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Imugene (AU:IMU)
ASX:IMU

Imugene (IMU) AI Stock Analysis

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AU:IMU

Imugene

(Sydney:IMU)

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Neutral 41 (OpenAI - 4o)
Rating:41Neutral
Price Target:
AU$0.50
▲(51.52% Upside)
Imugene's overall stock score is primarily impacted by its significant financial challenges, including substantial revenue declines and ongoing losses. The technical analysis indicates a bearish trend, while valuation metrics are concerning due to negative profitability. The absence of earnings call data and corporate events means these factors do not influence the score.
Positive Factors
Low Leverage
A low debt-to-equity ratio indicates a conservative capital structure, providing financial flexibility and reducing risk from debt servicing.
Strategic Collaborations
Collaborations can enhance R&D capabilities, provide funding, and facilitate market entry, supporting long-term growth and innovation.
High Gross Profit Margin
A high gross profit margin suggests efficient production and pricing strategies, which can support profitability if operational inefficiencies are addressed.
Negative Factors
Negative Revenue Growth
Substantial revenue declines indicate challenges in market demand or competitive positioning, impacting long-term financial stability.
Ongoing Losses
Persistent losses reflect operational inefficiencies and high costs, which can hinder investment in growth and innovation.
Negative Cash Flow
Negative cash flow from operations suggests difficulties in sustaining business activities without external funding, impacting financial resilience.

Imugene (IMU) vs. iShares MSCI Australia ETF (EWA)

Imugene Business Overview & Revenue Model

Company DescriptionImugene Limited (ASX: IMU) is a biotechnology company focused on the development of immunotherapies for the treatment of cancer. The company operates in the biopharmaceutical sector, primarily targeting the development of innovative cancer treatments that harness the body’s immune system to fight tumors. Imugene’s core products include oncolytic virotherapy and other immunotherapy candidates designed to enhance the immune response against cancer cells.
How the Company Makes MoneyImugene generates revenue primarily through a combination of research grants, partnerships, and collaborations with larger pharmaceutical companies. The company may receive milestone payments and royalties from these partnerships, particularly as its drug candidates progress through various stages of clinical trials. Additionally, Imugene may also generate income from licensing agreements for its proprietary technologies and intellectual property. The company’s strategic collaborations with research institutions and pharmaceutical companies contribute to its funding and revenue, enabling it to advance its product pipeline and bring therapies to market.

Imugene Financial Statement Overview

Summary
Imugene faces significant financial challenges, particularly in terms of profitability and cash flow generation. The company has experienced substantial revenue declines and continues to operate at a loss, as evidenced by negative profit margins and return on equity. While the balance sheet shows low leverage, the negative cash flow metrics highlight the need for improved operational efficiency and revenue growth to achieve financial stability.
Income Statement
35
Negative
Imugene's income statement shows significant challenges with profitability and revenue growth. The company has experienced a negative revenue growth rate of -338.95% in the most recent year, indicating a substantial decline in revenue. The net profit margin is also deeply negative at -15.70%, reflecting ongoing losses. Despite a high gross profit margin of 100%, the negative EBIT and EBITDA margins highlight operational inefficiencies and high costs relative to revenue.
Balance Sheet
45
Neutral
The balance sheet reveals a relatively low debt-to-equity ratio of 0.24, suggesting limited leverage and a conservative capital structure. However, the return on equity is negative at -153.27%, indicating that the company is not generating profits from its equity base. The equity ratio stands at 53.89%, showing a moderate level of equity financing relative to total assets.
Cash Flow
40
Negative
Imugene's cash flow statement indicates challenges with cash generation. The operating cash flow to net income ratio is negative, reflecting cash outflows from operations. The free cash flow to net income ratio is positive at 1.19, suggesting that free cash flow exceeds net income, but the overall cash flow position remains weak due to negative operating cash flows.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue4.40M4.40M4.97M11.78M12.97M7.23M
Gross Profit4.40M4.40M4.97M9.57M10.56M5.27M
EBITDA-67.42M-67.42M-147.98M-47.42M-48.06M-23.72M
Net Income-69.02M-69.02M-149.68M-37.91M-37.87M-18.45M
Balance Sheet
Total Assets83.59M83.59M151.40M197.06M147.61M71.81M
Cash, Cash Equivalents and Short-Term Investments21.94M21.94M94.54M153.15M99.89M29.49M
Total Debt10.65M10.65M2.19M553.47K673.43K271.03K
Total Liabilities38.56M38.56M33.14M7.44M8.90M6.79M
Stockholders Equity45.03M45.03M118.25M189.63M138.70M65.02M
Cash Flow
Free Cash Flow-83.12M-90.03M-108.80M-29.78M-30.93M-18.58M
Operating Cash Flow-75.57M-75.57M-101.73M-29.78M-30.67M-13.13M
Investing Cash Flow-12.70M-12.70M-7.25M9.63K-414.16K-5.48M
Financing Cash Flow17.37M17.37M49.43M82.98M101.35M17.99M

Imugene Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.33
Price Trends
50DMA
0.35
Negative
100DMA
0.32
Positive
200DMA
0.53
Negative
Market Momentum
MACD
>-0.01
Negative
RSI
49.40
Neutral
STOCH
45.56
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:IMU, the sentiment is Negative. The current price of 0.33 is above the 20-day moving average (MA) of 0.32, below the 50-day MA of 0.35, and below the 200-day MA of 0.53, indicating a neutral trend. The MACD of >-0.01 indicates Negative momentum. The RSI at 49.40 is Neutral, neither overbought nor oversold. The STOCH value of 45.56 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:IMU.

Imugene Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
56
Neutral
AU$90.43M-9.45-49.72%10.78%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
44
Neutral
AU$166.28M0.66%
41
Neutral
AU$97.88M-42.68%63.46%
41
Neutral
$110.36M-83.09%55.94%
40
Underperform
$145.70M-81.03%-20.79%73.98%
40
Underperform
AU$106.68M-13.09-47.98%700.00%26.88%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:IMU
Imugene
0.33
-1.06
-76.33%
AU:PAR
Paradigm Biopharmaceuticals
0.33
-0.12
-26.97%
AU:ATH
Alterity Therapeutics
0.01
0.00
0.00%
AU:PTX
Prescient Therapeutics Limited
0.09
0.04
104.76%
AU:RCE
Recce Pharmaceuticals Ltd.
0.58
0.07
13.86%
AU:ALA
Arovella Therapeutics Limited
0.08
-0.10
-55.56%

Imugene Corporate Events

Imugene’s Azer-cel CAR T Therapy Shows Promising Results in Phase 1b Trial
Dec 1, 2025

Imugene Limited has announced promising results from its Phase 1b clinical trial of azer-cel, an allogeneic CD19 CAR T therapy for relapsed diffuse large B-cell lymphoma (DLBCL). The trial has achieved an 82% overall response rate, with seven complete and seven partial responses among the patients, many of whom had previously failed multiple lines of therapy. This development highlights the potential of azer-cel in addressing high unmet needs in aggressive blood cancer treatment. The trial is expanding to include CAR T naïve patients with various non-Hodgkin lymphomas, showing meaningful clinical activity and durability of response.

Imugene Collaborates with JW Therapeutics on Innovative Cancer Treatment
Nov 26, 2025

Imugene Limited announced a strategic collaboration with JW Therapeutics to advance the combination of onCARlytics (CF33-CD19) and Carteyva® for treating solid tumors. The collaboration includes a ‘mark and kill’ strategy for refractory solid tumors, potentially enhancing Imugene’s position in the immuno-oncology field. A webinar will be held to discuss this collaboration, indicating its significance for stakeholders and the company’s future operations.

Imugene and JW Therapeutics Collaborate on Novel Cancer Therapy
Nov 26, 2025

Imugene Ltd and JW Therapeutics have announced a strategic collaboration to evaluate a novel combination therapy using Imugene’s onCARlytics oncolytic virus and JW’s CD19 CAR-T cell therapy, Carteyva®, targeting refractory solid tumors. This collaboration will involve preclinical studies and a Phase 1 trial in China, leveraging a ‘mark and kill’ strategy to make solid tumors targetable by CD19-CAR T cells. The initiative aims to generate impactful data efficiently and explore a breakthrough treatment paradigm for solid tumors, ensuring disciplined capital allocation and strategic flexibility.

Imugene AGM Results: Shareholder Dissent and Board Support
Nov 13, 2025

Imugene Limited announced the results of its Annual General Meeting, highlighting a significant shareholder dissent with 30.55% voting against the Remuneration Report, marking a ‘second strike’ under the Corporations Act 2001. Despite this, the Spill Resolution was not passed, with 84.06% voting against it, indicating continued support for the current board and management.

Imugene Issues Disclaimer for Annual General Meeting Presentation
Nov 12, 2025

Imugene Limited has released a disclaimer regarding its presentation for the Annual General Meeting in November 2025. The company emphasizes that the information provided does not constitute personal investment advice and should not be solely relied upon for making investment decisions. Stakeholders are advised to seek professional investment advice, as the presentation does not account for individual investment objectives or financial situations. Imugene also highlights that the presentation is not an offer to sell or solicit securities in jurisdictions where such actions would be unlawful, including the United States.

Imugene Announces Webinar on CAR T Naïve Lymphomas and ASH Presentation
Nov 3, 2025

Imugene Limited announced an upcoming webinar to discuss early efficacy results from their azer-cel Phase 1b trial for CAR T naïve lymphomas and their presentation at the 67th American Society of Hematology Annual Meeting. This initiative reflects Imugene’s commitment to advancing cancer treatment and engaging stakeholders, potentially strengthening its position in the immuno-oncology market.

Imugene’s Azer-cel Selected for Prestigious ASH Presentation
Nov 3, 2025

Imugene Limited announced that its abstract on azer-cel, an allogeneic CD19 CAR T therapy, has been selected for oral presentation at the 67th American Society of Hematology Annual Meeting in Florida. This selection highlights the clinical interest in allogeneic CAR T approaches and provides an opportunity for Imugene to present new insights from their ongoing study on relapsed or refractory large B-cell lymphoma, potentially impacting the company’s industry positioning and stakeholder engagement.

Imugene Issues Shares to Precision Biosciences, Marking Milestone Achievement
Nov 3, 2025

Imugene Limited has issued 19,491,635 fully paid ordinary shares to Precision Biosciences, Inc. as part of a milestone achievement under their License Agreement. This issuance reflects Imugene’s progress in its strategic collaboration with Precision Biosciences, potentially enhancing its market position in the immuno-oncology sector. The move signifies Imugene’s commitment to advancing its clinical and commercial milestones, aligning with its vision to become a leader in the rapidly growing global cancer treatment market.

Imugene Issues Shares to Precision Biosciences Following Milestone Achievement
Nov 3, 2025

Imugene Limited has announced the issuance of 19,491,635 fully paid ordinary shares to Precision Biosciences, Inc., marking the achievement of a significant milestone under their License Agreement dated August 16, 2023. This development is expected to enhance Imugene’s operational capabilities and strengthen its position in the biotechnology sector by advancing its collaborative efforts with Precision Biosciences.

Imugene Achieves 81% Response Rate in CAR T-cell Therapy Trial
Oct 31, 2025

Imugene Limited has announced a significant milestone in its Phase 1b clinical trial of azer-cel, an allogeneic CD19 CAR T-cell therapy, which has achieved an 81% overall response rate in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The trial’s success, including rapid and durable responses, positions Imugene favorably in the immuno-oncology sector, with potential implications for expanding treatment options for rare lymphomas. Additionally, the company has raised approximately $25 million through an institutional placement and share purchase plan, and received a $5.9 million R&D tax refund, bolstering its financial position to support ongoing research and development efforts.

Imugene Reports Promising Results in CAR T-Naïve Lymphoma Trial
Oct 29, 2025

Imugene Limited has announced promising early efficacy results from its Phase 1b trial of azer-cel, an allogeneic CD19 CAR T therapy, in CAR T-naïve patients with various B-cell lymphomas. The trial showed an 83% overall response rate and a 50% complete response rate among the six evaluable patients, with enrolment progressing faster than previous cohorts. This progress highlights the substantial clinical demand and potential for expedited clinical paths, particularly in areas of unmet need.

Imugene’s PD1-Vaxx Colorectal Cancer Trial to Feature at ESMO 2025
Oct 20, 2025

Imugene Limited announced that its PD1-Vaxx colorectal cancer trial will be featured at the ESMO Congress 2025, highlighting its growing international clinical presence. The Neo-POLEM Phase II trial aims to assess the efficacy of PD1-Vaxx, a novel B-cell vaccine, in treating early-stage MSI-high colorectal cancer, potentially offering an alternative to existing monoclonal antibody therapies. The trial, which began recruitment in May 2025, is a collaborative effort involving multiple sites in the UK and Australia, and seeks to improve treatment outcomes for colorectal cancer patients.

Imugene Expands Market Presence with New Securities Quotation
Oct 13, 2025

Imugene Limited has announced the quotation of 2,206 ordinary fully paid securities on the Australian Securities Exchange (ASX). This move is part of the company’s strategy to enhance its financial flexibility and support its ongoing projects in cancer immunotherapy. The issuance of these securities reflects Imugene’s commitment to expanding its market presence and advancing its research and development efforts, potentially benefiting stakeholders through increased investment opportunities.

Imugene Announces 2025 Annual General Meeting and Remuneration Enhancements
Oct 13, 2025

Imugene Limited has announced its 2025 Annual General Meeting, which will address key business matters such as adopting the 2025 Remuneration Report, re-electing directors, and approving equity incentives. The company has made enhancements to its remuneration approach, emphasizing transparency and alignment with performance metrics, and the board intends to forego 50% of equity incentives as a gesture of confidence in challenging capital markets.

Imugene’s Azer-cel CAR T Therapy Shows Promising Results in Phase 1b Trial
Sep 18, 2025

Imugene Limited has announced promising results from its Phase 1b clinical trial of azer-cel, an allogeneic off-the-shelf CD19 CAR T therapy for relapsed diffuse large B-cell lymphoma (DLBCL). The trial has achieved an 81% overall response rate, with 7 complete responses and 6 partial responses among patients who have previously failed multiple lines of therapy. This development highlights the potential of azer-cel in addressing high unmet needs in the treatment of aggressive blood cancers and expands its application to other lymphoma types. The trial is actively enrolling patients in the U.S. and Australia, with additional updates expected in the coming months.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Nov 06, 2025