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Genetic Signatures Ltd. (AU:GSS)
ASX:GSS
Australian Market

Genetic Signatures Ltd. (GSS) AI Stock Analysis

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AU:GSS

Genetic Signatures Ltd.

(Sydney:GSS)

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Underperform 40 (OpenAI - 5.2)
Rating:40Underperform
Price Target:
AU$0.17
▼(-30.83% Downside)
The score is held down primarily by weak financial performance (ongoing losses and negative operating/free cash flow). Technicals also remain poor with price below key moving averages and negative momentum indicators. Valuation provides little support due to a negative P/E and no dividend yield data.
Positive Factors
Proprietary 3base technology
Ownership of the proprietary 3base™ chemistry provides a durable product differentiation for multiplex PCR panels. That IP supports unique assay design, raises technical barriers to entry, and underpins long-term laboratory partnerships and product stickiness across geographies.
Consumables-driven recurring revenue
The business model centres on recurring consumable sales to clinical labs, which scale with testing volumes and installed bases. This consumables model can generate stable, repeatable revenue over time as adoption expands, supporting margin improvement once fixed costs are covered.
Very low financial leverage
A debt-to-equity of ~0.016 gives the company low refinancing and interest burden, preserving financial flexibility. That strengthens its ability to fund regulatory approvals, commercialization and R&D over months without high fixed finance costs that could constrain strategic investment.
Negative Factors
Persistent negative profitability
Consistent negative net, EBIT and EBITDA margins indicate the company is not yet operationally profitable. This limits internal funding for growth, increases reliance on external capital, and raises the execution threshold needed to reach sustainable margins over the medium term.
Negative operating and free cash flow
Ongoing negative operating and free cash flow show the business burns cash to operate. Even with recent slight FCF improvement, cash generation is insufficient to self-fund expansion, increasing financing risk and potentially slowing commercialization and market penetration.
Revenue volatility due to seasonality
Demand depends on seasonality and outbreak cycles, creating lumpy, unpredictable volumes. That structural volatility complicates forecasting, capacity utilization and distributor inventory planning, making sustained revenue growth and margin stability harder to achieve without broader menu adoption.

Genetic Signatures Ltd. (GSS) vs. iShares MSCI Australia ETF (EWA)

Genetic Signatures Ltd. Business Overview & Revenue Model

Company DescriptionGenetic Signatures Limited operates as a molecular diagnostic (MDx) company in Australia, the Asia Pacific, the Americas, Europe, the Middle East, Israel, and Africa. It designs and manufactures a suite of real-time polymerase chain reaction-based products for detection of infectious diseases under the EasyScreen brand name. The company also provides MDx 3Base platform technology that enables hospital and pathology laboratories to screen for a range of infectious pathogens. In addition, it offers detection kits for gastrointestinal infections, respiratory, sexual health, anti-microbial resistance, meningitis, and tropical disease. The company was incorporated in 2001 and is headquartered in Newtown, Australia.
How the Company Makes MoneyGenetic Signatures Ltd. generates revenue through the sale of its diagnostic tests and related products to laboratories and healthcare providers. The company employs a direct sales model as well as partnerships with distributors to reach a wider market. Key revenue streams come from the sales of its assays, which are used for pathogen detection in clinical diagnostics. Additionally, GSS may earn revenue through licensing agreements or collaborations with other companies in the healthcare and biotechnology sectors, enhancing its market presence and product offerings. The company’s growth is also supported by ongoing developments in molecular diagnostics and increased demand for rapid testing solutions.

Genetic Signatures Ltd. Financial Statement Overview

Summary
Financial profile is weak: profitability remains negative (net/EBIT/EBITDA margins), and operating/free cash flow are negative. Offsetting factors include low leverage (very low debt-to-equity) and a recent uptick in revenue growth, but sustained earnings and cash generation are still lacking.
Income Statement
35
Negative
Genetic Signatures Ltd. has experienced fluctuating revenue growth, with a recent positive trend of 8.45% in the latest year. However, profitability remains a significant concern, as indicated by negative net profit margins and EBIT margins over the past years. The company has struggled to maintain positive gross profit margins, and the consistent negative EBIT and EBITDA margins highlight ongoing operational challenges.
Balance Sheet
45
Neutral
The company's balance sheet shows a strong equity position with a low debt-to-equity ratio of 0.0158, indicating minimal leverage. However, the return on equity is negative, reflecting the company's inability to generate profits from its equity base. The equity ratio remains stable, suggesting a solid capital structure despite profitability issues.
Cash Flow
40
Negative
Cash flow analysis reveals a challenging situation, with negative operating and free cash flows. Although there is a slight improvement in free cash flow growth, the operating cash flow to net income ratio is negative, indicating cash flow issues. The free cash flow to net income ratio is above 1, suggesting that free cash flow is relatively better than net income, but overall cash generation remains weak.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue15.90M15.90M9.77M16.94M35.42M28.28M
Gross Profit-2.39M7.78M4.31M-12.74M7.21M4.27M
EBITDA-15.87M-16.08M-19.82M-13.14M4.70M3.22M
Net Income-20.10M-20.10M-17.86M-14.05M3.06M1.76M
Balance Sheet
Total Assets54.63M54.63M67.29M49.08M59.65M54.05M
Cash, Cash Equivalents and Short-Term Investments31.30M31.30M36.25M16.35M36.90M30.12M
Total Debt791.00K791.00K1.22M0.0034.00K399.00K
Total Liabilities4.54M4.54M6.18M6.16M4.85M4.71M
Stockholders Equity50.09M50.09M61.10M42.91M54.80M49.34M
Cash Flow
Free Cash Flow-12.94M-13.19M-14.91M-20.55M6.82M-784.00K
Operating Cash Flow-12.29M-12.29M-10.12M-12.45M9.81M4.20M
Investing Cash Flow-24.30M-24.30M-4.79M-8.09M-2.99M-4.98M
Financing Cash Flow7.79M7.79M34.81M-23.00K-101.00K-190.00K

Genetic Signatures Ltd. Technical Analysis

Technical Analysis Sentiment
Negative
Last Price0.24
Price Trends
50DMA
0.25
Negative
100DMA
0.26
Negative
200DMA
0.34
Negative
Market Momentum
MACD
-0.02
Positive
RSI
14.35
Positive
STOCH
2.74
Positive
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:GSS, the sentiment is Negative. The current price of 0.24 is above the 20-day moving average (MA) of 0.21, below the 50-day MA of 0.25, and below the 200-day MA of 0.34, indicating a bearish trend. The MACD of -0.02 indicates Positive momentum. The RSI at 14.35 is Positive, neither overbought nor oversold. The STOCH value of 2.74 is Positive, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Negative sentiment for AU:GSS.

Genetic Signatures Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
64
Neutral
AU$51.74M27.4698.18%11.93%2.39%
53
Neutral
AU$50.59M-13.18-501.54%56.42%
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
45
Neutral
AU$44.17M-6.06-97.79%23.85%
42
Neutral
AU$154.53M-14.60-111.23%12.96%40.81%
40
Underperform
AU$37.48M-1.83-36.16%62.81%16.37%
38
Underperform
AU$51.38M-5.78-37.78%2.33%12.50%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:GSS
Genetic Signatures Ltd.
0.17
-0.45
-73.39%
AU:BDX
BCAL Diagnostics Limited
0.12
0.02
20.00%
AU:RHY
Rhythm Biosciences Ltd.
0.17
0.08
82.80%
AU:LDX
Lumos Diagnostics Holdings Ltd.
0.24
0.21
683.33%
AU:CTE
Cryosite Limited
1.06
0.32
43.24%
AU:IIQ
Inoviq Ltd
0.36
-0.10
-21.74%

Genetic Signatures Ltd. Corporate Events

Genetic Signatures Posts Solid Cash Position as International GI Diagnostics Rollout Gains Traction
Jan 19, 2026

Genetic Signatures reported unaudited second-quarter FY26 sales of $3.3 million, reflecting a seasonal downturn in respiratory testing in Australia, with revenue contributions now coming from Australia, EMEA and the US and a rising share from international markets. Customer receipts reached $4.6 million and net operating cash inflow was $1.8 million, bolstered by an Australian R&D tax incentive, leaving the company with a strong total cash and term deposit position of $29.7 million at 31 December 2025 to fund ongoing operations and development. Operationally, the company advanced implementation of its EasyScreen™ Gastrointestinal Parasite Detection Kit at three initial US customer sites that are now acting as reference centres to drive further adoption, while in the UK its gastrointestinal test kits are gaining momentum with National Health Service trusts, supported by positive clinical data and increased usage in infection control and outbreak prevention. The company also continued development of an automated, high-throughput integrated instrument and software platform, including procurement of a non-customised instrument to expand its 3base® infectious disease testing menu, positioning it for future product launches and potential growth in key international markets.

The most recent analyst rating on (AU:GSS) stock is a Sell with a A$0.22 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Announces CEO Departure and Leadership Transition
Dec 15, 2025

Genetic Signatures Limited announced the upcoming departure of CEO Allison Rossiter, who will leave in February 2026 to join a global pharmaceutical company. The company is actively searching for a new CEO and has interim leadership plans in place to ensure continuity. The leadership transition is seen as an opportunity to strengthen the management team and focus on advancing U.S. market opportunities. The recruitment for a new CFO is also underway, highlighting a period of strategic leadership changes aimed at enhancing the company’s capabilities and market positioning.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Announces Director’s Acquisition of Restricted Rights
Nov 24, 2025

Genetic Signatures Limited announced a change in the director’s interest, with Anne Lockwood acquiring 250,000 Restricted Rights as approved at the company’s Annual General Meeting. This change reflects the company’s ongoing commitment to align its leadership’s interests with its strategic goals, potentially impacting its governance and stakeholder relations positively.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Ltd. Announces Cessation of Securities
Nov 21, 2025

Genetic Signatures Ltd. announced the cessation of 150,000 securities due to the lapse of conditional rights, as the conditions were not met or became incapable of being satisfied. This announcement may impact the company’s capital structure, potentially affecting investor perceptions and market positioning.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Ltd Announces 2025 AGM Results
Nov 17, 2025

Genetic Signatures Ltd held its 2025 Annual General Meeting, where resolutions were put to shareholders, resulting in the re-election of directors and approval of remuneration-related resolutions. These outcomes indicate continued support for the company’s leadership and strategic direction, potentially impacting its market positioning and stakeholder confidence positively.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Announces CFO Resignation
Nov 10, 2025

Genetic Signatures Ltd announced the resignation of its Chief Financial and Operating Officer, Karl Pechmann, effective January 30, 2026. Pechmann has been instrumental in enhancing the company’s financial management and operational performance since joining in June 2023. The company has initiated a search for his successor to ensure continued operational stability. CEO Allison Rossiter praised Pechmann’s contributions, noting his leadership during challenging times and his role in positioning the company for future growth.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Ltd. Issues Performance Rights to Boost Employee Engagement
Nov 6, 2025

Genetic Signatures Ltd. announced the issuance of 1,016,859 performance rights as part of an employee incentive scheme. This move is expected to align employee interests with company goals, potentially enhancing productivity and commitment, and may positively impact the company’s market position and stakeholder value.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Genetic Signatures Updates CEO Remuneration Package
Nov 6, 2025

Genetic Signatures Ltd has updated the remuneration for its CEO, Allison Rossiter, with a new base salary of A$515,000 per annum and a long-term incentive plan involving performance rights. These changes, effective from October 2025, are part of a board review and aim to align the CEO’s compensation with long-term service and performance goals.

The most recent analyst rating on (AU:GSS) stock is a Hold with a A$0.50 price target. To see the full list of analyst forecasts on Genetic Signatures Ltd. stock, see the AU:GSS Stock Forecast page.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Jan 23, 2026