporate Governance Council’s principles and recommendations, highlighting its commitment to transparency and accountability in its operations. This disclosure is crucial for stakeholders as it ensures compliance with governance standards, potentially impacting the company’s reputation and investor confidence.

Immutep Ltd Releases 2025 Annual Report Highlighting Strategic Developments
Oct 23, 2025

Immutep Ltd has released its annual report for the year ending June 30, 2025, detailing its financial performance and strategic developments. The report highlights the company’s ongoing commitment to advancing its immunotherapy pipeline, which could significantly impact its market position and offer potential benefits to stakeholders in the biotechnology sector.

Immutep’s Efti Shows Promising Results in Lung Cancer Treatment
Oct 19, 2025

Immutep Limited has announced promising results from its INSIGHT-003 trial, presented at the ESMO Congress 2025, showcasing a novel combination of eftilagimod alfa (efti) with KEYTRUDA and chemotherapy. This combination has demonstrated strong objective response rates and disease control rates in first-line non-small cell lung cancer (1L NSCLC) patients across all PD-L1 expression levels, particularly benefiting those with low and no PD-L1 expression. The trial results suggest that efti could significantly alter the treatment landscape for 1L NSCLC, providing a new standard of care and addressing the high unmet need in patients with PD-L1 expression under 50%.

Immutep’s Efti Shows Promising Results in Soft Tissue Sarcoma Trial
Oct 19, 2025

Immutep Limited announced positive results from its EFTISARC-NEO Phase II trial, which evaluated the novel combination of eftilagimod alfa (efti) with radiotherapy and KEYTRUDA® in treating resectable soft tissue sarcoma (STS). The trial met its primary endpoint, achieving a 51.5% tumor hyalinization/fibrosis rate, significantly surpassing the historical 15% rate from standard radiotherapy alone. This outcome suggests potential improvements in overall and recurrence-free survival for STS patients, addressing a critical unmet medical need. The findings, presented at the ESMO Congress 2025, highlight the promising efficacy and safety profile of efti, potentially paving the way for new therapeutic options in STS treatment.

Immutep Completes FDA Project Optimus, Advances Cancer Immunotherapy
Oct 12, 2025

Immutep Limited has successfully completed the FDA’s Project Optimus requirements, confirming 30 mg as the optimal biological dose for its immunotherapy candidate efti, which is significant for its oncology pipeline and future Biological License Applications. This development is strategically important for Immutep’s ongoing and future clinical trials, including the Phase III TACTI-004 trial for non-small cell lung cancer, positioning the company to advance its novel immunotherapy to market and address global cancer patient needs.

Immutep Achieves Key Milestone in Phase III Lung Cancer Trial
Oct 8, 2025

Immutep Limited has announced a significant milestone in its TACTI-004 (KEYNOTE-F91) Phase III trial for treating advanced non-small cell lung cancer (NSCLC). The trial, which combines eftilagimod alfa with KEYTRUDA and chemotherapy, has enrolled over 170 patients, surpassing the number needed for futility analysis. With over 100 clinical sites activated across 24 countries, the trial is on track for a futility analysis in early 2026. This development could potentially transform the treatment landscape for NSCLC, a major cancer type with high unmet medical needs, by enhancing response rates and improving efficacy regardless of PD-L1 expression.

Immutep Director Converts Performance Rights into Shares
Oct 8, 2025

Immutep Ltd announced a change in the director’s interest, where Mr. Pete Meyers converted 388,889 performance rights into fully paid ordinary shares. This change reflects the director’s compensation strategy, where he receives part of his fees in performance rights, aligning his interests with those of the shareholders.

Immutep Ltd Announces Director’s Interest Change
Oct 8, 2025

Immutep Ltd has announced a change in the interest of its director, Dr. Frederic Triebel, involving the conversion of 900,000 performance rights into fully paid ordinary shares. This adjustment, which was previously approved by shareholders, reflects the company’s ongoing commitment to aligning executive incentives with shareholder interests, potentially impacting its market perception and stakeholder confidence.

Immutep Ltd Announces Director’s Acquisition of Shares
Oct 8, 2025

Immutep Ltd announced a change in the director’s interest, with Mr. Marc Voigt acquiring 1,200,000 fully paid ordinary shares through the vesting and exercise of performance rights. This change reflects the company’s ongoing commitment to aligning executive interests with shareholder value, potentially impacting investor confidence and market perception positively.

Immutep Ltd Issues New Shares on ASX
Oct 1, 2025

Immutep Ltd has announced the issuance of 4,055,555 fully paid ordinary shares, which will be quoted on the Australian Securities Exchange (ASX) starting October 1, 2025. This move is part of the company’s strategy to enhance its capital structure and potentially strengthen its market position, offering stakeholders an opportunity to invest in its growth and development.

Immutep Collaborates with GW Cancer Center on Efti Trial for Breast Cancer
Sep 21, 2025

Immutep Limited has announced a research collaboration with the George Washington University Cancer Center to initiate a Phase II trial evaluating eftilagimod alfa (efti) as a neoadjuvant therapy for early-stage HR+/HER2-negative breast cancer. The trial will explore efti’s potential to activate a broad anti-cancer immune response, potentially leading to high pathologic complete response rates and improved disease-free survival. This collaboration allows Immutep to expand its clinical pipeline cost-effectively and further positions efti as a promising immunotherapy in both metastatic and neoadjuvant cancer settings.

Immutep’s Phase II Trial Data on Soft Tissue Sarcoma to be Presented at CTOS 2025
Sep 8, 2025

Immutep Limited announced that data from its EFTISARC-NEO Phase II trial will be presented at the Connective Tissue Oncology Society (CTOS) 2025 Annual Meeting. This trial is the first to evaluate eftilagimod alpha in a neoadjuvant setting combined with radiotherapy and pembrolizumab for soft tissue sarcoma, an orphan disease with significant unmet medical needs. The trial, conducted in Poland and funded by the Polish government, could have implications for the treatment of soft tissue sarcoma, potentially improving outcomes in a field with poor prognosis.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 10, 2025