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Paradigm Biopharmaceuticals Ltd. (AU:PAR)
ASX:PAR
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Paradigm Biopharmaceuticals (PAR) AI Stock Analysis

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AU:PAR

Paradigm Biopharmaceuticals

(Sydney:PAR)

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Neutral 42 (OpenAI - 5.2)
Rating:42Neutral
Price Target:
AU$0.22
▼(-34.55% Downside)
Action:ReiteratedDate:04/10/26
The score is weighed down primarily by weak financial performance (minimal revenue, persistent losses, and ongoing cash burn), with only the low-debt balance sheet providing partial support. Technicals further pressure the score due to a clear downtrend and negative momentum signals. Valuation is difficult to anchor because earnings are negative and there is no dividend yield data.
Positive Factors
Low leverage balance sheet
Extremely low debt relative to equity provides durable financial flexibility: it reduces refinancing and interest-rate risk, gives management optionality to fund R&D or commercialization with less near-term pressure, and preserves runway when cash flows are weak.
Negative Factors
Persistent cash burn
Consistent negative operating and free cash flow implies ongoing reliance on external financing to sustain operations. Over months, this increases dilution or leverage risk, constrains strategic investments, and leaves the company vulnerable if capital markets tighten or fundraising terms worsen.
Read all positive and negative factors
Positive Factors
Negative Factors
Low leverage balance sheet
Extremely low debt relative to equity provides durable financial flexibility: it reduces refinancing and interest-rate risk, gives management optionality to fund R&D or commercialization with less near-term pressure, and preserves runway when cash flows are weak.
Read all positive factors

Paradigm Biopharmaceuticals (PAR) vs. iShares MSCI Australia ETF (EWA)

Paradigm Biopharmaceuticals Business Overview & Revenue Model

Company Description
Paradigm Biopharmaceuticals Limited, a drug repurposing company, engages in the research and development of therapeutic products for human use in Australia. It offers pentosan polysulfate sodium drugs in the injectable form for the treatment of os...
How the Company Makes Money
Paradigm Biopharmaceuticals makes money primarily by commercialising pharmaceutical products: generating revenue from sales of its prescription medicines to healthcare customers via distribution channels (e.g., wholesalers/pharmacies/hospitals dep...

Paradigm Biopharmaceuticals Financial Statement Overview

Summary
Income statement quality is weak with minimal/volatile revenue and deeply negative profitability, despite a meaningful net loss narrowing in FY2025. Cash flow remains consistently negative (ongoing cash burn), though FY2025 outflows improved sharply. The balance sheet is a relative strength with very low leverage, but declining equity and strongly negative ROE indicate continued value erosion.
Income Statement
12
Very Negative
Balance Sheet
66
Positive
Cash Flow
24
Negative
BreakdownTTMJun 2025Jun 2024Jun 2023Jun 2022Jun 2021
Income Statement
Total Revenue60.57K52.12K65.80K46.76K79.22K20.55K
Gross Profit-97.57K-19.89K56.81K-18.83K-64.53K-78.59K
EBITDA-40.72M-25.25M-64.54M-59.06M-46.82M-42.40M
Net Income-36.09M-18.77M-58.65M-51.91M-39.25M-34.30M
Balance Sheet
Total Assets23.15M24.57M27.39M67.07M50.69M84.79M
Cash, Cash Equivalents and Short-Term Investments14.66M16.82M17.87M56.38M39.72M71.08M
Total Debt1.01M5.48K239.33K341.67K616.67K751.84K
Total Liabilities17.16M3.39M3.58M13.39M8.38M6.52M
Stockholders Equity6.00M21.18M23.81M53.68M42.31M78.27M
Cash Flow
Free Cash Flow-7.77M-15.99M-65.94M-45.19M-32.21M-34.96M
Operating Cash Flow-27.42M-15.99M-65.94M-45.19M-32.21M-34.93M
Investing Cash Flow-567.20K46.20K0.000.000.00668.37K
Financing Cash Flow18.17M14.99M28.18M62.53M70.12K1.00M

Paradigm Biopharmaceuticals Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.33
Price Trends
50DMA
0.26
Negative
100DMA
0.30
Negative
200DMA
0.33
Negative
Market Momentum
MACD
-0.01
Positive
RSI
38.45
Neutral
STOCH
16.23
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:PAR, the sentiment is Negative. The current price of 0.33 is above the 20-day moving average (MA) of 0.25, above the 50-day MA of 0.26, and above the 200-day MA of 0.33, indicating a bearish trend. The MACD of -0.01 indicates Positive momentum. The RSI at 38.45 is Neutral, neither overbought nor oversold. The STOCH value of 16.23 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:PAR.

Paradigm Biopharmaceuticals Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
AU$94.92M-2.00-131.13%456.50%-457.14%
47
Neutral
AU$84.66M-3.83-24.81%26.64%
47
Neutral
AU$246.16M-5.17-83.97%1271.12%36.87%
43
Neutral
AU$140.07M-4.28-134.14%10.91%
42
Neutral
AU$97.13M-1.51-265.55%-20.79%73.98%
41
Neutral
AU$150.38M-2.84279.21%0.66%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:PAR
Paradigm Biopharmaceuticals
0.23
-0.06
-22.41%
AU:ATX
Amplia Therapeutics
0.17
0.11
217.31%
AU:ACW
Actinogen Medical
0.04
0.01
33.33%
AU:DXB
Dimerix Limited
0.40
>-0.01
-1.25%
AU:BOT
Botanix Pharmaceuticals Limited
0.04
-0.36
-90.63%
AU:RCE
Recce Pharmaceuticals Ltd.
0.57
0.28
96.55%

Paradigm Biopharmaceuticals Corporate Events

Paradigm Biopharmaceuticals Seeks ASX Quotation for 6.86 Million New Shares
Apr 8, 2026
Paradigm Biopharmaceuticals Limited has applied for quotation on the ASX of 6,864,326 new fully paid ordinary shares, with an issue date of 8 April 2026. The new securities arise from the exercise or conversion of options or other convertible secu...
Paradigm partners with City St George’s to probe osteoarthritis bone lesions
Apr 2, 2026
Paradigm Biopharmaceuticals has entered a 12‑month research collaboration with City St George’s, University of London, a major UK centre for musculoskeletal and pain research, to study bone marrow lesions in osteoarthritis. The project...
Paradigm Reaches 50% Enrolment in Global Phase 3 Osteoarthritis Trial
Mar 30, 2026
Paradigm Biopharmaceuticals has reached 50% patient enrolment in its global PARA_OA_012 Phase 3 osteoarthritis trial, marking a key operational milestone as dosing of all participants required for the interim analysis dataset has commenced. The st...
Paradigm Expands Global Phase 3 Osteoarthritis Trial to Hong Kong and Moldova
Mar 19, 2026
Paradigm Biopharmaceuticals has activated a new clinical trial site in Hong Kong for its global Phase 3 study of injectable pentosan polysulfate sodium in patients with knee osteoarthritis, with screening now underway at the Hong Kong Centre for C...
Paradigm Biopharmaceuticals Seeks ASX Quotation for 5.65 Million New Shares
Mar 16, 2026
Paradigm Biopharmaceuticals has applied for quotation on the ASX of 5,653,700 new fully paid ordinary shares, with an issue date of March 16, 2026. The issuance of these additional securities expands the company’s quoted share capital, poten...
Paradigm Biopharmaceuticals Widens Half-Year Loss on Intensified Phase 3 Investment
Feb 26, 2026
Paradigm Biopharmaceuticals reported a net loss before tax of A$23.2 million for the half-year ended 31 December 2025, a sharp increase from the prior period’s A$5.9 million loss, as it intensified investment in late-stage clinical developme...
Paradigm Biopharmaceuticals Updates Market on Director Paul Rennie’s Equity Holdings
Feb 23, 2026
Paradigm Biopharmaceuticals has disclosed changes in director Paul Rennie’s interests in the company’s securities, detailing movements across fully paid ordinary shares, listed options, performance rights and unlisted piggyback options...
Paradigm Biopharmaceuticals Updates Market on Director Option Lapse
Feb 23, 2026
Paradigm Biopharmaceuticals has disclosed a change in director Matthew Fry’s interests, reporting the lapse of 354,958 listed options exercisable at $0.65 that expired on 11 February 2026. Following the lapse, Fry continues to hold 1,419,830...
Paradigm’s PPS Shows Sustained Clinical and Structural Benefits in Canine Osteoarthritis Study
Feb 11, 2026
Paradigm Biopharmaceuticals announced that a Paradigm-supported study of pentosan polysulfate sodium in dogs with naturally occurring osteoarthritis has been published in the peer-reviewed journal PLOS One. The collaborative trial with the Univers...
Paradigm Strikes AVet Licensing Deal for Novel Oral Veterinary Osteoarthritis Drug
Feb 8, 2026
Paradigm Biopharmaceuticals has signed a binding term sheet with AVet Health to co-develop and license an oral combination of pentosan polysulfate sodium and a COX-2 inhibitor for osteoarthritis in companion animals in Australia and New Zealand. A...
Paradigm Biopharmaceuticals Director Converts Options Into Shares
Feb 3, 2026
Paradigm Biopharmaceuticals has disclosed a change in the interests of director Paul Rennie, who has converted 153,265 listed options into fully paid ordinary shares. The transaction, executed on 3 February 2026 for a consideration of $99,622.25, ...
Paradigm Biopharmaceuticals Seeks ASX Quotation for Additional Ordinary Shares
Feb 3, 2026
Paradigm Biopharmaceuticals has applied to the ASX for quotation of 176,880 new ordinary fully paid shares following the exercise or conversion of existing options or other convertible securities, with an issue date of 3 February 2026. The modest ...
Paradigm Biopharmaceuticals Seeks ASX Quotation for Additional Ordinary Shares
Jan 30, 2026
Paradigm Biopharmaceuticals has applied for quotation on the ASX of 10,037 new fully paid ordinary shares, following the exercise or conversion of existing options or other convertible securities. The modest increase in quoted securities reflects ...
Paradigm Expands Global Phase 3 Knee Osteoarthritis Trial as Peer-Reviewed Data Bolster iPPS Case
Jan 30, 2026
Paradigm Biopharmaceuticals reported continued operational progress in the December 2025 quarter, advancing its global Phase 3 PARA_OA_012 trial of injectable pentosan polysulfate sodium for knee osteoarthritis pain, with most sites in Australia a...
Paradigm Biopharmaceuticals Seeks ASX Quotation for Additional Ordinary Shares
Jan 27, 2026
Paradigm Biopharmaceuticals has applied for quotation on the ASX of 35,544 new ordinary fully paid shares, to be issued on 27 January 2026 following the exercise or conversion of existing options or other convertible securities. The modest share i...
Paradigm Biopharmaceuticals Seeks ASX Quotation for Nearly 5 Million New Shares
Jan 16, 2026
Paradigm Biopharmaceuticals has applied for quotation on the ASX of 4,940,912 new fully paid ordinary shares, following the exercise or conversion of options or other convertible securities. The issuance and listing of these additional shares mode...
Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Apr 10, 2026