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Rhythm Biosciences Ltd. (AU:RHY)
ASX:RHY
Australian Market

Rhythm Biosciences Ltd. (RHY) AI Stock Analysis

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AU:RHY

Rhythm Biosciences Ltd.

(Sydney:RHY)

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Neutral 45 (OpenAI - 5.2)
Rating:45Neutral
Price Target:
AU$0.13
▼(-5.71% Downside)
The score is primarily constrained by weak financial performance, including a sharp revenue decline, ongoing losses, and leverage risk. Technicals are supportive in trend terms (price above major DMAs and positive MACD) but are tempered by overbought momentum signals (high RSI/Stoch). Valuation is also pressured by negative earnings and no dividend yield data.
Positive Factors
Innovative Product Offering
The innovative diagnostic test positions RHY as a leader in early cancer detection, potentially improving patient outcomes and driving demand.
Growing Market Demand
Increasing demand for early detection tests can lead to higher sales and revenue, supporting long-term growth and market expansion.
Partnership Opportunities
Strategic partnerships can enhance product offerings and provide additional revenue streams, bolstering RHY's competitive position.
Negative Factors
Revenue Decline
Significant revenue decline and ongoing losses indicate challenges in maintaining financial stability and operational efficiency.
Leverage Risk
High leverage can strain financial resources, limiting flexibility and increasing vulnerability to economic downturns.
Negative Cash Flow
Negative cash flow challenges RHY's ability to fund operations and growth initiatives, impacting long-term sustainability.

Rhythm Biosciences Ltd. (RHY) vs. iShares MSCI Australia ETF (EWA)

Rhythm Biosciences Ltd. Business Overview & Revenue Model

Company DescriptionRhythm Biosciences Limited, a transformative predictive cancer diagnostics technology company in Australia and internationally. The company engages in developing and commercializing medical diagnostics technology. It develops ColoSTAT, a blood test for the early detection of colorectal cancer. The company was incorporated in 2017 and is headquartered in Parkville, Australia.
How the Company Makes MoneyRhythm Biosciences generates revenue primarily through the commercialization of its diagnostic tests. The company sells its colorectal cancer test to healthcare providers, laboratories, and hospitals, which then offer these tests to their patients. Additionally, RHY may enter into partnerships or collaborations with larger pharmaceutical or diagnostic companies to expand its market reach and enhance its product offerings. These partnerships can result in upfront payments, royalties, or shared revenue models that contribute to the company's earnings. Furthermore, as awareness and demand for early cancer detection increases, RHY stands to benefit from a growing market, leading to potential increases in sales and revenue over time.

Rhythm Biosciences Ltd. Financial Statement Overview

Summary
Rhythm Biosciences Ltd. faces significant financial challenges, including declining revenues, persistent losses, and high leverage. Despite a high gross profit margin and some improvement in free cash flow, the company needs to address operational inefficiencies and leverage to improve its financial health.
Income Statement
Rhythm Biosciences Ltd. has experienced significant revenue volatility, with a notable decline of 42.87% in the most recent year. The company consistently reports negative net profit margins, indicating ongoing profitability challenges. Despite a high gross profit margin, the negative EBIT and EBITDA margins highlight operational inefficiencies.
Balance Sheet
The company's balance sheet shows a high debt-to-equity ratio of 1.68, suggesting potential leverage risks. Although the equity ratio is relatively stable, the negative return on equity indicates that the company is not generating positive returns for shareholders.
Cash Flow
Rhythm Biosciences Ltd. has shown some improvement in free cash flow growth, but the operating cash flow remains negative, reflecting cash management issues. The free cash flow to net income ratio is slightly above 1, indicating that free cash flow covers net income, albeit both are negative.
BreakdownTTMDec 2025Dec 2024Dec 2023Dec 2022Dec 2021
Income Statement
Total Revenue3.19M3.19M1.69M3.10M2.43M1.11M
Gross Profit372.04K2.97M-1.36M2.91M-101.48K961.86K
EBITDA-3.53M-3.53M-8.35M-11.11M-11.10M-6.46M
Net Income-3.83M-3.83M-6.86M-8.22M-8.79M-6.61M
Balance Sheet
Total Assets2.83M2.83M1.52M7.70M8.44M3.07M
Cash, Cash Equivalents and Short-Term Investments1.48M1.48M754.50K4.17M7.60M2.27M
Total Debt1.11M1.11M163.82K84.61K170.14K0.00
Total Liabilities2.17M2.17M651.54K1.82M1.07M1.36M
Stockholders Equity659.89K659.89K867.17K5.87M7.37M1.71M
Cash Flow
Free Cash Flow-2.94M-2.94M-6.22M-7.06M-6.24M-5.47M
Operating Cash Flow-2.92M-2.92M-6.14M-6.96M-6.21M-5.40M
Investing Cash Flow-582.96K-582.96K-82.28K-99.12K-27.01K-68.27K
Financing Cash Flow4.19M4.19M2.80M3.63M11.85M5.90M

Rhythm Biosciences Ltd. Technical Analysis

Technical Analysis Sentiment
Neutral
Last Price0.14
Price Trends
50DMA
0.09
Positive
100DMA
0.09
Positive
200DMA
0.08
Positive
Market Momentum
MACD
<0.01
Negative
RSI
48.29
Neutral
STOCH
45.17
Neutral
Evaluating momentum and price trends is crucial in stock analysis to make informed investment decisions. For AU:RHY, the sentiment is Neutral. The current price of 0.14 is above the 20-day moving average (MA) of 0.10, above the 50-day MA of 0.09, and above the 200-day MA of 0.08, indicating a neutral trend. The MACD of <0.01 indicates Negative momentum. The RSI at 48.29 is Neutral, neither overbought nor oversold. The STOCH value of 45.17 is Neutral, not indicating any strong overbought or oversold conditions. Overall, these indicators collectively point to a Neutral sentiment for AU:RHY.

Rhythm Biosciences Ltd. Peers Comparison

Overall Rating
UnderperformOutperform
Sector (51)
Financial Indicators
Name
Overall Rating
Market Cap
P/E Ratio
ROE
Dividend Yield
Revenue Growth
EPS Growth
51
Neutral
$7.86B-0.30-43.30%2.27%22.53%-2.21%
48
Neutral
AU$38.65M-5.56-97.79%23.85%
46
Neutral
AU$216.48M-18.01-111.23%12.96%40.81%
45
Neutral
AU$40.44M-7.75-501.54%56.42%
43
Neutral
$5.67M-0.55-56.35%42.80%
41
Neutral
AU$54.51M-2.65-36.16%62.81%16.37%
38
Underperform
AU$55.61M-6.18-37.78%2.33%12.50%
* Healthcare Sector Average
Performance Comparison
Ticker
Company Name
Price
Change
% Change
AU:RHY
Rhythm Biosciences Ltd.
0.10
0.01
16.28%
AU:GTG
Genetic Technologies
0.04
0.00
0.00%
AU:BDX
BCAL Diagnostics Limited
0.11
<0.01
10.00%
AU:LDX
Lumos Diagnostics Holdings Ltd.
0.29
0.25
625.00%
AU:GSS
Genetic Signatures Ltd.
0.24
-0.40
-62.20%
AU:IIQ
Inoviq Ltd
0.39
-0.09
-19.79%

Rhythm Biosciences Ltd. Corporate Events

Rhythm Biosciences Issues New Employee Incentive Options
Dec 23, 2025

Rhythm Biosciences Ltd has issued 31,250 unquoted options under an employee incentive scheme, with each option exercisable at A$0.20 and expiring on 30 November 2027, as notified in an Appendix 3G filing to the ASX. The move underscores the company’s ongoing use of equity-based incentives to attract and retain key staff, aligning employee interests with shareholders and potentially modestly increasing the company’s fully diluted capital base if the options are exercised.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Plans Placement of Up to 625,000 New Shares
Dec 19, 2025

Rhythm Biosciences has notified the ASX of a proposed issue of up to 625,000 ordinary fully paid shares under a placement or similar capital-raising mechanism, with the new securities expected to be issued on 2 February 2026. The move signals an intention to bolster the company’s capital base, which may support ongoing operations and development activities, and could modestly dilute existing shareholders while potentially strengthening Rhythm’s financial position ahead of future milestones.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Plans Securities Issuance for Growth Initiatives
Dec 18, 2025

Rhythm Biosciences Limited has announced a proposed issuance of up to 1,000,000 fully paid ordinary securities, with a scheduled issue date of January 30, 2026. This strategic move could provide the company with additional capital to support its ongoing development efforts and strengthen its positioning in the competitive biotechnology industry.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.10 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Launches ColoSTAT® for Colorectal Cancer Detection
Dec 11, 2025

Rhythm Biosciences Ltd has initiated the commercialization of its ColoSTAT® test, a blood-based diagnostic tool for colorectal cancer, following an updated ISO15189:2022 accreditation. This marks a significant milestone as ColoSTAT® addresses the unmet clinical need for patients where stool-based testing is unsuitable or not preferred. The test will be rolled out through Rhythm’s certified laboratory in Melbourne, with immediate domestic market activities. The company plans to conduct a variation to scope assessment with the National Association of Testing Authorities in January 2026, which would further establish ColoSTAT® as an accredited laboratory service, enhancing clinician confidence and commercial scalability.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Announces CFO Departure Amidst Ongoing Diagnostic Innovations
Dec 10, 2025

Rhythm Biosciences Ltd announced the departure of its Chief Financial Officer, Mr. Todd Perkinson, effective December 19, 2025. This change in leadership comes as the company continues to focus on its mission of providing innovative diagnostic solutions for early cancer detection. The departure could impact the company’s financial strategy and operations, but the board expressed gratitude for Mr. Perkinson’s contributions.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Collaborates with NHS for ColoSTAT® Evaluation
Dec 9, 2025

Rhythm Biosciences Ltd has announced a collaboration with the NHS Southern Hub Research Team to evaluate its ColoSTAT® blood-based test for bowel cancer screening in England. This evaluation is a significant step towards the international commercialization of ColoSTAT®, which could enhance Rhythm’s market positioning by potentially reducing colorectal cancer mortality and healthcare costs.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Partners with Catch Bio to Expand US Market Presence
Dec 8, 2025

Rhythm Biosciences Ltd has entered into a marketing partnership with Catch Bio, a cancer prevention platform, to introduce its geneTypeTM Cancer Risk Assessment Test to Catch Bio’s US member base. This collaboration enhances Catch Bio’s platform by integrating Rhythm’s clinically validated polygenic risk assessment for multiple cancers, supporting Rhythm’s US market expansion strategy. The partnership signifies a commercial milestone for Rhythm, reflecting growing market acceptance of geneTypeTM and expanding its presence in a key global market. The integration of geneTypeTM with Catch Bio’s AI-driven risk model offers a comprehensive risk profile for proactive cancer prevention, marking a significant step in Rhythm’s commitment to early cancer detection.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Updates Director’s Interest Notice
Dec 3, 2025

Rhythm Biosciences Ltd. has announced a change in the director’s interest notice, specifically concerning David Atkins. The update details the acquisition of various securities, including ordinary shares, loan-funded shares, listed options, unlisted options, and deferred shares, following approval at the Annual General Meeting. This change reflects a strategic adjustment in the company’s governance and may influence its market perception and stakeholder confidence.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Announces Director’s Interest Change
Dec 3, 2025

Rhythm Biosciences Ltd. announced a change in the director’s interest, with Gavin Fox-Smith acquiring a significant number of securities, including ordinary shares and options. This acquisition, approved at the Annual General Meeting, reflects strategic moves within the company to align leadership interests with shareholder value, potentially impacting its market positioning and stakeholder confidence.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Announces Director’s Interest Change
Dec 3, 2025

Rhythm Biosciences Ltd. announced a change in the director’s interest, with Sue MacLeman acquiring 450,000 loan funded shares and 450,000 unlisted options, while disposing of 200,000 unlisted options. This change, approved by shareholders at the Annual General Meeting, reflects a strategic adjustment in the company’s governance and may impact its market positioning and stakeholder interests.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Announces Cessation of Securities
Dec 3, 2025

Rhythm Biosciences Ltd. announced the cessation of 200,000 securities due to the lapse of conditional rights, as the conditions were not met by the expiration date of November 30, 2025. This announcement may impact the company’s capital structure and could influence investor perceptions regarding the company’s operational and financial strategies.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Issues New Equity Options Under Employee Incentive Scheme
Dec 3, 2025

Rhythm Biosciences Ltd. announced the issuance of 2,700,000 unquoted equity securities in the form of options expiring on November 30, 2027, with an exercise price of $0.20. This issuance, part of an employee incentive scheme, reflects the company’s strategic efforts to align employee interests with long-term growth objectives, potentially impacting its operational dynamics and market positioning.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Issues New Shares to Bolster Market Position
Dec 3, 2025

Rhythm Biosciences Ltd announced the issuance of 3,333,332 ordinary shares without disclosure under Part 6D.2 of the Corporations Act. The company confirmed compliance with relevant provisions of the Corporations Act and stated there is no excluded information to disclose. This move supports Rhythm’s ongoing efforts in enhancing its financial position to further develop and distribute its diagnostic products, potentially impacting its market presence positively.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Issues Unquoted Equity Securities as Employee Incentives
Dec 3, 2025

Rhythm Biosciences Ltd. announced the issuance of unquoted equity securities, specifically options expiring in 2027 and 2028. This move is part of an employee incentive scheme and is not intended for public trading on the ASX, indicating a strategy to motivate and retain key personnel. The issuance of these options could potentially enhance the company’s operational capabilities by aligning employee interests with long-term company goals.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Issues New Equity Securities to Employees
Dec 2, 2025

Rhythm Biosciences Ltd. announced the issuance of 2,193,001 unquoted equity securities under an employee incentive scheme. This move is part of the company’s strategy to incentivize and retain talent, potentially enhancing its operational capabilities and competitive positioning in the biotechnology sector.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences’ Listed Options Concentrated Among Few Holders
Dec 1, 2025

Rhythm Biosciences Limited has released a report detailing the holdings of its listed options, which are set to expire on November 30, 2027. The report indicates that a significant portion of the options, 96.67%, is held by a small group of 67 holders, with the top holder being HSBC Custody Nominees (Australia) Limited, owning 10.06% of the issued share capital. This concentration of holdings could have implications for the company’s market dynamics and investor relations, as it suggests a limited distribution of shares among a few stakeholders.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Achieves ISO 15189:2022 Accreditation, Paving Way for ColoSTAT® Commercialization
Dec 1, 2025

Rhythm Biosciences Ltd has successfully transitioned its geneType™ Laboratory to the ISO 15189:2022 standard, securing updated accreditation. This achievement allows Rhythm to continue delivering its geneType™ risk assessment service and positions the company to commercialize its ColoSTAT® test as an in-house IVD, pending further assessment. The transition will also help optimize operational costs by eliminating the need for ISO13485 status. This strategic move strengthens Rhythm’s laboratory systems and supports a unified commercial strategy for its products, enhancing market access and operational efficiency.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Validates Ovarian Cancer Risk Model
Dec 1, 2025

Rhythm Biosciences Ltd announced the independent validation of its geneType Ovarian Cancer Risk Prediction Model through the Nurses’ Health Study, confirming its ability to identify twice as many women at elevated risk compared to clinical models alone. This validation supports the model’s clinical utility and aligns with the company’s strategy to enhance personalized and proactive disease management, potentially impacting early detection and prevention strategies in healthcare.

The most recent analyst rating on (AU:RHY) stock is a Hold with a A$0.09 price target. To see the full list of analyst forecasts on Rhythm Biosciences Ltd. stock, see the AU:RHY Stock Forecast page.

Rhythm Biosciences Releases Informational Presentation with Caution on Forward-Looking Statements
Nov 26, 2025

Rhythm Biosciences Limited has released a presentation for general informational purposes, emphasizing that the information provided is not intended as investment advice and may be subject to change. The company highlights that the presentation includes forward-looking statements, which are predictions subject to risks and uncertainties, and advises recipients not to rely on these statements for investment decisions.

Rhythm Biosciences Strengthens Financial Position with R&D Tax Incentive and Loan Repayment
Nov 17, 2025

Rhythm Biosciences Ltd announced the receipt of a $1.571 million Research and Development Tax Incentive and the repayment of a $1 million loan from Endpoints Capital. The company will continue to participate in the Australian Government’s R&D incentive program, which supports its ongoing research efforts. This financial maneuver strengthens Rhythm’s position in the cancer diagnostics industry, allowing it to focus on its mission of early cancer detection and potentially impacting healthcare costs and patient outcomes positively.

Leadership Change at Rhythm Biosciences Ltd.
Nov 5, 2025

Rhythm Biosciences Ltd. has announced a change in its board of directors, with Otto Buttula ceasing to be a director as of November 5, 2025. This change in leadership may impact the company’s strategic direction and stakeholder interests, as it involves significant holdings in the company through various investment entities.

Rhythm Biosciences Secures Strong Shareholder Support at AGM
Nov 5, 2025

Rhythm Biosciences Ltd announced that all resolutions at its Annual General Meeting were passed by poll, reflecting strong shareholder support. This outcome signifies confidence in the company’s strategic direction and ongoing initiatives, potentially strengthening its position in the medical diagnostics industry.

Rhythm Biosciences Appoints New Chair to Lead Next Growth Phase
Nov 5, 2025

Rhythm Biosciences Ltd has appointed Gavin Fox-Smith as the new Chair following the retirement of Otto Buttula. This leadership change marks a new phase for the company, which is known for its innovative cancer diagnostics technology. The transition is expected to support the company’s growth and enhance shareholder value as it continues to develop its cancer detection solutions.

Rhythm Biosciences Updates Stakeholders Post-AGM
Nov 4, 2025

Rhythm Biosciences Ltd. presented a post-AGM update, highlighting ongoing investigations and potential changes in their projects. The presentation underscores the company’s commitment to advancing its research, though it cautions stakeholders about the uncertainties and risks involved, which may impact future operations and market positioning.

Rhythm Biosciences’ ColoSTAT® Shows Consistent Performance Across Age and Gender
Oct 30, 2025

Rhythm Biosciences Ltd announced the successful evaluation of its ColoSTAT® test, which demonstrates consistent performance in detecting colorectal cancer across various age groups and genders. The test shows promise for early onset cancer detection in patients under 50 years old, addressing a growing need in the healthcare industry. The company plans further studies to establish statistical significance and aims for commercial release following regulatory assessments.

Rhythm Biosciences Advances Cancer Diagnostics with Strategic Partnerships and Capital Raise
Oct 28, 2025

Rhythm Biosciences Ltd has announced significant progress in its operations for the first quarter of FY26, highlighted by strategic distribution partnerships for its Genetype product and advancements in the commercial readiness of its ColoSTAT® kits. The company has also successfully raised $3.75 million in capital, indicating strong investor confidence. These developments position Rhythm Biosciences to achieve its strategic objectives for the year, with a focus on commercializing ColoSTAT® and expanding its product offerings.

Rhythm Biosciences Unveils Investor Roadshow Presentation Amid Ongoing Developments
Oct 9, 2025

Rhythm Biosciences Ltd. has released an investor roadshow presentation, highlighting ongoing investigations and developments within the company. While the presentation includes forward-looking statements, it emphasizes that these are subject to change due to various uncertainties. The release underscores the company’s commitment to advancing its diagnostic technologies, although it advises caution regarding the reliance on speculative projections.

Glossary
BuyA stock rated as a "Buy" is expected to perform better than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock is likely to deliver higher returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
HoldA stock rated as a "Hold" is expected to perform in line with the overall market or a specific benchmark. This rating indicates that the stock is neither particularly compelling nor unfavorable for investment. Note: This is not investment advice; please consult a financial advisor before making investment decisions.
SellA stock rated as a "Sell" is expected to perform worse than the overall market or a specific benchmark over the near-to-medium term. This rating suggests the stock may deliver lower returns compared to other stocks in the same sector or market index. Note: This is not investment advice; please consult a financial advisor before making investment decisions.

Disclaimer

This AI Analyst Stock Report is automatically generated by our AI systems using advanced algorithms and publicly available financial, technical, and market data. While the information provided aims to be accurate and insightful, it is intended for informational purposes only and should not be considered financial advice. Any content created by an AI (Artificial Intelligence) system may contain inaccuracies and/or contain errors. Investing in stocks carries inherent risks, and past performance is not indicative of future results. This report does not account for your personal financial circumstances, objectives, or risk tolerance. Always conduct your own research or consult with a qualified financial advisor before making investment decisions. The analysis and recommendations provided are based on historical and current data and may not fully reflect future market conditions or unexpected developments. Neither the creators of this report nor its affiliated entities guarantee the accuracy, completeness, or reliability of the information presented. Use this report at your own discretion and risk.Date of analysis: Dec 31, 2025