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Alterity Therapeutics Ltd. (AU:ATH)
ASX:ATH

Alterity Therapeutics (ATH) AI Stock Analysis

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AU

Alterity Therapeutics

(Sydney:ATH)

Rating:51Neutral
Price Target:
AU$0.00
▼(-100.00%Downside)
The overall score reflects significant financial challenges, with Alterity Therapeutics Ltd. facing substantial net losses and negative cash flows despite a strong equity position. Technical indicators provide some mild positive signals, but the lack of profitability severely impacts valuation appeal.

Alterity Therapeutics (ATH) vs. iShares MSCI Australia ETF (EWA)

Alterity Therapeutics Business Overview & Revenue Model

Company DescriptionAlterity Therapeutics Ltd. (ATH) is a biotechnology company focused on developing therapeutic products to treat neurodegenerative diseases. The company operates within the biopharmaceutical sector, with its core focus on creating innovative treatments for conditions such as Parkinson's disease and other neurological disorders. Alterity Therapeutics leverages its proprietary drug development platform to discover and advance novel compounds that target the underlying causes of these diseases.
How the Company Makes MoneyAlterity Therapeutics makes money primarily through the development and commercialization of its pharmaceutical products. Revenue streams include funding from research and development collaborations, partnerships, and potential licensing agreements with larger pharmaceutical companies. Additionally, the company may receive governmental grants and subsidies intended to support research in neurodegenerative disease treatments. As Alterity Therapeutics moves its products through clinical trials and towards regulatory approval, future revenue is anticipated from product sales and royalties. Significant partnerships with research institutions and healthcare organizations can also contribute to its earnings.

Alterity Therapeutics Financial Statement Overview

Summary
Alterity Therapeutics Ltd. is struggling with profitability and cash flow, despite maintaining a strong equity position. Revenue has slightly increased, but substantial net losses and negative cash flows persist. The company shows resilience with low leverage, but profitability and cash flow generation remain critical concerns.
Income Statement
45
Neutral
Alterity Therapeutics Ltd. shows a decline in revenue growth with a 2.6% year-over-year increase from 2023 to 2024, following a previous decline. The gross profit margin remains high at around 94.7%, but the company faces significant net losses with a net profit margin of -475.8% in 2024. The EBIT and EBITDA margins are also negative, indicating operational challenges.
Balance Sheet
55
Neutral
The balance sheet highlights Alterity's strong equity position, with an equity ratio of 71.8% in 2024. However, the company faces consistent net losses, impacting return on equity, which is negative. The debt-to-equity ratio remains low at 0.01, reflecting minimal leverage.
Cash Flow
40
Negative
Negative free cash flow growth is evident, as free cash flow improved slightly but remains negative. The operating cash flow to net income ratio is positive, indicating some ability to manage cash despite losses. However, the free cash flow to net income ratio is negative, highlighting ongoing cash management challenges.
Breakdown
TTMJun 2024Jun 2023Jun 2022Jun 2021Jun 2020
Income StatementTotal Revenue
3.72M4.02M3.92M5.12M4.34M0.00
Gross Profit
3.59M3.80M3.63M4.76M3.98M-112.43K
EBIT
-22.59M-19.60M-14.64M-15.50M-15.18M-10.41M
EBITDA
-22.14M-19.57M-17.51M-17.39M-19.36M-13.34M
Net Income Common Stockholders
-19.79M-19.12M-13.81M-12.85M-15.31M-9.70M
Balance SheetCash, Cash Equivalents and Short-Term Investments
4.54M12.64M15.77M34.81M28.12M9.20M
Total Assets
10.55M19.22M27.32M41.36M33.59M13.30M
Total Debt
105.83K159.04K210.38K117.49K65.65K33.75K
Net Debt
-4.43M-12.48M-15.56M-34.69M-28.05M-9.16M
Total Liabilities
2.76M5.43M4.50M5.89M3.12M2.76M
Stockholders Equity
7.79M13.80M22.81M35.47M30.47M10.55M
Cash FlowFree Cash Flow
-16.47M-12.61M-20.04M-12.43M-17.34M-9.45M
Operating Cash Flow
-16.47M-12.61M-20.04M-12.34M-17.33M-9.43M
Investing Cash Flow
-722.00-5.72K-36.46K-89.15K-10.47K-16.74K
Financing Cash Flow
8.46M9.22M124.34K16.30M36.69M3.98M

Alterity Therapeutics Peers Comparison

Overall Rating
UnderperformOutperform
Sector (54)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
AUEZZ
79
Outperform
AU$85.86M8.8545.86%2.20%71.65%152.89%
54
Neutral
$5.38B3.31-45.11%3.29%16.82%0.04%
AUATH
51
Neutral
$109.53M-154.88%20.00%
AURCE
46
Neutral
AU$92.28M
-33.01%
AUIMU
41
Neutral
$119.47M-99.05%-34.09%
AUPAR
40
Underperform
AU$116.83M-46.65%96.20%80.90%
AUALA
40
Underperform
AU$89.97M-85.35%315.11%51.16%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:ATH
Alterity Therapeutics
0.01
<0.01
10.00%
AU:IMU
Imugene Limited
0.02
-0.04
-74.14%
AU:PAR
Paradigm Biopharmaceuticals
0.30
0.06
25.53%
AU:EZZ
EZZ Life Science Holdings Ltd.
1.74
0.58
50.00%
AU:RCE
Recce Pharmaceuticals Ltd.
0.34
-0.20
-37.04%
AU:ALA
Arovella Therapeutics Limited
0.08
-0.06
-42.86%

Alterity Therapeutics Corporate Events

BNY Mellon Increases Stake in Alterity Therapeutics
May 22, 2025

The Bank of New York Mellon Corporation (BNYMC) has increased its substantial holding in Alterity Therapeutics Limited, now holding a 27.03% voting power compared to the previous 26.01%. This change indicates a growing interest and confidence in Alterity’s operations, potentially impacting the company’s market positioning and stakeholder relations.

Alterity Therapeutics Showcases Promising MSA Treatment Advances
May 12, 2025

Alterity Therapeutics announced significant findings from its clinical programs at the 2025 International MSA Congress, highlighting the efficacy of its ATH434 treatment in reducing disease severity and improving symptoms in MSA patients. The introduction of the MSA Atrophy Index as a diagnostic and monitoring tool, along with insights from the bioMUSE study, underscores Alterity’s commitment to advancing MSA treatment and enhancing diagnostic capabilities, potentially impacting patient care and clinical practices.

BNY Mellon Increases Stake in Alterity Therapeutics
May 11, 2025

The Bank of New York Mellon Corporation (BNYMC) has increased its voting power in Alterity Therapeutics Limited from 24.95% to 26.01%, as of May 8, 2025. This change in substantial holding indicates a strengthened position for BNYMC in the company, potentially impacting Alterity’s strategic decisions and shareholder dynamics.

Alterity Therapeutics to Showcase MSA Research at 2025 Congress
May 7, 2025

Alterity Therapeutics announced its participation in the 2025 International MSA Congress, where it will present multiple oral and poster presentations on its clinical programs for Multiple System Atrophy (MSA). The presentations will highlight the Phase 2 data for ATH434, which has shown significant clinical efficacy and safety in treating MSA. The company’s involvement in the congress underscores its commitment to advancing MSA research and care, further supported by the recent Fast Track Designation for ATH434 by the US FDA.

Alterity Therapeutics’ ATH434 Receives FDA Fast Track Designation for MSA Treatment
May 5, 2025

Alterity Therapeutics announced that the U.S. FDA has granted Fast Track designation for its lead candidate, ATH434, aimed at treating Multiple System Atrophy (MSA). This designation is expected to accelerate the development and review process of ATH434, highlighting its potential to meet the high unmet need for MSA treatments. The Fast Track status allows Alterity to engage more frequently with the FDA, potentially speeding up the path to approval. The company has demonstrated ATH434’s efficacy and safety in Phase 2 trials, showing significant improvements in clinical outcomes for MSA patients.

Alterity Therapeutics Reports Positive Phase 2 Trial Results for MSA Treatment
Apr 28, 2025

Alterity Therapeutics announced promising results from their ATH434-201 Phase 2 clinical trial at the European MSA Symposium. The trial demonstrated that ATH434 significantly reduced disease severity in MSA patients, with improvements in daily living activities and motor performance. ATH434 was well tolerated, showing potential for further development in treating MSA, a rare neurodegenerative disorder. The study’s positive outcomes, including target engagement and brain volume preservation, support the continued advancement of ATH434, which has been granted Orphan Drug Designation by the U.S. FDA and the European Commission.

Alterity Therapeutics Reveals Top Option Holders
Apr 22, 2025

Alterity Therapeutics Limited has released a report detailing the top 20 holders of its listed options, which are set to expire on February 26, 2027, with a price of $0.028. The report highlights that UBS Nominees Pty Ltd holds the largest percentage of these options at 29.25%, followed by Citicorp Nominees Pty Limited with 18.11%. This information provides insights into the distribution of holdings among major investors, which could have implications for the company’s market strategy and investor relations.

Alterity Therapeutics Announces New Securities Quotation
Apr 22, 2025

Alterity Therapeutics Limited announced the quotation of a new class of options on the Australian Securities Exchange, with an exercise price of $0.028 and an expiration date in February 2027. This move signifies a strategic financial decision aimed at enhancing the company’s capital structure, potentially impacting its market positioning and providing stakeholders with new investment opportunities.

Alterity Therapeutics Issues Caution on Forward-Looking Statements
Apr 22, 2025

Alterity Therapeutics Ltd. has released a presentation that may contain forward-looking statements in accordance with US Securities Laws. These statements involve risks and uncertainties that could cause actual results to differ materially from expectations, highlighting the importance of consulting their 2024 Form 20-F for detailed risk factors.

Alterity Therapeutics Announces New Options Prospectus to Bolster Financial Strategy
Apr 17, 2025

Alterity Therapeutics Ltd. has announced a prospectus offering new options to selected participants, including a placement offer and a broker offer. The options, which have an exercise price of A$0.028 and expire in February 2027, aim to raise capital and potentially strengthen the company’s financial position, impacting its future operations and market strategy.

Alterity Therapeutics Unveils Promising Phase 2 Study Results for MSA Treatment
Apr 10, 2025

Alterity Therapeutics Ltd. has announced topline data from a Phase 2 study of ATH434, a treatment for Multiple System Atrophy (MSA), presented at the American Academy of Neurology Annual Meeting in 2025. The study was a randomized, double-blind, placebo-controlled trial, indicating a significant step in the company’s research efforts, potentially impacting its position in the neurology field and offering new hope for stakeholders involved in MSA treatment development.

Alterity Therapeutics Director Increases Stake Through Share Acquisition
Apr 9, 2025

Alterity Therapeutics Ltd. announced a change in the director’s interest, with Peter Marks acquiring 1,818,182 fully paid ordinary shares through a placement at $0.011 per share. This acquisition reflects an increase in Marks’ stake in the company, potentially signaling confidence in Alterity’s strategic direction and future prospects, which could influence investor sentiment and market perception.

Regal Funds Management Becomes Substantial Holder in Alterity Therapeutics
Apr 8, 2025

Alterity Therapeutics Ltd has announced that Regal Funds Management Pty Ltd and its associates have become substantial holders in the company as of April 4, 2025. Regal Funds Management now holds a significant voting power with 1,255,948,179 ordinary shares, representing a substantial interest in Alterity Therapeutics. This development indicates a strategic move by Regal Funds Management, potentially impacting Alterity’s market positioning and stakeholder dynamics.

BNY Mellon Reduces Stake in Alterity Therapeutics
Apr 7, 2025

The Bank of New York Mellon Corporation (BNYMC) has reported a change in its substantial holding in Alterity Therapeutics Ltd., with its voting power decreasing from 33.96% to 24.95%. This shift in voting power could impact BNYMC’s influence over company decisions, potentially affecting Alterity’s strategic direction and stakeholder interests.

Alterity Therapeutics Completes A$38.79M Placement to Advance Neurodegenerative Disease Treatments
Apr 7, 2025

Alterity Therapeutics has successfully completed a two-tranche placement, raising A$38.79 million, with significant participation from its leadership and board. The funds will be used to accelerate the regulatory and development activities for its lead candidate ATH434, which has shown positive results in Phase 2 trials for MSA and has received Orphan Drug Designation in the U.S. and Europe. This financial boost is expected to enhance Alterity’s position in the biotechnology industry, allowing it to further its research and development efforts in neurodegenerative diseases.

Alterity Therapeutics Issues Over 2.4 Billion Shares in Compliance with Corporations Act
Apr 7, 2025

Alterity Therapeutics Ltd. announced the issuance of 2,470,521,806 fully paid ordinary shares without disclosure under Part 6D.2 of the Corporations Act, as permitted by section 708A(5)(e). The company has confirmed compliance with relevant provisions of the Corporations Act and stated that there is no excluded information to disclose, ensuring transparency and adherence to regulatory requirements.

Alterity Therapeutics Announces Quotation of New Securities
Apr 7, 2025

Alterity Therapeutics Limited has announced the quotation of over 2.47 billion fully paid ordinary securities on the Australian Securities Exchange. This move is part of previously announced transactions and is expected to enhance the company’s financial flexibility, potentially impacting its market positioning and providing opportunities for growth and development in its therapeutic areas.

Alterity Therapeutics to Present Promising ATH434 Phase 2 Results at Neurology Meeting
Apr 3, 2025

Alterity Therapeutics announced positive results from their ATH434 Phase 2 clinical trial, which will be presented at the American Academy of Neurology Annual Meeting. The trial showed significant improvements in patients with early-stage Multiple System Atrophy (MSA), with ATH434 demonstrating efficacy in reducing disability and improving motor performance. The use of wearable sensors in the study indicated increased activity levels in patients, and the drug showed potential in reducing iron accumulation in the brain, suggesting a promising impact on the treatment of MSA.

Alterity Therapeutics Secures Shareholder Approval for Key Resolutions
Mar 31, 2025

Alterity Therapeutics Ltd. held an Extraordinary General Meeting where several resolutions regarding the issuance of shares, options, and securities were passed with significant support. The approval of these resolutions is expected to enhance the company’s financial flexibility and strategic positioning, potentially benefiting stakeholders by facilitating future growth and development initiatives.

Alterity Therapeutics to Quote New Securities on ASX
Mar 14, 2025

Alterity Therapeutics Limited has announced the application for the quotation of new securities on the Australian Securities Exchange (ASX). This move involves the issuance of 161 fully paid ordinary shares, reflecting the company’s ongoing efforts to enhance its financial standing and operational capabilities. The announcement is part of Alterity’s strategic initiatives to strengthen its market position and support its research and development activities, potentially impacting its stakeholders by providing additional resources for advancing its therapeutic projects.

JPMorgan Chase Acquires Significant Stake in Alterity Therapeutics
Mar 13, 2025

JPMorgan Chase & Co. and its affiliates have become substantial holders in Alterity Therapeutics Ltd, acquiring a 5.13% voting power in the company. This acquisition signifies a notable investment by a major financial institution, potentially impacting Alterity Therapeutics’ market position and stakeholder interests.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.